{"title":"Organic chemistry Books","description":"","products":[{"product_id":"stereoelectronic-effects-9780198558934","title":"Stereoelectronic Effects","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eEvery serious student of chemistry should try to develop a `feel'' for the way molecules behave - for the way they are put together and especially for the rules of engagement which operate when molecules meet and react. This primer describes how stereoelectronic effects control this behaviour. It is the only concise text on this topic at an undergraduate level. This is an important subject area and the comprehensive yet concise coverage in this book shows students how to build up a powerful but simple way of thinking about chemistry.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eThe subject is presented authoritatively, systematically and concisely without resort to mathematical treatment. As this subject is often given little coverage in textbooks or organic chemistry this text is to be welcomed. * Aslib Book Guide, vol.61, no.11, November 1996 *\u003cbr\u003eThis book is a useful introduction to stereo-electronic effects in organic chemistry. The style is engaging ... this book is an excellent supplementary text for undergraduates. Sponsorship for the series by Zeneca also ensures that it is extremely good value for money. * Chemistry in Britain, September 1997 *\u003cbr\u003eengaging critique of biography .... enjoyable and thought provoking * New Scientist *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction ; 1. The electronic basis of stereoelectronic effects ; 2. Effects on conformation ; 3. Effects on reactivity ; 4. Substitutions at saturated centres ; 5. Additions and eliminations ; 6. Rearrangements and fragmentations ; 7. Radical reactions","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732763160919,"sku":"9780198558934","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198558934.jpg?v=1719998294"},{"product_id":"how-to-succeed-in-organic-chemistry-9780198851295","title":"How to Succeed in Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e''How to succeed in organic chemistry'' gives the reader a solid understanding of the principles of organic reaction mechanisms, such that they can draw structures, stereoisomers and reaction mechanisms with confidence. Throughout, the author speaks the language of students to build their confidence and interest.At heart, the book promotes active learning to ensure the necessary skills become so ingrained that they become something students simply cannot forget, and do not need to revise. As such, the book structures learning so that the reader encounters the right things at the right time, helping to ''internalise'' key concepts.Concepts, explanations and examples are presented in short, easy-to-read chapters, each of which explores one of a number of themes, including ''Basics'', ''Habits'', ''Common error'', ''Reaction detail'', and ''Practice''.Digital formats and resources How to Succeed in Organic Chemistry is supported by online resources and is available for students and instit\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eI liked the slightly informal tone of writing, almost as if I was being taught one-to-one by the author. It felt personal and honest, as if the author wrote the book to help me personally. * Stephen Robertson, student, University of York *\u003cbr\u003eThis book would be a chemistry student's friend. It is different to any I have read before. There is a comforting level of informality, where you felt like your friend was going through and explaining things to you. * Yasmine Biddick, student, University of Birmingham *\u003cbr\u003eThis text represents a new way to teach organic chemistry and produce independent, critically thinking chemists; it acknowledges the connected world in which students live and utilises that to avoid the traditional endless lists of reactions for rote learning. Instead, this text focuses on the discipline and practice required by the novice and gives them the tools to become an expert. * Dr Jennifer Slaughter, Department of Chemistry, University of Manchester *\u003cbr\u003eThis is a unique textbook that does something no other text does - it speaks the language of the modern student and is formatted with that in mind. * Professor Mark Bagley, Department of Chemistry, University of Sussex *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSection 1: Laying the Foundations Basics 1: Structures of Organic Compounds Habit 1: Always Draw Structures with Realistic Geometry Basics 2: Functional Groups and \"R\" Groups Basics 3: Naming Organic Compounds Practice 1: Drawing Structures from Chemical Names Basics 4: Isomerism in Organic Chemistry - Constitutional Isomers Practice 2: Constitutional Isomers and Chemical Names Habit 2: Identifying When a Formula is Possible Practice 3: Double Bond Equivalents Common Error 1: Formulae, Functional Groups and Double Bond Equivalents Habit 3: Ignore What Doesn't Change Basics 5: Electronegativity, Bond Polarisation and Inductive Effects Practice 4: Bond Polarisation and Electronegativity Basics 6: Bonding in Organic Compounds Practice 5: Hybridisation Basics 7: Bonding and Antibonding Orbitals Basics 8: Introduction to Curly Arrows Fundamental Reaction Type 1: Nucleophilic Substitution at Saturated Carbon Practice 6: Electronegativity in Context Fundamental Reaction Type 2: Elimination Reactions Section 2: Building on the Foundations Basics 9: Breaking Bonds DS Linking Curly Arrows and Molecular Orbitals Common Error 2: Curly Arrows Basics 10: Conjugation and Resonance Basics 11: Thermodynamic Definitions Basics 12: Bond Dissociation Energy Basics 13: Calculating Enthalpy of Reaction from Bond Dissociation Energies Perspective 1: A Closer Look at Bond Dissociation Energies Practice 7: Calculating Enthalpy of Reaction from Bond Dissociation Energy Basics 14: Energetics and Reaction Profiles Basics 15: How Fast Are Reactions? Basics 16: Introduction to Carbocations, Carbanions and Free-Radicals Basics 17: Carbocations 2 - More Factors Affecting Stability Basics 18: Carbanions 2 - Stability and pKa Perspective 2: A Scale for Carbocation Stability Common Error 3: Methyl Groups are Electron-Releasing Practice 8: Drawing Resonance Forms for Carbocations and Carbanions Common Error 4: Resonance Basics 19: The Hammond Postulate Basics 20: Conjugation and Stability - The Evidence Common Error 5: Carbocations and Carbanions Basics 21: Reactivity of Conjugated Systems Basics 22: Acid Catalysis in Organic Reactions Part 1 Reaction Detail 1: Nucleophilic Substitution at Saturated Carbon Basics 23: What Defines a Transition State? Perspective 3: Bonding Beyond Hybridisation Fundamental Knowledge Recap 1: Bond Lengths and Strengths Fundamental Knowledge Recap 2: pKa Section 3: A Focus on Shape Habit 4: Representing Stereochemistry - Flying Wedge and Newman Projections Basics 23: Isomerism in Organic Chemistry - Configurational Isomers Habit 5: Getting Used to Drawing Stereoisomers Practice 9: Getting Used to Stereoisomers Habit 6: Assignment of Stereochemistry - The Cahn-Ingold-Prelog Rules Practice 10: Assigning Stereochemistry Habit 7: Stereoisomers with Symmetry Basics 25: Properties of Stereoisomers Reaction Detail 2: Stereochemical Aspects of Substitution Reactions Common Error 6: Substitution Reactions Reaction Detail 3: Substitution with Retention of Configuration Common Error 7: Stereochemical Errors Section 4: Types of Selectivity Basics 26: Selectivity in Organic Chemistry - Chemoselectivity Basics 27: Selectivity in Organic Chemistry - Regioselectivity Basics 28: Selectivity in Organic Chemistry - Stereoselectivity Basics 29: Stereochemical Definitions Relating to Reactions Section 5: Bonds Can Rotate Basics 30: Isomerism in Organic Chemistry - Conformational Isomers Practice 11: Conformational Analysis Applications 1: Conformational Isomers 2 Applications 2: SN2 Substitution Reactions Forming Three-Membered Rings Basics 31: Introduction to Cyclohexanes Practice 12: Drawing Cyclohexanes Applications 3: Substitution Reactions of Cyclohexanes Basics 32: Quantifying Conformers of Cyclohexanes Basics 33: More Conformers of Cyclohexanes and Related Compounds Practice 13: Drawing More Complex Cyclohexanes Common Error 8: Cyclohexanes Section 6: Eliminating the Learning Reaction Detail 4: Elimination Reactions Perspective 4: A Continuum of Mechanisms Basics 34: More Substituted Alkenes Are More Stable Basics 35: Enthalpy Changes for Reactions Involving Anionic Species Applications 4: Stereochemistry of Elimination Reactions Basics 36: Stereospecificity Applications 5: Elimination Reactions of Cyclohexanes Common Error 9: Elimination Reaction Reaction Detail 5: Allylic Substitution Section 7: Building Skills Worked Problem 1: Curly Arrows and Reaction Profiles Worked Problem 2: Competing SN1 Substitution and E1 Elimination Worked Problem 3: Competing SN2 Substitution and E2 Elimination Worked Problem 4: Acid Catalysis in Organic Reactions Part 2 Worked Problem 5: Epoxide Opening Reactions Worked Problem 6: Is cis-Cyclohexane-1,2-diol Really Achiral? Worked Problem 7: The Furst-Plattner Rule Worked Problem 8: SN2' Stereochemistry and Conformations Worked Problem 9: Complex Substitution Stereochemistry Worked Problem 10: Cyclisation Reactions Solution to Problem 1: Curly Arrows and Reaction Profiles Solution to Problem 2: Competing SN1 Substitution and E1 Elimination Solution to Problem 3: Competing SN2 Substitution and E2 Elimination Solution to Problem 4: Acid Catalysis in Organic Reactions Part 2 Solution to Problem 5: Epoxide Opening Reactions Solution to Problem 6: Is cis-Cyclohexane-1,2-diol Really Achiral? Solution to Problem 7: The Furst-Plattner Rule Solution to Problem 8: SN2' Stereochemistry and Conformations Solution to Problem 9: Complex Substitution Stereochemistry Solution to Problem 10: Cyclisation Reactions","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732812869975,"sku":"9780198851295","price":31.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198851295.jpg?v=1719998506"},{"product_id":"why-chemical-reactions-happen-9780199249732","title":"Why Chemical Reactions Happen","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eBy tackling the most central ideas in chemistry, Why Chemical Reactions Happen provides the reader with all the tools and concepts needed to think like a chemist. The text takes a unified approach to the subject, aiming to help the reader develop a real overview of chemical processes, by avoiding the traditional divisions of physical, inorganic and organic chemistry. To understand how chemical reactions happen we need to know about the bonding in molecules, how molecules interact, what determines whether an interaction is favourable or not, and what the outcome will be. Answering these questions requires an understanding of topics from quantum mechanics, through thermodynamics, to curly arrows. In this book all of these topics are presented in a coherent and coordinated fashion, showing how each leads to a deeper understanding of chemical reactions.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eI feel that Peter and James have done a tremendous job of explaining chemical reactions using perspectives that are not used in traditional text books. They explain reactions in terms of bonding theories and orbitals rather than solely using kinetics and equilibrium. The author's use of visual representations throughout the book increases the comprehension of the material covered in the text. I look forward to using this textbook in my organic chemistry courses. Physical Sciences Educational Reviews 2004.\u003cbr\u003e'Why Chemical Reactions Happen is one of nature's secrets....This insightful book reveals in clear and impressive style what motivates molecules to metamorphose into something new. It supplies all the essentials for understanding entrophy and how to choreograph molecular transformations to its music' Times Higher Education Supplement, February 2004.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. What this book is about and who should read it ; 2. What makes a reaction go? ; 3. Ionic interactions ; 4. Electrons in atoms ; 5. Electrons in simple molecules ; 6. Electrons in larger molecules ; 7. Reactions ; 8. Equilibrium ; 9. Rates of reaction ; 10. Bonding in extended systems - conjugation ; 11. Substitution and elimination reactions ; 12. The effects of the solvent ; 13. Leaving groups ; 14. Competing reactions","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732838396247,"sku":"9780199249732","price":36.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199249732.jpg?v=1719998617"},{"product_id":"chemical-structure-and-reactivity-an-integrated-approach-9780199604135","title":"Chemical Structure and Reactivity An Integrated","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWhy do certain substances react together in the way that they do? What determines the shape of molecules? And how can we predict whether a particular reaction will happen at all?Such questions lie at the heart of chemistry - the science of understanding the composition of substances, their reactions, and properties. While often fragmented into the strands of inorganic, organic, and physical chemistry, a full understanding of chemistry can only be gained by seeing the subject as a single, unified whole.Chemical Structure and Reactivity rises to the challenge of depicting the reality of chemistry. Offering a fresh approach to undergraduate teaching, it depicts the subject as a seamless discipline, showing how organic, inorganic, and physical concepts can be blended together to achieve the common goal of understanding chemical systems.With a lively and engaging writing style augmented throughout by purpose-drawn illustrations, and custom-developed online support, Chemical Structure and Reactivity alone makes taking an integrated approach in the teaching of chemistry a realistic proposition.Online Resources:For students: Custom developed multimedia content linked to the book, enabling students to investigate the concepts and phenomena presented in the book in a fully interactive way. Question sets to help students master concepts and gain confidence through hands-on engagement.For lecturers: Fully worked solutions to the exercises available through the Online Resource Centre.For registered adopters of the book: Figures from the book in electronic format.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition This is the most innovative and impressive undergraduate chemistry textbook I have been exposed to in years; it is quite outstanding in its creative and imaginative approach.    The authors appear to have stood back and re-thought the whole approach to teaching chemistry at this level. The logical and innovative order in which material is developed and explained is all the more impressive when we take account of the fact that rigour and attention to detail is not compromised. * Dr David McGarvey, Keele University *\u003cbr\u003eThe objective of the authors, to break down the barriers used to manage the teaching of chemistry, is laudable, and they achieve their aim, particularly in the first section of the book. They have assembled a teaching resource that is refreshing in its style and rigorous in its content. * Education in Chemistry, 2009 *\u003cbr\u003eIt is a tremendous contribution to the teaching of the chemical sciences. The authors have adopted a new approach to the teaching of chemistry which cuts through physical, inorganic and organic chemistry as needed. This text is brilliant for students who want a book that explains difficult concepts in an accessible but still rigorous form. * Dr M. Crispin, Oriel College, Oxford *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePART I: THE FUNDAMENTALS; PART II: GOING FURTHER","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732872737111,"sku":"9780199604135","price":65.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199604135.jpg?v=1719998759"},{"product_id":"pericyclic-reactions-9780199680900","title":"Pericyclic Reactions","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe renowned Oxford Chemistry Primer series, which provides focused introductions to a range of important topics in chemistry, has been refreshed and updated to suit the needs of today''s students, lecturers, and postgraduate researchers. The rigorous, yet accessible, treatment of each subject area is ideal for those wanting a primer in a given topic to prepare them for more advanced study or research. Moreover, cutting-edge examples and applications throughout the texts show the relevance of the chemistry being described to current research and industry. Learning features provided in the primers, including questions at the end of every chapter and interactive online MCQs, encourage active learning and promote understanding. Furthermore, frequent diagrams, margin notes, further reading, and glossary definitions all help to enhance a student''s understanding of these essential areas of chemistry.Pericyclic reactions constitute a major strand of organic chemistry, including such commerci\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. The nature of pericyclic reactions ; 2. Cycloaddition reactions ; 3. The Woodward-Hoffmann rules and molecular orbitals ; 4. Electrocyclic reactions ; 5. Sigmatropic rearrangements ; 6. Group transfer reactions","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732882534743,"sku":"9780199680900","price":31.99,"currency_code":"GBP","in_stock":true}]},{"product_id":"organic-chemistry-a-mechanistic-approach-9780199693276","title":"Organic Chemistry A mechanistic approach","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOrganic Chemistry: A mechanistic approach provides readers with a concise review of the essential concepts underpinning the subject. It combines a focus on core topics and themes with a mechanistic approach to the explanation of the reactions it describes, making it ideal for those looking for a solid understanding of the central themes of organic chemistry.Opening with a review of chemical bonding and molecular shape and structure, the book then introduces the principal groups of organic compound before exploring the range of reactions they undergo. It retains an emphasis throughout on how and why organic compounds behave in the way they do, with a chapter on how mechanisms are investigated and the closing chapter describing the principal methods by which the structure and composition of organic compounds are studied.  With an understanding of organic chemistry being central to the study and practice of a range of disciplines, Organic Chemistry is the ideal resource for those studying\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eThe structure and aim of the text is excellent. [It] begins with the fundamentals of molecular structure and introduces the concept of molecular orbitals early... it clearly maintains a direct link to understanding reaction mechanisms from their fundamental origins. * Chemistry World, July 2014 *\u003cbr\u003eI will definitely recommend this book to other people. The book not only contains the correct way of doing things but also highlights the incorrect ways or any common mistakes to avoid, which is also absent in most other textbooks. This is much like a tutor tutoring us instead of just reading a book with facts. * Shuang Liu, student, Imperial College London *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Chemical bonding and molecules ; 2. Molecular structure and shapes of organic molecules ; 3. Organic compounds: their functional groups, intermolecular interactions and physical properties ; 4. Conformation and strain in molecules ; 5. Conjugation, pi-electrion delocalization, and aromaticity ; 6. Acids and bases ; 7. Organic reactions and concept of mechanism ; 8. Nucleophilic addition to the carbonyl group in aldehydes and ketones ; 9. Nucleophilic substitution of carboxylic acid derivatives ; 10. Reactions of carbonyl compounds with hydride donors and organometallic reagents ; 11. Stereochemistry and molecular chirality ; 12. Nucleophilic substitution reactions of haloalkanes and related compounds ; 13. Elimination reactions of haloalkanes and related compounds ; 14. Reactions of alcohols, ethers, thiols, sulfides, and amines ; 15. Addition reactions of alkenes and alkynes ; 16. Enolate anions and their reactions ; 17. Enolate ions, their equivalents and reactions ; 18. Reactions of nucleophiles with alkenes and aromatic compounds ; 19. Polycyclic and heterocyclic aromatic compounds ; 20. Rearrangement reactions ; 21. Pericyclic reactions: cycloadditions, electrocyclic reactions, and sigmatropic rearrangements ; 22. Rearrangement reactions involving polar molecules and ions ; 23. Biomolecules ; 24. Chemistry of biomolecules ; 25. Structural determination of organic compounds","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732887777623,"sku":"9780199693276","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"instrumental-analytical-chemistry-9781032205823","title":"Instrumental Analytical Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book includes the fundamental principles, techniques, applications, and descriptions of instrumentation. The scope of the book covers just what is needed for an undergraduate course and is suitable for non chemistry majors. Extensive references for further research on the topic is included.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eChapter 01\u003c\/p\u003e\u003cp\u003eConcepts of Instrumental Analytical Chemistry\u003c\/p\u003e\u003cp\u003eChapter 02\u003c\/p\u003e\u003cp\u003eIntroduction to Spectroscopy\u003c\/p\u003e\u003cp\u003eChapter 03\u003c\/p\u003e\u003cp\u003eVisible and Ultraviolet Molecular Spectroscopy\u003c\/p\u003e\u003cp\u003eChapter 04\u003c\/p\u003e\u003cp\u003eInfrared, Near-Infrared, and Raman Spectroscopy\u003c\/p\u003e\u003cp\u003eChapter 05\u003c\/p\u003e\u003cp\u003eMagnetic Resonance Spectroscopy\u003c\/p\u003e\u003cp\u003eChapter 06\u003c\/p\u003e\u003cp\u003eAtomic Absorption Spectrometry\u003c\/p\u003e\u003cp\u003eChapter 07\u003c\/p\u003e\u003cp\u003eAtomic Emission Spectroscopy\u003c\/p\u003e\u003cp\u003eChapter 08\u003c\/p\u003e\u003cp\u003eX-Ray Spectroscopy\u003c\/p\u003e\u003cp\u003eChapter 09\u003c\/p\u003e\u003cp\u003eMass Spectrometry \u003c\/p\u003e\u003cp\u003eChapter 10\u003c\/p\u003e\u003cp\u003ePrinciples of Chromatography\u003c\/p\u003e\u003cp\u003eChapter 11\u003c\/p\u003e\u003cp\u003eGas Chromatography\u003c\/p\u003e\u003cp\u003eChapter 12\u003c\/p\u003e\u003cp\u003eChromatography with Liquid Mobile Phases\u003c\/p\u003e\u003cp\u003eChapter 13\u003c\/p\u003e\u003cp\u003eElectroanalytical Chemistry\u003c\/p\u003e\u003cp\u003eChapter 14\u003c\/p\u003e\u003cp\u003eThermal Analysis\u003c\/p\u003e","brand":"Taylor \u0026 Francis Ltd","offers":[{"title":"Default Title","offer_id":48738043035991,"sku":"9781032205823","price":29.99,"currency_code":"GBP","in_stock":true}]},{"product_id":"biocatalysis-in-organic-synthesis-the-retrosynthesis-approach-9781782625308","title":"Biocatalysis in Organic Synthesis: The","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe application of biocatalysis in organic synthesis is rapidly gaining popularity amongst chemists. Compared to traditional synthetic methodologies biocatalysis offers a number of advantages in terms of enhanced selectivity (chemo-, regio-, stereo-), reduced environmental impact and lower cost of starting materials. Together these advantages can contribute to more sustainable manufacturing processes across a wide range of industries ranging from pharmaceuticals to biofuels. The biocatalytic toolbox has expanded significantly in the past five years and given the current rate of development of new engineered biocatalysts it is likely that the number of available biocatalysts will double in the next few years.  This textbook gives a comprehensive overview of the current biocatalytic toolbox and also establishes new guidelines or rules for “biocatalytic retrosynthesis”. Retrosynthesis is a well known and commonly used technique whereby organic chemists start with the structure of their target molecule and generate potential starting materials and intermediates through a series of retrosynthetic disconnections. These disconnections are then used to devise a forward synthesis, in this case using biocatalytic transformations in some of the key steps. Target molecules are disconnected with consideration for applying biocatalysts, as well as chemical reagents and chemocatalysts, in the forward synthesis direction. Using this textbook, students will be able to place biocatalysis within the context of other synthetic transformations that they have learned earlier in their studies. This additional awareness of biocatalysis will equip students for the modern world of organic synthesis where biocatalysts play an increasingly important role. In addition to guidelines for identifying where biocatalysts can be applied in organic synthesis, this textbook also provides examples of current applications of biocatalysis using worked examples and case studies. Tutorials enable the reader to practice disconnecting target molecules to find the ‘hidden’ biocatalytic reactions which can be applied in the synthetic direction. The book contains a complete description of the current biocatalyst classes that are available for use and also suggests areas where new enzymes are likely to be developed in the next few years. This textbook is an essential resource for lecturers and students studying synthetic organic chemistry. It also serves as a handy reference for practicing chemists who wish to embed biocatalysis into their synthetic toolbox.