{"product_id":"a-guide-to-breast-cancer-research-9783031708749","title":"A Guide to Breast Cancer Research","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePart I: Development and cancer: basic concepts.- Chapter 1: Introductory chapter by Sorlie and Clarke.- Chapter 2: Embryonic mammary gland morphogenesis.- Chapter 3: Breast morphogenesis: from normal development to cancer.- Chapter 4: Single-Cell Analysis in the Mouse and Human Mammary Gland.- Part II: Development and cancer: model systems and approaches.- Chapter 5: Recording lineage history with cellular barcodes in the mammary epithelium and in breast cancer.- Chapter 6: Models for studying ductal carcinoma in situ progression.- Chapter 7: Patient-derived xenografts of breast cancer.- Chapter 8: Rat Models of Breast Cancer.- Part III: Development and cancer: cells of origin and heterogeneity.- Chapter 9: Cells of origin of breast cancer and intertumoral heterogeneity.- Chapter 10: Mechanisms of regulation of cell fate in breast development and cancer.- Chapter 11: Classification of breast cancer through the perspective of cell identity models.- Part IV:  Cellular and molecular basis.- Chapter 12: The Microenvironment in DCIS and its Role in Disease Progression.- Chapter 13: Molecular basis of breast tumor heterogeneity.- Chapter 14: E-cadherin-mediated cell-cell adhesion and invasive lobular breast cancer.- Part V: Signalling pathways.- Chapter 15: Hormone signaling in breast development and cancer.- Chapter 16: RANK\/RANKL signaling pathway in breast development and cancer.- Chapter 17: Metabolic Reprogramming and Adaption in Breast Cancer Progression and Metastasis.- Part VI: Metastasis and immunity.- Chapter 18: Microenvironmental regulation of dormancy in breast cancer metastasis: An ally that changes allegiances.- Chapter 19: The Roles of Myeloid Cells in Breast Cancer Progression.- Chapter 20: Immune microenvironment in breast cancer metastasis.- Part VII:  Subtypes, treatment and resistance.- Chapter 21: Clinical Implications of Breast Cancer Intrinsic Subtypes.- Chapter 22: Targeting Estrogen Receptor signalling in breast cancer therapy.- Chapter 23: CDK4\/6 inhibitor resistance in ER+ breast cancer.- Chapter 24: HER2-positive breast cancer treatment and resistance.\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Default Title","offer_id":51771992408407,"sku":"9783031708749","price":141.8,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783031708749.jpg?v=1758729843","url":"https:\/\/bookcurl.com\/products\/a-guide-to-breast-cancer-research-9783031708749","provider":"Book Curl","version":"1.0","type":"link"}