{"product_id":"automation-in-proteomics-and-genomics-9780470727232","title":"Automation in Proteomics and Genomics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIn the last decade DNA sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools, technologies and process improvements. Further cost reductions in this and in related proteomics technologies are expected as a result of the development of new high-throughput techniques and the computational machinery needed to analyze data generated.  \u003cp\u003e\u003ci\u003eAutomation in Proteomics \u0026amp; Genomics: An Engineering Case-Based Approach\u003c\/i\u003e describes the automation technology currently in the areas of analysis, design, and integration, as well as providing basic biology concepts behind proteomics and genomics. The book also discusses the current technological limitations that can be viewed as an emerging market rather than a research bottleneck. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cdiv\u003emolecular biology fundamentals: from blueprint' (DNA) to task list' (RNA) to molecular machine' (protein); proteomics methods and technologies; modelling protein\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e\u003ci\u003ePreface.\u003c\/i\u003e\u003c\/b\u003e  \u003cp\u003e\u003cb\u003e\u003ci\u003eList of Contributors.\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e\u003ci\u003eAbout the Editors.\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 1 FUNDAMENTALS OF MOLECULAR AND CELLULAR BIOLOGY\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 The Central Dogma: From DNA to RNA, and to Protein\u003c\/b\u003e (\u003ci\u003eTakashi Ohtsuki, Masahiko Sisido).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Genomes to Proteomes\u003c\/b\u003e (\u003ci\u003eEllen A. Panisko, Igor Grigoriev, Don S. Daly, Bobbie-Jo Webb-Robertson and Scott E. Baker).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 2 ANALYSIS VIA AUTOMATION.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 High-Throughput DNA Sequencing\u003c\/b\u003e (\u003ci\u003eTarjei S. Mikkelsen).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Modeling a Regulatory Network Using Temporal Gene Expression Data: Why and How\u003c\/b\u003e (\u003ci\u003eSophie L`ebre and Gäelle Lelandais)?\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Automated Prediction of Protein Attributes and Its Impact on Biomedicine and Drug Discovery\u003c\/b\u003e (\u003ci\u003eKuo-Chen Chou).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Molecular Interaction Networks: Topological and Functional Characterizations\u003c\/b\u003e (\u003ci\u003eXiaogang Wu and Jake Y. Chen).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 3 DESIGN VIA AUTOMATION.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 DNA Synthesis\u003c\/b\u003e (\u003ci\u003eJingdong Tian).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Computational and Experimental RNA Nanoparticle Design\u003c\/b\u003e (\u003ci\u003eIsil Severcan, Cody Geary, Luc Jaeger, Eckart Bindewald, Wojciech\u003c\/i\u003e \u003ci\u003eKasprzak and Bruce A. Shapiro).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 New Paradigms in Droplet-Based Microfluidics and DNA Amplification\u003c\/b\u003e (\u003ci\u003eMichael L. Samuels, John Leamon, Jonathan Rothberg, Ronald Godiska,\u003c\/i\u003e\u003ci\u003eThomas Schoenfeld and David Mead).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Synthetic Networks\u003c\/b\u003e (\u003ci\u003eJongmin Kim).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 4 INTEGRATION.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Molecular Modeling of CYP Proteins and its Implication for Personal Drug Design\u003c\/b\u003e (\u003ci\u003eJing-Fang Wang, Cheng-Cheng Zhang, Jing-Yi Yan, Kuo-Chen Chou and\u003c\/i\u003e \u003ci\u003eDong-Qing Wei).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Recent Progress of Bioinformatics in Membrane Protein Structural Studies\u003c\/b\u003e (\u003ci\u003eHong-Bin Shen, Jun-Feng Wang, Li-Xiu Yao, Jie Yang and Kuo-Chen Chou).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Trends in Automation for Genomics and Proteomics\u003c\/b\u003e (\u003ci\u003eGil Alterovitz, Roseann Benson, Marco Ramoni and Dmitriy Sonkin).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e\u003ci\u003eIndex.\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402419872087,"sku":"9780470727232","price":111.56,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/automation-in-proteomics-and-genomics-9780470727232","provider":"Book Curl","version":"1.0","type":"link"}