{"product_id":"biological-applications-of-microfluidics-9780470074831","title":"Biological Applications of Microfluidics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eMicrofluidics-today's applications and tomorrow's potential  Microfluidics has facilitated major biochemical application advancements in point-of-care diagnostics, bioterrorism detection, and drug discovery. There are numerous potential applications in biotechnology, pharmaceuticals, the life sciences, defense, public health, and agriculture.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"The book has a relatively comprehensive coverage of active areas in the field, and so would serve these markets well.\" (\u003ci\u003eThe Quarterly Review of Biology\u003c\/i\u003e, September 2010)\u003cbr\u003e \u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface.  \u003cp\u003eContributors.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Microfluidics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Microfluidics.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART I CELL ANALYSIS ON MICROFLUIDIC DEVICES.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Using Microfluidics to Understand and Control the Cellular Microenvironment.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction: Engineering the Microenvironment.\u003c\/p\u003e \u003cp\u003e2.2 The Chemical Microenvironment.\u003c\/p\u003e \u003cp\u003e2.3 The Mechanical Microenvironment.\u003c\/p\u003e \u003cp\u003e2.4 Conclusion.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Microfabricated Devices for Cell Sorting.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 Microfabricated Formats for Cell Sorting.\u003c\/p\u003e \u003cp\u003e3.3 Outlook for the Future.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Advanced Microfluidic Tools for Single-Cell Manipulation and Analysis.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 Fluidic Control.\u003c\/p\u003e \u003cp\u003e4.3 Temperature Control.\u003c\/p\u003e \u003cp\u003e4.4 Cell Manipulation.\u003c\/p\u003e \u003cp\u003e4.5 Detection.\u003c\/p\u003e \u003cp\u003e4.6 Integration.\u003c\/p\u003e \u003cp\u003e4.7 Conclusions.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Engineering Cellular Microenvironments with Microfluidics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Microfluidic Cultures can Simulate in vivo Microenvironments.\u003c\/p\u003e \u003cp\u003e5.3 Other Useful Capabilities of Microfluidic Cell Culture Devices.\u003c\/p\u003e \u003cp\u003e5.4 Microfluidic Devices Useful for Cell Applications Other than Culture.\u003c\/p\u003e \u003cp\u003e5.5 Future Prospects for Biological Studies in Microfluidic Bioreactors.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Microfluidic Culture Platforms for Stem Cell and Neuroscience Research.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Applications for Stem Cell Research.\u003c\/p\u003e \u003cp\u003e6.3 Applications for Neuroscience Research.\u003c\/p\u003e \u003cp\u003e6.4 Summary and Future Directions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART II ENZYMATIC AND NONENZYMATIC REACTIONS ON MICROCHIPS.\u003c\/b\u003e\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Microfluidics for Studying Enzyme Inhibition.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Enzyme Assays and Inhibition.\u003c\/p\u003e \u003cp\u003e7.2 Microfluidic Assays for Enzymes and Enzyme Inhibition.\u003c\/p\u003e \u003cp\u003e7.3 Enzyme Inhibition Studies in Microfluidic Devices: Specific Studies.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Chemical Synthesis within Continuous Flow Microreactors.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction.\u003c\/p\u003e \u003cp\u003e8.2 Advantages of Performing Chemical Synthesis in Microreactors.\u003c\/p\u003e \u003cp\u003e8.3 Chemical Synthesis in Microreactors.\u003c\/p\u003e \u003cp\u003e8.4 Large-Scale Manufacture Using Microreactors.\u003c\/p\u003e \u003cp\u003e8.5 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Microfluidic Reactors for Sequential and Parallel Reactions.