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction and Aims of the Book; Biocatalysis Basics and Principles; Hydrolysis; Reverse Hydrolysis: Reduction; Oxidation; C–X Bond Formation; C–C Bond Formation, Miscellaneous Biocatalysts; Biocatalytic Disconnections and Functional Group Interconversions; Comparison of Different Biocatalytic Routes to Target Molecules; Applications of Biocatalytic Retrosynthesis","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741113921879,"sku":"9781782625308","price":47.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781782625308.jpg?v=1720056617"},{"product_id":"chromic-phenomena-technological-applications-of-colour-chemistry-9781782628156","title":"Chromic Phenomena: Technological Applications of","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eChromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments.   In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart 1 Colour Change Phenomena and their Applications - Introduction; Photochromism; Thermochromism; Ionochromism: Halochromism, Acidochromism and Metallochromism; Electrochromism; Gasochromism; Solvatochromism; Vapochromism; Mechanochromism; Chromic Phenomena via Aggregation; Miscellaneous Chromisms; Colour Change and Nanoplasmonics; Electrophoretic Displays; Part 2 Luminescent Materials and their Applications - Introduction; Photochromism; Chemiluminescence; Bioluminescence; Electrochemiluminescence; Electroluminescence; Mechanoluminescence; Incandescence; Part 3 Light Processing Materials in Biomedical, Energy and Other Applications - Introduction; Near-Infrared Absorbers and Their Applications; Optical Data Storage; Organic Photoconductors; Photosensitisers; Photosensitisers in Medicine and Chemical Biology; Solar Energy Utilisation; Conversion of Light into Kinetic Energy; Part 4 Light Manipulation Materials, Structural Colours and Photonics; Introduction; Liquid Crystal Materials and Their Uses; Colours from Physical Effects; Holography; Laser Diodes; Nonlinear Optics; Photorefractive Polymers; Organic Chromophores used as Commercial Dyes and Pigments; Increase in the Number of Relevant Scientific Publications; Subject Index","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741114052951,"sku":"9781782628156","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"the-chemical-story-of-olive-oil-from-grove-to-table-9781782628569","title":"The Chemical Story of Olive Oil: From Grove to","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eDespite the growing interest in olive oil, most people know very little about what it is or how it is made. This book provides a comprehensive treatment of olive oil from the tree to table, from a molecular and personal perspective.   Growers often do not know what is happening at a molecular level or why certain practices produce superior or inferior results, for example, why adjusting a temperature rewards them with winning oils. This book aims to provide some of the answers as well as the importance of the chemicals responsible for the flavour and health effects. Readers will also get a deeper understanding of what makes an extra virgin olive oil authentic and how scientists are helping to fight fraud regarding this valuable commodity.   Including anecdotes from growers of olives and producers of oils, the authors provide an accessible text for a wide audience from food science students to readers interested in the human story of olive oil production.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eOlive Origins; The Beginning of a Grove: Planting the Trees; The Tree Through the Year; Season's End: Harvesting the Fruit; Processing: The Most Important Hour; Delivering Quality and Assuring Authenticity; Good Taste is Required; Health Effects: But is Olive Oil Good for You?; 1001 Uses for Olive Oil; Sustainability","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741114118487,"sku":"9781782628569","price":28.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781782628569.jpg?v=1720056618"},{"product_id":"caesars-last-breath-the-epic-story-of-the-air-around-us-9781784162931","title":"Caesar's Last Breath: The Epic Story of The Air","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003e** GUARDIAN SCIENCE BOOK OF THE YEAR 2017 **\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e‘Popular science at its best’\u003cbr\u003e\u003ci\u003eMail on Sunday\u003cbr\u003e\u003c\/i\u003e\u003cbr\u003e‘Eminently accessible and enjoyable’\u003cbr\u003e\u003ci\u003eObserver\u003c\/i\u003e\u003cbr\u003e\u003cbr\u003eWith every breath, you literally inhale the history of the world. On the ides of March, 44 BC, Julius Caesar died of stab wounds in the Roman Senate, but the story of his last breath is still unfolding. In fact, you're probably inhaling some of it now. Of the sextillions of molecules entering or leaving your lungs at this moment, some might also bear traces of Cleopatra's perfumes, German mustard gas, particles exhaled by dinosaurs or emitted by atomic bombs, even remnants of stardust from the universe's creation. \u003cbr\u003e\u003cbr\u003eIn \u003ci\u003eCaesar’s Last Breath\u003c\/i\u003e, \u003ci\u003eNew York Times\u003c\/i\u003e bestselling author Sam Kean takes us on a journey through the periodic table, around the globe and across time to tell the epic story of the air we breathe.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eAbsorbing, entertaining... provocative but compelling... eminently accessible and enjoyable. A real gas - in short!\u003c\/b\u003e -- Robin McKie * Observer *\u003cbr\u003e\u003cb\u003eFunny, clever and altogether effervescent... Kean writes superbly about science itself... A joy for any reader\u003c\/b\u003e -- James McConnachie * The Sunday Times *\u003cbr\u003e\u003cb\u003eThere is no denying the pleasure and indeed the wealth of scientific information to be obtained from reading Caesar’s Last Breath. It will change forever the way I think about breathing.\u003c\/b\u003e * Financial Times *\u003cbr\u003e\u003cb\u003eKean is the teacher you wish you'd had: genial, companionable and infectiously enthusiastic. This is an entertaining and accessible guide to the mysterious vapour of gases. Popular science at its best.\u003c\/b\u003e -- Simon Humphreys * Mail on Sunday *\u003cbr\u003e\u003cb\u003eIt’s a helluva read. And it’s a gas.\u003c\/b\u003e -- Tim Radford * The Guardian *\u003cbr\u003e\u003cb\u003e\u003ci\u003eAn altogether excellent read, an invigorating and stylish mixture of chemistry, history and reportage that brings to light many of the untold stories of the air that surrounds and sustains us\u003c\/i\u003e\u003c\/b\u003e * Times Literary Supplement *\u003cbr\u003e\u003cb\u003eThis vibrant, fact-filled science book makes the chemistry of air riveting\u003c\/b\u003e * Sunday Times Must Reads *\u003cbr\u003e\u003cb\u003eTold with Kean’s trademark combination of goofy wisecracking and an exceptional knack for communicating the principles of science\u003c\/b\u003e * Wall Street Journal *\u003cbr\u003e\u003cb\u003eFascinating stories, so insightful, informative, and disarmingly written. It gave this astronaut a new respect for the air around us all, and made me delightfully more aware of each breath I take.\u003c\/b\u003e -- Col. Chris Hadfield, author of An Astronaut's Guide to Life on Earth\u003cbr\u003e\u003cb\u003eBrims with such fascinating tales of chemical history that it'll change the very way you think about breathing.... Kean crams the book full of wild yarns told with humorously dramatic flair.... The effect is oddly intimate, the way all good storytelling is -- you feel like you're sharing moments of geeky amusement with a particularly hip chemistry teacher\u003c\/b\u003e * San Francisco Chronicle *\u003cbr\u003e\u003cb\u003eThe most fun to be had from nonfiction is a good science book, with a writer of craft who can capture both the excitement and the elegance of science, the incredible fact that this is really how it works. Sam Kean is such a writer and \u003ci\u003eCaesar's Last Breath\u003c\/i\u003e is such a book. An enormous pleasure to read.\u003c\/b\u003e -- Mark Kurlansky, author of Cod\u003cbr\u003e\u003cb\u003eSam Kean has done it again - this time clearly and entertainingly explaining the science of the air around us. He is a gifted storyteller with a knack for finding the magic hidden in the everyday.\u003c\/b\u003e -- Daniel H. Pink, author of Drive","brand":"Transworld Publishers Ltd","offers":[{"title":"Default Title","offer_id":48741206393175,"sku":"9781784162931","price":9.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781784162931.jpg?v=1720056898"},{"product_id":"nitroxides-synthesis-properties-and-applications-9781788017527","title":"Nitroxides: Synthesis, Properties and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eNitroxides are versatile small organic molecules possessing a stabilised free radical. With their unpaired electron spin they display a unique reactivity towards various environmental factors, enabling a diverse range of applications. They have uses as synthetic tools, such as catalysts or building blocks; imaging agents and probes in biomedicine and materials science; for medicinal antioxidant applications; and in energy storage. Polynitroxides (polymers bearing pendant nitroxide sidechains) have been used in organic radical batteries, oxidation catalysts and in exchange reactions for constructing complex architectures. Chapters in this book cover the synthesis of nitroxides, EPR studies and magnetic resonance applications, physiochemical studies, and applications including in batteries, imaging and organic synthesis. With contributions from leaders in the field, Nitroxides will be of interest to graduate students and researchers across chemistry, physics, biology and materials science.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eA Brief History and Outlook of Nitroxides; General Approaches to Synthesis of Nitroxides; The Application of Nitroxides in Organic Synthesis; Sprin Probes and Imaging Using Nitroxides; Nitroxides in Battery-related Applications; Computational Tools for Nitroxide Design; Nitroxide-mediated Polymerization; Nitroxides in Supramolecular Chemistry; Magnetism of Nitroxides; Applications of Nitroxide Spin Labels to Structural Biology; Nitroxides in Liquid Crystals; Nitroxide Intervention in Oxidative and Free Radical Damage in Biology and Disease; Spin Trapping; Biological Applications of Nitroxide Stable Free Radicals; Introduction to Electron Paramagnetic Resonance (EPR) of Nitroxides","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741569266007,"sku":"9781788017527","price":170.05,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781788017527.jpg?v=1720057997"},{"product_id":"perfume-in-the-bible-9781788017305","title":"Perfume in the Bible","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003ePerfume is part of the biblical text from Genesis through to Revelation, just as perfume pervades our modern life. Identifying the ingredients used in biblical times is difficult when information and meaning is lost in ancient languages. As expected, biblical perfumes were made from natural products but the range employed is surprisingly different from those of modern perfumes. The biblical ingredients are either defensive substances or products of decay, opening up an avenue of speculation as to why this is so.   Charles Sell started his research into this area whilst working at Givaudan, the world’s leading manufacturer of perfumes and flavours. The introductory chapter of this book gives a brief outline of the history of the Bible lands, paving the way to understanding the difficulties in identifying exactly which plant sources the original authors meant. Other chapters discuss how plants make chemicals and how the sense of smell functions. The book explores the preparation, storage and uses of perfume, both sacred and secular, and compares and contrasts biblical perfumes with their modern equivalents. It recounts some interesting biblical events involving perfume ranging from courtship through seduction to prostitution and murder. The use of beautiful images from the windows of Canterbury Cathedral, where the author is a guide, illustrate some of the people and events in the biblical accounts and enable visualization of the historical uses of perfumes.   The book is aimed at a broad audience and requires no prior specialised knowledge. The subject matter will be of interest to everyone, including chemists and general scientists, historians, those interested in perfumery, those interested in religious studies, and anyone interested in exploring chemistry in the world of art and the creative professions.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eIt is a wide-ranging study in which, in addition to chemistry, Dr Sell examines geographical sources, botany, sensory science, medicine, and the arts. There is even a section on perfume storage. Bottles, interestingly, have survived from before 500 BC, and Isaiah mentions the ownership of perfume bottles as one of the trappings of wealth, along with bracelets, charms, and nose-rings. -- Ted Harrison * The Church Times *\u003cbr\u003eIt's amazing how often the subject of smell comes up in the Bible, whether it be pleasing odours of sacrifice of Noah or the perfumes of the Song of Songs - and of course that expensive perfume used to anoint Jesus's feet, much to Judas's horror. Dr. Sell takes us on a fascinating journey through both Bible and science, laying bare the mechanism of smell and then seeking to explain how these perfumes (all natural ingredients in those days) were obtained. The evidence is often fragmentary (let's face it, the Bible was never meant to be an instruction in the art of perfume formulation), but Dr. Sell teases out many fascinating details, and augments them with beautiful illustrations using the stained glass windows, particularly those of Canterbury cathedral. A must for anyone interested in perfumery or chemistry. -- Teemacs * Amazon Review *\u003cbr\u003eTed Harrison follows his nose through the Bible Christianity can be an olfactory faith. Low Church Protestantism might smell rather bland; but the further the worshipper moves towards the Catholic end of the spectrum, the more the nose is assaulted and delighted. Smell plays an important part in the biblical narrative, from the aromas of burnt offerings in the Old Testament through to the precious perfume used shortly before the Passion to anoint Christ. From Genesis 2 to Revelation 18 there are more than 200 references to perfume, odour, and smell. The old Temple in Jerusalem must have produced an over-powering stench of sweaty humans, frightened animals, burning flesh, and incense. The scene of the resurrection must have had a distinctive smell of embalming chemicals mixed with the early morning scents of garden plants. About 12 years ago, Dr Charles Sell, a chemist who was then working for an industrial fragrance company in Kent, started a research project into the history and chemistry of the biblical references. The results of his work have now been published as a book by the Royal Society of Chemistry, Perfumes in the Bible (pubs.rsc.org). It is a wide-ranging study in which, in addition to chemistry, Dr Sell examines geographical sources, botany, sensory science, medicine, and the arts. There is even a section on perfume storage. Bottles, interestingly, have survived from before 500 BC, and Isaiah mentions the ownership of perfume bottles as one of the trappings of wealth, along with bracelets, charms, and nose-rings. Some of the substances referred to in Perfumes in the Bible are familiar. Frankincense and myrrh are central to the nativity story as two of the gifts of the magi. Yet there were also many rare and exotic scents available to the people of the ancient world, with names that are no longer instantly recognised, such as onycha, galbanum, styrax, and nard. Matching the original Hebrew and Greek to modern names was not, Dr Sell found, always a matter of straightforward translation, and required additional linguistic research. The story starts with the mention of the river flowing from the Garden of Eden. One branch led to the land of Havilah, where, as well as gold and precious stones, bdellium was to be found, a fragrant gum resin and an early ingredient of perfume. For many centuries — until science devised ways of analysing the chemical make-up of smells — the perfumers’ practice was a secretive art. Formulae were rarely published. When Herodotus asked the perfumers of Arabia where they found labdanum, they told him a cock-and-bull story about how they combed it from the beards of goats. Given such reticence, it comes as a surprise to find two recipes set out in the book of Exodus. They were protected not by secrecy, but by threat of punishment: those who tried to recreate sacred tabernacle perfumes for their own use would be sent into exile. Measured out in shekels, the Lord told Moses to take portions of myrrh, cinnamon, calamus, and orris, and, having dissolved them in olive oil, to use the mixture to anoint all the holy vessels as sacred, and to anoint Aaron and his sons as priests. The sacred incense was to contain equal amounts of styrax, onycha, galbanum, and frankincense, ground together into a fine powder. On the Day of Atonement, Aaron was to burn clouds of incense to obscure the Ark of the Covenant to protect him from seeing God. Strict instructions were given that only the priests were to use the special holy incense, and, when 250 men disobeyed the command, they were destroyed by divine fire, the book of Numbers relates. The ancient world of the Middle East was the centre of a network of trade routes that enabled aromatic ingredients to be sourced from many hundreds of miles away. Frankincense, according to Jeremiah, was brought from Sheba, and is today produced in the Horn of Africa and the south-west tip of the Arabian peninsula. Of all fragrances that get a mentionb only galbanum, a resin extracted from a flowering umbelliferous plant, is a true native of the Bible lands. Cinnamon comes from Sri Lanka, and cassia and agarwood are products of China. Frankincense is collected as “tears”: nuggets of a pale-yellow resin that oozes from wounds cut in the incense tree, one of the Burseraceae family. As with many types of tree, when the bark is damaged nature responds by producing a chemical to protect the tree from bacterial and fungal attack. The chemical solidifies to form a substance that exudes a fragrant smoke when burned. Myrrh is also sourced from Burseraceae trees, in the same regions of the world as frankincense. The antimicrobial chemicals produced by the trees to protect themselves have properties that can also be used in the embalming of bodies. Nard, or spikenard comes from much further afield. It is extracted from the roots of a shrub growing at high altitude in the Himalayas. It formed the highly expensive perfume used by the woman, probably Mary Magdalene, who anointed Christ’s feet and dried them with her hair, in St John’s account. The perfume’s cost can be attributed to both its rarity and the distance it had to travel. Exactly how valuable it was became a matter of some debate in the Gospels, and the quantity used by Mary was probably worth the equivalent of a year’s wages. What a waste, the disciples said — the perfume should have been sold, and the money given to the poor. But Jesus rebuked them, telling them: “It was intended that she should save this perfume for the day of my burial.” Perfume in the Bible is found in prophecy, metaphor, and poetry. The gifts of the magi — gold, frankincense and myrrh — served a prophetic purpose as they foretold Christ’s kingship, priesthood and death. St Paul employs metaphorical references to perfume in his Epistles. In writing to the Corinthians, he talks of sharing the good news of Jesus as spreading the pleasing aroma of Christ. And the Ephesians are told that followers of Christ should be an offering whose fragrance is pleasing to God. Poetry, however, provides the richest vein of references. In the Song of Songs, the celebrated book of erotic love, the bride says of her bridegroom: “Fragrant is the scent of your perfume and your name like perfume poured out. While the king was at his table, my perfume spread its fragrance. My beloved is to me a sachet of myrrh resting between my breasts.” Psalm 45 is one of several employing the language of fragrance (“All your robes are fragrant with myrrh and aloes and cassia”). In Psalm 141, prayers are likened to incense. The sense of smell is one of the oldest in animal evolution. And, even if it is not the prime sense for humans, it remains one of great potency. As the Bible writers knew well, smell has a powerful effect on the emotions. Smell evokes memories and, in the right circumstances, can induce a sense of the sacred. Modern researchers have examined the chemistry of the vapours given off by burning incense and identified the chemical incensole acetate, which is known to induce a feeling of calm. Modern church incense, such as that used on special occasions at Canterbury Cathedral, where Dr Sell now works as a volunteer guide, might also contain rose oil, although the exact recipe of Rosa Mystica, as made by the monks at Alton Abbey, is a secret. Every individual responds to smell in his or her unique way. As Dr Sell points out, when St Paul wrote about the different responses to the gospel as being like different responses to the same odour, “he was touching on a profound truth about human individuality.” To understand smell in modern scientific language — to identify, for instance, that the curious smell encountered on entering an old church is the chemical geosmin — is not to diminish the mystery. “The more deeply I look into the mechanism of odour perception,” Dr Sell writes, “the more I agree with the psalmist who wrote: ‘We are fearfully and wonderfully made.’” -- Ted Harrison * The Church Times *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eForeword by the Dean of Canterbury; Preface; Introduction; How the Sense of Smell Works; Perfume Ingredients in Nature; Sources of Perfume Ingredients; Identifying Perfume Ingredients in the Bible; The Ingredients of Biblical Perfumes; Perfumery; Perfume in the Bible; Perfume at Bethany; Appendix 1 Bible References to Perfume, Odour and the Sense of Smell; Appendix 2 The early medieval windows of Canterbury Cathedral; Bibliography","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741569298775,"sku":"9781788017305","price":18.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781788017305.jpg?v=1720057999"},{"product_id":"the-chemistry-of-plants-perfumes-pigments-and-poisons-9781788019019","title":"The Chemistry of Plants: Perfumes, Pigments and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWhy are some plants so important to humans? The chemistry of the plants has a lot to do with it!      The plant world offers a fascinating way to explore basic chemistry concepts. The spectacular variety of colors, fragrances and other characteristics of plants are driven by the seemingly subtle differences in the structure and properties of organic compounds. Well-known flowers, like daffodils and narcissus, are examples of plants that provide ample perfumes, pigments and poisons as part of their intricate and fascinating chemistry.      This second edition retains it accessibility, expanding on the first edition and combining scientific concepts with colorful pictures and stories in simple, clear language. Readers will find introductory information on some chemistry and plant biology. This prepares them for the more complex chemical structures that compose plant substances, many of them of vital importance to humans. The final chapter has been expanded, in particular the sections on medicinal plants and on genetic modification. The end-of chapter references have been thoroughly updated with articles, books, and relevant websites that illustrate the topics discussed.       Dr Margareta Sequin, an organic chemist and plant enthusiast, has taught popular undergraduate college level courses on plant chemistry to non-chemistry majors and has led numerous field seminars for the general public. The comments and questions from these audiences and the topics that especially captured people's interest have greatly shaped this book.       The Chemistry of Plants addresses an audience with little previous chemistry knowledge, but will appeal to the expert reader looking for an understanding of more complex plant compounds. It can be used both as a text to introduce organic chemistry as it relates to plants and as a text of reference for more advanced readers.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eBasic Plant Chemistry Concepts; The Molecular Building Blocks; Perfumes, Volatile Plant Scents; Colorful Plant Pigments; Poisons and Other Plant Defenses; Plants and People","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741569691991,"sku":"9781788019019","price":28.