{"product_id":"aptamers-in-bioanalysis-9780470148303","title":"Aptamers in Bioanalysis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis is the first book to detail bioanalytical technologies and methods that have been developed using aptamers in analytical, medical, environmental, and food science applications.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e?This book provides descriptions of many applications of aptamers for biosensing, and for this reason, it is very useful and an interesting read.? (\u003ci\u003eJACS\u003c\/i\u003e , August 2009)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cb\u003ePREFACE.\u003c\/b\u003e  \u003cp\u003e\u003cb\u003eCONTRIBUTORS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eI INTRODUCTION.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 APTAMERS: LIGANDS FOR ALL REASONS\u003c\/b\u003e (\u003ci\u003eJean-Jacques Toulme , Jean-Pierre Daguer, and Eric Dausse\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e1.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.2 The Power of Selection and Aptamer Refinement.\u003c\/p\u003e \u003cp\u003e1.3 The Chemistry Drives the Shape.\u003c\/p\u003e \u003cp\u003e1.4 Aptaregulators.\u003c\/p\u003e \u003cp\u003e1.5 Aptasensors.\u003c\/p\u003e \u003cp\u003e1.6 Prospects.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 SELEX AND ITS RECENT OPTIMIZATIONS\u003c\/b\u003e (\u003ci\u003eBeate Strehlitz and Regina Stoltenburg\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.2 Aptamers and Their Selection by SELEX.\u003c\/p\u003e \u003cp\u003e2.3 Modifications of SELEX Technology.\u003c\/p\u003e \u003cp\u003e2.4 Advantages and Limitations of Aptamers and Their Selection Technology.\u003c\/p\u003e \u003cp\u003e2.5 Applications of Aptamers Being Developed for the Market.\u003c\/p\u003e \u003cp\u003e2.6 Future Perspectives.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eII BIOSENSORS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 ELECTROCHEMICAL APTASENSORS\u003c\/b\u003e (\u003ci\u003eItamar Willner and Maya Zayats\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 Electrochemical Aptasensor Based on Redox-Active Aptamer Monolayers Linked to Electrodes.\u003c\/p\u003e \u003cp\u003e3.3 Enzyme-Based Amplified Electrochemical Aptasensors.\u003c\/p\u003e \u003cp\u003e3.4 Amplified Electrochemical Aptasensors Based on Nanoparticles.\u003c\/p\u003e \u003cp\u003e3.5 Label-Free Electrochemical Aptasensors.\u003c\/p\u003e \u003cp\u003e3.6 Field-Effect Transistor–Based Aptasensors.\u003c\/p\u003e \u003cp\u003e3.7 Conclusions and Perspectives.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 APTAMERS: HYBRIDS BETWEEN NATURE AND TECHNOLOGY\u003c\/b\u003e (\u003ci\u003eMoritz K. Beissenhirtz, Eik Leupold, Walter Stocklein, Ulla Wollenberger, Oliver Panke, Fred Lisdat, and Frieder W. Scheller\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 Specific Features of Aptamers.\u003c\/p\u003e \u003cp\u003e4.3 Electrochemical Detection of Nucleic Acids.\u003c\/p\u003e \u003cp\u003e4.4 Cytochrome \u003ci\u003ec\u003c\/i\u003e Binding by Aptamers.\u003c\/p\u003e \u003cp\u003e4.5 DNA Machines and Aptamers.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 DETECTION OF PROTEIN–APTAMER INTERACTIONS BY MEANS OF ELECTROCHEMICAL INDICATORS AND TRANSVERSE SHEAR MODE METHOD\u003c\/b\u003e (\u003ci\u003eTibor Hianik\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Immobilization of Aptamers on a Solid Support.\u003c\/p\u003e \u003cp\u003e5.3 Detection of Aptamer–Ligand Interactions.