{"product_id":"biochemistry-9781119610557","title":"Biochemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003e1 \u003c\/b\u003e\u003cb\u003eThe Chemical Foundations of Biochemistry 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChemistry in Context 1\u003c\/p\u003e \u003cp\u003e1.1 General Chemical Principles 2\u003c\/p\u003e \u003cp\u003e1.2 Fundamental Concepts of Organic Chemistry 11\u003c\/p\u003e \u003cp\u003e1.3 The Chemistry of Water 15\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 \u003c\/b\u003e\u003cb\u003eNucleic Acids 26\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNucleic Acids in Context 26\u003c\/p\u003e \u003cp\u003e2.1 Nucleic Acids Have Distinct Structures 27\u003c\/p\u003e \u003cp\u003e2.2 Nucleic Acids Have Many Cellular Functions 37\u003c\/p\u003e \u003cp\u003e2.3 The Manipulation of Nucleic Acids Has Transformed Biochemistry 45\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 \u003c\/b\u003e\u003cb\u003eProteins I: An Introduction to Protein Structure and Function 67\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProteins in Context 67\u003c\/p\u003e \u003cp\u003e3.1 Amino Acid Chemistry 69\u003c\/p\u003e \u003cp\u003e3.2 Proteins Are Polymers of Amino Acids 74\u003c\/p\u003e \u003cp\u003e3.3 Proteins Are Molecules of Defined Shape and Structure 79\u003c\/p\u003e \u003cp\u003e3.4 Examples of Protein Structures and Functions 89\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 \u003c\/b\u003e\u003cb\u003eProteins II: Enzymes 101\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eEnzymes in Context 101\u003c\/p\u003e \u003cp\u003e4.1 Regarding Enzymes 103\u003c\/p\u003e \u003cp\u003e4.2 Enzymes Increase Reaction Rate 108\u003c\/p\u003e \u003cp\u003e4.3 The Mechanism of an Enzyme Can Be Deduced from Structural, Kinetic, and Spectral Data 117\u003c\/p\u003e \u003cp\u003e4.4 Examples of Enzyme Regulation 127\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 \u003c\/b\u003e\u003cb\u003eMembranes and an Introduction to Signal Transduction 138\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eBiochemistry in Context 138\u003c\/p\u003e \u003cp\u003e5.1 Membrane Structure and Function 139\u003c\/p\u003e \u003cp\u003e5.2 Signal Transduction 149\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 \u003c\/b\u003e\u003cb\u003eCarbohydrates I: Mono- and Disaccharides, Glycolysis, Gluconeogenesis, and the Fates of Pyruvate 161\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eCarbohydrates in Context 161\u003c\/p\u003e \u003cp\u003e6.1 Properties, Nomenclature, and Biological Functions of Monosaccharides 163\u003c\/p\u003e \u003cp\u003e6.2 Properties, Nomenclature, and Biological Functions of Complex Carbohydrates 170\u003c\/p\u003e \u003cp\u003e6.3 Glycolysis and an Introduction to Metabolic Pathways 177\u003c\/p\u003e \u003cp\u003e6.4 Gluconeogenesis 193\u003c\/p\u003e \u003cp\u003e6.5 The Fates of Pyruvate 196\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 \u003c\/b\u003e\u003cb\u003eThe Common Catabolic Pathway: Citric Acid Cycle, the Electron Transport Chain, and ATP Biosynthesis 209\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eElectron Transport in Context 209\u003c\/p\u003e \u003cp\u003e7.1 The Citric Acid Cycle 211\u003c\/p\u003e \u003cp\u003e7.2 The Electron Transport Chain 223\u003c\/p\u003e \u003cp\u003e7.3 ATP Biosynthesis 241\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 \u003c\/b\u003e\u003cb\u003eCarbohydrates II: Glycogen Metabolism, the Pentose Phosphate Pathway, Glycoconjugates, and Extracellular Matrices 253\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePolysaccharides in Context 253\u003c\/p\u003e \u003cp\u003e8.1 Glycogen Metabolism 255\u003c\/p\u003e \u003cp\u003e8.2 The Pentose Phosphate Pathway 264\u003c\/p\u003e \u003cp\u003e8.3 Carbohydrates in Glycoconjugates 273\u003c\/p\u003e \u003cp\u003e8.4 Extracellular Matrices and Biofilms 284\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 \u003c\/b\u003e\u003cb\u003eLipids I: Fatty Acids, Steroids, and