{"product_id":"bacterial-resistance-to-antibiotics-9781119940777","title":"Bacterial Resistance to Antibiotics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eAN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant Superbugs. The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths.    Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic erawhen diseases caused by parasites or infections were virtually untreatable and frequently resulted in deathnew and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics.    Bacterial Resistance to Antibiotics  From Molecules to Manexamines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more.    Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradabilityHighlights critical aspects that may relieve the problematic medical situation of antibiotic resistanceIncludes an overview of the genetic and molecular mechanisms of antibiotic resistanceAddresses contemporary issues of global public health and longevityIncludes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics  From Molecules to Manis a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of Contributors vii\u003c\/p\u003e \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eForeword xiii\u003cbr\u003e\u003ci\u003eAda Yonath\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1 Molecular Mechanisms of Antibiotic Resistance – Part I 1\u003cbr\u003e\u003ci\u003eAlison J. Baylay, Laura J.V. Piddock, and Mark A. Webber\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Molecular Mechanisms of Antibiotic Resistance – Part II 27\u003cbr\u003e\u003ci\u003eLiam K.R. Sharkey and Alex J. O’Neill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Resistance to Glycopeptide Antibiotics 51\u003cbr\u003e\u003ci\u003eFrançois Lebreton and Vincent Cattoir\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Resistance and Tolerance to Aminoglycosides 81\u003cbr\u003e\u003ci\u003eWendy W.K. Mok and Mark P. Brynildsen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Tetracyclines: Mode of Action and their Bacterial Mechanisms of Resistance 101\u003cbr\u003e\u003ci\u003eMarilyn C. Roberts\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Fluoroquinolone Resistance 125\u003cbr\u003e\u003ci\u003eKarl Drlica, Xilin Zhao, Muhammad Malik, Hiroshi Hiasa, Arkady Mustaev, and Robert Kerns\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Dihydropteroate Synthase (Sulfonamides) and Dihydrofolate Reductase Inhibitors 163\u003cbr\u003e\u003ci\u003eClemente Capasso and Claudiu T. Supuran\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Anti‐tuberculosis Agents 173\u003cbr\u003e\u003ci\u003eYing Zhang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Multidrug Resistance 201\u003cbr\u003e\u003ci\u003eRobert L. Marshall and Vassiliy N. Bavro\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Anti‐virulence Therapies Through Potentiating ROS in Bacteria 239\u003cbr\u003e\u003ci\u003eKristin J. Adolfsen and Mark P. Brynildsen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 255\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":49407191089495,"sku":"9781119940777","price":61.92,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119940777.jpg?v=1730498496","url":"https:\/\/bookcurl.com\/products\/bacterial-resistance-to-antibiotics-9781119940777","provider":"Book Curl","version":"1.0","type":"link"}