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction.\u003c\/p\u003e \u003cp\u003e9.2 Sequential Reactions in Microfluidic Devices.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e9.3 Parallel Reactions in Microfluidic Devices.\u003c\/p\u003e \u003cp\u003e9.4 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Gene Isolation, Gene Transformation, and Enzyme Reaction on a Chip.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction.\u003c\/p\u003e \u003cp\u003e10.2 DNA\/RNA Isolation on a Microfluidic Chip.\u003c\/p\u003e \u003cp\u003e10.3 Gene Ligation on a Microfluidic Chip.\u003c\/p\u003e \u003cp\u003e10.4 Gene Transformation on a Chip.\u003c\/p\u003e \u003cp\u003e10.5 Enzymatic Reaction on a Chip.\u003c\/p\u003e \u003cp\u003e10.6 Summary and Perspective.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART III SEPARATIONS ON MICROCHIPS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Chemical Monitoring in Complex Biological Environments Using Separation-Based Sensors in Chips.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Separation-Based Sensors.\u003c\/p\u003e \u003cp\u003e11.2 Fast Separations with Separation-Based Sensors.\u003c\/p\u003e \u003cp\u003e11.3 Micro Total Analysis Systems with Electrophoretic Separations for Monitoring of Biological Systems.\u003c\/p\u003e \u003cp\u003e11.4 Miniaturization and Integration of Separation-Based Sensor Components.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Analytical Strategies Toward the Analysis of Phenolic\u003c\/b\u003e \u003cb\u003eCompounds (Capillary Electrophoresis and Microchip Capillary).\u003c\/b\u003e\u003cbr\u003e \u003c\/p\u003e \u003cp\u003eElectrophoresis.\u003c\/p\u003e \u003cp\u003e12.1 Introduction.\u003c\/p\u003e \u003cp\u003e12.2 Experimental Section.\u003c\/p\u003e \u003cp\u003e12.3 Results and Discussion.\u003c\/p\u003e \u003cp\u003e12.4 Applications.\u003c\/p\u003e \u003cp\u003e12.5 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Chemical Separations in 3D Microfluidics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction.\u003c\/p\u003e \u003cp\u003e13.2 Fabrication.\u003c\/p\u003e \u003cp\u003e13.3 Results and Discussion on 3D Valves.\u003c\/p\u003e \u003cp\u003e13.4 Microfluidic Three-Dimensional Separation Columns.\u003c\/p\u003e \u003cp\u003e13.5 Results on Liquid Chromatography.\u003c\/p\u003e \u003cp\u003e13.6 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Enabling Fundamental Research in Proteomics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction.\u003c\/p\u003e \u003cp\u003e14.2 Membrane Protein Extraction.\u003c\/p\u003e \u003cp\u003e14.3 Conclusion.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART IV BIOMEDICAL APPLICATIONS OF MICROFLUIDICS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Microengineering Neural Development.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction.\u003c\/p\u003e \u003cp\u003e15.2 Microengineering Guidance of Axons to their Targets.\u003c\/p\u003e \u003cp\u003e15.3 Synaptogenesis on a Microfluidic Chip.\u003c\/p\u003e \u003cp\u003e15.4 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Applications of Centrifugal Microfluidics in Biology.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Introduction.\u003c\/p\u003e \u003cp\u003e16.2 Why Use Centrifugal Force for Fluid Manipulation?\u003c\/p\u003e \u003cp\u003e16.3 How Centrifugal Microfluidic Platforms Work.\u003c\/p\u003e \u003cp\u003e16.4 CD Applications.\u003c\/p\u003e \u003cp\u003e16.5 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Microfluidic Techniques for Point-of-Care\u003c\/b\u003e \u003cb\u003eIn Vitro Diagnostics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17.1 Introduction.\u003c\/p\u003e \u003cp\u003e17.2 Microfluidic Immunoassays.\u003c\/p\u003e \u003cp\u003e17.3 Microfluidic Vias and Derivative Applications.\u003c\/p\u003e \u003cp\u003e17.4 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART V MICROFLUIDIC FABRICATION STUDIES.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Fabrication of Polymeric Microfluidic Devices.