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781788019019.jpg?v=1720057998"},{"product_id":"nucleic-acids-in-chemistry-and-biology-9781788019041","title":"Nucleic Acids in Chemistry and Biology","description":"\u003cp\u003eThe structure, function and reactions of nucleic acids are central to molecular biology and medicine and are crucial for understanding of the ever-expanding range of complex biological processes involved which are central to life. Revised, extended, updated and lavishly illustrated, this 4th Edition of Nucleic Acids in Chemistry and Biology is a long-awaited standard text for teaching and research in nucleic acids science. It maintains the close integration of chemistry and biology that characterised the earlier editions and contains a major expansion largely focused on the burgeoning growth of RNA science. Written by an international team of leading experts, all with extensive teaching experience, this 4th Edition provides up-to-date and extended coverage of the reactions and interactions of RNA and DNA with proteins and drugs. A brief history of the discovery of nucleic acids is followed by a molecule-based introduction to the structure and biological roles of DNA and RNA and the basics of Genes and Genomes. New key chapters are devoted to non-coding RNA, nucleic acids sequencing, nucleic acid therapeutics, in vitro evolution and aptamers, and protein-RNA interactions. The text is linked to an extensive list of references to make it a definitive reference source. This authoritative volume presents topics in an integrated manner and readable style with full colour illustrations throughout. It is ideal for graduate and undergraduate students of chemistry and biochemistry, biophysics and biotechnology, and molecular biology and medicine. It will be a guidebook for new researchers to the field of nucleic acids science.\u003c\/p\u003e","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741569724759,"sku":"9781788019040","price":61.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781788019040.jpg?v=1720057998"},{"product_id":"natural-product-biosynthesis-chemical-logic-and-enzymatic-machinery-9781839165641","title":"Natural Product Biosynthesis: Chemical Logic and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eAuthored by leading experts in the enzymology of natural product biosynthesis, this completely revised and updated edition provides a description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Although some 500 000 – 600 000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism.    This second edition integrates many new findings into the sets of principles of the first edition that parsed categories of natural product chemistries into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. New chapters include evaluation of a core set of thermodynamically activated but kinetically stable metabolites that power both primary and secondary metabolic pathways. Also, after decades of uncertainty about the existence of various pericyclase classes, a series of genome mining, heterologous expression, and enzymatic activity characterization have validated a plethora of pericyclases over the past decade. The several types of pericyclases are involved in biosynthetic complexity generation of almost every major category of natural products.    This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, pharmacognocists and chemical ecologists, and bioengineers and synthetic biologists.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eMajor Classes of Natural Product Scaffolds and Enzymatic Biosynthetic Machinery; The Chemical Logic for Major Reaction Types; Polyketide Natural Products; Peptide Natural Products I: RiPPs; Peptide Natural Products II: Nonribosomal Peptides; Isoprenoids\/Terpenes; Alkaloids I; Purine- and Pyrimidine-derived Natural Products; Phenylpropanoid Natural Product Biosynthesis; Alkaloids II: Indole Terpenes; Natural Product Oligosaccharides and Glycosides; Oxygenases, Thwarted Oxygenases, and Oxygen-dependent Halogenases; S-Adenosylmethionine; Pericyclases in Natural Product Biosynthesis; Natural Products Isolation and Characterization: Gene-independent Approaches; Natural Products in the Post Genomic Era","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741984698711,"sku":"9781839165641","price":94.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781839165641.jpg?v=1720059562"},{"product_id":"basic-chemistry-for-life-science-students-and-professionals-introduction-to-organic-compounds-and-drug-molecules-9781839167874","title":"Basic Chemistry for Life Science Students and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOrganic chemistry plays a vital role in the pharmaceutical industry. Knowledge of organic compounds is used to inform research and further the discovery and development of new medicines. Likewise, organic chemistry is fundamental to understanding biological reactions, mechanisms and all life sciences in general.    Basic Chemistry for Life Science Students and Professionals is an ideal introduction to organic chemistry in the context of the life sciences and pharmacy related disciplines; utilising drug molecules to illustrate the chemical basis of their efficacy and interaction with biological targets. This book builds upon the basic concepts of organic chemistry to develop the reader’s understanding of the importance of organic chemistry to the life sciences from natural product sources, their synthesis, and approaches to drug discovery.    Ideal for undergraduate students in the natural sciences, this book is also an excellent primer for postgraduates in a variety of disciplines including forensic science and allied-health programmes as well as professionals working in related fields seeking a comprehensive introduction to organic chemistry in the context of pharmaceuticals.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction to Organic Compounds and Covalent Bonding; Polarity of Bonds, Electronegativity, and Intermolecular Forces; Types of Organic Compounds, Nomenclature, and Basic Reactions: Alkanes and Cycloalkanes; Types of Organic Compounds, Nomenclature, and Basic Reactions: Alkenes, Cycloalkenes and Other Unsaturated Hydrocarbons; 5 Types of Organic Compounds, Nomenclature, and Basic Reactions: Functional Groups; Isomerism in Organic Compounds and Drug Molecules: Chemistry and Significance in Biology; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Amino Acids to  Proteins; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Monosaccharides to Complex Carbohydrates; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Fatty Acids to Complex Lipids and Fat; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Nucleotides to Nucleic Acids; Physicochemical Properties of Organic Compounds and Drug Molecules; Drug-Target Interactions; Structural Diversity and Sources of Drugs: From Nature to Synthetic and Recombinant DNA Technology","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741985091927,"sku":"9781839167874","price":42.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781839167874.jpg?v=1720059564"},{"product_id":"garlic-and-other-alliums-the-lore-and-the-science-9781849731805","title":"Garlic and Other Alliums: The Lore and The","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe name \"Allium\" is said to come from the Greek word to avoid because of its offensive smell. The genus Allium includes more than 800 species of which only a few have been cultivated as foods. Many of the other members of this genus are popular with gardeners as easy to maintain perennials, although the smell of some members of the genus can be off-putting. The smell is a consequence of breakdown of sulfur-containing compounds which is a characteristic of this family of plants. Garlic, onions, leeks, chives and other members of the genus Allium occupy a unique position both as edible plants and herbal medicines, appreciated since the dawn of civilization. Alliums have been featured through the ages in literature, where they are both praised and reviled, as well as in architecture and the decorative arts. Garlic pills are top-selling herbal supplements while garlic-based products show considerable promise as environmentally friendly pesticides. The remarkable properties of the alliums can be understood based on the occurrence of a number of relatively simple sulfur-containing chemical compounds ingeniously packaged by nature in these plants. This unique book, with a foreword by 1990 Nobel Laureate E.J. Corey, outlines the extensive history and the fascinating past and present uses of these plants, sorting out fact from fiction based upon detailed scrutiny of historic documents as well as numerous laboratories studies. Readers will be entertained and educated as they learn about early cultivation of garlic and other alliums while being introduced to the chemistry and biochemistry. They will learn how alliums have been portrayed and used in literature, poetry, the arts and how alliums are featured in the world's oldest cookbook. Technical material is presented in a manner understandable to a general audience, particularly through the use of illustrations to simplify more difficult concepts and explain how experimental work is conducted. The book is heavily illustrated with examples of alliums in art, literature, agriculture, medicine and other areas and includes rare botanical drawings of many members of the genus Allium. Essential reading for anyone with a general interest in science, the book is written at a level accessible to experts and non-experts alike. It has sufficient additional detail and references to satisfy both those wanting to know more, as well as researchers in disciplines as diverse as archaeology, medicine, ecology, pharmacology, food and plant sciences, agriculture, and organic chemistry.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eThis book brings to mind the poet Horace's formula for successful writing: He wins every hand who mingles profit with pleasure, by delighting and instructing the reader at the same time. Eric Block has certainly mixed the useful and the sweet in his book.I started BlockÆs book as a reviewer and became an admirer. A book that contributes so richly to my teaching and understanding of chemistry is a rare pleasure. -- Stephen R Pruett * ASAPDOI: 10.1021\/ed2001889Publication Date (Web): April 18, 2011 *\u003cbr\u003eBlock writes well and passionately...gives a very balanced assessment of the claims and evidence for the health benefits of eating or taking allium supplements, primarily garlic.The book is well written and illustrated: a particular bonus is the inclusion of 27 coloured botanical prints from a volume of Flora Germanica. It will probably be of most interest to students and researchers familiar with plant biochemistry, but there is also something for those curious about this group of plants that play a prominent role in cooking, culture and chemistry. -- Ian J McEwan * Biochemist e-volution *\u003cbr\u003e'Both entertaining, and at the same time a challenging read, there is a lot of valuable information in this book.My hat is off to Eric for the amazing contribution to the world's collection of allium science.' -- Bob Dunkel * The Garlic Press *\u003cbr\u003e'Block presents an entertaining and informative account of the history of garlic, onions, and other alliums. This ethnobotanic work is truly interdisciplinary, intended for a wide audience of historians, sociologists, chemists, cooks, botanists, and naturalists.Summing Up: Highly recommended. Academic, professional, and general libraries, all levels.' -- L Swatzell, Southeast Missouri State University * Choice, v 47, No 10 *\u003cbr\u003e'...well organized, and presents something for everyone. It should be said right away that this is far from a typical ôchemistryö book due to both the varied content and the style of presentation....it all works rather well together; it is a fine example of how complex chemistry can be contextualized in a fascinating and often entertaining way.' -- Derek A Pratt * Angew. Chem. Int. Ed., 2010, 49, 2 *\u003cbr\u003e'There is some fascinating chemistry told here. Both the chemistry itself and the story of its revelation are given in detail.Within the book there are some fascinating anecdotes - a town in America where it is illegal to attend a theatre after eating raw onions, the resigned reflection that despite its benefits 'garlic mouthwash is unlikely to be a winning consumer product' and the warning that garlic in your socks will come out on your breath. Now there's an experiment any of us can try.' -- David Quick * Education in Chemistry *\u003cbr\u003e'...enjoyment of this book should not be limited to scientists. The book is a virtual encyclopedia of garlic and onion facts, and while it may make a necessary addition to the food chemistÆs library, it is something that any foodie, especially a garlic lover, can enjoy.' -- Thomas J Mansell * Food and Foodways, 18: 3, 170-172 *\u003cbr\u003eThis is a fascinating book written by an authority on the chemistry of the edible alliums, which include garlic, onions, leeks and chives. The book is well written and up-to-date. I can thoroughly recommend this book not just to natural product chemists but also to all those who have grown these plants in the garden or enjoyed eating them. It contains many anecdotes and quotations to enliven a chemist's dinner party. -- Jim Hanson * Chemistry World *\u003cbr\u003eWhat do garlic and onions have in common with gunpowder? A lot. TheyÆre incendiary. They can do harm and they delight. Sulfur is central to their powers. And they helped inspire the work of a chemist who has just published a welcome treatise on the smelly yet indispensable allium family. Dr. BlockÆs book may be the definitive word on the alliums for the moment, but as it and he make clear, there are new flavors to look forward t. -- Harold McGee * The New York Times *\u003cbr\u003eThis book by Eric Block is a synthesis of his four decades of distinguished work with alliums.His account of this ever-increasing knowledge is accessible and will even entertain readers without a deep knowledge of chemistry.Block may look at the world through garlic-tinged lenses, but in this book he is very good at getting readers to see it his way -- Meriel Jones * Chemistry and Industry *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Allium Botany and Cultivation, Ancient and Modern; 2. All Things Allium: Alliums in Literature, the Arts and Culture; 3. Allium Chemistry 101: Historical Highlights, Fascinating Facts and Unusual Uses for Alliums; 4. Chemistry in a Salad Bowl: Allium Chemistry and Biochemistry; 5. Alliums in Folk and Complementary Medicine; 6. Alliums in the Environment: Allelopathy and Allium-Derived Attractants, Antibiotics, Herbicides, Pesticides and Repellents","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48742296355159,"sku":"9781849731805","price":23.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781849731805.jpg?v=1720060817"},{"product_id":"fruit-oils-chemistry-and-functionality-9783030124755","title":"Fruit Oils: Chemistry and Functionality","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eFruit Oils: Chemistry and Functionality\u003c\/i\u003e presents a comprehensive overview of recent advances in the chemistry and functionality of lipid bioactive phytochemicals found in fruit oils. The chapters in this text examine the composition, physicochemical characteristics and organoleptic attributes of each of the major fruit oils. The nutritional quality, oxidative stability, and potential food and non-foodapplications of these oils are also extensively covered. The potential health benefits of the bioactive lipids found in these fruit oils are also a focus of this text. For each oil presented, the levels of \u003ci\u003eomega\u003c\/i\u003e-9, \u003ci\u003eomega\u003c\/i\u003e-6 and \u003ci\u003eomega\u003c\/i\u003e-3 fatty acids are specified, indicating the level of health-promoting traits exhibited in each. \u003c\/p\u003e\u003cp\u003eThe oils and fats extracted from fruits generally differ from one another both in terms of their major and minor bioactive constituents. The methods used to extract oils and fats as well as the processing techniques such as refining, bleaching and deodorization affect their major and minor constituents. In addition, different post-processing treatments of fruit oils and fats may alert or degrade important bioactive constituents. Treatments such as heating, frying, cooking and storage and major constituents such as sterols and tocols are extensively covered in this text. \u003c\/p\u003e\u003cp\u003eAlthough there have been reference works published on the composition and biological properties of lipids from oilseeds, there is currently no book focused on the composition and functionality of fruit oils. \u003ci\u003eFruit Oils: Chemistry and Functionality\u003c\/i\u003e aims to fill this gap for researchers, presenting a detailed overview of the chemical makeup and functionality of all the important fruit oils.         \u003cbr\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e            \u003c\/p\u003e  \u003cp\u003e            \u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eIntroduction to fruit oils: chemistry and functionality\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eOlive (\u003cem\u003eOlea europaea\u003c\/em\u003e) Oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e \u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePalm (\u003ci\u003eElaeis guineensis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCranberry (\u003ci\u003eVaccinium macrocarpon\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eArgan (\u003ci\u003eArgania spinosa\u003c\/i\u003e L.) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eSea Buckthorn (\u003cem\u003eHippophaë rhamnoides\u003c\/em\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eAvocado (\u003ci\u003ePersea americana\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGoldenberry (\u003ci\u003ePhysalis peruviana\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCactus (\u003ci\u003eO. ficus-indica\u003c\/i\u003e) pear oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePumpkin (\u003ci\u003eCucurbita pepo\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCoriander (\u003ci\u003eCoriandrum sativum\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eHazelnut (\u003ci\u003eCorylus avellana\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eAlmond (\u003ci\u003ePrunus dulcis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePistachio (\u003ci\u003ePistacia vera\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eWalnut (\u003ci\u003eJuglans regia\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eChestnut (\u003ci\u003eCastanea sativa)\u003c\/i\u003e oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePassion (\u003ci\u003ePassiflora edulis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGac (\u003ci\u003eMomordica cochinchinensis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePomegranate (\u003ci\u003ePunica granatum\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGrape (\u003cem\u003eVitis vinifera\u003c\/em\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eApple (\u003ci\u003eMalus pumila\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eWatermelon (\u003ci\u003eCitrullus lanatus\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eAmla (\u003ci\u003ePhyllanthus emblica\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eBuriti (\u003ci\u003eMauritia flexuosa\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eBael (\u003ci\u003eAegle marmelos\u003c\/i\u003e )oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eSandalwood (\u003ci\u003eSantalum album\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCoconut (\u003ci\u003eCocos nucifera\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCitrus oils\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eKiwifruit (\u003ci\u003eActinidia deliciosa\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGuava (\u003ci\u003ePsidium guajava\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eDate palm (\u003ci\u003ePhoenix dactylifera\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eApricot (\u003ci\u003ePrunus armeniac\u003c\/i\u003ea) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eMangongo\/manketti  (\u003ci\u003eSchinziophyton rautanenii\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePapaya (\u003ci\u003eCarica papaya\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003ci\u003eCelastrus paniculatus\u003c\/i\u003e\u003c\/b\u003e\u003ci\u003e \u003c\/i\u003e\u003cb\u003eoil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003ci\u003eSemecarpus anacardium\u003c\/i\u003e oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ekachnar (\u003ci\u003eBauhinia purpurea\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cp\u003e\u003cb\u003eButtercup tree [\u003ci\u003eMadhuca\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e  \u003cb\u003e\u003ci\u003elongifolia\u003c\/i\u003e (Koenig)] oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743024099671,"sku":"9783030124755","price":75.99,"currency_code":"GBP","in_stock":true}]},{"product_id":"spectroscopic-methods-in-organic-chemistry-9783030182519","title":"Spectroscopic Methods in Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eThis book is a well-established guide to the interpretation of the mass, ultraviolet, infrared and nuclear magnetic resonance spectra of organic compounds. It is designed for students of organic chemistry taking a course in the application of these techniques to structure determination. The text also remains useful as a source of data for organic chemists to keep on their desks throughout their career.\u003c\/p\u003e  \u003cp\u003e\u003c\/p\u003e\u003cp\u003eIn the seventh edition, substantial portions of the text have been revised reflecting knowledge gained during the author's teaching experience over the last seven years. The chapter on NMR has been divided into two separate chapters covering the 1D and 2D experiments. The discussion is also expanded to include accounts of the physics at a relatively simple level, following the development of the magnetization vectors as each pulse sequence is introduced. The emphasis on the uses of NMR spectroscopy in structure determination is retained. Worked examples and problem sets are included on a chapter level to allow students to practise their skills by determining the chemical structures of unknown compounds.