\u003c\/p\u003e \u003cp\u003e5.3.1 Electrochemical Methods.\u003c\/p\u003e \u003cp\u003e5.3.2 Acoustic Methods.\u003c\/p\u003e \u003cp\u003e5.4 Conclusions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 BIOSENSORS USING THE APTAMERIC ENZYME SUBUNIT: THE USE OF APTAMERS IN THE ALLOSTERIC CONTROL OF ENZYMES\u003c\/b\u003e (\u003ci\u003eKazunori Ikebukuro, Wataru Yoshida, and Koji Sode\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e6.1 Aptamers as Molecular Recognition Elements of Biosensors.\u003c\/p\u003e \u003cp\u003e6.1.1 Comparing Aptamers to Antibodies.\u003c\/p\u003e \u003cp\u003e6.1.2 Signaling Aptamers.\u003c\/p\u003e \u003cp\u003e6.2 Homogeneous Sensing.\u003c\/p\u003e \u003cp\u003e6.2.1 Biosensor Systems That Do Not Require Bound–Free Separation.\u003c\/p\u003e \u003cp\u003e6.2.2 Aptameric Enzyme Subunit.\u003c\/p\u003e \u003cp\u003e6.3 Evolution-mimicking Algorithm for the Improvement of Aptamers.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 NANOMATERIAL-BASED LABEL-FREE APTASENSORS\u003c\/b\u003e (\u003ci\u003eKagan Kerman and Eiichi Tamiya\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e7.1 Introduction.\u003c\/p\u003e \u003cp\u003e7.2 Label-Free Electrochemical Aptasensors.\u003c\/p\u003e \u003cp\u003e7.3 Field-Effect Transistor–Based Aptasensors.\u003c\/p\u003e \u003cp\u003e7.4 Label-Free Aptasensors Based on Localized Surface Plasmon Resonance.\u003c\/p\u003e \u003cp\u003e7.5 Forthcoming Challenges and Concluding Remarks.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 APTAMER-BASED BIOANALYTICAL ASSAYS: AMPLIFICATION STRATEGIES\u003c\/b\u003e (\u003ci\u003eSara Tombelli, Maria Minunni, and Marco Mascini\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e8.1 Introduction.\u003c\/p\u003e \u003cp\u003e8.2 Bioanalytical Assays Based on Aptamer-Functionalized Nanoparticles.\u003c\/p\u003e \u003cp\u003e8.3 Aptamers and Quantum Dot–Based Assays.\u003c\/p\u003e \u003cp\u003e8.4 Aptazymes and Aptamer-Based Machines.\u003c\/p\u003e \u003cp\u003e8.5 Polymerase Chain Reaction as an Amplification Method in Aptamer-Based Assays.\u003c\/p\u003e \u003cp\u003e8.6 Conclusions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIII APPLICATIONS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 KINETIC CAPILLARY ELECTROPHORESIS FOR SELECTION, CHARACTERIZATION, AND ANALYTICAL UTILIZATION OF APTAMERS\u003c\/b\u003e (\u003ci\u003eSergey N. Krylov\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e9.1 Introduction.\u003c\/p\u003e \u003cp\u003e9.1.1 Kinetic Capillary Electrophoresis.\u003c\/p\u003e \u003cp\u003e9.1.2 The Concept of NECEEM and ECEEM.\u003c\/p\u003e \u003cp\u003e9.2 Selection of Aptamers Using KCE Methods for Partitioning and Affinity Control.\u003c\/p\u003e \u003cp\u003e9.2.1 NECEEM-Based Selection of Aptamers.\u003c\/p\u003e \u003cp\u003e9.2.2 ECEEM-Based Selection of Aptamers.\u003c\/p\u003e \u003cp\u003e9.2.3 Optimization of PCR.\u003c\/p\u003e \u003cp\u003e9.2.4 Future of KCE Methods for Aptamer Selection.\u003c\/p\u003e \u003cp\u003e9.3 Measurements of Binding Parameters of Target–Aptamer Interaction by KCE Methods.\u003c\/p\u003e \u003cp\u003e9.3.1 Foundation.\u003c\/p\u003e \u003cp\u003e9.3.2 Temperature Control Inside the Capillary.\u003c\/p\u003e \u003cp\u003e9.3.3 Examples.\u003c\/p\u003e \u003cp\u003e9.4 Quantitative Affinity Analysis of a Target Using Aptamer as an Affinity Probe.\u003c\/p\u003e \u003cp\u003e9.4.1 Foundation.\u003c\/p\u003e \u003cp\u003e9.4.2 Example.