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18.1 Introduction.\u003c\/p\u003e \u003cp\u003e18.2 Glass- and Silicon-Based Materials.\u003c\/p\u003e \u003cp\u003e18.3 Plastics and Polymeric Materials.\u003c\/p\u003e \u003cp\u003e18.4 Approaches to Microfabrication.\u003c\/p\u003e \u003cp\u003e18.5 Selected Microfabrication Techniques.\u003c\/p\u003e \u003cp\u003e18.6 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Nano Fountain Pen: Toward Integrated, Portable, Lab-on-Chip Devices.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19.1 Introduction.\u003c\/p\u003e \u003cp\u003e19.2 Nano Fountain Pen.\u003c\/p\u003e \u003cp\u003e19.3 Protein Printing.\u003c\/p\u003e \u003cp\u003e19.4 Enzyme Lithography.\u003c\/p\u003e \u003cp\u003e19.5 Polymer Microlenses.\u003c\/p\u003e \u003cp\u003e19.6 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Surface Engineering of Microfluidic Devices Using Reactive Polymer Coatings.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20.1 Introduction.\u003c\/p\u003e \u003cp\u003e20.2 Microfluidics Surface Modification Techniques.\u003c\/p\u003e \u003cp\u003e20.3 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Microchips Containing\u003c\/b\u003e \u003cb\u003eIn Situ Patterned Polymeric Media for Biochemical Analysis.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e21.1 Introduction and Scope.\u003c\/p\u003e \u003cp\u003e21.2 General Information about Patterned Materials.\u003c\/p\u003e \u003cp\u003e21.3 Photopatterned Materials for Protein Analysis.\u003c\/p\u003e \u003cp\u003e21.4 DNA Purification and Analysis.\u003c\/p\u003e \u003cp\u003e21.5 Patterned Materials for Cell Culture and Analysis.\u003c\/p\u003e \u003cp\u003e21.6 Other Biomolecules.\u003c\/p\u003e \u003cp\u003e21.7 Conclusions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART VI HYBRID MICROFLUIDIC APPLICATIONS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Coupling Electrochemistry to Microfluidics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22.1 Introduction.\u003c\/p\u003e \u003cp\u003e22.2 Electrochemical Methods of Analysis.\u003c\/p\u003e \u003cp\u003e22.3 Microfluidic Devices.\u003c\/p\u003e \u003cp\u003e22.4 Applications.\u003c\/p\u003e \u003cp\u003e22.5 Conclusions and Future Directions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 Manipulating Mass-Limited Samples Using Hybrid Microfluidic\/Nanofluidic Networks.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e23.1 Introduction.\u003c\/p\u003e \u003cp\u003e23.2 Nanofluidics.\u003c\/p\u003e \u003cp\u003e23.3 Hybrid Microfluidic\/Nanofluidic Systems.\u003c\/p\u003e \u003cp\u003e23.4 Functionalized NCAMs.\u003c\/p\u003e \u003cp\u003e23.5 The Future.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 Magnetic Bead-based Methods to Study the Interaction of Teicoplanin with Peptides and Bacteria.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e24.1 Introduction.\u003c\/p\u003e \u003cp\u003e24.2 Experimental.\u003c\/p\u003e \u003cp\u003e24.3 Results and Discussion.\u003c\/p\u003e \u003cp\u003e24.4 Conclusions.\u003c\/p\u003e \u003cp\u003eAcknowledgments.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e25 Interfacing Microchannel Electrophoresis with Electrospray Ionization Mass Spectrometry.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e25.1 Introduction.\u003c\/p\u003e \u003cp\u003e25.2 Electrospray Ionization.\u003c\/p\u003e \u003cp\u003e25.3 Coatings.\u003c\/p\u003e \u003cp\u003e25.4 Spray Emitters.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e25.5 CE and ESI Electrode Connections.\u003c\/p\u003e \u003cp\u003e25.6 Integrated Applications.\u003c\/p\u003e \u003cp\u003e25.7 Conclusions.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402279952727,"sku":"9780470074831","price":128.66,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470074831.jpg?v=1730479930","url":"https:\/\/bookcurl.com\/products\/biological-applications-of-microfluidics-9780470074831","provider":"Book Curl","version":"1.0","type":"link"}