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eChapter 1: Mass spectra \u003cp\u003e1.1       Introduction                                                                                               \u003c\/p\u003e  1.2       Ion production                                                                                           \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.2.1  Electron impact (EI)                                                                         \u003c\/p\u003e              1.2.2  Chemical Ionisation (CI)                                                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.2.3  Electrospray ionisation (ESI)                                                            \u003c\/p\u003e              1.2.4  Fast ion bombardment (FIB or LSIMS)                                            \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.2.5  Laser desorption (LD) and matrix-assisted laser\u003c\/p\u003e                       desorption (MALDI)                                                                        \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e1.3       Ion analysis                                                                                               \u003c\/p\u003e              1.3.1  Magnetic analysers                                                                          \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e          1.3.2  Time-of–flight (TOF) analysers                                                       \u003c\/p\u003e              1.3.3  Quadrupole analysers                                                                      \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.3.4  Ion cyclotron resonance (ICR) analysers                                         \u003c\/p\u003e              1.3.5  Ion-trap analysers                                                                            \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e1.4       Structural information from EI mass spectra                                             \u003c\/p\u003e              1.4.1  The features of an EI spectrum                                                       \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.4.2  The molecular ion                                                                            \u003c\/p\u003e              1.4.3  Isotopic abundances                                                                        \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.4.4  Identifying the molecular ion                                                           \u003c\/p\u003e              1.4.5  Fragmentation in EI spectra                                                            \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e1.5       Fragmentation in CI and FIB spectra                                                       \u003c\/p\u003e              1.5.1  Fragmentation in CI spectra                                                           \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.5.2  Fragmentation in FIB (LSMIS) spectra                                           \u003c\/p\u003e  1.6       Some examples of mass spectrometry in action                                      \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.6.1 San Joaquin oil                                                                               \u003c\/p\u003e              1.6.2 Oleic acid                                                                                       \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.6.3 The oviposition pheromone                                                            \u003c\/p\u003e              1.6.4 Identifying antibodies                                                                     \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            1.6.5 The ESI spectra of melittin and the human parathyroid hormone   \u003c\/p\u003e              1.6.6 ESI-FT-ICR and ESI-FT-Orbitrap spectra                                       \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e1.7       Separation coupled to mass spectrometry                                                \u003c\/p\u003e  \u003cp\u003e            1.7.1  GC\/MS and LC\/MS                                                                        \u003c\/p\u003e  \u003cp\u003e            1.7.2  MS\/MS                                                                                           \u003c\/p\u003e  1.8       Interpreting the spectrum of an unknown                                                \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e1.9       Internet                                                                                                    \u003c\/p\u003e  1.10     Bibliography                                                                                            \u003cp\u003e\u003c\/p\u003e  1.11     Problems                                                                                                 \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e1.12     Tables of data                                                                                          \u003c\/p\u003e  Chapter 2: Ultraviolet and visible spectra 2.1       Introduction                                                                                             \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.2       Chromophores                                                                                         \u003c\/p\u003e  \u003cp\u003e2.3       The absorption laws                                                                                \u003c\/p\u003e  2.4       Measurement of the spectrum                                                                 \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.5       Vibrational fine structure                                                                         \u003c\/p\u003e  2.6       Selection rules and intensity                                                                    \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.7       Solvent effects                                                                                        \u003c\/p\u003e  2.8       Searching for a chromophore                                                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.9       Definitions                                                                                              \u003c\/p\u003e  2.10     Conjugated dienes                                                                                   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.11     Polyenes and poly-ynes                                                                           \u003c\/p\u003e  \u003cp\u003e2.12     Ketones and aldehydes; p®p* transitions                                               \u003c\/p\u003e  \u003cp\u003e2.13     Ketones and aldehydes; n®p* transitions                                               \u003c\/p\u003e  \u003cp\u003e2.14     a,b-Unsaturated acids, esters, nitriles and amides                                   \u003c\/p\u003e  \u003cp\u003e2.15     Aromatic compounds                                                                              \u003c\/p\u003e  2.16     Quinones                                                                                                 \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.17     Corroles, chlorins and porphyrins                                                           \u003c\/p\u003e  2.18     Non-conjugated interacting chromophores                                              \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.19     The effect of steric hindrance to coplanarity                                           \u003c\/p\u003e  2.20     Internet                                                                                                    \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e2.21     Bibliography                                                                                            \u003c\/p\u003e  2.22     Problems                                                                                                 \u003cp\u003e\u003c\/p\u003e  Chapter 3: Infrared spectra 3.1       Introduction                                                                                             \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3.2       Preparation of samples and examination in an infrared spectrometer      \u003c\/p\u003e  3.3       Selection rules                                                                                         \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3.4       The infrared spectrum                                                                             \u003c\/p\u003e  \u003cp\u003e3.5       The use of the tables of characteristic group frequencies                        \u003c\/p\u003e  3.6       Stretching frequencies of single bonds to hydrogen                                \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3.7     Stretching frequencies of triple and cumulated double bonds                 \u003c\/p\u003e  \u003cp\u003e3.8       Stretching frequencies in the double-bond region                                    \u003c\/p\u003e  3.9       Characteristic vibrations of aromatic rings                                               \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3.10     Groups absorbing in the fingerprint region                                              \u003c\/p\u003e  3.11     Raman spectra                                                                                         \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3.12     Internet                                                                                                    \u003c\/p\u003e  3.13     Bibliography                                                                                            \u003cp\u003e\u003c\/p\u003e  3.14     Problems                                                                                                 \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3.15     Correlation charts                                                                                    \u003c\/p\u003e  3.16     Tables of data                                                                                          \u003cp\u003e\u003c\/p\u003e  Chapter 4: 1D-NMR spectra 4.1       Nuclear spin and resonance                                                                     \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.2       Taking a spectrum                                                                                   \u003c\/p\u003e  4.3       The chemical shift                                                                                   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.4       Factors affecting the chemical shift                                                       \u003c\/p\u003e              4.4.1    The inductive effect                                                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.4.2    Anisotropy of chemical bonds                                                  \u003c\/p\u003e              4.4.3    Polar effects of conjugation                                                      \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.4.4    Van der Waals forces                                                                \u003c\/p\u003e              4.4.5    Isotope effects                                                                           \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.4.6    Estimating a chemical shift                                                        \u003c\/p\u003e              4.4.7    Hydrogen bonds                                                                        \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.4.8    Solvent effects and temperature                                                \u003c\/p\u003e  \u003cp\u003e4.5       Spin-spin coupling to \u003csup\u003e13\u003c\/sup\u003eC                                                                       \u003c\/p\u003e  \u003cp\u003e            4.5.1    \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e2\u003c\/sup\u003eH Coupling                                                                        \u003c\/p\u003e  \u003cp\u003e            4.5.2    \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e1\u003c\/sup\u003eH Coupling                                                                        \u003c\/p\u003e  \u003cp\u003e            4.5.3    \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e13\u003c\/sup\u003eC Coupling                                                                       \u003c\/p\u003e  \u003cp\u003e4.6       \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH Coupling—multiplicity and coupling patterns                             \u003c\/p\u003e  \u003cp\u003e            4.6.1    \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH Vicinal coupling (\u003csup\u003e3\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e)                                                    \u003c\/p\u003e              4.6.2    AB systems                                                                               \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.6.3    \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH Geminal coupling (\u003csup\u003e2\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e)                                                  \u003c\/p\u003e  \u003cp\u003e            4.6.4    \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH Long-range coupling (\u003csup\u003e4\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e and \u003csup\u003e5\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e)                               \u003c\/p\u003e              4.6.5    Deviations from first-order coupling                                         \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.7       \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH Coupling—the magnitude of coupling constants                         \u003c\/p\u003e              4.7.1    The sign of coupling constants                                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.7.2    Vicinal coupling (\u003csup\u003e3\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e)                                                              \u003c\/p\u003e  \u003cp\u003e            4.7.3    Geminal coupling (\u003csup\u003e2\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e)                                                            \u003c\/p\u003e  \u003cp\u003e            4.7.4    Long-range coupling (\u003csup\u003e4\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e and \u003csup\u003e5\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eHH\u003c\/sub\u003e)                                         \u003c\/p\u003e  \u003cp\u003e            4.7.5    C–H coupling (\u003csup\u003e1\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eCH\u003c\/sub\u003e,\u003csup\u003e 2\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eCH\u003c\/sub\u003e and \u003csup\u003e3\u003c\/sup\u003e\u003ci\u003eJ\u003c\/i\u003e\u003csub\u003eCH\u003c\/sub\u003e)                                            \u003c\/p\u003e  \u003cp\u003e4.8       Coupling from \u003csup\u003e1\u003c\/sup\u003eH and \u003csup\u003e13\u003c\/sup\u003eC to \u003csup\u003e19\u003c\/sup\u003eF and \u003csup\u003e31\u003c\/sup\u003eP                                               \u003c\/p\u003e  \u003cp\u003e            4.8.1    \u003csup\u003e13\u003c\/sup\u003eC NMR spectra of compounds containing \u003csup\u003e19\u003c\/sup\u003eF and \u003csup\u003e31\u003c\/sup\u003eP             \u003c\/p\u003e  \u003cp\u003e            4.8.2    \u003csup\u003e1\u003c\/sup\u003eH NMR spectra of compounds containing \u003csup\u003e19\u003c\/sup\u003eF and \u003csup\u003e31\u003c\/sup\u003eP              \u003c\/p\u003e  4.9       Relaxation and its consequences                                                           \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.9.1    Longitudinal relaxation                                                              \u003c\/p\u003e              4.9.2    Transverse relaxation and exchange                                          \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.10     Improving the NMR spectrum                                                               \u003c\/p\u003e              4.10.1  The effect of changing the magnetic field                                 \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.10.2  Solvent effects                                                                          \u003c\/p\u003e              4.10.3  Shift reagents                                                                             \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.11     Spin decoupling                                                                                     \u003c\/p\u003e              4.11.1  Simple spin decoupling                                                             \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.11.2  Difference decoupling                                                               \u003c\/p\u003e  4.12     Identifying spin systems—1D-TOCSY                                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.13     The nuclear Overhauser effect                                                              \u003c\/p\u003e              4.13.1  Origins                                                                                       \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.13.2  NOE-Difference spectra                                                            \u003c\/p\u003e  4.14     The rotating frame of reference                                                             \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.15     Assignment of CH\u003csub\u003e3\u003c\/sub\u003e, CH\u003csub\u003e2\u003c\/sub\u003e, CH and fully substituted carbons in \u003csup\u003e13\u003c\/sup\u003eC NMR \u003c\/p\u003e  \u003cp\u003e            4.15.1  The Attached Proton Test (APT)                                                \u003c\/p\u003e              4.15.2  DEPT                                                                                         \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.16     Hints for structure determination using 1D-NMR                                  \u003c\/p\u003e              4.16.1  Carbon spectra                                                                          \u003cp\u003e\u003c\/p\u003e              4.16.2  Proton spectra                                                                            \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e4.17     Further information                                                                               \u003c\/p\u003e              4.17.1  The internet                                                                               \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            4.17.2  Bibliography                                                                              \u003c\/p\u003e  4.18     Tables of data                                                                                        \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  Chapter 5: 2D-NMR spectra \u003cp\u003e5.1       The basic pulse sequence                                                                      \u003c\/p\u003e5.2       COSY                                                                                                    \u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.2.1    Cross peaks from scalar coupling                                              \u003c\/p\u003e              5.2.2    Polarisation transfer                                                                   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.2.3    The origin of cross peaks                                                          \u003c\/p\u003e              5.2.4    Displaying COSY spectra                                                          \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.2.5    Interpreting COSY spectra                                                         \u003c\/p\u003e              5.2.6    Axial peaks                                                                               \u003cp\u003e\u003c\/p\u003e              5.2.7    Gradient pulses                                                                          \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.2.8    DQF-COSY                                                                               \u003c\/p\u003e              5.2.9    Phase structure in COSY spectra                                               \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e5.3       2D-TOCSY                                                                                            \u003c\/p\u003e  5.4       NOESY                                                                                                 \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e5.5       Cross-correlated 2D spectra identifying 1-bond connections                 \u003c\/p\u003e  \u003cp\u003e            5.5.1    Heteronuclear Multiple Quantum Coherence (HMQC) spectra  \u003c\/p\u003e              5.5.2    Heteronuclear Single Quantum Coherence (HSQC) spectra       \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.5.3    Examples of HSQC spectra                                                       \u003c\/p\u003e  \u003cp\u003e            5.5.4    Non-uniform sampling (NUS)                                                   \u003c\/p\u003e              5.5.5    Cross-peak detail—determining the sign of coupling constants \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.5.6    CLIP-HSQC                                                                               \u003c\/p\u003e  \u003cp\u003e            5.5.7    Deconvoluting a \u003csup\u003e1\u003c\/sup\u003eH spectrum using the HSQC spectrum           \u003c\/p\u003e  \u003cp\u003e            5.5.8    HSQC-TOCSY                                                                          \u003c\/p\u003e              5.5.9    HETCOR                                                                                   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e5.6       Cross-correlated 2D spectra identifying 2- and 3-bond connections      \u003c\/p\u003e  \u003cp\u003e            5.6.1    The HMBC pulse sequence                                                       \u003c\/p\u003e              5.6.2    HMBC spectra                                                                           \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e5.7       Some specialised NMR techniques                                                        \u003c\/p\u003e              5.7.1    ADEQUATE—identifying \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e13\u003c\/sup\u003eC connections                         \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e            5.7.2    INADEQUATE—identifying \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e13\u003c\/sup\u003eC connections                     \u003c\/p\u003e  \u003cp\u003e            5.7.3    HSQC-HECADE—measuring the sign and magnitude of \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e1\u003c\/sup\u003eH \u003c\/p\u003e                          coupling constants                                                                     \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e5.8       Three- and four-dimensional NMR                                                       \u003c\/p\u003e  5.9       Hints for structure determination using 2D-NMR                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e5.10     Bibliography                                                                                          \u003c\/p\u003e  5.11     Table of information                                                                             \u003cp\u003e\u003c\/p\u003e  Chapter 6: Worked examples in structure determination 6.1       General approach                                                                                  \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e6.2       Simple worked examples using \u003csup\u003e13\u003c\/sup\u003eC NMR alone                                    \u003c\/p\u003e  \u003cp\u003e6.3       Simple worked examples using \u003csup\u003e1\u003c\/sup\u003eH NMR alone                                     \u003c\/p\u003e  \u003cp\u003e6.4     Simple worked examples using the combined application of MS, UV, IR and 1D-NMR spectroscopic methods          \u003c\/p\u003e  6.5     Simple worked examples using the combined application of MS, UV, IR and 1D-NMR and 2D-NMR spectroscopic methods                                                                          \u003cp\u003e\u003c\/p\u003e  Chapter 7: Problem sets \u003cp\u003e7.1       Chemical shift problems                                                              \u003c\/p\u003e  \u003cp\u003e7.2       1D-NMR chemical shift and coupling problems                                 \u003c\/p\u003e  \u003cp\u003e7.3       Problems using all the spectroscopic methods                                  \u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  Answers to problems 1-34                                                                            \u003cp\u003e\u003c\/p\u003e  Index                                                                                                                                                  ","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743026098519,"sku":"9783030182519","price":52.24,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783030182519.jpg?v=1720063798"},{"product_id":"modern-ylide-chemistry-applications-in-ligand-design-organic-and-catalytic-transformations-9783319895444","title":"Modern Ylide Chemistry: Applications in Ligand","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis volume covers recent advances in the chemistry of ylidic compounds with focus on their application in the design of ligands with unique donor properties, the development of novel organic transformations as well as the use of ylides in homogenous catalysis. Thereby, this volume particularly aims at the community of organic and organometallic chemists engaged in synthetic chemistry and catalysis as well as in the use of special ligands for the stabilization of unusual main group element species and the “transition-metal free” activation of element-element\/hydrogen bonds. These fields of research are highly active and vivid research areas to which ylide chemistry has only recently started to contribute, but has already led to fascinating developments in most different directions. This volume highlights these recent developments, thus giving not only an overview over the past achievements, but also possibilities for future applications. To this end, the chapters selected in this volume combine different aspects of ylide chemistry, starting with theoretical aspects in ligand design followed by synthetic organic methods, catalytic transformations and complex chemistry. \u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eStructure and Reactivity of Carbones and Ylide Stabilized Carbenes: Contributions from Theory.- Synthesis, Structure, and Reactivity of Carbodiphosphoranes,Carbodicarbenes,and Related Species.