{"product_id":"alpha-1-antitrypsin-deficiency-biologypathogenesisclinical-manifestationstherapy-88-lung-biology-in-health-and-disease-9780824788483","title":"Alpha 1  Antitrypsin Deficiency BiologyPathogenesisClinical ManifestationsTherapy 88 Lung Biology in Health and Disease","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eProviding a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of a1AT deficiency, describes the a1AT gene and its promoter, and details specific therapies to prevent the major clinical manifestations of the disorder.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eIntroduction \u003cbr\u003e\u003cbr\u003eAlpha 1-Antitrypsin Deficiency: An Introduction, Andrea Mastrangeli and Ronald G. Crystal\u003cbr\u003e\u003cbr\u003e\u003cbr\u003eBiology and Pathobiology \u003cbr\u003e\u003cbr\u003eAlpha 1-Antitrypsin Gene and Promoter, John G. Hay, Motoyoshi Suzuki, and Ronald G. Crystal\u003cbr\u003eAlpha 1-Antitrypsin Gene Evolution, Toshihiro Nukiwa, Fumitaka Ogushi, and Ronald G. Crystal\u003cbr\u003eAlpha 1-Antitrypsin Genotypes and Phenotypes, Mark Brantly\u003cbr\u003eStructure and Expression of the Human Neutrophil Elastase Gene, Kunihiko Yoshimura\u003cbr\u003eThe Three-Dimensional Structure of a1AT, Richard A. Engh and Wolfman Bode\u003cbr\u003eThe Three-Dimensional Structure of Human Neutrophil Elastase, Wolfram Bode\u003cbr\u003eKinetics of Neutrophil Elastase Inhibition In Vivo, Joseph G. Bieth\u003cbr\u003eAlpha 1-Antitrypsin Gene Expression in Neutrophils and Other Cells, Roland M. du Bois\u003cbr\u003eAlpha 1-Antitrypsin Gene Expression in Hepatocytes, Alfredo Nicosia and Paola Monaci\u003cbr\u003eAlpha 1-Antitrypsin Gene Expression in Mononuclear Phagocytes, Gregg Joslin and David H. Perlmutter\u003cbr\u003eTransgenic Animals with the a1AT Promoter, Wilfried Dalemans, Frédéric Perraud, Dalila Ali-Hadji, Sophie Jallat, and Andrea Pavirani\u003cbr\u003eChemistry and Biology of Secretory Leukoprotease Inhibitor, David F. Carmichael and Kjell Ohlsson \u003cbr\u003e\u003cbr\u003e\u003cbr\u003eClinical Manifestations \u003cbr\u003e\u003cbr\u003eLaboratory Diagnosis of a1AT Deficiency, Mark Brantly\u003cbr\u003eClinical Manifestations of a1AT Deficiency, Noel G. McElvaney and Ronald G. Crystal\u003cbr\u003eLung Function and a1AT Deficiency, Alan F. Barker, Ray G. D'silva, and A. Sonia Buist\u003cbr\u003eReactive Airways Disease and a1AT Deficiency, Robert J. Fallat\u003cbr\u003eNatural History of a1AT Deficiency, Janet Wittes and Margaret C. Wu\u003cbr\u003eThe Prevalence of a1AT Deficiency Outside the United States and Europe, Toshihiro Nukiwa, Kuniaki Seyama, and Shiro Kira\u003cbr\u003eThe National Institutes of Health National Heart, Lung and Blood Institute Registry for Patients with Severe Deficiency of Alpha 1-Antitrypsin, James K. Stoller \u003cbr\u003e\u003cbr\u003e\u003cbr\u003eTreatment \u003cbr\u003e\u003cbr\u003eTherapy of a1AT Deficiency, Noel G. McElvaney and Robert G. Crystal\u003cbr\u003eAugmentation of Liver Production, Mark D. Wewers\u003cbr\u003eLow-Molecular-Weight Inhibitors of Neutrophil Elastase, James C. Powers, R. Richard Plaskon, and Chih-Min Kam\u003cbr\u003ea1AT Deficiency and Liver Transplantation, David H. Van Thiel and Thomas E. Starzl\u003cbr\u003eLung Transplantation for a1AT Deficiency Emphysema, Elbert P. Trulock and Joel D. Cooper\u003c\/p\u003e","brand":"Taylor \u0026 Francis Inc","offers":[{"title":"Default Title","offer_id":52151194648919,"sku":"9780824788483","price":109.25,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780824788483.jpg?v=1762960404","url":"https:\/\/bookcurl.com\/products\/alpha-1-antitrypsin-deficiency-biologypathogenesisclinical-manifestationstherapy-88-lung-biology-in-health-and-disease-9780824788483","provider":"Book Curl","version":"1.0","type":"link"}