{"product_id":"atherosclerosis-9781118285916","title":"Atherosclerosis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eComprehensive and in-depth in its coverage,\u003ci\u003eAtherosclerosis: Cellular, Molecular \u0026amp; Biochemical Mechanism and Novel Therapy\u003c\/i\u003e reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAtherosclerosis: Cellular, Molecular \u0026amp; Biochemical Mechanism and Novel Therapy\u003c\/i\u003e analyses recent progress from both conceptual and technological perspectives, suggesting new directions for atherosclerosis research and treatment for a growing population of researchers and clinicians in cardiovascular and related fields.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003eForeword\u003cbr\u003e\u003ci\u003eJoseph Loscalzo \u003c\/i\u003exv\u003c\/p\u003e \u003cp\u003ePreface\u003cbr\u003e\u003ci\u003eEric N. Olson \u003c\/i\u003exvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection I: Risk Factors: Old and New 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Lipoproteins 3\u003cbr\u003e\u003ci\u003eMing-Lin Liu and Daniel J. Rader\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Role of Dysglycemia in Atherosclerosis 15\u003cbr\u003e\u003ci\u003eDavid R. Clemmons\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Glycation, Inflammation and RAGE: Mechanisms Contributing to the Accelerated Atherosclerosis of Diabetes 27\u003cbr\u003e\u003ci\u003eRavichandran Ramasamy, Shi Fang Yan, and Ann Marie Schmidt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Inflammation 43\u003cbr\u003e\u003ci\u003eCaitlin Collins, Ellie Tzima, and Cam Patterson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Homocysteine: A Controversial Cardiovascular Risk Factor 53\u003cbr\u003e\u003ci\u003eSanjana Dayal and Steven R. Lentz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Hypertension as a Risk Factor for Atherosclerosis 63\u003cbr\u003e\u003ci\u003eAnnet Kirabo and David G. Harrison\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 The Genetics of Atherosclerosis: From Polymorphisms to Populations 77\u003cbr\u003e\u003ci\u003ePaul Johnson, Jack Kuritzky, and Marschall Runge\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Life Style 93\u003cbr\u003e\u003ci\u003eWayne E. Cascio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection II: Cellular Mechanisms 105\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9 Endothelial Cells 107\u003cbr\u003e\u003ci\u003eG. Brandon Atkins, Gabriela Orasanu, and Mukesh K. Jain\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Vascular Smooth Muscle Cells 117\u003cbr\u003e\u003ci\u003eDario F. Riascos-Bernal and Nicholas E. S. Sibinga\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Fibroblasts 129\u003cbr\u003e\u003ci\u003eChristopher Mack\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Monocytes and Macrophages in Atherosclerosis 141\u003cbr\u003e\u003ci\u003eShu Meng, Pu Fang, Xiaofeng Yang, and Hong Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Lymphocytes and Atherosclerosis 155\u003cbr\u003e\u003ci\u003eAnthony Virtue, Jietang Mai, Hong Wang, and Xiaofeng Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Stem Cells 173\u003cbr\u003e\u003ci\u003eArjun Deb\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Platelets 187\u003cbr\u003e\u003ci\u003eJerry Ware and Adam Corken\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Development and Use of Mouse Models of Atherosclerosis 197\u003cbr\u003e\u003ci\u003ePeggy Robinet and Jonathan D. Smith\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection III: Molecular Mechanisms 207\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17 Mechanisms of the Renin Angiotensin System Influencing Atherosclerosis 209\u003cbr\u003e\u003ci\u003eHong Lu and Alan Daugherty\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 The Role of Caveolae and Caveolins in Atherogenesis 221\u003cbr\u003e\u003ci\u003eVictor Rizzo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Lysosomal Molecular Derangements in Atherosclerosis 235\u003cbr\u003e\u003ci\u003ePin-Lan Li and Yang Zhang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 C-Reactive Protein and Its Pathophysiological Roles in Atherosclerosis 247\u003cbr\u003e\u003ci\u003eJianglin Fan, Jifeng Zhang, and Yuqing Eugene Chen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Paraoxonases 257\u003cbr\u003e\u003ci\u003eSrinivasa T. Reddy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Prostanoids, Their Receptors, and Atherogenesis 267\u003cbr\u003e\u003ci\u003eDomenico Praticò\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Extracellular