Eicosanoids; Beta-Oxidation and Fatty Acid Biosynthesis 300\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eLipids in Context 300\u003c\/p\u003e \u003cp\u003e9.1 Properties, Nomenclature, and Biological Functions of Lipid Molecules 302\u003c\/p\u003e \u003cp\u003e9.2 Fatty Acid Catabolism 311\u003c\/p\u003e \u003cp\u003e9.3 Fatty Acid Biosynthesis 317\u003c\/p\u003e \u003cp\u003e9.4 Ketone Body Metabolism 329\u003c\/p\u003e \u003cp\u003e9.5 Steroid Metabolism 332\u003c\/p\u003e \u003cp\u003e9.6 Eicosanoid and Endocannabinoid Metabolism 339\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 \u003c\/b\u003e\u003cb\u003eLipids II: Metabolism and Transport of Complex Lipids 351\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eComplex Lipids in Context 351\u003c\/p\u003e \u003cp\u003e10.1 Phospholipid Metabolism 353\u003c\/p\u003e \u003cp\u003e10.2 Digestion of Triacylglycerols 361\u003c\/p\u003e \u003cp\u003e10.3 Transport of Lipids in the Circulation 367\u003c\/p\u003e \u003cp\u003e10.4 Entry of Lipids into the Cell 377\u003c\/p\u003e \u003cp\u003e10.5 Neutral Lipid Biosynthesis 380\u003c\/p\u003e \u003cp\u003e10.6 Lipid Storage Droplets, Fat Storage, and Mobilization 384\u003c\/p\u003e \u003cp\u003e10.7 Lipid Rafts as a Biochemical Entity 388\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 \u003c\/b\u003e\u003cb\u003eAmino Acid and Amine Metabolism 397\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAmine Metabolism in Context 397\u003c\/p\u003e \u003cp\u003e11.1 Digestion of Proteins 399\u003c\/p\u003e \u003cp\u003e11.2 Transamination and Oxidative Deamination 404\u003c\/p\u003e \u003cp\u003e11.3 The Urea Cycle 409\u003c\/p\u003e \u003cp\u003e11.4 Pathways of Amino Acid Carbon Skeleton Scavenging 414\u003c\/p\u003e \u003cp\u003e11.5 The Detoxification of Other Amines and Xenobiotics 423\u003c\/p\u003e \u003cp\u003e11.6 The Biochemistry of Renal Function 429\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 \u003c\/b\u003e\u003cb\u003eRegulation and Integration of Metabolism 440\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMetabolism in Context 440\u003c\/p\u003e \u003cp\u003e12.1 A Review of the Pathways and Crossroads of Metabolism 442\u003c\/p\u003e \u003cp\u003e12.2 Organ Specialization and Metabolic States 446\u003c\/p\u003e \u003cp\u003e12.3 Communication between Organs 455\u003c\/p\u003e \u003cp\u003e12.4 Metabolic Disease 463\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 \u003c\/b\u003e\u003cb\u003eNucleotide and Deoxynucleotide Metabolism 477\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNucleotides and Deoxynucleotides in Context 477\u003c\/p\u003e \u003cp\u003e13.1 Purine Biosynthesis 478\u003c\/p\u003e \u003cp\u003e13.2 Pyrimidine Biosynthesis 484\u003c\/p\u003e \u003cp\u003e13.3 Deoxyribonucleotide Biosynthesis 489\u003c\/p\u003e \u003cp\u003e13.4 Catabolism of Nucleotides 495\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 \u003c\/b\u003e\u003cb\u003eDNA Replication, Damage, and Repair 506\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDNA in Context 506\u003c\/p\u003e \u003cp\u003e14.1 Challenges of DNA Replication 507\u003c\/p\u003e \u003cp\u003e14.2 DNA Replication in Prokaryotes 512\u003c\/p\u003e \u003cp\u003e14.3 DNA Replication in Eukaryotes 517\u003c\/p\u003e \u003cp\u003e14.4 DNA Damage and Repair 523\u003c\/p\u003e \u003cp\u003e14.5 Homologous Recombination 534\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 \u003c\/b\u003e\u003cb\u003eRNA Synthesis and Processing 546\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eRNA Synthesis in Context 546\u003c\/p\u003e \u003cp\u003e15.1 Transcription: RNA Synthesis 548\u003c\/p\u003e \u003cp\u003e15.2 Processing of Nascent Eukaryotic RNA Messages 557\u003c\/p\u003e \u003cp\u003e15.3 RNA Export from the Nucleus 566\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 \u003c\/b\u003e\u003cb\u003eProtein Synthesis 576\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProtein Synthesis in Context 576\u003c\/p\u003e \u003cp\u003e16.1 The Genetic