- Synthesis and Structure of Carbodicarbenes and Their Application in Catalysis.- Sulfur Ylides in Organic Synthesis and Transition Metal Catalysis.- Reactivity and Applications of α-Metalated Ylides.\u003c\/p\u003e","brand":"Springer International Publishing AG","offers":[{"title":"Default Title","offer_id":48743108411735,"sku":"9783319895444","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"handbook-of-synthetic-photochemistry-9783527323913","title":"Handbook of Synthetic Photochemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eUnique in its focus on preparative impact rather than mechanistic details, this handbook provides an overview of photochemical reactions classed according to the structural feature that is built in the photochemical step, so as to facilitate use by synthetic chemists unfamiliar with this topic.  An introductory section covers practical questions on how to run a photochemical reaction, while all classes of the most important photocatalytic reactions are also included.\u003cbr\u003e Perfect for organic synthetic chemists in academia and industry.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"Given its organization and practical emphasis, I believe that this book would make an outstanding addition to the library of any synthetic organic chemist. It should certainly be on the acquisition lists of all institutional libraries.\" (Journal of the American Chemical Society, November 2010)  \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePHOTOCHEMICAL METHODS\u003cbr\u003e Photochemistry and Organic Synthesis\u003cbr\u003e Irradiation Apparatus\u003cbr\u003e Further Experimental Parameters\u003cbr\u003e Photochemical Steps in Synthesis\u003cbr\u003e CARBON-CARBON BOND FORMATION BY PHOTOELIMINATION OF SMALL MOLECULES IN SOLUTION AND IN CRYSTALS\u003cbr\u003e Introduction\u003cbr\u003e Photochemical  C-C Bond Formation in Solution\u003cbr\u003e Reactions in the Solid State\u003cbr\u003e Conclusions\u003cbr\u003e INTERMOLECULAR ADDITION REACTIONS ONTO C-C MULTIPLE BONDS\u003cbr\u003e Introduction\u003cbr\u003e Addition to C-C Double Bonds\u003cbr\u003e Addition to C-C Triple Bonds\u003cbr\u003e Conclusions\u003cbr\u003e FORMATION OF A 3-MEMBERED RING\u003cbr\u003e Introduction\u003cbr\u003e Di-Pi-Methane Rearrangement\u003cbr\u003e Oxa-Di-Pi-Methane Rearrangement and Related Rearrangements\u003cbr\u003e [2+1] Cycloaddition of Alkenes with Carbenes\u003cbr\u003e Formation of a Cyclopropane Via Intramolecular Hydrogen Abstraction\u003cbr\u003e [3+2] Cycloaddition of Arenes with Alkenes\u003cbr\u003e Photochemical Synthesis of Three-Membered Heterocycles\u003cbr\u003e FORMATION OF A 4-MEMBERED RING I\u003cbr\u003e Introduction\u003cbr\u003e [2+2]-Photocycloaddition of Non Conjugated Alkenes\u003cbr\u003e [2+2]-Photocycloaddition of Aromatic Compounds\u003cbr\u003e Photochemical Electrocyclic Reactions\u003cbr\u003e Intramolecular Gamma-Hydrogen Abstraction (Yang Reaction)\u003cbr\u003e Metal Catalyzed Reactions\u003cbr\u003e Various Methods\u003cbr\u003e Conclusions\u003cbr\u003e FORMATION OF A 4-MEMBERED RING II\u003cbr\u003e Introduction\u003cbr\u003e [2+2]-Photocycloaddition of Enones (Substrate Type A1)\u003cbr\u003e [2+2]-Photocycloaddition of Vinylogous Amides and Esters (Substrate Clases A2 and A3)\u003cbr\u003e [2+2]-Photocycloaddition of Alpha, Beta-Unsaturated Carboxylic Acid Derivatives (Substrate Classes A4, A5 and A6)\u003cbr\u003e Conclusions and Perspectives\u003cbr\u003e FORMATION OF A 4-MEMBERED RING III (OXETANES)\u003cbr\u003e Introduction\u003cbr\u003e Generally Accepted Mechanisms of the Paterno-Buchi Reaction\u003cbr\u003e Regio- and Siteselective Synthesis of Oxetanes\u003cbr\u003e Stereoselective Syntheses of Oxetanes\u003cbr\u003e Conclusive Remarks\u003cbr\u003e FORMATION OF A 5-MEMBERED RING\u003cbr\u003e Formation of Five-Membered Ring: Intramolecular Delta-H Abstraction\u003cbr\u003e Formation of Five-Membered Rings Via [3+2]-Cycloadditions\u003cbr\u003e Photochemical Electrocyclization Reactions: Synthesis of Fused Five-Membered Ring Compounds\u003cbr\u003e Photoinduced Electron Transfer Radical Cation Mediated Cyclizations: Synthesis of Five-Membered Carbocyclic as well as Heterocyclic Ring Systems\u003cbr\u003e FORMATION OF 6-MEMBERED RING (AND LARGER RINGS)\u003cbr\u003e Introduction\u003cbr\u003e Photoelectron Transfer Initiated Cyclizations\u003cbr\u003e Photoinduced 6Pi-Electrocyclization\u003cbr\u003e Photocycloaddition Reactions\u003cbr\u003e Remote Intramolecular Hydrogen Abstraction\u003cbr\u003e Ring Contraction and Ring Enlargement\u003cbr\u003e Other Reactions\u003cbr\u003e Summary\u003cbr\u003e AROMATIC AND HETEROAROMATIC SUBSTITUTION BY SRN1 AND SN1 REACTIONS\u003cbr\u003e Introduction\u003cbr\u003e General Mechanistic Features\u003cbr\u003e Carbon-Carbon Bond Formation\u003cbr\u003e Carbon-Heteroatom Bond Formation\u003cbr\u003e Synthesis of Bi, Tri, and Poliaryls\u003cbr\u003e Synthesis of Carbocycles and Heterocycles\u003cbr\u003e SINGLET OXYGEN AS A REAGENT IN ORGANIC SYNTHESIS\u003cbr\u003e Introduction\u003cbr\u003e Dioxetanes\u003cbr\u003e Endoperoxides\u003cbr\u003e Allylic Hydroperoxides\u003cbr\u003e Tandem Singlet Oxygen Reactions\u003cbr\u003e Conclusion\u003cbr\u003e SYNTHESIS OF HETEROAROMATICS VIA REARRANGEMENT REACTIONS\u003cbr\u003e Introduction\u003cbr\u003e Synthesis of Five-Membered Rings with One Heteroatom\u003cbr\u003e Synthesis of Five-Membered Rings with Two Heteroatoms\u003cbr\u003e Synthesis of Five-Membered Rings with Three Heteroatoms\u003cbr\u003e Synthesis of Six-Membered Rings\u003cbr\u003e Synthesis of Seven-Membered Rings\u003cbr\u003e Concluding Remarks\u003cbr\u003e PHOTOLABILE PROTECTING GROUPS IN ORGANIC SYNTHESIS\u003cbr\u003e Introduction\u003cbr\u003e Photolabile Protecting Groups\u003cbr\u003e Chromatic Orthogonality\u003cbr\u003e Two-Photons Absorption\u003cbr\u003e Perspectives and Conclusion\u003cbr\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":48743115915607,"sku":"9783527323913","price":128.66,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783527323913.jpg?v=1720064180"},{"product_id":"click-reactions-in-organic-synthesis-9783527339167","title":"Click Reactions in Organic Synthesis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures. \u003cbr\u003e By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of Contributors XI\u003c\/p\u003e \u003cp\u003ePreface XV\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Click Chemistry:Mechanistic and Synthetic Perspectives 1\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eRamesh Ramapanicker and Poonam Chauhan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Cycloaddition Click Reactions 2\u003c\/p\u003e \u003cp\u003e1.1.1 Azide–Alkyne Huisgen 1,3-Dipolar Cycloaddition 2\u003c\/p\u003e \u003cp\u003e1.1.2 Copper-Catalyzed Azide–Alkyne Cycloaddition (CuAAC) Click Reaction 2\u003c\/p\u003e \u003cp\u003e1.1.2.1 Mechanism of CuAAC Click Reactions 5\u003c\/p\u003e \u003cp\u003e1.1.2.2 Catalysts used for CuAAC Click Reactions 6\u003c\/p\u003e \u003cp\u003e1.1.2.3 Ligands used for CuAAC Click Reactions 7\u003c\/p\u003e \u003cp\u003e1.1.3 Ruthenium-Catalyzed Azide–Alkyne Cycloaddition (RuAAC) Click Reactions 7\u003c\/p\u003e \u003cp\u003e1.1.3.1 Mechanism of RuAAC Click Reactions 8\u003c\/p\u003e \u003cp\u003e1.1.4 Strain-Promoted Azide–Alkyne Cycloaddition (SPAAC) Reactions 8\u003c\/p\u003e \u003cp\u003e1.1.5 Organocatalytic Triazole Formation 10\u003c\/p\u003e \u003cp\u003e1.2 Thiol-Based Click Reactions 12\u003c\/p\u003e \u003cp\u003e1.2.1 Radical Click Reactions of Thiols 12\u003c\/p\u003e \u003cp\u003e1.2.1.1 Thiol–Ene Radical Click Reaction 12\u003c\/p\u003e \u003cp\u003e1.2.1.2 Thiol–Yne Radical Click Reaction 14\u003c\/p\u003e \u003cp\u003e1.2.2 Nucleophilic Addition Click Reactions ofThiols 15\u003c\/p\u003e \u003cp\u003e1.2.2.1 Thiol–Epoxide Click Reactions 17\u003c\/p\u003e \u003cp\u003e1.2.2.2 Thiol–Isocyanate Click Reactions 17\u003c\/p\u003e \u003cp\u003e1.2.2.3 Thiol–Michael Addition Click Reactions 18\u003c\/p\u003e \u003cp\u003e1.2.2.4 Thiol–Halogen Nucleophilic Substitution Reaction 20\u003c\/p\u003e \u003cp\u003e1.3 Miscellaneous Click Reactions 21\u003c\/p\u003e \u003cp\u003eReferences 22\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Applications of Click Chemistry in Drug Discovery and Development 25\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eBalasubramanian Gopalan and Kalpattu Kuppusamy Balasubramanian\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 25\u003c\/p\u003e \u003cp\u003e2.2 Part A: Application of Click Chemistry to Drug Discovery and Development 25\u003c\/p\u003e \u003cp\u003e2.2.1 Carbonic Anhydrase Inhibitors 30\u003c\/p\u003e \u003cp\u003e2.2.2 Targeting Onchocerca Volvulus Chitinase-1 (OvCHT1) using the Hydroxytriazole Moiety within a Scaffold Hopping Approach 32\u003c\/p\u003e \u003cp\u003e2.2.3 1,2,3-Triaole-Derived Anticancer Agents 34\u003c\/p\u003e \u003cp\u003e2.2.3.1 Topoisomerase II Inhibitors 34\u003c\/p\u003e \u003cp\u003e2.2.3.2 Histone Deacetylase Inhibitors 36\u003c\/p\u003e \u003cp\u003e2.2.3.3 Protein Tyrosine Kinase Inhibitors 38\u003c\/p\u003e \u003cp\u003e2.2.3.4 Antimicrotubule Agents 39\u003c\/p\u003e \u003cp\u003e2.2.3.5 HSP 90 Inhibitors 40\u003c\/p\u003e \u003cp\u003e2.2.3.6 Autophagy-Dependent Apoptosis in CancerTherapy 41\u003c\/p\u003e \u003cp\u003e2.2.3.7 Anticancer Activity of 4β-Triazole-Podophyllotoxin 42\u003c\/p\u003e \u003cp\u003e2.2.3.8 1,2,3-Triazole-Substituted Oleanolic Acid Derivatives as Anticancer Agents 42\u003c\/p\u003e \u003cp\u003e2.2.3.9 Anti-Infective Agents 43\u003c\/p\u003e \u003cp\u003e2.2.3.10 1,2,3-Triazole Nucleoside 44\u003c\/p\u003e \u003cp\u003e2.2.3.11 1,2,3-Triazole Carbonucleosides 45\u003c\/p\u003e \u003cp\u003e2.2.3.12 β-Lactamase Inhibitors as Antibacterial Agents 47\u003c\/p\u003e \u003cp\u003e2.2.3.13 1,2,3-Triazole-Linked Carbazoles as Antitubercular Agents 48\u003c\/p\u003e \u003cp\u003e2.2.3.14 1,4-Diaryl-Substituted 1,2,3-Traizoles as Antimycobacterial (Mtb) Agents 48\u003c\/p\u003e \u003cp\u003e2.2.3.15 1,2,3-Triazole-Adamantylacetamide Hybrids as Antitubercular Agents 50\u003c\/p\u003e \u003cp\u003e2.2.3.16 Non-Nucleoside HIV Integrase Inhibitors 50\u003c\/p\u003e \u003cp\u003e2.2.3.17 MiscellaneousTherapeutic Segments: 1,2,3-Triazole-Linked Dopamine D3 Receptor (D3R) 53\u003c\/p\u003e \u003cp\u003e2.2.3.18 Peptidomimetics: 1,2,3-Triazole as a Disulfide Bond Mimetic 53\u003c\/p\u003e \u003cp\u003e2.3 Part B: Synthesis of Triazole-Based Drugs Currently in use 54\u003c\/p\u003e \u003cp\u003e2.2.1 Tazobactam 54\u003c\/p\u003e \u003cp\u003e2.3.1.1 Synthesis of tazobactam from intermediate 102 55\u003c\/p\u003e \u003cp\u003e2.3.1.2 Other reports on Tazobactam synthesis 55\u003c\/p\u003e \u003cp\u003e2.3.2 Solithromycin 56\u003c\/p\u003e \u003cp\u003e2.3.2.1 Synthesis of Solithromycin 57\u003c\/p\u003e \u003cp\u003e2.3.3 Cefatrizine 60\u003c\/p\u003e \u003cp\u003e2.3.4 Radezolid 61\u003c\/p\u003e \u003cp\u003e2.3.5 Molidustat 63\u003c\/p\u003e \u003cp\u003e2.3.5.1 Synthesis of Molidustat 63\u003c\/p\u003e \u003cp\u003e2.3.6 Tradipitant 63\u003c\/p\u003e \u003cp\u003e2.3.7 Carboxyamidotriazole 66\u003c\/p\u003e \u003cp\u003e2.3.8 Rufinamide 66\u003c\/p\u003e \u003cp\u003e2.3.8.1 Rufinamide–Novartis Process 66\u003c\/p\u003e \u003cp\u003e2.3.8.2 An Efficient Synthesis of Rufinamide 68\u003c\/p\u003e \u003cp\u003e2.3.8.3 Continuous-Flow Total Synthesis of Rufinamide 68\u003c\/p\u003e \u003cp\u003eReferences 70\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Green Chemical Synthesis and Click Reactions 77\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMaria José Arévalo, Óscar López, and Maria Victoria Gil\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 77\u003c\/p\u003e \u003cp\u003e3.2 Huisgen 1,3-Dipolar Cycloaddition 77\u003c\/p\u003e \u003cp\u003e3.2.1 Green Perspectives on Reaction Conditions 78\u003c\/p\u003e \u003cp\u003e3.2.1.1 Copper(I) Catalysts 78\u003c\/p\u003e \u003cp\u003e3.2.1.2 Copper(I) Complexes with Nitrogen- and Phosphorous-Donating Ligands 79\u003c\/p\u003e \u003cp\u003e3.2.1.3 Metalated Reagents as Catalysts 82\u003c\/p\u003e \u003cp\u003e3.2.1.4 Immobilized Copper Species 82\u003c\/p\u003e \u003cp\u003e3.2.1.5 Copper Nanocatalysis 83\u003c\/p\u003e \u003cp\u003e3.2.1.6 Other Metals as Catalysts 84\u003c\/p\u003e \u003cp\u003e3.2.1.7 Nonconventional Energy Sources 85\u003c\/p\u003e \u003cp\u003e3.2.2 Applications to Synthesis 85\u003c\/p\u003e \u003cp\u003e3.2.2.1 Regioselectivity of the Alkyne–Azide Cycloaddition 85\u003c\/p\u003e \u003cp\u003e3.2.2.2 Different Substitution Patterns on Triazole 86\u003c\/p\u003e \u003cp\u003e3.2.2.3 Strain-Promoted Cycloadditions 87\u003c\/p\u003e \u003cp\u003e3.2.2.4 Sulfonyl Azides in Huisgen Cycloaddition 87\u003c\/p\u003e \u003cp\u003e3.2.2.5 Synthesis of Vinyl-1,2,3-Triazoless 87\u003c\/p\u003e \u003cp\u003e3.2.2.6 Triazole Derivative Ligands for Coordination Chemistry 88\u003c\/p\u003e \u003cp\u003e3.2.2.7 Tetrazole Synthesis 88\u003c\/p\u003e \u003cp\u003e3.2.2.8 Synthesis of Chiral Triazoles 88\u003c\/p\u003e \u003cp\u003e3.2.2.9 Synthesis of Triazoles with Luminescent Properties 89\u003c\/p\u003e \u003cp\u003e3.2.2.10 Synthesis of Triazole Libraries 89\u003c\/p\u003e \u003cp\u003e3.2.2.11 Synthesis of Phosphorylated Triazoles 89\u003c\/p\u003e \u003cp\u003e3.3 Other 1,3-Dipolar Cycloadditions 90\u003c\/p\u003e \u003cp\u003e3.4 Atom Economy and Simplicity of Procedures in Multicomponent Reactions 90\u003c\/p\u003e \u003cp\u003e3.4.1 Reaction Conditions 91\u003c\/p\u003e \u003cp\u003e3.4.1.1 Copper Compounds as Catalysts 91\u003c\/p\u003e \u003cp\u003e3.4.1.2 Copper Complexes with Nitrogen- and Phosphorous-Donating Ligands 91\u003c\/p\u003e \u003cp\u003e3.4.1.3 Immobilized Copper Species 91\u003c\/p\u003e \u003cp\u003e3.4.1.4 Copper Nanocatalysis 92\u003c\/p\u003e \u003cp\u003e3.5 Summary and Conclusions 92\u003c\/p\u003e \u003cp\u003eReferences 93\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Synthesis of Substituted 1,2,3-Triazoles through Organocatalysis 99\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eKengadarane Anebouselvy and Dhevalapally B. Ramachary\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 99\u003c\/p\u003e \u003cp\u003e4.2 Preformed-Enolate-Based Synthesis of Substituted 1,2,3-Triazoles 101\u003c\/p\u003e \u003cp\u003e4.3 Preformed-Enamine-Based Synthesis of Substituted 1,2,3-Triazoles 106\u003c\/p\u003e \u003cp\u003e4.4 Synthesis of Substituted 1,2,3-Triazoles via Catalytic Enolate Intermediates 109\u003c\/p\u003e \u003cp\u003e4.5 General Mechanistic Aspects of Enolate Route 113\u003c\/p\u003e \u003cp\u003e4.6 Synthesis of Substituted 1,2,3-Triazoles via Enamine Intermediates 114\u003c\/p\u003e \u003cp\u003e4.7 General Mechanistic Aspects of Enamine Route 123\u003c\/p\u003e \u003cp\u003e4.8 Synthesis of Substituted 1,2,3-Triazoles via Iminium Intermediate 123\u003c\/p\u003e \u003cp\u003e4.9 Miscellaneous Routes for the Synthesis of 1,2,3-Triazoles 124\u003c\/p\u003e \u003cp\u003e4.10 Conclusions 136\u003c\/p\u003e \u003cp\u003eAcknowledgments 136\u003c\/p\u003e \u003cp\u003eReferences 137\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Applications of the Cu-Catalyzed Azide–Alkyne Cycloaddition (CuAAC) in Peptides 141\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eFreek A. B. M. Hoogstede and Floris P. J. T. Rutjes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 141\u003c\/p\u003e \u003cp\u003e5.2 CuAAC-Mediated Peptide Conjugation Strategies 142\u003c\/p\u003e \u003cp\u003e5.3 CuAAC-Mediated Peptide Backbone Modification Strategies 148\u003c\/p\u003e \u003cp\u003e5.4 Conclusions 157\u003c\/p\u003e \u003cp\u003eReferences 157\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Synthesis of Diverse Carbohydrate-Based Molecules using Click Chemistry 161\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAnoop S. Singh, Kunj B.Mishra, AmritaMishra, and Vinod K. Tiwari\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 161\u003c\/p\u003e \u003cp\u003e6.2 Cu-Catalyzed Click Chemistry in the Synthesis of Diverse Glycoconjugates 162\u003c\/p\u003e \u003cp\u003e6.3 Synthesis of Carbohydrate-Based Simple to Complex Macrocycles 181\u003c\/p\u003e \u003cp\u003e6.4 Click-Inspired Synthesis of Diverse Neoglycoconjugates 185\u003c\/p\u003e \u003cp\u003e6.5 Conclusion and Future Perspective 195\u003c\/p\u003e \u003cp\u003eAcknowledgment 196\u003c\/p\u003e \u003cp\u003eReferences 196\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Azide–Alkyne Click Reaction in Polymer Science 203\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJoydeb Mandal and S. Ramakrishnan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 203\u003c\/p\u003e \u003cp\u003e7.2 Linear, Dendritic, and Hyperbranched Polymers 205\u003c\/p\u003e \u003cp\u003e7.3 Telechelic and Block Copolymers 220\u003c\/p\u003e \u003cp\u003e7.4 Star and Star-Block Polymers 226\u003c\/p\u003e \u003cp\u003e7.5 Cyclic Polymers 230\u003c\/p\u003e \u003cp\u003e7.6 Side-Chain Clickable Polymers 235\u003c\/p\u003e \u003cp\u003e7.7 Cross-linked Polymeric Systems 238\u003c\/p\u003e \u003cp\u003e7.8 Porous Organic Polymers 242\u003c\/p\u003e \u003cp\u003e7.9 Surface Modification using CuAAC Reaction 244\u003c\/p\u003e \u003cp\u003e7.10 Strain-Promoted Click Reaction 247\u003c\/p\u003e \u003cp\u003e7.11 Topochemical Azide–Alkyne Cycloaddition (TAAC) Reactions 249\u003c\/p\u003e \u003cp\u003e7.12 Summary and Outlook 251\u003c\/p\u003e \u003cp\u003eReferences 251\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Thiol-Based “Click” Chemistry for Macromolecular Architecture Design 255\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eWeidong Zhang, Kui Chen, and Gaojian Chen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 255\u003c\/p\u003e \u003cp\u003e8.2 Thiol Chemistry for Macromolecular Architecture Design 256\u003c\/p\u003e \u003cp\u003e8.2.1 Linear Polymers 256\u003c\/p\u003e \u003cp\u003e8.2.2 Graft and Comb Polymers 258\u003c\/p\u003e \u003cp\u003e8.2.3 Star Polymers 261\u003c\/p\u003e \u003cp\u003e8.2.4 Cyclic Polymers 263\u003c\/p\u003e \u003cp\u003e8.2.5 Dendritic and Hyperbranched Polymers 265\u003c\/p\u003e \u003cp\u003e8.2.6 Conjugated and Hybrid Polymers 270\u003c\/p\u003e \u003cp\u003e8.3 Conclusion 276\u003c\/p\u003e \u003cp\u003eAcknowledgments 284\u003c\/p\u003e \u003cp\u003eReferences 284\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Synthesis of Macrocycles and Click Chemistry 287\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eDario Pasini\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 287\u003c\/p\u003e \u003cp\u003e9.1.1 Peptide- and Sugar-Containing Click Macrocycles 289\u003c\/p\u003e \u003cp\u003e9.1.2 Click Macrocycles for Anion Binding and Supramolecular Recognition 297\u003c\/p\u003e \u003cp\u003e9.1.3 Clicking Macrocycles to form Mechanical Bonds 300\u003c\/p\u003e \u003cp\u003e9.1.4 Cyclic Polymers Obtained by the CuAAC Click Reaction 302\u003c\/p\u003e \u003cp\u003e9.2 Summary and Conclusions 304\u003c\/p\u003e \u003cp\u003eReferences 304\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Modifications of Nucleosides, Nucleotides, and Nucleic Acids using Huisgen’s [3+2] Azide–Alkyne Cycloaddition: Opening Pandora’s Box 309\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eFranck Amblard, Ozkan Sari, Sebastien Boucle, Ahmed Khalil, and Raymond F. Schinazi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 309\u003c\/p\u003e \u003cp\u003e10.1.1 Nucleoside Modifications 309\u003c\/p\u003e \u003cp\u003e10.1.1.1 Nucleoside Analogs as Potential Drugs 309\u003c\/p\u003e \u003cp\u003e10.1.1.2 Nucleoside Bioconjugates 311\u003c\/p\u003e \u003cp\u003e10.2 Nucleotide and Nucleic Acid Modifications 316\u003c\/p\u003e \u003cp\u003e10.2.1 “Artificial” DNA 316\u003c\/p\u003e \u003cp\u003e10.2.2 Presynthetic Modification DNA 316\u003c\/p\u003e \u003cp\u003e10.2.3 Postsynthetic Modification 318\u003c\/p\u003e \u003cp\u003e10.3 Conclusion 331\u003c\/p\u003e \u003cp\u003eAcknowledgments 332\u003c\/p\u003e \u003cp\u003eReferences 332\u003c\/p\u003e \u003cp\u003eIndex 337\u003c\/p\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":48743119356247,"sku":"9783527339167","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"c-h-activation-for-asymmetric-synthesis-9783527343409","title":"C-H Activation for Asymmetric Synthesis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eProvides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry \u003cbr\u003e  \u003cbr\u003e Written by leading international authors in the field, this book introduces readers to C-H activation in asymmetric synthesis along with all of its facets. It presents stereoselective C-H functionalization with a broad coverage, from outer-sphere to inner-sphere C-H bond activation, and from the control of olefin geometry to the induction of point, planar and axial chirality. Moreover, methods wherein asymmetry is introduced either during the C-H activation or in a different elementary step are discussed.  \u003cbr\u003e  \u003cbr\u003e Presented in two parts?asymmetric activation of C(sp3)-H bonds and stereoselective synthesis implying activation of C(sp2)-H bonds?CH-Activation for Asymmetric Synthesis showcases the diversity of stereogenic elements, which can now be constructed by C-H activation methods. Chapters in Part 1 cover: C(sp3)-H bond insertion by metal carbenoids and nitrenoids; stereoselective C-C bond and C-N bond forming reactions through C(sp3)?H bond insertion of metal nitrenoids; enantioselective intra- and intermolecular couplings; and more. Part 2 looks at: C-H activation involved in stereodiscriminant step; planar chirality; diastereoselective formation of alkenes through C(sp2)?H bond activation; amongst other methods.  \u003cbr\u003e  \u003cbr\u003e -Covers one of the most rapidly developing fields in organic synthesis and catalysis \u003cbr\u003e -Clearly structured in two parts (activation of sp3- and activation of sp2-H bonds) \u003cbr\u003e -Edited by two leading experts in C-H activation in asymmetric synthesis  \u003cbr\u003e  \u003cbr\u003e CH-Activation for Asymmetric Synthesis will be of high interest to chemists in academia, as well as those in the pharmaceutical and agrochemical industry. \u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Asymmetric Activation of C(sp\u003csup\u003e3\u003c\/sup\u003e)—H Bonds \u003c\/b\u003e\u003cb\u003e1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I.A C(sp\u003csup\u003e3\u003c\/sup\u003e)—H Bond Insertion by Metal Carbenoids and Nitrenoids \u003c\/b\u003e\u003cb\u003e2\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Stereoselective C—C Bond-Forming Reactions Through C(sp\u003csup\u003e3\u003c\/sup\u003e)—H Bond Insertion of Metal Carbenoids \u003c\/b\u003e\u003cb\u003e3\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAoife M. Buckley, Thomas A. Brouder, Alan Ford, and Anita R. Maguire\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 3\u003c\/p\u003e \u003cp\u003e1.2 Diazo Compounds 4\u003c\/p\u003e \u003cp\u003e1.3 Mechanistic Understanding 5\u003c\/p\u003e \u003cp\u003e1.4 Catalysts 7\u003c\/p\u003e \u003cp\u003e1.4.1 Copper 7\u003c\/p\u003e \u003cp\u003e1.4.1.1 Bisoxazoline and Schiff Base 7\u003c\/p\u003e \u003cp\u003e1.4.2 Rhodium 8\u003c\/p\u003e \u003cp\u003e1.4.2.1 Rhodium(II) Carboxylates 9\u003c\/p\u003e \u003cp\u003e1.4.2.2 Rhodium(II) Carboxamidates 10\u003c\/p\u003e \u003cp\u003e1.4.2.3 Ortho-metalated Complexes 11\u003c\/p\u003e \u003cp\u003e1.4.3 Iridium and Ruthenium 11\u003c\/p\u003e \u003cp\u003e1.5 Intramolecular C(sp\u003csup\u003e3\u003c\/sup\u003e)—H Bond Insertion 11\u003c\/p\u003e \u003cp\u003e1.5.1 Chemoselectivity 13\u003c\/p\u003e \u003cp\u003e1.5.1.1 Catalyst Effects 13\u003c\/p\u003e \u003cp\u003e1.5.1.2 Substrate Effects 14\u003c\/p\u003e \u003cp\u003e1.5.2 Regioselectivity 16\u003c\/p\u003e \u003cp\u003e1.5.2.1 Formation of Three-Membered Rings 17\u003c\/p\u003e \u003cp\u003e1.5.2.2 Formation of Four-Membered Rings 18\u003c\/p\u003e \u003cp\u003e1.5.2.3 Formation of Five-Membered Rings 20\u003c\/p\u003e \u003cp\u003e1.5.2.4 Formation of Six-Membered Rings 20\u003c\/p\u003e \u003cp\u003e1.5.3 Diastereoselectivity 23\u003c\/p\u003e \u003cp\u003e1.5.3.1 Substrate Effects 23\u003c\/p\u003e \u003cp\u003e1.5.3.2 Catalyst Effects 25\u003c\/p\u003e \u003cp\u003e1.5.4 Enantioselectivity 25\u003c\/p\u003e \u003cp\u003e1.6 Intermolecular C(sp\u003csup\u003e3\u003c\/sup\u003e)—H Bond Insertion 30\u003c\/p\u003e \u003cp\u003e1.6.1 Chemoselectivity 30\u003c\/p\u003e \u003cp\u003e1.6.1.1 Diazo Compounds 32\u003c\/p\u003e \u003cp\u003e1.6.1.2 Catalyst Effects 34\u003c\/p\u003e \u003cp\u003e1.6.1.3 Substrate Functional Groups 35\u003c\/p\u003e \u003cp\u003e1.6.2 Regioselectivity 36\u003c\/p\u003e \u003cp\u003e1.6.2.1 Substrate Effects 36\u003c\/p\u003e \u003cp\u003e1.6.2.2 Catalyst Effects 38\u003c\/p\u003e \u003cp\u003e1.6.2.3 Diazo Compound Effects 39\u003c\/p\u003e \u003cp\u003e1.6.3 Diastereoselectivity 39\u003c\/p\u003e \u003cp\u003e1.6.3.1 Substrate Effects 39\u003c\/p\u003e \u003cp\u003e1.6.3.2 Catalyst Effects 42\u003c\/p\u003e \u003cp\u003e1.6.4 Enantioselectivity 43\u003c\/p\u003e \u003cp\u003e1.7 Conclusion 45\u003c\/p\u003e \u003cp\u003eReferences 45\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Stereoselective C—N Bond-Forming Reactions Through C(sp\u003csup\u003e3\u003c\/sup\u003e)—H Bond Insertion of Metal Nitrenoids \u003c\/b\u003e\u003cb\u003e51\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePhilippe Dauban, Romain Rey-Rodriguez, and Ali Nasrallah\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 51\u003c\/p\u003e \u003cp\u003e2.2 Historical Background 52\u003c\/p\u003e \u003cp\u003e2.2.1 Seminal Studies in Catalytic C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Amination 52\u003c\/p\u003e \u003cp\u003e2.2.2 Mechanistic and Stereochemical Issues 56\u003c\/p\u003e \u003cp\u003e2.3 Catalytic Stereoselective C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Amination Reactions with Iminoiodinanes 60\u003c\/p\u003e \u003cp\u003e2.3.1 Catalytic Intermolecular Enantioselective Reactions (Chirality Only on the Metal Complex) 60\u003c\/p\u003e \u003cp\u003e2.3.2 Catalytic Intramolecular Enantioselective Reactions 63\u003c\/p\u003e \u003cp\u003e2.3.3 Catalytic Intermolecular Diastereoselective Reactions (Chirality on the Metal Complex and the Nitrene Precursor) 66\u003c\/p\u003e \u003cp\u003e2.4 Catalytic Stereoselective C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Amination Reactions with Azides 67\u003c\/p\u003e \u003cp\u003e2.4.1 Transition Metal-Catalyzed C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Amination Reactions 67\u003c\/p\u003e \u003cp\u003e2.4.2 Enzymatic C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Amination Reactions 68\u003c\/p\u003e \u003cp\u003e2.5 Catalytic Stereoselective C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Amination Reactions with\u003ci\u003e N\u003c\/i\u003e-(Sulfonyloxy)carbamates 70\u003c\/p\u003e \u003cp\u003e2.6 Conclusion 72\u003c\/p\u003e \u003cp\u003eReferences 72\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I.B C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Activation as Stereodiscriminant Step \u003c\/b\u003e\u003cb\u003e77\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Enantioselective Intra- and Intermolecular Couplings \u003c\/b\u003e\u003cb\u003e79\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eQiaoqiao Teng and Wei-Liang Duan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 79\u003c\/p\u003e \u003cp\u003e3.2 Enantioselective Intramolecular Couplings of Aliphatic Substrates 79\u003c\/p\u003e \u003cp\u003e3.2.1 C–C Coupling 79\u003c\/p\u003e \u003cp\u003e3.2.2 C–X Coupling 89\u003c\/p\u003e \u003cp\u003e3.3 Enantioselective Intermolecular Couplings of Aliphatic Substrates 90\u003c\/p\u003e \u003cp\u003e3.3.1 Pd Catalysis 91\u003c\/p\u003e \u003cp\u003e3.3.2 Rh Catalysis 102\u003c\/p\u003e \u003cp\u003e3.3.3 Ir Catalysis 102\u003c\/p\u003e \u003cp\u003e3.4 Conclusion 104\u003c\/p\u003e \u003cp\u003eReferences 105\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Substrate-Controlled Transformation: Diastereoselective Functionalization \u003c\/b\u003e\u003cb\u003e107\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSheng-Yi Yan, Bin Liu, and Bing-Feng Shi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 107\u003c\/p\u003e \u003cp\u003e4.2 Diastereoselective Functionalizations of\u003ci\u003e N\u003c\/i\u003e-Phthaloyl-α-Amino Acids 108\u003c\/p\u003e \u003cp\u003e4.2.1 Diastereoselective β-C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Functionalizations of \u003ci\u003eN\u003c\/i\u003e-Phthaloyl-α-Amino Acids 108\u003c\/p\u003e \u003cp\u003e4.2.1.1 Bidentate Directing Group 108\u003c\/p\u003e \u003cp\u003e4.2.1.2 Monodentate Directing Group 114\u003c\/p\u003e \u003cp\u003e4.2.2 Diastereoselective γ-C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Functionalization of α-Amino Acid Derivatives 114\u003c\/p\u003e \u003cp\u003e4.3 Diastereoselective C–H Activation Controlled by Chiral Auxiliary 116\u003c\/p\u003e \u003cp\u003e4.4 Diastereoselective C(sp\u003csup\u003e3\u003c\/sup\u003e)–H Functionalization of Conformationally Restricted Cyclic Substrates 121\u003c\/p\u003e \u003cp\u003e4.5 Summary and Conclusions 127\u003c\/p\u003e \u003cp\u003eReferences 128\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Stereoselective Synthesis Implying Activation of C(sp\u003csup\u003e2\u003c\/sup\u003e)—H Bonds \u003c\/b\u003e\u003cb\u003e131\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Planar Chirality via C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Activation Involved in Stereodiscriminant Step \u003c\/b\u003e\u003cb\u003e133\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eQing Gu and Shu-Li You\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 133\u003c\/p\u003e \u003cp\u003e5.2 Diastereoselective Synthesis of Planar Chiral Ferrocenes 134\u003c\/p\u003e \u003cp\u003e5.3 Enantioselective Synthesis of Planar Chiral Ferrocenes 134\u003c\/p\u003e \u003cp\u003e5.3.1 Pd(II)-Catalyzed Direct C—H Bond Functionalization 134\u003c\/p\u003e \u003cp\u003e5.3.2 Pd(0)-Catalyzed Direct C—H Bond Functionalization 140\u003c\/p\u003e \u003cp\u003e5.3.3 Ir\/Rh-Catalyzed Direct C—H Bond Functionalization 144\u003c\/p\u003e \u003cp\u003e5.3.4 Au\/Pt-Catalyzed Direct C—H Bond Functionalization 146\u003c\/p\u003e \u003cp\u003e5.4 Conclusion 147\u003c\/p\u003e \u003cp\u003eReferences 148\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Axial Chirality via C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Activation Involved in Stereodiscriminant Step \u003c\/b\u003e\u003cb\u003e151\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eQuentin Dherbassy, Joanna Wencel-Delord, and Françoise Colobert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 151\u003c\/p\u003e \u003cp\u003e6.2 Asymmetric Coupling of Two Arenes by Oxidative Dimerization 152\u003c\/p\u003e \u003cp\u003e6.2.1 Copper-Catalyzed Reactions 153\u003c\/p\u003e \u003cp\u003e6.2.2 Vanadium-Catalyzed Reactions 154\u003c\/p\u003e \u003cp\u003e6.2.3 Iron-Catalyzed Reactions 155\u003c\/p\u003e \u003cp\u003e6.2.4 Application in the Synthesis of Natural Products 155\u003c\/p\u003e \u003cp\u003e6.2.5 Conclusion 156\u003c\/p\u003e \u003cp\u003e6.3 Stereoselective C–H Functionalization of Prochiral or Racemic Biaryls 158\u003c\/p\u003e \u003cp\u003e6.3.1 Asymmetric C–H Alkylation of Naphthylpyridines 158\u003c\/p\u003e \u003cp\u003e6.3.2 Diastereoselective C–H Functionalization Using a Chiral Directing Group 159\u003c\/p\u003e \u003cp\u003e6.3.2.1 Sulfinyl as Chiral Directing Group 159\u003c\/p\u003e \u003cp\u003e6.3.2.2 Phosphates as Chiral Directing Group 162\u003c\/p\u003e \u003cp\u003e6.3.3 Enantioselective C–H Functionalization of Racemic Biaryl 163\u003c\/p\u003e \u003cp\u003e6.3.4 Stereoselective C–H Functionalization Using a Transient Chiral Directing Group 165\u003c\/p\u003e \u003cp\u003e6.3.5 Conclusion 167\u003c\/p\u003e \u003cp\u003e6.4 Atroposelective Cross-Coupling of Two Moieties 167\u003c\/p\u003e \u003cp\u003e6.4.1 Pd-Catalyzed C–H Arylation of Thiophene Derivatives 167\u003c\/p\u003e \u003cp\u003e6.4.2 Pd-Catalyzed C–H Arylation of Biaryl Sulfoxides 169\u003c\/p\u003e \u003cp\u003e6.4.3 Rh-Catalyzed C–H Arylation of Diazonaphthoquinones 171\u003c\/p\u003e \u003cp\u003e6.4.4 Conclusion 172\u003c\/p\u003e \u003cp\u003e6.5 General Conclusion 172\u003c\/p\u003e \u003cp\u003eReferences 172\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Central Chirality via Asymmetric C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Activation Implying Desymmetrization and Kinetic Resolution \u003c\/b\u003e\u003cb\u003e175\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eSoufyan Jerhaoui, Françoise Colobert, and Joanna Wencel-Delord\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Synthesis of C-Stereogenic Molecules via C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Functionalization 175\u003c\/p\u003e \u003cp\u003e7.1.1 Desymmetrization 175\u003c\/p\u003e \u003cp\u003e7.1.2 Kinetic Resolution 182\u003c\/p\u003e \u003cp\u003e7.2 Synthesis of P-Central Chiral Molecules via C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Functionalization 183\u003c\/p\u003e \u003cp\u003e7.3 Synthesis of Chiral Organosilicon Molecules via C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Functionalization 187\u003c\/p\u003e \u003cp\u003e7.4 Synthesis of S-Chiral Molecules via C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Functionalization 189\u003c\/p\u003e \u003cp\u003e7.5 Conclusions 190\u003c\/p\u003e \u003cp\u003eReferences 191\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Non-stereoselective C(sp\u003csup\u003e2\u003c\/sup\u003e)–H Activation Followed by Selective Functionalization of Metallacyclic Intermediate \u003c\/b\u003e\u003cb\u003e193\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eXiaohong Chen, Xue Gong, Bo Wang, and Guoyong Song\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 193\u003c\/p\u003e \u003cp\u003e8.2 Intramolecular Couplings 194\u003c\/p\u003e \u003cp\u003e8.2.1 Palladium and Nickel Catalysis 194\u003c\/p\u003e \u003cp\u003e8.2.2 Rhodium Catalysis 196\u003c\/p\u003e \u003cp\u003e8.2.3 Iridium Catalysis 200\u003c\/p\u003e \u003cp\u003e8.2.4 Enantioselective Hydroacylation 203\u003c\/p\u003e \u003cp\u003e8.3 Intermolecular Couplings 210\u003c\/p\u003e \u003cp\u003e8.3.1 Rhodium Catalysis 210\u003c\/p\u003e \u003cp\u003e8.3.2 Iridium Catalysis 219\u003c\/p\u003e \u003cp\u003e8.3.3 Other Metal Catalysis 226\u003c\/p\u003e \u003cp\u003e8.4 Conclusion 231\u003c\/p\u003e \u003cp\u003eAcknowledgments 231\u003c\/p\u003e \u003cp\u003eReferences 231\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Diastereoselective Formation of Alkenes Through C(sp\u003csup\u003e2\u003c\/sup\u003e)—H Bond Activation \u003c\/b\u003e\u003cb\u003e239\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eParthasarathy Gandeepan and Lutz Ackermann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 239\u003c\/p\u003e \u003cp\u003e9.2 C–H Activation with Alkenes 241\u003c\/p\u003e \u003cp\u003e9.2.1 Nondirected C–H Alkenylation 241\u003c\/p\u003e \u003cp\u003e9.2.2 Directed C–H Alkenylation 244\u003c\/p\u003e \u003cp\u003e9.3 C–H Activation with Alkenyl (Pseudo)halides 250\u003c\/p\u003e \u003cp\u003e9.4 Hydroarylation 252\u003c\/p\u003e \u003cp\u003e9.4.1 Hydroarylation of Alkynes 252\u003c\/p\u003e \u003cp\u003e9.4.2 Hydroarylation of Allenes 257\u003c\/p\u003e \u003cp\u003e9.5 Hydroacylation 261\u003c\/p\u003e \u003cp\u003e9.5.1 Hydroacylation of Alkynes 261\u003c\/p\u003e \u003cp\u003e9.5.2 Hydroacylation of Allenes 263\u003c\/p\u003e \u003cp\u003e9.6 Conclusion 264\u003c\/p\u003e \u003cp\u003eReferences 265\u003c\/p\u003e \u003cp\u003eIndex 275\u003c\/p\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":48743120240983,"sku":"9783527343409","price":108.86,"currency_code":"GBP","in_stock":false}]},{"product_id":"nickel-catalysis-in-organic-synthesis-methods-and-reactions-9783527344079","title":"Nickel Catalysis in Organic Synthesis: Methods","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eA comprehensive reference to nickel chemistry for every scientist working with organometallic catalysts \u003cbr\u003e  \u003cbr\u003e Written by one of the world?s leading reseachers in the field, Nickel Catalysis in Organic Synthesis presents a comprehensive review of  the high potential of modern nickel catalysis and its application in synthesis. Structured in a clear and assessible manner, the book offers a collection of various reaction types, such as cross-coupling reactions, reactions for the activation of unreactive bonds, carbon dioxide fixation, and many more.  \u003cbr\u003e  \u003cbr\u003e Nickel has been recognized as one of the most interesting transition metals for homogeneous catalysis. This book offers an overview to the recently developed new ligands, new reaction conditions, and new apparatus to control the reactivity of nickel catalysts, allowing scientists to apply nickel catalysts to a variety of bond-forming reactions. A must-read for anyone working with organometallic compounds and their application in organic synthesis, this important guide:  \u003cbr\u003e  \u003cbr\u003e -Reviews the numerous applications of nickel catalysis in synthesis  \u003cbr\u003e -Explores the use of nickel as a relatively cheap and earth-abundant metal \u003cbr\u003e -Examines the versatility of nickel catalysis in reactions like cross-coupling reactions and CH activations \u003cbr\u003e -Offers a resource for academics and industry professionals \u003cbr\u003e  \u003cbr\u003e Written for catalytic chemists, organic chemists, inorganic chemists, structural chemists, and chemists in industry, Nickel Catalysis in Organic Synthesis provides a much-needed overview of the most recent developments in modern nickel catalysis and its application in synthesis. \u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Reactions via Nickelacycles \u003c\/b\u003e\u003cb\u003e1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Formation of Nickelacycles and Reaction with Carbon Monoxide \u003c\/b\u003e\u003cb\u003e3\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eSensuke Ogoshi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 3\u003c\/p\u003e \u003cp\u003e1.2 Formation of Hetero-nickelacycles from Nickel(0) 3\u003c\/p\u003e \u003cp\u003e1.3 Stoichiometric Reaction of Hetero-nickelacycles with Carbon Monoxide 4\u003c\/p\u003e \u003cp\u003eReferences 9\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Transformation of Aldehydes via Nickelacycles \u003c\/b\u003e\u003cb\u003e13\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eYoichi Hoshimoto\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction and Scope ofThis Chapter 13\u003c\/p\u003e \u003cp\u003e2.2 Catalytic Transformation of Aldehydes Through Three-Membered Oxanickelacycle Complexes 14\u003c\/p\u003e \u003cp\u003e2.3 Catalytic Transformation of Aldehydes Through Five-Membered Oxanickelacycle Complexes 18\u003c\/p\u003e \u003cp\u003e2.4 Catalytic Transformation of Aldehydes Through Seven-Membered Oxanickelacycle Complexes 22\u003c\/p\u003e \u003cp\u003e2.5 Conclusion and Outlook 23\u003c\/p\u003e \u003cp\u003eReferences 25\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Transformation of Imines via Nickelacycles \u003c\/b\u003e\u003cb\u003e29\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMasato Ohashi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 29\u003c\/p\u003e \u003cp\u003e3.2 [2+2+1] Carbonylative Cycloaddition of an Imine and Either an Alkyne or an Alkene Leading to γ-Lactams 29\u003c\/p\u003e \u003cp\u003e3.3 [2+2+2] Cycloaddition Reaction of an Imine with Two Alkynes: Formation of 1,2-Dihydropyridine Derivatives 31\u003c\/p\u003e \u003cp\u003e3.4 Three-Component Coupling and Cyclocondensation Reactions of an Imine, an Alkyne, and Alkylmetal Reagents 34\u003c\/p\u003e \u003cp\u003eReferences 37\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Asymmetric C—C Bond Formation Reactions via Nickelacycles \u003c\/b\u003e\u003cb\u003e39\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRavindra Kumar and Sensuke Ogoshi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 39\u003c\/p\u003e \u003cp\u003e4.2 Enantioselective Reactions Involving Nickelacycles 39\u003c\/p\u003e \u003cp\u003e4.2.1 Nickel-Catalyzed Asymmetric Coupling of Alkynes and Aldehydes 39\u003c\/p\u003e \u003cp\u003e4.2.1.1 Nickel-Catalyzed Asymmetric Reductive Coupling of Alkynes and Aldehydes 40\u003c\/p\u003e \u003cp\u003e4.2.1.2 Nickel-Catalyzed Asymmetric Alkylative Coupling of Alkynes and Aldehydes 43\u003c\/p\u003e \u003cp\u003e4.2.2 Nickel-Catalyzed Asymmetric Coupling of Alkynes and Imines 44\u003c\/p\u003e \u003cp\u003e4.2.3 Nickel-Catalyzed Asymmetric Coupling of 1,3-Enynes and Aldehydes 45\u003c\/p\u003e \u003cp\u003e4.2.4 Nickel-Catalyzed Asymmetric Coupling of 1,3-Enynes and Ketones 46\u003c\/p\u003e \u003cp\u003e4.2.5 Nickel-Catalyzed Asymmetric Coupling of 1,3-Dienes and Aldehydes 47\u003c\/p\u003e \u003cp\u003e4.2.6 Nickel-Catalyzed Asymmetric Coupling of Enones and Alkynes 50\u003c\/p\u003e \u003cp\u003e4.2.6.1 Nickel-Catalyzed Asymmetric Alkylative Coupling of Enones and Alkynes 50\u003c\/p\u003e \u003cp\u003e4.2.6.2 Nickel-Catalyzed Asymmetric Coupling of Enones and Alkynes 51\u003c\/p\u003e \u003cp\u003e4.2.7 Nickel-Catalyzed Asymmetric Coupling of Arylenoates and Alkynes 55\u003c\/p\u003e \u003cp\u003e4.2.8 Nickel-Catalyzed Asymmetric Coupling of Diynes with Ketenes 56\u003c\/p\u003e \u003cp\u003e4.2.9 Nickel-Catalyzed Asymmetric Coupling of Allenes, Aldehydes, and Silanes 57\u003c\/p\u003e \u003cp\u003e4.2.10 Nickel-Catalyzed Asymmetric Coupling of Allenes and Isocyanates 58\u003c\/p\u003e \u003cp\u003e4.2.11 Nickel-Catalyzed Asymmetric Coupling of Alkenes, Aldehydes, and Silanes 59\u003c\/p\u003e \u003cp\u003e4.2.12 Nickel-Catalyzed Asymmetric Coupling of Formamide and Alkene 61\u003c\/p\u003e \u003cp\u003e4.2.13 Nickel-Catalyzed Asymmetric Coupling of Alkynes and Cyclopropyl Carboxamide 63\u003c\/p\u003e \u003cp\u003e4.3 Miscellaneous 64\u003c\/p\u003e \u003cp\u003e4.3.1 Nickel-Catalyzed Asymmetric Annulation of Pyridones via Hydroarylation to Alkenes 64\u003c\/p\u003e \u003cp\u003e4.3.2 Nickel-Catalyzed Asymmetric Synthesis of Benzoxasilole 65\u003c\/p\u003e \u003cp\u003e4.4 Overview and Future Perspective 66\u003c\/p\u003e \u003cp\u003eReferences 67\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Functionalization of Unreactive Bonds \u003c\/b\u003e\u003cb\u003e69\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Recent Advances in Ni-Catalyzed Chelation-Assisted Direct Functionalization of Inert C—H Bonds \u003c\/b\u003e\u003cb\u003e71\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eYan-Hua Liu, Fang Hu, and Bing-Feng Shi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 71\u003c\/p\u003e \u003cp\u003e5.2 Ni-Catalyzed Functionalization of Inert C\u003cb\u003e—\u003c\/b\u003eH Bonds Assisted by Bidentate Directing Groups 71\u003c\/p\u003e \u003cp\u003e5.2.1 Arylation 72\u003c\/p\u003e \u003cp\u003e5.2.2 Alkylation 76\u003c\/p\u003e \u003cp\u003e5.2.3 Alkenylation 83\u003c\/p\u003e \u003cp\u003e5.2.4 Alkynylation 85\u003c\/p\u003e \u003cp\u003e5.2.5 Other C—C Bond Formation Reactions Directed by Bidentate Directing Group 88\u003c\/p\u003e \u003cp\u003e5.2.6 C—N Bond Formation 89\u003c\/p\u003e \u003cp\u003e5.2.7 C–Chalcogen (Chalcogen = O, S, Se) Bond Formation 89\u003c\/p\u003e \u003cp\u003e5.2.8 C–Halogen Bond Formation 92\u003c\/p\u003e \u003cp\u003e5.3 Ni-Catalyzed Functionalization of Inert C\u003cb\u003e—\u003c\/b\u003eH Bonds Assisted by Monodentate Directing Groups 94\u003c\/p\u003e \u003cp\u003e5.3.1 Alkylation 94\u003c\/p\u003e \u003cp\u003e5.3.2 Alkenylation 95\u003c\/p\u003e \u003cp\u003e5.3.3 Alkynylation 96\u003c\/p\u003e \u003cp\u003e5.3.4 C–Calcogen Bond Formation 97\u003c\/p\u003e \u003cp\u003e5.4 Summary 98\u003c\/p\u003e \u003cp\u003eReferences 98\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 C—C Bond Functionalization \u003c\/b\u003e\u003cb\u003e103\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eYoshiaki Nakao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 103\u003c\/p\u003e \u003cp\u003e6.2 C—C Bond Functionalization of Three-Membered Rings 103\u003c\/p\u003e \u003cp\u003e6.3 C—C Bond Functionalization of Four- and Five-Membered Rings 110\u003c\/p\u003e \u003cp\u003e6.4 C—C Bond Functionalization of Less Strained Molecules 113\u003c\/p\u003e \u003cp\u003e6.5 C—CN Bond Functionalization 115\u003c\/p\u003e \u003cp\u003e6.6 Summary and Outlook 116\u003c\/p\u003e \u003cp\u003eReferences 117\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 C—O Bond Transformations \u003c\/b\u003e\u003cb\u003e123\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMamoru Tobisu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 123\u003c\/p\u003e \u003cp\u003e7.2 C(aryl)—O Bond Cleavage 124\u003c\/p\u003e \u003cp\u003e7.2.1 Aryl Esters, Carbamates, and Carbonates 124\u003c\/p\u003e \u003cp\u003e7.2.2 Aryl Ethers 132\u003c\/p\u003e \u003cp\u003e7.2.3 Arenols 136\u003c\/p\u003e \u003cp\u003e7.3 C(benzyl)—O Bond Cleavage 138\u003c\/p\u003e \u003cp\u003e7.3.1 Benzyl Esters and Carbamates 138\u003c\/p\u003e \u003cp\u003e7.3.2 Benzyl Ethers 140\u003c\/p\u003e \u003cp\u003e7.4 C(acyl)—O Bond Cleavage 141\u003c\/p\u003e \u003cp\u003e7.5 Summary and Outlook 144\u003c\/p\u003e \u003cp\u003eReferences 145\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Coupling Reactions via Ni(I) and\/or Ni(III) \u003c\/b\u003e\u003cb\u003e151\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Photo-Assisted Nickel-Catalyzed Cross-Coupling Processes \u003c\/b\u003e\u003cb\u003e153\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eChristophe Lévêque, Cyril Ollivier, and Louis Fensterbank\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 153\u003c\/p\u003e \u003cp\u003e8.2 Development of Visible-Light Photoredox\/Nickel Dual Catalysis 154\u003c\/p\u003e \u003cp\u003e8.2.1 For the Formation of Carbon–Carbon Bonds 154\u003c\/p\u003e \u003cp\u003e8.2.1.1 Starting from Organotrifluoroborates 154\u003c\/p\u003e \u003cp\u003e8.2.1.2 Starting from Carboxylates or Keto Acids or from Methylanilines 157\u003c\/p\u003e \u003cp\u003e8.2.1.3 Starting from Alkylsilicates 160\u003c\/p\u003e \u003cp\u003e8.2.1.4 Starting from 1,4-Dihydropyridines 166\u003c\/p\u003e \u003cp\u003e8.2.1.5 Starting from Alkylsulfinates 168\u003c\/p\u003e \u003cp\u003e8.2.1.6 Starting from Alkyl Bromides 168\u003c\/p\u003e \u003cp\u003e8.2.1.7 Starting from Xanthates 169\u003c\/p\u003e \u003cp\u003e8.2.1.8 Starting from Sp\u003csup\u003e3\u003c\/sup\u003e CH Bonds 169\u003c\/p\u003e \u003cp\u003e8.2.2 For the Formation of Carbon–Heteroatom Bonds 170\u003c\/p\u003e \u003cp\u003e8.2.2.1 Formation of C—O Bond 170\u003c\/p\u003e \u003cp\u003e8.2.2.2 Formation of C—P Bond 171\u003c\/p\u003e \u003cp\u003e8.2.2.3 Formation of C—S Bond 171\u003c\/p\u003e \u003cp\u003e8.3 Energy-Transfer-Mediated Nickel Catalysis 173\u003c\/p\u003e \u003cp\u003e8.4 Conclusion 175\u003c\/p\u003e \u003cp\u003eReferences 176\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Cross-Electrophile Coupling: Principles and New Reactions \u003c\/b\u003e\u003cb\u003e183\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMatthew M. Goldfogel, Liangbin Huang, and Daniel J. Weix\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 183\u003c\/p\u003e \u003cp\u003e9.2 Mechanistic Discussion of Cross-Electrophile Coupling 185\u003c\/p\u003e \u003cp\u003e9.3 C(sp\u003csup\u003e2\u003c\/sup\u003e)—C(sp\u003csup\u003e3\u003c\/sup\u003e) Bond Formation 188\u003c\/p\u003e \u003cp\u003e9.3.1 Cross-Electrophile Coupling of Aryl-X and Alkyl-X 188\u003c\/p\u003e \u003cp\u003e9.3.2 Cross-Electrophile Coupling of ArX and Bn-X 195\u003c\/p\u003e \u003cp\u003e9.3.3 Cross-Electrophile Coupling of ArX and Allyl-X 196\u003c\/p\u003e \u003cp\u003e9.3.4 Vinyl-X with R-X 197\u003c\/p\u003e \u003cp\u003e9.3.5 Acyl-X with Alkyl-X 199\u003c\/p\u003e \u003cp\u003e9.4 C(sp\u003csup\u003e2\u003c\/sup\u003e)–C(sp\u003csup\u003e2\u003c\/sup\u003e) Coupling 201\u003c\/p\u003e \u003cp\u003e9.4.1 Aryl-X\/Vinyl-X+Aryl-X\/Vinyl-X 201\u003c\/p\u003e \u003cp\u003e9.4.2 Aryl-X+Acyl-X 202\u003c\/p\u003e \u003cp\u003e9.5 C(sp\u003csup\u003e3\u003c\/sup\u003e)–C(sp\u003csup\u003e3\u003c\/sup\u003e) Coupling 203\u003c\/p\u003e \u003cp\u003e9.6 C(sp)–C(sp\u003csup\u003e3\u003c\/sup\u003e) Coupling 205\u003c\/p\u003e \u003cp\u003e9.7 Multicomponent Reactions 206\u003c\/p\u003e \u003cp\u003e9.8 Future of the Field 208\u003c\/p\u003e \u003cp\u003eReferences 209\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Organometallic Chemistry of High-Valent Ni(III) and Ni(IV) Complexes \u003c\/b\u003e\u003cb\u003e223\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eLiviu M. Mirica, Sofia M. Smith, and Leonel Griego\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 223\u003c\/p\u003e \u003cp\u003e10.2 Organometallic Ni(III) Complexes 223\u003c\/p\u003e \u003cp\u003e10.3 Organometallic Ni(IV) Complexes 234\u003c\/p\u003e \u003cp\u003e10.4 Other High-Valent Ni Complexes 239\u003c\/p\u003e \u003cp\u003e10.4.1 Additional Ni\u003csup\u003eIII\u003c\/sup\u003e Complexes 239\u003c\/p\u003e \u003cp\u003e10.4.2 Additional Ni\u003csup\u003eIV \u003c\/sup\u003eComplexes 241\u003c\/p\u003e \u003cp\u003e10.5 Conclusions and Outlook 243\u003c\/p\u003e \u003cp\u003eReferences 244\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Carbon Dioxide Fixation \u003c\/b\u003e\u003cb\u003e249\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Carbon Dioxide Fixation via Nickelacycle \u003c\/b\u003e\u003cb\u003e251\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRyohei Doi and Yoshihiro Sato\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction: Carbon Dioxide as a C1 Building Block 251\u003c\/p\u003e \u003cp\u003e11.2 Formation, Structure, and Reactivity of Nickelalactone 252\u003c\/p\u003e \u003cp\u003e11.2.1 Formation and Characterization of Nickelalactone via Oxidative Cyclization with CO\u003csub\u003e2\u003c\/sub\u003e 252\u003c\/p\u003e \u003cp\u003e11.2.1.1 Reaction with Alkene 252\u003c\/p\u003e \u003cp\u003e11.2.1.2 Reaction with Allene 255\u003c\/p\u003e \u003cp\u003e11.2.1.3 Reaction with Diene 256\u003c\/p\u003e \u003cp\u003e11.2.1.4 Reaction with Alkyne 257\u003c\/p\u003e \u003cp\u003e11.2.1.5 Other Related Reactions 260\u003c\/p\u003e \u003cp\u003e11.2.1.6 Generation of Nickelalactone Without CO\u003csub\u003e2\u003c\/sub\u003e 261\u003c\/p\u003e \u003cp\u003e11.2.2 Reactivity of Nickelalactone 261\u003c\/p\u003e \u003cp\u003e11.2.2.1 Transmetalation with Organometallic Reagent 261\u003c\/p\u003e \u003cp\u003e11.2.2.2 β-Hydride Elimination 263\u003c\/p\u003e \u003cp\u003e11.2.2.3 Insertion of Another Unsaturated Molecule 264\u003c\/p\u003e \u003cp\u003e11.2.2.4 Retro-cyclization 265\u003c\/p\u003e \u003cp\u003e11.2.2.5 Nucleophilic Attack 265\u003c\/p\u003e \u003cp\u003e11.2.2.6 Oxidation 267\u003c\/p\u003e \u003cp\u003e11.2.2.7 Ligand Exchange 267\u003c\/p\u003e \u003cp\u003e11.3 Catalytic Transformation via Nickelalactone 1: Reactions of Alkynes 268\u003c\/p\u003e \u003cp\u003e11.3.1 Synthesis of Pyrone 268\u003c\/p\u003e \u003cp\u003e11.3.1.1 Initial Finding 268\u003c\/p\u003e \u003cp\u003e11.3.1.2 Reaction of Diynes with CO\u003csub\u003e2\u003c\/sub\u003e 268\u003c\/p\u003e \u003cp\u003e11.3.2 Synthesis of α,β-Unsaturated Ester 269\u003c\/p\u003e \u003cp\u003e11.3.2.1 Electrochemical Reactions 269\u003c\/p\u003e \u003cp\u003e11.3.2.2 Reduction with Organometallic Reagents 270\u003c\/p\u003e \u003cp\u003e11.4 Catalytic Transformation via Nickelalactone 2: Reactions of Alkenes and Related Molecules 271\u003c\/p\u003e \u003cp\u003e11.4.1 Transformation of Diene, Allene, and Substituted Alkene 271\u003c\/p\u003e \u003cp\u003e11.4.1.1 Coupling of Diene with CO\u003csub\u003e2\u003c\/sub\u003e 271\u003c\/p\u003e \u003cp\u003e11.4.1.2 Electrochemical Process 272\u003c\/p\u003e \u003cp\u003e11.4.1.3 Use of Reductant 272\u003c\/p\u003e \u003cp\u003e11.4.2 Synthesis of Acrylic Acid from Ethylene and CO\u003csub\u003e2 \u003c\/sub\u003e274\u003c\/p\u003e \u003cp\u003e11.4.2.1 Before the Dawn 275\u003c\/p\u003e \u003cp\u003e11.4.2.2 Development of Catalytic Reaction 276\u003c\/p\u003e \u003cp\u003e11.5 Concluding Remarks 278\u003c\/p\u003e \u003cp\u003eReferences 279\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Relevance of Ni(I) in Catalytic Carboxylation Reactions \u003c\/b\u003e\u003cb\u003e285\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRosie J. Somerville and Ruben Martin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 285\u003c\/p\u003e \u003cp\u003e12.2 Mechanistic Building Blocks 287\u003c\/p\u003e \u003cp\u003e12.2.1 Additives 287\u003c\/p\u003e \u003cp\u003e12.2.2 Coordination of CO\u003csub\u003e2\u003c\/sub\u003e 287\u003c\/p\u003e \u003cp\u003e12.2.3 Insertion\/C—C Bond Formation 288\u003c\/p\u003e \u003cp\u003e12.2.4 Ligand Effects 289\u003c\/p\u003e \u003cp\u003e12.2.5 Oxidative Addition 290\u003c\/p\u003e \u003cp\u003e12.2.6 Oxidation State 290\u003c\/p\u003e \u003cp\u003e12.2.7 Single Electron Transfer (SET) 290\u003c\/p\u003e \u003cp\u003e12.2.8 Conclusion 290\u003c\/p\u003e \u003cp\u003e12.3 Electrocarboxylation 291\u003c\/p\u003e \u003cp\u003e12.3.1 Introduction 291\u003c\/p\u003e \u003cp\u003e12.3.2 Phosphine Ligands 294\u003c\/p\u003e \u003cp\u003e12.3.3 Bipyridine and Related α-Diimine Ligands 296\u003c\/p\u003e \u003cp\u003e12.3.4 Salen Ligands 297\u003c\/p\u003e \u003cp\u003e12.3.5 Conclusion 298\u003c\/p\u003e \u003cp\u003e12.4 Non-electrochemical Methods 298\u003c\/p\u003e \u003cp\u003e12.4.1 Aryl Halides 300\u003c\/p\u003e \u003cp\u003e12.4.2 Benzyl Electrophiles 304\u003c\/p\u003e \u003cp\u003e12.4.3 Carboxylation of Unactivated Alkyl Electrophiles 306\u003c\/p\u003e \u003cp\u003e12.4.4 Carboxylation of Allyl Electrophiles 312\u003c\/p\u003e \u003cp\u003e12.4.5 Unsaturated Systems 315\u003c\/p\u003e \u003cp\u003e12.5 Conclusions 318\u003c\/p\u003e \u003cp\u003eReferences 319\u003c\/p\u003e \u003cp\u003eIndex 331\u003c\/p\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":48743120535895,"sku":"9783527344079","price":116.8,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783527344079.jpg?v=1720064199"},{"product_id":"organic-reaction-mechanisms-40-solved-cases-9783540003526","title":"Organic Reaction Mechanisms: 40 Solved Cases","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cstrong\u003e \u003c\/strong\u003e\u003cp\u003e\u003cstrong\u003eOrganic Reaction Mechanisms\u003c\/strong\u003e shows readers how to interpret the experimental data obtained from an organic reaction, and specifically how an organic reaction mechanism can be considered or rejected based on the analysis of the experimental evidence. Whilst examining a series of selected examples of mechanisms, the text focuses on real cases and discusses them in detail. The examples are arranged to elucidate key aspects of organic reaction mechanisms. The authors employ all the types of information that the authors of the original work considered useful and necessary, including spectroscopic data, kinetic and thermodynamic data, isotopic labelling and organic reactivity. The book makes an excellent primer for advanced undergraduates in chemistry who are preparing for exams and is also useful for graduate students and instructors.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eFrom the reviews:\u003c\/p\u003e \u003cp\u003e\"The authors of this book utilise recently published research work to illustrate and instruct the reader on how to interpret experimental data to account for product stereochemical outcomes and propose reasonable reaction mechanisms. Matching mechanisms to justify experimental results with no or limited supportive experimental evidence is tricky as often more questions are raised than answered, but in the majority of the 40 papers presented, Gallego and Sierra are reasonably convincing with their discussion of plausible mechanisms….. This book is suitable for the hyper-enthusiastic advanced organic chemistry undergraduates who are destined to higher research degree studies and for graduates and professional organic chemists who like linking experimental data to organic structures.\"\u003cbr\u003eChemistry in Australia, 10\/2004, p. 30\u003c\/p\u003e \u003cp\u003e\"The book makes an excellent primer for advanced undergraduates in chemistry who are preparing for exams and is also useful for graduates students and instructors.\"\u003cbr\u003eJournal: Chimie Nouvelle – Societe Royale de Chimie, Vol. 22, Issue 87, p. 122\u003c\/p\u003e \u003cp\u003e\"Organic Reaction Mechanisms shows readers how to interpret the experimental data obtained from an organic reaction … . Examining a series of selected examples of mechanisms, Organic Reaction Mechanisms focuses on real cases and discusses them in detail … . The book makes an excellent primer for advanced undergraduates in chemistry who are preparing for exams and is also useful for graduate students and instructors.\" (Chimie Nouvelle Societe Royale de Chemie, Vol. 22(87), 2004)\u003c\/p\u003e \u003cp\u003e\"Learning by doing is the approach pursued by Gallego and Sierra in their book … . The chemical concepts and reaction types introduced to the reader cover practically all of the addition, substitution, and elimination reactions known in traditional organic chemistry. … Ample space is also given to … . The book is a valuable resource for the preparation of seminars on organic reaction mechanisms, and as such it should be available in a good university library.\" (Hendrik Zipse, Angewandte Chemie, Vol. 116(37), 2004)\u003c\/p\u003e \u003cp\u003e\"Organic Reaction Mechanisms: 40 Solved Cases presents cases of organic reaction mechanisms using formal representation … . The examples are treated in detail with an introduction, experimental data, discussion, key points and additional references. The approach of the authors is original since they do not approach the reaction … . This volume will be useful to advanced undergraduate students and researchers interested in understanding the mechanism of organic reactions.\" (John F. Kennedy, Francois Meullenet, Carbohydrate Polymers, Vol. 57, 2004)\u003c\/p\u003e \u003cp\u003e\"Working with three-dimensional molecules, changes to solvent or catalyst and other such factors may dramatically alter the course of a reaction, and these subtleties are not readily appreciated by most students. … The authors of this book try to redress this deficiency by bringing together a series of organic reactions whose mechanistic details have been probed using a variety of techniques and approaches. … will also offer lecturers a useful set of worked problems with which to illustrate their courses.\" (Andrew Boa, Times Higher Education Supplement, February, 2005)\u003c\/p\u003e \u003cp\u003e\"Organic Reaction Mechanics shows the readers how to interpret the experimental data obtained from an organic reaction … . This book in which the strategy of synthesis has been discussed will be useful for undergraduates, Ph. D. students and scientists … . Lecturers can find in the text new examples to illustrate topics of advanced chemistry. After reading this book specific interest can be found by a physicist who deals with investigations of chemical or biochemical processes by physical methods.\" (Yu. Galyametdinov, Applied Magnetic Resonance, Vol. 28 (1-2), 2005)\u003c\/p\u003e \u003cp\u003e\"What resources do you need to teach mechanistic organic chemistry? More often than not, quick access to appropriate, contemporary examples … . For that reason alone I can commend Gomez Gallego and Sierra’s book … . The book is well organized. … The scope of the examples is a real asset. … The references are also valuable. … I can see it becoming a very useful resource for educators at advanced undergraduate and postgraduate level.\" (Jim Iley, Chemistry World, Vol. 2 (7), 2005)\u003c\/p\u003e \u003cp\u003e\"The mechanism of a chemical reaction can be considered as a hypothetical motion picture of the behavior of the participating atoms. The reliability of the proposed mechanism increases if it leads to quantitative predictions as to how the speed of the reaction is affected by concentrations of reactants, temperature, solvent and the presence of catalysts. The interpretation of the experimental data is a key point in any type of experimentation. The book on \u003cem\u003eOrganic Reaction\u003c\/em\u003e \u003cem\u003eMechanisms\u003c\/em\u003e explains the various approaches to interpret the experimental data obtained from an organic reaction and specifically how an organic reaction mechanism can be considered or rejected based on the analysis of experimental evidence. ...All the cases presented in the book have been nicely illustrated that cover all the main topics of organic chemistry and this book is an innovative contribution to the subject. In conclusion, this book can be excellent source of information not only to the students but also to the academicians working in the area of organic chemistry.\" (John F. Kennedy, Univ. Birmingham; Journal: Carbohydrate Polymers, Issue 65, 2006)  \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eLevel 1.- Case 1. A Surprise in the Synthesis of Guanacastepene A.- Case 2. Sulfenylation of Indole.- Case 3. Substrate Selective Reactions in the Presence of Lewis Acids.- Case 4. Diastereoselective Reductions of ?-Ketoesters.- Case 5. Rearrangements from Tetrahydropyran Derivatives.- Case 6. Stereospecific Substitution Reactions of Epoxy Sulfides.- Case 7. NaBH4 Reduction of ?,?-Unsaturated Chromium Carbene Complexes.- Case 8. Addition of Hydroxylamines to ?,?-Unsaturated Esters.- Case 9. Solvolysis of Electron-Deficient Norbornyl Triflates.- Case 10 Nucleophile Versus Base Catalysis.- Case 11. The Hydrolysis of p-Substituted Styrene Oxides.- Case 12. Elimination Reactions of Benzaldehyde O-Benzoyloximes.- Case 13. Oxygen Versus Sulfur Stabilization of Carbenium Ions.- Case 14. Cyclization of 2,3-Dibenzylidenesuccinates.- Case 15. Oxazoline N-Oxides as Dipoles in [3+2] Cycloadditions.- Case 16. Light-Induced Cycloadditions of N-Phthaloyl ?Amino Acids.- Level 2.- Case 17. Change in Rate-Determining Step in an E1 cB Mechanism: Aminolysis of Sulfamate Esters.- Case 18. Unusual Diels-Alder Reactivity of Acyclic 2-Azadienes.- Case 19. Chelate-Controlled Carbonyl Addition Reactions.- Case 20. Esterification of Carboxylic Acids with Dimethyl Carbonate and DBU.- Case 21. A Hammett Analysis in a Multistep Reaction: Rhodium(II)-Catalyzed Decomposition of ?Diazo Esters.- Case 22. Tandem Cycloadditions with Nitronates.- Case 23. Hydrolysis of 2-Aminobenzoate Esters.- Case 24. Rearrangements of Cyclobutenones.- Case 25. Epoxi Ester-Orthoester Rearrangement.- Case 26. 2-Chloro-1,3,5-triazines as Activating Groups of Carboxylic Acids in the Formation of Peptide Bonds.- Case 27. Acid-Catalyzed Isomerization of Imines.- Case 28. A Dearomatizing Disrotatory Electrocyclic Ring Closure.- Case 29. Stereoselective Debromination of Vicinal Dibromides.- Case 30. Diels-Alder Reactions of N-Acyl-1,2,4,5-tetrazines.- Case 31. Stereoselective Synthesis of 2-Acylaziridines.- Level 2.- Case 32. The Baylis-Hillman Reaction.- Case 33. The Rate-Determining Step in the SNAr Reaction.- Case 34. Helicenophanes and their Racemization.- Case 35. Solvolysis of Vinyl Iodonium Salts.- Case 36. Vicarious Nucleophilic Substitution.- Case 37. Base-promoted HF Elimination from 4-Fluoro-4-(4'-nitrophenyl)butan-2-one.- Case 38. Substitution of ?Halostyrenes Mes.- Case 39. Periodinane-Mediated Cyclization of Anilides.- Case 40. Solvolysis of 8-Deltacyclyl Brosylates.","brand":"Springer-Verlag Berlin and Heidelberg GmbH \u0026 Co. KG","offers":[{"title":"Default Title","offer_id":48743129514327,"sku":"9783540003526","price":66.49,"currency_code":"GBP","in_stock":true}]},{"product_id":"crystal-engineering-a-textbook-9789814338752","title":"Crystal Engineering: A Textbook","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book is important because it is the first textbook in an area that has become very popular in recent times. There are around 250 research groups in crystal engineering worldwide today. The subject has been researched for around 40 years but there is still no textbook at the level of senior undergraduates and beginning PhD students. This book is expected to fill this gap.The writing style is simple, with an adequate number of exercises and problems, and the diagrams are easy to understand. This book consists major areas of the subject, including organic crystals and co-ordination polymers, and can easily form the basis of a 30 to 40 lecture course for senior undergraduates.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction; Intermolecular Interactions; Design Strategies; Crystallisation; Polymorphism; Solvates and Co-Crystals; Co-Ordination Polymers.","brand":"World Scientific Publishing Co Pte Ltd","offers":[{"title":"Default Title","offer_id":48743298793815,"sku":"9789814338752","price":73.8,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9789814338752.jpg?v=1720064985"},{"product_id":"chemistryd3-9780198829980","title":"ChemistryD3","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eChemistry is widely considered to be the central science: it encompasses concepts on which all other branches of science are developed. Yet, for many students entering university, gaining a firm grounding in chemistry is a real challenge. Chemistry responds to this challenge, providing students with a full understanding of the fundamental principles of chemistry on which to build later studies.Uniquely amongst the introductory chemistry texts currently available, Chemistry''s author team brings together experts in each of organic, inorganic, and physical chemistry with specialists in chemistry education to provide balanced coverage of the fundamentals of chemistry in a way that students both enjoy and understand. The result is a text that builds on what students know already from school and tackles their misunderstandings and misconceptions, thereby providing a seamless transition from school to undergraduate study. Written with unrivalled clarity, students are encouraged to engage with the text and appreciate the central role that chemistry plays in our lives through the unique use of real-world context and photographs. Chemistry tackles head-on two issues pervading chemistry education: students'' mathematical skills, and their ability to see the subject as a single, unified discipline. Instead of avoiding the maths, Chemistry provides structured support, in the form of careful explanations, reminders of key mathematical concepts, step-by-step calculations in worked examples, and a Maths Toolkit, to help students get to grips with the essential mathematical element of chemistry. Frequent cross-references highlight the connections between each strand of chemistry and explain the relationship between the topics, so students can develop an understanding of the subject as a whole. Digital formats and resourcesChemistry is available for students and institutions to purchase in a variety of formats, and is supported by online resources. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk\/ebooks The e-book also features interactive animations of molecular structures, screencasts in which authors talk step-by-step through selected examples and key reaction mechanisms, and self-assessment activities for each chapter. The accompanying online resources will also include, for students:  Chapter 1 as an open-access PDF; Chapter summaries and key equations to download, to support revision; Worked solutions to the questions in the book.The following online resources are also provided for lecturers: Test bank of ready-made assessments for each chapter with which to test your students Problem-solving workshop activities for each chapter for you to use in class Case-studies showing how instructors are successfully using Chemistry3 in digital learning environments and to support innovative teaching practices Figures and tables from the book\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition It is a great textbook for first year courses with really good use of visual aids and excellent provision of worked examples to illustrate the concepts and their applications. It is a perfect transition from A-Level to Higher Education Chemistry. * Dr Rossana Wright, University of Nottingham *\u003cbr\u003eChemistry3 is the best introductory chemistry textbook currently available. It is well written, excels in clarity of presentation, and is an outstanding book from the student learning perspective. All of the concepts covered are well explained and supported by excellent artwork. This is a book that all first and second year chemistry undergraduates should have. * Dr Gareth Owen, University of South Wales *\u003cbr\u003eThis is an exemplar modern chemistry resource with a very rounded pedagogical approach to engaging students and supporting staff in delivering key chemical concepts and supporting facts. It is a one stop shop for mainstream chemistry fundamentals. * Dr Loretta M. Murphy, Bangor University *\u003cbr\u003eA fantastic all-round reference for university-level chemistry. It is a perfect way to bridge between school and university. * Adam Stubbs, student at Newcastle University *\u003cbr\u003eChemistry3 is the best university chemistry text book for first and second year science students. It is comprehensive and contains all the fundamentals for chemists to know- from analytical to organic chemistry. It is also a student friendly book with tons of pictures and applications of chemistry in the real world. * Christian Nichol J. Geronimo, student at Dublin Institute of Technology *\u003cbr\u003eThis material is fantastic and should be used alongside courses. The level of detail is exactly right for undergraduate courses and the colour coding of the boxes for worked examples and summaries make them really easy to find. There are lots of questions for you to have a go at which makes it easy to practice the new skills the book is helping to teach. * Rebecca Snelgrove, student at Keele University *\u003cbr\u003ePlenty of facts and figures are scattered throughout the text which makes reading not solely an educational, but also a fun activity. The examples of real life chemistry applications maintain the connection between theory and practice. The interdisciplinary approach provides a broader chemical understanding while not losing the comprehensiveness of the book. In short, a good all-in-one textbook for first-year students in chemistry. * Jelte van der Valk, student at the University of Groningen, the Netherlands *\u003cbr\u003eThe topics are very thoroughly explained and are at exactly the right level for the student. There are many great examples illustrating the topics. It is a great book to read and study from as a student starting university. This is definitely a book I would buy, read and return to, when I needed an explanation for some basic chemistry. * Michelle Rasmussen, student at the University of Roskilde, Denmark *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Fundamentals2. The language of organic chemistry3. Atomic structure and properties4. Diatomic molecules5. Polyatomic molecules6. Solids7. Acids and bases 8. Gases9. Reaction kinetics10. Molecular spectroscopy11. Analytical chemistry12. Molecular characterization13. Energy and thermochemistry14. Entropy and Gibbs energy15. Chemical equilibrium16. Electrochemistry17. Phase equilibrium and solutions18. Isomerism and stereochemistry19. Organic reaction mechanisms20. Halogenoalkanes21. Alkenes and alkynes22. Benzene and other aromatic compounds23. Aldehydes and ketones24. Carboxylic acids and derivatives25. Hydrogen26. s-Block chemistry27. p-Block chemistry28. d-Block chemistry","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48864217923927,"sku":"9780198829980","price":65.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198829980.jpg?v=1722270943"},{"product_id":"advanced-organic-chemistry-9780387683461","title":"Advanced Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e1: Chemical Bonding and Molecular Structure.- 2: Stereochemistry, Conformation, and Stereoselectivity.- 3: Structural Effects on Stability and Reactivity.- 4: Nucleophilic Substitution.- 5: Polar Addition and Elimination Reactions.- 6: Carbanions and Other Carbon Nucleophiles.- 7: Addition, Condensation and Substitution Reactions of Carbonyl Compounds.- 8: Aromaticity.- Aromatic Substitution.- 9: Concerted Pericyclic Reactions.- 10: Free Radical Reactions.- 11: Photochemistry.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eFrom the reviews of the fifth edition:\u003c\/p\u003e“Carey and Sundberg had written the most detailed and briliant account in the subject of organic chemistry. … The book provides an abundance of reaction examples organized in schemes. It makes studying very effective and helpful. … Advanced undergraduates and graduate students will welcome this new edition and the depth of materials covered.” (Philosophy, Religion and Science Book Reviews, bookinspections.wordpress.com, May, 2014)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eChemical Bonding and Molecular Structure.- Stereochemistry, Conformation, and Stereoselectivity.- Structural Effects on Stability and Reactivity.- Nucleophilic Substitution.- Polar Addition and Elimination Reactions.- Carbanions and Other Carbon Nucleophiles.- Addition, Condensation and Substitution Reactions of Carbonyl Compounds.- Aromaticity.- Aromatic Substitution.- Concerted Pericyclic Reactions.- Free Radical Reactions.- Photochemistry.","brand":"Springer-Verlag New York Inc.","offers":[{"title":"Default Title","offer_id":48864540295511,"sku":"9780387683461","price":71.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780387683461.jpg?v=1722272387"},{"product_id":"introduction-to-soft-matter-9780470516102","title":"Introduction to Soft Matter","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book provides an introduction to this exciting and relatively new subject with chapters covering natural and synthetic polymers, colloids, surfactants and liquid crystals highlighting the many and varied applications of these materials. Written by an expert in the field, this book will be an essential reference for people working in both industry and academia and will aid in understanding of this increasingly popular topic.  \u003cul\u003e \u003cli\u003e \u003cdiv\u003eContains a new chapter on biological soft matter\u003c\/div\u003e \u003c\/li\u003e \u003cli\u003e \u003cdiv\u003eNewly edited and updated chapters including updated coverage of recent aspects of polymer science.\u003c\/div\u003e \u003c\/li\u003e \u003cli\u003e \u003cdiv\u003eContain problems at the end of each chapter to facilitate understanding\u003c\/div\u003e \u003c\/li\u003e \u003c\/ul\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"...Introduction to Soft Matter is an extremely valuable textbook for undergraduate classes, and represents an excellent introductory reading for the researchers who venture on this field.\" (\u003ci\u003eMacromol. Chem. Phys\u003c\/i\u003e. 2008, 209, 1073)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface to the revised Edition.  \u003cp\u003ePreface to the First Edition.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1. Introduction.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.2 Intermolecular Interactions.\u003c\/p\u003e \u003cp\u003e1.3 Structural Organization.\u003c\/p\u003e \u003cp\u003e1.4 Dynamics.\u003c\/p\u003e \u003cp\u003e1.5 Phase Transitions.\u003c\/p\u003e \u003cp\u003e1.6 Order Parameters.\u003c\/p\u003e \u003cp\u003e1.7 Scaling Laws.\u003c\/p\u003e \u003cp\u003e1.8 Polydispersity.