\u003c\/p\u003e \u003cp\u003e9.5 Conclusions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 APTAMERS FOR SEPARATION OF ENANTIOMERS\u003c\/b\u003e (\u003ci\u003eCorinne Ravelet and Eric Peyrin\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e10.1 Introduction.\u003c\/p\u003e \u003cp\u003e10.2 Generation and Properties of Enantioselective Aptamers.\u003c\/p\u003e \u003cp\u003e10.3 Immobilized Aptamers for Enantiomeric Separation by Liquid Chromatography.\u003c\/p\u003e \u003cp\u003e10.3.1 Stationary-Phase Preparation and Column Packing.\u003c\/p\u003e \u003cp\u003e10.3.2 DNA Aptamer-Based CSPs.\u003c\/p\u003e \u003cp\u003e10.3.3 RNA Aptamer-Based CSPs and the Mirror-Image Strategy.\u003c\/p\u003e \u003cp\u003e10.3.4 Class-Specific Aptamer-Based CSPs.\u003c\/p\u003e \u003cp\u003e10.4 Aptamers for Analysis of Enantiomers by Capillary Electrophoresis.\u003c\/p\u003e \u003cp\u003e10.4.1 Aptamers as Chiral Additives in the Background Electrolyte for CE Enantiomeric Separation.\u003c\/p\u003e \u003cp\u003e10.4.2 Aptamers for the Design of an Affinity CE-Based Enantioselective Competitive Assay.\u003c\/p\u003e \u003cp\u003e10.5 Conclusions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 APTAMER-MODIFIED SURFACES FOR AFFINITY CAPTURE AND DETECTION OF PROTEINS IN CAPILLARY ELECTROPHORESIS AND MALDI–MASS SPECTROMETRY\u003c\/b\u003e (\u003ci\u003eLinda B. McGown\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e11.1 Introduction.\u003c\/p\u003e \u003cp\u003e11.2 Aptamer-Modified Capillaries in Affinity Capillary Electrophoresis.\u003c\/p\u003e \u003cp\u003e11.3 Aptamer-Modified Surfaces for Affinity MALDI-MS.\u003c\/p\u003e \u003cp\u003e11.3.1 Overview.\u003c\/p\u003e \u003cp\u003e11.3.2 Affinity MALDI-MS of Thrombin.\u003c\/p\u003e \u003cp\u003e11.3.3 Affinity MALDI-MS of IgE.\u003c\/p\u003e \u003cp\u003e11.3.4 Summary.\u003c\/p\u003e \u003cp\u003e11.4 Beyond Aptamers: Genome-Inspired DNA Binding Ligands.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 STRATEGY FOR USE OF SMART ROUTES TO PREPARE LABEL-FREE APTASENSORS FOR BIOASSAY USING DIFFERENT TECHNIQUES\u003c\/b\u003e (\u003ci\u003eBingling Li, Hui Wei, and Shaojun Dong\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e12.1 Introduction.\u003c\/p\u003e \u003cp\u003e12.2 Electrochemical Aptasensors.\u003c\/p\u003e \u003cp\u003e12.2.1 POSOALF Mode.\u003c\/p\u003e \u003cp\u003e12.2.2 PFSOALF Mode.\u003c\/p\u003e \u003cp\u003e12.2.3 Electrochemical Impedimetric Aptasensors.\u003c\/p\u003e \u003cp\u003e12.2.4 Electrochemical Aptasensors with Nonlabeled Redox Probes.\u003c\/p\u003e \u003cp\u003e12.3 Fluorescent Molecular Switches.\u003c\/p\u003e \u003cp\u003e12.3.1 POSFALF Mode.\u003c\/p\u003e \u003cp\u003e12.3.2 PFSFALF Mode.\u003c\/p\u003e \u003cp\u003e12.4 Colorimetry.\u003c\/p\u003e \u003cp\u003e12.4.1 POSFALF Mode.\u003c\/p\u003e \u003cp\u003e12.4.2 PFSFALF Mode.\u003c\/p\u003e \u003cp\u003e12.5 Hemin–Aptamer DNAzyme-Based Aptasensor.\u003c\/p\u003e \u003cp\u003e12.6 Liquid Chromatography, Electrochromatography, and Capillary Electrophoresis Applications.\u003c\/p\u003e \u003cp\u003e12.7 Other Aptasensors.\u003c\/p\u003e \u003cp\u003e12.8 Conclusions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eINDEX.\u003c\/b\u003e\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":52151099687255,"sku":"9780470148303","price":130.45,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470148303.jpg?v=1762960140","url":"https:\/\/bookcurl.com\/products\/aptamers-in-bioanalysis-9780470148303","provider":"Book Curl","version":"1.0","type":"link"}