Phospholipases: Role in Inflammation and Atherosclerotic Cardiovascular Disease 279\u003cbr\u003e\u003ci\u003eUwe J.F. Tietge\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Apolipoprotein-B: The Crucial Protein of Atherogenic Lipoproteins 291\u003cbr\u003e\u003ci\u003eKevin Jon Williams and Edward A. Fisher\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 HDL Receptor Scavenger Receptor BI: A Multipurpose Player in Cholesterol and Steroid Metabolism in Mice and Man 313\u003cbr\u003e\u003ci\u003eYing Zhao, Menno Hoekstra, Suzanne J. A. Korporaal, Theo J. C. Van Berkel, and Miranda Van Eck\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Pro and Anti-Inflammatory Cytokine Networks in Atherosclerosis 329\u003cbr\u003e\u003ci\u003eMichael V. Autieri\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 E CM and Atherosclerosis 343\u003cbr\u003e\u003ci\u003eJie Du, Ying Wang, and Lixin Jia\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection IV: Biochemical Mechanisms 353\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e28 Effects of Nitric Oxide on Atherosclerosis 355\u003cbr\u003e\u003ci\u003eTerrence Pong and Paul L. Huang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Protective Role of Heme Oxygenase-1 in Atherosclerosis 365\u003cbr\u003e\u003ci\u003eWilliam Durante\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Roles of Reactive Oxygen Species in Physiology and Pathology 379\u003cbr\u003e\u003ci\u003ePing Song and Ming-Hui Zou\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Hydrogen Sulfide: Role in Atherosclerosis, Mechanisms, and Therapeutic Potential 393\u003cbr\u003e\u003ci\u003eElvis A. Peter, Jai Varma, and Christopher G. Kevil\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 Methylation and Atherosclerosis 405\u003cbr\u003e\u003ci\u003eXin-Yu Xiong, Shu Meng, Xiaofeng Yang, and Hong Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 Micromanaging Atherogenesis: Role of Micrornas in Atherosclerosis 423\u003cbr\u003e\u003ci\u003eShusheng Wang and Chastain Anderson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Posttranslational Modifications: Role in Atherosclerosis 437\u003cbr\u003e\u003ci\u003eJustyna Fert-Bober, Ronald J. Holewinski, Joel A. Kooren, and Jennifer E. Van Eyk\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Phosphorylation Regulation by Kinases and Phosphatases in Atherosclerosis 453\u003cbr\u003e\u003ci\u003eKatherine J. Elliott and Satoru Eguchi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e36 Effect of MMPs on Cardiovasculature and Blood Flow: Role of Ros, Mitophagy, and Antioxidants 467\u003cbr\u003e\u003ci\u003eThomas P. Vacek, Diana Neamtu, and Suresh C. Tyagi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection V: Clinical Management 479\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e37 Impact of Preventive Therapies on Clinical Management and Outcomes 481\u003cbr\u003e\u003ci\u003eDanny Eapen, Ahsan Achtchi, Reynaria Nieva, Kiran Valiani, Faresa Zarreen, Aalok Patel, Allen Dollar, Ijeoma Isiadinso, Susmita Parashar, Jefferson Baer, Kreton Mavromatis, and Laurence Sperling\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e38 Risk Stratification in Clinical Practice 495\u003cbr\u003e\u003ci\u003ePhil Mendys, Golsa Joodi, and Ross J. Simpson, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e39 Molecular Imaging 503\u003cbr\u003e\u003ci\u003eArun K. Thukkani and Farouc A. Jaffer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e40 Pharmacological Therapy in the Management of Acute Coronary Syndromes 517\u003cbr\u003e\u003ci\u003eAndrew J. Sampson, Timir Paul, and George A. Stouffer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e41 Targeted Molecular Therapeutics for Atherosclerosis 533\u003cbr\u003e\u003ci\u003eLantz C. Mackey and Jonathon W. Homeister\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e42 High-Density Lipoprotein Therapies—Then and Now 545\u003cbr\u003e\u003ci\u003eHenry J. Pownall, Corina Rosales, Baiba K. Gillard, and Antonio M. Gotto, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e43 Stem Cell Therapeutics 557\u003cbr\u003e\u003ci\u003eMei Mei Wong and Qingbo Xu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e44 Advances in Surgical Revascularization 567\u003cbr\u003e\u003ci\u003eStephen J. Forest, Ahmed Khan, and Joseph J. DeRose, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 579\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":49406845976919,"sku":"9781118285916","price":148.45,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/atherosclerosis-9781118285916","provider":"Book Curl","version":"1.0","type":"link"}