{"product_id":"animal-experimentation-working-towards-a-paradigm-change-9789004356184","title":"Animal Experimentation: Working Towards a Paradigm Change","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eAnimal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eForeword   Peter Singer  Preface   Kathrin Herrmann and Kimberley Jayne  Acknowledgement  Notes on Contributors  Introduction   Kathrin Herrmann and Kimberley Jayne    Part 1: Why and How to Shift the Paradigm  1 Refinement on the Way Towards Replacement: Are We Doing What We Can?   Kathrin Herrmann  2 How to Evaluate the Science of Non-human Animal Use in Biomedical Research and Testing: A Proposed Format for Debate   Ray Greek and Lisa A. Kramer  3 How Can the Final Goal of Completely Replacing Animal Procedures Successfully be Achieved?   Christiane Baumgartl-Simons and Christiane Hohensee  4 Disease Prevention with a Plant-based Lifestyle   Sabina Vyas    Part 2: Politics and Legislation of Animal Experimentation  5 Political Campaigning: Where Scientific and Ethical Arguments Meet Public Policy   Emily McIvor  6 Rethinking the 3Rs: From Whitewashing to Rights   Charlotte E. Blattner  7 Contesting Animal Experiments through Ethics and Epistemology: In Defense of a Political Critique of Animal Experimentation   Arianna Ferrari    Part 3: Openness in Animal Experimentation  8 The Moral Status of Animal Research Subjects in Industry: A Stakeholder Analysis   Sarah Kenehan  9 Increasing the Transparency of Animal Experimentation: An Australian Perspective   Monika Merkes and Rob Buttrose  10 Wasted Money in United States Biomedical and Agricultural Animal Research   Jim Keen    Part 4: The Ethics and Philosophy of Animal Experimentation  11 Ethics, Efficacy, and Decision-making in Animal Research   Lawrence A. Hansen and Kori Ann Kosberg  12 Beyond Plausibility Checks: A Case for Moral Doubt in Review Processes of Animal Experimentation   Mara-Daria Cojocaru and Philipp von Gall  13 Human Wrongs in Animal Research: A Focus on Moral Injury and Reification   Jane Johnson and Anna Smajdor    Part 5: Effectiveness of the Animal Model  14 Critically Evaluating Animal Research   Andrew Knight  15 Extrapolation of Animal Research Data to Humans: An Analysis of the Evidence   Rebecca Ram  16 Is Animal-based Biomedical Research being Used in Its Original Context?   Constança Carvalho, Daniel Alves, Andrew Knight and Luis Vicente  17 The Scientific Problems with Using Non-human Animals to Predict Human Response to Drugs and Disease   Ray Greek and Lisa A. Kramer  18 Replacing Animal Tests to Improve Safety for Humans   Kathy Archibald, Robert Coleman and Tamara Drake  19 Genetic Modification of Animals: Scientific and Ethical Issues   Jarrod Bailey  20 Animal Research for Alzheimer Disease: Failures of Science and Ethics   John J. Pippin, Sarah E. Cavanaugh and Francesca Pistollato  21 Behavioral Research on Captive Animals: Scientific and Ethical Concerns   Kimberley Jayne and Adam See    Part 6: Animal-free Education and Training  22 Modernizing Biomedical Training: Replacing Live Animal Laboratories with Human Simulation   John Pawlowski, David Feinstein, Marie L. Crandall and Shalin Gala  23 Humane Education: The Tool for Scientific Revolution in Brazil   Vanessa Carli Bones, Rita de Cassia Maria Garcia, Gutemberg Gomes Alves, Rita Leal Paixão, Alexandro Aluísio Rocha, Karynn Capilé and Róber Bachinski    Part 7: The Paradigm Shift: Advanced Animal-free Approaches  24 Recent Developments in Alternatives to Animal Testing   Katy Taylor  25 The Changing Paradigm in Preclinical Toxicology: in vitro and in silico Methods in Liver Toxicity Evaluations   Fozia Noor  26 The Potential of Organ on Chip Technology for Replacing Animal Testing   Malcolm Wilkinson  27 When is an Alternative Not an Alternative? Supporting Progress for Absolute Replacement of Animals in Science   Craig Redmond  28 Research and Testing Without Animals: Where are We Now and Where are We Heading?   Thomas Hartung     Afterword: Evidence Over Interests   John P. Gluck   Index","brand":"Brill","offers":[{"title":"Default Title","offer_id":53210740785495,"sku":"9789004356184","price":164.8,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/animal-experimentation-working-towards-a-paradigm-change-9789004356184","provider":"Book Curl","version":"1.0","type":"link"}