Code 577\u003c\/p\u003e \u003cp\u003e16.2 RNA Structure Function in Protein Biosynthesis 580\u003c\/p\u003e \u003cp\u003e16.3 Protein Biosynthesis 585\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 \u003c\/b\u003e\u003cb\u003eControl and Regulation of Gene Expression 606\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eGene Regulation in Context 606\u003c\/p\u003e \u003cp\u003e17.1 DNA–Protein Interactions 607\u003c\/p\u003e \u003cp\u003e17.2 Regulation of Expression in Prokaryotes 613\u003c\/p\u003e \u003cp\u003e17.3 Regulation of Expression in Eukaryotes 623\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 \u003c\/b\u003e\u003cb\u003eDetermination of Macromolecular Structure 649\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMacromolecular Structure in Context 649\u003c\/p\u003e \u003cp\u003e18.1 An Introduction to Structure Determination 650\u003c\/p\u003e \u003cp\u003e18.2 Electron Microscopy 654\u003c\/p\u003e \u003cp\u003e18.3 X-Ray Diffraction and Neutron Scattering 658\u003c\/p\u003e \u003cp\u003e18.4 Nuclear Magnetic Resonance 668\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 \u003c\/b\u003e\u003cb\u003eAllosterism and Receptor–Ligand Interactions 679\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAllosterism in Context 679\u003c\/p\u003e \u003cp\u003e19.1 Allosterism and Cooperativity 680\u003c\/p\u003e \u003cp\u003e19.2 Hemoglobin 686\u003c\/p\u003e \u003cp\u003e19.3 Receptor–Ligand Interactions 696\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 \u003c\/b\u003e\u003cb\u003eDesigner Proteins and Protein Folding 706\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProtein Engineering and Folding in Context 706\u003c\/p\u003e \u003cp\u003e20.1 Protein Production 707\u003c\/p\u003e \u003cp\u003e20.2 Protein Engineering 714\u003c\/p\u003e \u003cp\u003e20.3 Protein Folding 724\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 \u003c\/b\u003e\u003cb\u003eBiomolecule Purification 736\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProtein Purification in Context 736\u003c\/p\u003e \u003cp\u003e21.1 Protein Purification Basics 737\u003c\/p\u003e \u003cp\u003e21.2 Size-Exclusion Chromatography 745\u003c\/p\u003e \u003cp\u003e21.3 Affinity Chromatography 751\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 \u003c\/b\u003e\u003cb\u003eBioinformatics and Omics 764\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eBioinformatics in Context 764\u003c\/p\u003e \u003cp\u003e22.1 Introduction to Bioinformatics 765\u003c\/p\u003e \u003cp\u003e22.2 Generating Bioinformatic Data 769\u003c\/p\u003e \u003cp\u003e22.3 Analyzing Bioinformatic Data 778\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 \u003c\/b\u003e\u003cb\u003eSignal Transduction 790\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eCell Signaling in Context 790\u003c\/p\u003e \u003cp\u003e23.1 A Review of Signal Transduction 791\u003c\/p\u003e \u003cp\u003e23.2 An Overview of Regulation of Signal Transduction 797\u003c\/p\u003e \u003cp\u003e23.3 Six New Signal Transduction Pathways 800\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 \u003c\/b\u003e\u003cb\u003eProtein Trafficking 821\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProtein Trafficking in Context 821\u003c\/p\u003e \u003cp\u003e24.1 Molecular Aspects of Protein Trafficking 822\u003c\/p\u003e \u003cp\u003e24.2 Molecular Motors 827\u003c\/p\u003e \u003cp\u003e24.3 Vesicular Fusion 834\u003c\/p\u003e \u003cp\u003e\u003cb\u003e25 \u003c\/b\u003e\u003cb\u003ePhotosynthesis and Nitrogen Fixation 841\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePhotosynthesis and Nitrogen Fixation in Context 841\u003c\/p\u003e \u003cp\u003e25.1 Photosynthesis 842\u003c\/p\u003e \u003cp\u003e25.2 Nitrogen Fixation 859\u003c\/p\u003e \u003cp\u003eTechniques T-1\u003c\/p\u003e \u003cp\u003esolutions A-1\u003c\/p\u003e \u003cp\u003eGlossary G-1\u003c\/p\u003e \u003cp\u003eIndex I-1\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default 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