\u003c\/p\u003e \u003cp\u003e1.9 Experimental Techniques for Investigating Soft Matter.\u003c\/p\u003e \u003cp\u003e1.10 Computer Simulation.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2. Polymers.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.2 Synthesis.\u003c\/p\u003e \u003cp\u003e2.3 Polymer Chain Conformation.\u003c\/p\u003e \u003cp\u003e2.4 Characterization.\u003c\/p\u003e \u003cp\u003e2.5 Polymer Solutions.\u003c\/p\u003e \u003cp\u003e2.6 Amorphous Polymers.\u003c\/p\u003e \u003cp\u003e2.7 Crystalline Polymers.\u003c\/p\u003e \u003cp\u003e2.8 Plastics.\u003c\/p\u003e \u003cp\u003e2.9 Rubber.\u003c\/p\u003e \u003cp\u003e2.10 Fibres.\u003c\/p\u003e \u003cp\u003e2.11 Polymer Blends and Block Copolymers.\u003c\/p\u003e \u003cp\u003e2.12 Dendrimers and Hyperbranched Polymers.\u003c\/p\u003e \u003cp\u003e2.13 Polyelectrolytes.\u003c\/p\u003e \u003cp\u003e2.14 Electronic and Opto-electronic Polymers.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003eQuestions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3. Colloids.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 Types of Colloids.\u003c\/p\u003e \u003cp\u003e3.3 Forces Between Colloidal Particles.\u003c\/p\u003e \u003cp\u003e3.4 Characterization of Colloids.\u003c\/p\u003e \u003cp\u003e3.5 Charge Stabilization.\u003c\/p\u003e \u003cp\u003e3.6 Steric Stabilization.\u003c\/p\u003e \u003cp\u003e3.7 Effect of Polymers on Colloid Stability.\u003c\/p\u003e \u003cp\u003e3.8 Kinetic Properties.\u003c\/p\u003e \u003cp\u003e3.9 Sols.\u003c\/p\u003e \u003cp\u003e3.10 Gels.\u003c\/p\u003e \u003cp\u003e3.11 Clays.\u003c\/p\u003e \u003cp\u003e3.12 Foams.\u003c\/p\u003e \u003cp\u003e3.13 Emulsions.\u003c\/p\u003e \u003cp\u003e3.14 Food Colloids.\u003c\/p\u003e \u003cp\u003e3.15 Concentrated Colloidal Dispersions.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003eQuestions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4. Amphiphiles.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 Types of Amphiphile.\u003c\/p\u003e \u003cp\u003e4.3 Surface Activity.\u003c\/p\u003e \u003cp\u003e4.4 Surfactant Monolayers and Langmuir-Blodgett Films.\u003c\/p\u003e \u003cp\u003e4.5 Adsorption at Solid Interfaces.\u003c\/p\u003e \u003cp\u003e4.6 Micellization and the Critical Micelle Concentration.\u003c\/p\u003e \u003cp\u003e4.7 Detergency.\u003c\/p\u003e \u003cp\u003e4.8 Solubilization in Micelles.\u003c\/p\u003e \u003cp\u003e4.9 Interfacial Curvature and Its Relationship to Molecular Structure.\u003c\/p\u003e \u003cp\u003e4.10 Liquid Crystal Phases at High Concentrations.\u003c\/p\u003e \u003cp\u003e4.11 Membranes.\u003c\/p\u003e \u003cp\u003e4.12 Templated Structures.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003eQuestions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5. Liquid Crystals.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Types of Liquid Crystals.\u003c\/p\u003e \u003cp\u003e5.3 Characteristics of Liquid Crystal Phases.\u003c\/p\u003e \u003cp\u003e5.4 Identification of Liquid Crystal Phases.\u003c\/p\u003e \u003cp\u003e5.5 Orientational Order.\u003c\/p\u003e \u003cp\u003e5.6 Elastic Properties.\u003c\/p\u003e \u003cp\u003e5.7 Phase Transitions in Liquid Crystals.\u003c\/p\u003e \u003cp\u003e5.8 Applications of Liquid Crystals.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003eQuestions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6. Biological Soft Matter.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Lipid Membranes.\u003c\/p\u003e \u003cp\u003e6.3 DNA.\u003c\/p\u003e \u003cp\u003e6.4 Proteins.\u003c\/p\u003e \u003cp\u003e6.5 Polysaccharides and Glycoproteins.\u003c\/p\u003e \u003cp\u003e6.6 Macromolecular Assemblies.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003eQuestions.\u003c\/p\u003e \u003cp\u003eNumerical Solutions to Questions.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48864630636887,"sku":"9780470516102","price":43.65,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470516102.jpg?v=1722272813"},{"product_id":"kiemle-d-spectrometric-identification-of-organic-compounds-9780470616376","title":"Kiemle D Spectrometric Identification of Organic","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eFirst published over 40 years ago, this was the first text on the identification of organic compounds using spectroscopy. This text presents a unified approach to the structure determination of organic compounds based largely on mass spectrometry, infrared (IR) spectroscopy, as well as multinuclear and multidimensional nuclear magnetic resonance (NMR) spectroscopy. The key strength of this text is the extensive set of practice and real-data problems (in Chapters 7 and 8). Even professional chemists use these spectra as reference data. \u003ci\u003eSpectrometric Identification of Organic Compounds\u003c\/i\u003e is written by and for organic chemists, and emphasizes the synergistic effect resulting from the interplay of spectra. This text is characterized by its problem-solving approach with numerous practice problems and extensive reference charts and tables.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eCHAPTER 1 MASS SPECTROMETRY 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e1.2 Instrumentation 2\u003c\/p\u003e \u003cp\u003e1.3 Ionization Methods 3\u003c\/p\u003e \u003cp\u003e1.4 Mass Analyzers 8\u003c\/p\u003e \u003cp\u003e1.5 Interpretation of EI Mass Spectra 12\u003c\/p\u003e \u003cp\u003e1.6 Mass Spectra of Some Chemical Classes 18\u003c\/p\u003e \u003cp\u003eReferences 37\u003c\/p\u003e \u003cp\u003eStudent Exercises 37\u003c\/p\u003e \u003cp\u003eAppendices 46\u003c\/p\u003e \u003cp\u003eA Formula Masses (FM) for Various Combinations of Carbon, Hydrogen, Nitrogen, and Oxygen 46\u003c\/p\u003e \u003cp\u003eB Common Fragment Ions 67\u003c\/p\u003e \u003cp\u003eC Common Fragments Lost 69\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 2 INFRARED SPECTROSCOPY 71\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 71\u003c\/p\u003e \u003cp\u003e2.2 Theory 71\u003c\/p\u003e \u003cp\u003e2.3 Instrumentation 76\u003c\/p\u003e \u003cp\u003e2.4 Sample Handling 77\u003c\/p\u003e \u003cp\u003e2.5 Interpretation of Spectra 78\u003c\/p\u003e \u003cp\u003e2.6 Characteristic Group Absorptions of Organic Molecules 81\u003c\/p\u003e \u003cp\u003eReferences 108\u003c\/p\u003e \u003cp\u003eStudent Exercises 108\u003c\/p\u003e \u003cp\u003eAppendices 118\u003c\/p\u003e \u003cp\u003eA Transparent Regions of Solvents and Mulling Oils 118\u003c\/p\u003e \u003cp\u003eB Characteristic Group Absorptions 119\u003c\/p\u003e \u003cp\u003eC Absorptions for Alkenes 124\u003c\/p\u003e \u003cp\u003eD Absorptions for Phosphorus Compounds 125\u003c\/p\u003e \u003cp\u003eE Absorptions for Heteroaromatics 125\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 3 PROTON (1H) MAGNETIC RESONANCE SPECTROSCOPY 126\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 126\u003c\/p\u003e \u003cp\u003e3.2 Theory 126\u003c\/p\u003e \u003cp\u003e3.3 Instrumentation and Sample Handling 129\u003c\/p\u003e \u003cp\u003e3.4 Chemical Shift 132\u003c\/p\u003e \u003cp\u003e3.5 Spin-Spin Coupling, Multiplets, and Spin Systems 137\u003c\/p\u003e \u003cp\u003e3.6 Protons on Oxygen, Nitrogen, and Sulfur Atoms:Exchangeable Protons 144\u003c\/p\u003e \u003cp\u003e3.7 Coupling of Protons to Other Important Nuclei (19F, D (2H), 31P, 29Si, and 13C) 149\u003c\/p\u003e \u003cp\u003e3.8 Chemical Equivalence 150\u003c\/p\u003e \u003cp\u003e3.9 Magnetic Equivalence 154\u003c\/p\u003e \u003cp\u003e3.10 AMX, ABX, and ABC Rigid Systems with Three Coupling Constants 155\u003c\/p\u003e \u003cp\u003e3.11 Weakly and Strongly Coupled Systems: Virtual Coupling 156\u003c\/p\u003e \u003cp\u003e3.12 Chirality 158\u003c\/p\u003e \u003cp\u003e3.13 Magnitude of Vicinal and Geminal Coupling Constants 160\u003c\/p\u003e \u003cp\u003e3.14 Long-Range Coupling 162\u003c\/p\u003e \u003cp\u003e3.15 Selective Spin Decoupling: Double Resonance 162\u003c\/p\u003e \u003cp\u003e3.16 Nuclear Overhauser Effect 162\u003c\/p\u003e \u003cp\u003e3.17 Conclusion 163\u003c\/p\u003e \u003cp\u003eReferences 164\u003c\/p\u003e \u003cp\u003eStudent Exercises 164\u003c\/p\u003e \u003cp\u003eAppendices 175\u003c\/p\u003e \u003cp\u003eA Chart A.1: Chemical Shifts of Protons on a Carbon Atom Adjacent (𝛼 Position) to a Functional Group in Aliphatic Compounds (M–Y) 175\u003c\/p\u003e \u003cp\u003eChart A.2: Chemical Shifts of Protons on a Carbon Atom Once Removed (𝛽 Position) from a Functional Group in Aliphatic Compounds (M–C–Y) 177\u003c\/p\u003e \u003cp\u003eB Effect on Chemical Shifts by Two or Three Directly Attached Functional Groups 178\u003c\/p\u003e \u003cp\u003eC Chemical Shifts in Alicyclic and Heterocyclic Rings 180\u003c\/p\u003e \u003cp\u003eD Chemical Shifts in Unsaturated and Aromatic Systems 181\u003c\/p\u003e \u003cp\u003eChart D.1: Chemical Shifts of Protons on Monosubstituted Benzene Rings 183\u003c\/p\u003e \u003cp\u003eE Protons Subject to Hydrogen-Bonding Effects (Protons on Heteroatoms) 184\u003c\/p\u003e \u003cp\u003eF Proton Spin-Spin Coupling Constants 185\u003c\/p\u003e \u003cp\u003eG Chemical Shifts and Multiplicities of Residual Protons in Commercially Available Deuterated Solvents 187\u003c\/p\u003e \u003cp\u003eH Chemical Shifts of Common Laboratory Solvents as Trace Impurities 188\u003c\/p\u003e \u003cp\u003eI Proton NMR Chemical Shifts of Amino Acids in D2O 190\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 4 CARBON-13 NMR SPECTROSCOPY 191\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 191\u003c\/p\u003e \u003cp\u003e4.2 Theory 191\u003c\/p\u003e \u003cp\u003e4.3 Interpretation of a Simple 13C NMR Spectrum: Diethyl Phthalate 198\u003c\/p\u003e \u003cp\u003e4.4 Quantitative 13C Analysis 198\u003c\/p\u003e \u003cp\u003e4.5 Chemical Equivalence 200\u003c\/p\u003e \u003cp\u003e4.6 DEPT 200\u003c\/p\u003e \u003cp\u003e4.7 Chemical Classes and Chemical Shifts 203\u003c\/p\u003e \u003cp\u003e4.7.1 Alkanes 204\u003c\/p\u003e \u003cp\u003e4.7.1.1 Linear and Branched Alkanes 204\u003c\/p\u003e \u003cp\u003e4.7.1.2 Effect of Substituents on Alkanes 205\u003c\/p\u003e \u003cp\u003e4.7.1.3 Cycloalkanes and Saturated Heterocyclics 205\u003c\/p\u003e \u003cp\u003e4.7.2 Alkenes 206\u003c\/p\u003e \u003cp\u003e4.7.3 Alkynes 208\u003c\/p\u003e \u003cp\u003e4.7.4 Aromatic Compounds 208\u003c\/p\u003e \u003cp\u003e4.7.5 Heteroaromatic Compounds 209\u003c\/p\u003e \u003cp\u003e4.7.6 Alcohols 209\u003c\/p\u003e \u003cp\u003e4.7.7 Ethers, Acetals, and Epoxides 209\u003c\/p\u003e \u003cp\u003e4.7.8 Halides 211\u003c\/p\u003e \u003cp\u003e4.7.9 Amines 211\u003c\/p\u003e \u003cp\u003e4.7.10 Thiols, Sulfides, and Disulfides 211\u003c\/p\u003e \u003cp\u003e4.7.11 Functional Groups Containing Carbon 211\u003c\/p\u003e \u003cp\u003e4.7.11.1 Ketones and Aldehydes 212\u003c\/p\u003e \u003cp\u003e4.7.11.2 Carboxylic Acids, Esters, Chlorides, Anhydrides, Amides, and Nitriles 214\u003c\/p\u003e \u003cp\u003e4.7.11.3 Oximes 214\u003c\/p\u003e \u003cp\u003eReferences 214\u003c\/p\u003e \u003cp\u003eStudent Exercises 214\u003c\/p\u003e \u003cp\u003eAppendices 225\u003c\/p\u003e \u003cp\u003eA The 13C Chemical Shifts, Coupling Constants, and Peak Multiplicities of Common Deuterated NMR Solvents 225\u003c\/p\u003e \u003cp\u003eB 13C Chemical Shifts of Common Laboratory Solvents as Trace Impurities in Selected Deuterated NMR Solvents 226\u003c\/p\u003e \u003cp\u003eC 13C Chemical Shift Ranges for Chemical Classes 227\u003c\/p\u003e \u003cp\u003eD 13C Chemical Shifts (ppm) for Several Natural Products 229\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 5 TWO-DIMENSIONAL NMR SPECTROSCOPY 230\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 230\u003c\/p\u003e \u003cp\u003e5.2 Theory 231\u003c\/p\u003e \u003cp\u003e5.3 Correlation Spectroscopy 233\u003c\/p\u003e \u003cp\u003e5.3.1 \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH Correlation: COSY 235\u003c\/p\u003e \u003cp\u003e5.4 Ipsenol: \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH COSY 235\u003c\/p\u003e \u003cp\u003e5.4.1 Ipsenol: Double Quantum Filtered \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e1\u003c\/sup\u003eH COSY 238\u003c\/p\u003e \u003cp\u003e5.4.2 Carbon Detected \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e1\u003c\/sup\u003eH COSY: HETCOR 238\u003c\/p\u003e \u003cp\u003e5.4.3 Proton Detected \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e13\u003c\/sup\u003eC COSY: HMQC 239\u003c\/p\u003e \u003cp\u003e5.4.4 Ipsenol: HETCOR and HMQC 239\u003c\/p\u003e \u003cp\u003e5.4.5 Ipsenol: Proton-Detected, Long-Range \u003csup\u003e1\u003c\/sup\u003eH-\u003csup\u003e13\u003c\/sup\u003eC Heteronuclear Correlation: HMBC 241\u003c\/p\u003e \u003cp\u003e5.5 Caryophyllene Oxide 243\u003c\/p\u003e \u003cp\u003e5.5.1 Caryophyllene Oxide: DQF-COSY 243\u003c\/p\u003e \u003cp\u003e5.5.2 Caryophyllene Oxide: HMQC 243\u003c\/p\u003e \u003cp\u003e5.5.3 Caryophyllene Oxide: HMBC 247\u003c\/p\u003e \u003cp\u003e5.6 \u003csup\u003e13\u003c\/sup\u003eC-\u003csup\u003e13\u003c\/sup\u003eC Correlations: INADEQUATE 249\u003c\/p\u003e \u003cp\u003e5.6.1 INADEQUATE: Caryophyllene Oxide 251\u003c\/p\u003e \u003cp\u003e5.7 Lactose 251\u003c\/p\u003e \u003cp\u003e5.7.1 DQF-COSY: Lactose 251\u003c\/p\u003e \u003cp\u003e5.7.2 HMQC: Lactose 254\u003c\/p\u003e \u003cp\u003e5.7.3 HMBC: Lactose 254\u003c\/p\u003e \u003cp\u003e5.8 Relayed Coherence Transfer: TOCSY 254\u003c\/p\u003e \u003cp\u003e5.8.1 2D TOCSY: Lactose 254\u003c\/p\u003e \u003cp\u003e5.8.2 1D TOCSY: Lactose 257\u003c\/p\u003e \u003cp\u003e5.9 HMQC-TOCSY 259\u003c\/p\u003e \u003cp\u003e5.9.1 HMQC-TOCSY: Lactose 259\u003c\/p\u003e \u003cp\u003e5.10 ROESY 259\u003c\/p\u003e \u003cp\u003e5.10.1 ROESY: Lactose 259\u003c\/p\u003e \u003cp\u003e5.11 VGSE 262\u003c\/p\u003e \u003cp\u003e5.11.1 COSY: VGSE 262\u003c\/p\u003e \u003cp\u003e5.11.2 TOCSY: VGSE 262\u003c\/p\u003e \u003cp\u003e5.11.3 HMQC: VGSE 262\u003c\/p\u003e \u003cp\u003e5.11.4 HMBC: VGSE 264\u003c\/p\u003e \u003cp\u003e5.11.5 ROESY: VGSE 265\u003c\/p\u003e \u003cp\u003e5.12 Pulsed Field Gradient NMR 265\u003c\/p\u003e \u003cp\u003eReferences 268\u003c\/p\u003e \u003cp\u003eStudent Exercises 268\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 6 MULTINUCLEAR MAGNETIC RESONANCE SPECTROSCOPY 298\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction and General Considerations 298\u003c\/p\u003e \u003cp\u003e6.2 15N Nuclear Magnetic Resonance 299\u003c\/p\u003e \u003cp\u003e6.3 19F Nuclear Magnetic Resonance 306\u003c\/p\u003e \u003cp\u003e6.4 29Si Nuclear Magnetic Resonance 309\u003c\/p\u003e \u003cp\u003e6.5 31P Nuclear Magnetic Resonance 312\u003c\/p\u003e \u003cp\u003e6.6 Conclusions 315\u003c\/p\u003e \u003cp\u003eReferences 315\u003c\/p\u003e \u003cp\u003eStudent Exercises 315\u003c\/p\u003e \u003cp\u003eAppendix 320\u003c\/p\u003e \u003cp\u003eA Properties of Magnetically Active Nuclei 320\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 7 SOLVED PROBLEMS 325\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 325\u003c\/p\u003e \u003cp\u003eProblem 7.1 Discussion 329\u003c\/p\u003e \u003cp\u003eProblem 7.2 Discussion 333\u003c\/p\u003e \u003cp\u003eProblem 7.3 Discussion 337\u003c\/p\u003e \u003cp\u003eProblem 7.4 Discussion 344\u003c\/p\u003e \u003cp\u003eProblem 7.5 Discussion 350\u003c\/p\u003e \u003cp\u003eProblem 7.6 Discussion 356\u003c\/p\u003e \u003cp\u003eStudent Exercises 357\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 8 ASSIGNED PROBLEMS 364\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 364\u003c\/p\u003e \u003cp\u003eINDEX 453\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48864634339671,"sku":"9780470616376","price":205.16,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470616376.jpg?v=1722272824"},{"product_id":"organic-synthesis-9780470712368","title":"Organic Synthesis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOne approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e?The authors have succeeded admirably in the updating of a classic in the pedagogy of organic chemistry.? ( \u003ci\u003eJournal of Medicinal Chemistry\u003c\/i\u003e , August 2009)  \u003cp\u003e?This book is suitable for advanced undergraduate students, researchers and professional chemists. Both the writing and the diagrams are simple and clear.? ( \u003ci\u003eReviews\u003c\/i\u003e, May 2009)\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eGeneral References xi\u003c\/p\u003e \u003cp\u003e1. The Disconnection Approach 1\u003c\/p\u003e \u003cp\u003e2. Basic Principles: Synthons and Reagents Synthesis of Aromatic Compounds 7\u003c\/p\u003e \u003cp\u003e3. Strategy I: The Order of Events 17\u003c\/p\u003e \u003cp\u003e4. One-Group C–X Disconnections 23\u003c\/p\u003e \u003cp\u003e5. Strategy II: Chemoselectivity 29\u003c\/p\u003e \u003cp\u003e6. Two-Group C–X Disconnections 35\u003c\/p\u003e \u003cp\u003e7. Strategy III: Reversal of Polarity, Cyclisations, Summary of Strategy 45\u003c\/p\u003e \u003cp\u003e8. Amine Synthesis 53\u003c\/p\u003e \u003cp\u003e9. Strategy IV: Protecting Groups 61\u003c\/p\u003e \u003cp\u003e10. One Group C–C Disconnections I: Alcohols 69\u003c\/p\u003e \u003cp\u003e11. General Strategy A: Choosing a Disconnection 77\u003c\/p\u003e \u003cp\u003e12. Strategy V: Stereoselectivity A 83\u003c\/p\u003e \u003cp\u003e13. One Group C–C Disconnections II: Carbonyl Compounds 93\u003c\/p\u003e \u003cp\u003e14. Strategy VI: Regioselectivity 101\u003c\/p\u003e \u003cp\u003e15. Alkene Synthesis 107\u003c\/p\u003e \u003cp\u003e16. Strategy VII: Use of Acetylenes (Alkynes) 115\u003c\/p\u003e \u003cp\u003e17. Two-Group C–C Disconnections I: Diels-Alder Reactions 121\u003c\/p\u003e \u003cp\u003e18. Strategy VIII: Introduction to Carbonyl Condensations 129\u003c\/p\u003e \u003cp\u003e19. Two-Group C–C Disconnections II: 1,3-Difunctionalised Compounds 133\u003c\/p\u003e \u003cp\u003e20. Strategy IX: Control in Carbonyl Condensations 139\u003c\/p\u003e \u003cp\u003e21. Two-Group C–C Disconnections III: 1,5-Difunctionalised Compounds Conjugate (Michael) Addition and Robinson Annelation 151\u003c\/p\u003e \u003cp\u003e22. Strategy X: Aliphatic Nitro Compounds in Synthesis 161\u003c\/p\u003e \u003cp\u003e23. Two-Group Disconnections IV: 1,2-Difunctionalised Compounds 167\u003c\/p\u003e \u003cp\u003e24. Strategy XI: Radical Reactions in Synthesis 177\u003c\/p\u003e \u003cp\u003e25. Two-Group Disconnections V: 1,4-Difunctionalised Compounds 185\u003c\/p\u003e \u003cp\u003e26. Strategy XII: Reconnection 193\u003c\/p\u003e \u003cp\u003e27. Two-Group C–C Disconnections VI: 1,6-diCarbonyl Compounds 199\u003c\/p\u003e \u003cp\u003e28. General Strategy B: Strategy of Carbonyl Disconnections 207\u003c\/p\u003e \u003cp\u003e29. Strategy XIII: Introduction to Ring Synthesis: Saturated Heterocycles 217\u003c\/p\u003e \u003cp\u003e30. Three-Membered Rings 229\u003c\/p\u003e \u003cp\u003e31. Strategy XIV: Rearrangements in Synthesis 237\u003c\/p\u003e \u003cp\u003e32. Four-Membered Rings: Photochemistry in Synthesis 245\u003c\/p\u003e \u003cp\u003e33. Strategy XV: The Use of Ketenes in Synthesis 251\u003c\/p\u003e \u003cp\u003e34. Five-Membered Rings 255\u003c\/p\u003e \u003cp\u003e35. Strategy XVI: Pericyclic Reactions in Synthesis: Special Methods for Five-Membered Rings 261\u003c\/p\u003e \u003cp\u003e36. Six-Membered Rings 269\u003c\/p\u003e \u003cp\u003e37. General Strategy C: Strategy of Ring Synthesis 279\u003c\/p\u003e \u003cp\u003e38. Strategy XVII: Stereoselectivity B 289\u003c\/p\u003e \u003cp\u003e39. Aromatic Heterocycles 301\u003c\/p\u003e \u003cp\u003e40. General Strategy D: Advanced Strategy 313\u003c\/p\u003e \u003cp\u003eIndex 325\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48864638337367,"sku":"9780470712368","price":34.15,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470712368.jpg?v=1722272841"},{"product_id":"workbook-for-organic-synthesis-9780471929642","title":"Workbook for Organic Synthesis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWorkbook for Organic Synthesis: Strategy and Control   Paul Wyatt  Senior Lecturer and Director of Undergraduate Studies, School of Chemistry, University of Bristol, UK   Stuart Warren  Reader in Organic Chemistry, Department of Chemistry, University of Cambridge, UK.      Workbook for Organic Synthesis: Strategy and Control This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: Strategy and Control. Each problem is followed by a fully explained solution and discussion. The examples extend the student's experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Together the workbook and textbook provide a complete course in advanced organic synthesis.      Organic Synthesis: Strategy and Control Organic Synthesis: Strategy and Control is a sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach. The 'Disconnection' book concentrated on the planning behind the synthesis of compounds. This book focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work.      The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. Interpenetrating this structure, the 36 chapters start with classic methods and progress to modern methods and modern strategic considerations. Heterocyclic chemistry is treated throughout the book with full mechanistic explanations as part of organic chemistry rather than a separate entity.      Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e?This is a must-read for any final year undergrad or PhD? student in organic chemistry, but it's more than that?it's a book for experienced chemists too.? (\u003ci\u003eReviews\u003c\/i\u003e, May 2009)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003e\u003cb\u003eA: Introduction: Selectivity 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Planning Organic Syntheses: Tactics, Strategy and Control 3\u003c\/p\u003e \u003cp\u003e2. Chemoselectivity 7\u003c\/p\u003e \u003cp\u003e3. Regioselectivity: Controlled Aldol Reactions 19\u003c\/p\u003e \u003cp\u003e4. Stereoselectivity: Stereoselective Aldol Reactions 35\u003c\/p\u003e \u003cp\u003e5. Alternative Strategies for Enone Synthesis 47\u003c\/p\u003e \u003cp\u003e6. Choosing a Strategy: The Synthesis of Cyclopentenones 57\u003c\/p\u003e \u003cp\u003e\u003cb\u003eB: Making Carbon–Carbon Bonds 69\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7. The Ortho Strategy for Aromatic Compounds 71\u003c\/p\u003e \u003cp\u003e8. σ-Complexes of Metals 91\u003c\/p\u003e \u003cp\u003e9. Controlling the Michael Reaction 103\u003c\/p\u003e \u003cp\u003e10. Specific Enol Equivalents 115\u003c\/p\u003e \u003cp\u003e11. Extended Enolates 123\u003c\/p\u003e \u003cp\u003e12. Allyl Anions 135\u003c\/p\u003e \u003cp\u003e13. Homoenolates 147\u003c\/p\u003e \u003cp\u003e14. Acyl Anion Equivalents 155\u003c\/p\u003e \u003cp\u003e\u003cb\u003eC: Carbon–Carbon Double Bonds 169\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15. Synthesis of Double Bonds of Defined Stereochemistry 171\u003c\/p\u003e \u003cp\u003e16. Vinyl Anions 191\u003c\/p\u003e \u003cp\u003e17. Electrophilic Attack on Alkenes 203\u003c\/p\u003e \u003cp\u003e18. Vinyl Cations 221\u003c\/p\u003e \u003cp\u003e19. Allyl Alcohols: Allyl Cation Equivalents (and More) 241\u003c\/p\u003e \u003cp\u003e\u003cb\u003eD: Stereochemistry 257\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20. Control of Stereochemistry–Introduction 259\u003c\/p\u003e \u003cp\u003e21. Diastereoselectivity 269\u003c\/p\u003e \u003cp\u003e22. Resolution 283\u003c\/p\u003e \u003cp\u003e23. The Chiral Pool: Asymmetric Synthesis with Natural Products as Starting Materials 295\u003c\/p\u003e \u003cp\u003e24. Asymmetric Induction I: Reagent-Based Strategy 309\u003c\/p\u003e \u003cp\u003e25. Asymmetric Induction II: Asymmetric Catalysis: Formation of C–O and C–N Bonds 321\u003c\/p\u003e \u003cp\u003e26. Asymmetric Induction III: Asymmetric Catalysis: Formation of C–H and C–C Bonds 335\u003c\/p\u003e \u003cp\u003e27. Asymmetric Induction IV: Substrate-Based Strategy 351\u003c\/p\u003e \u003cp\u003e28. Kinetic Resolution 365\u003c\/p\u003e \u003cp\u003e29. Enzymes: Biological Methods in Asymmetric Synthesis 377\u003c\/p\u003e \u003cp\u003e30. New Chiral Centres from Old: Enantiomerically Pure Compounds and Sophisticated Syntheses 391\u003c\/p\u003e \u003cp\u003e31. Strategy of Asymmetric Synthesis 405\u003c\/p\u003e \u003cp\u003e\u003cb\u003eE: Functional Group Strategy 417\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e32. Functionalisation of Pyridine 419\u003c\/p\u003e \u003cp\u003e33. Oxidation of Aromatic Rings and of Enol(ate)s 433\u003c\/p\u003e \u003cp\u003e34. Functionality and Pericyclic Reactions: Nitrogen Heterocycles by Cycloadditions and Sigmatropic Rearrangements 447\u003c\/p\u003e \u003cp\u003e35. Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms 459\u003c\/p\u003e \u003cp\u003e36. Tandem Organic Reactions 473\u003c\/p\u003e \u003cp\u003eIndex 483\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48864653345111,"sku":"9780471929642","price":45.55,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780471929642.jpg?v=1722272911"},{"product_id":"how-to-solve-organic-reaction-mechanisms-9781118401590","title":"How To Solve Organic Reaction Mechanisms","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eHow To Solve Organic Reaction Mechanisms: A Stepwise Approach is an upgraded and much-expanded sequel to the bestselling text Reaction Mechanisms at a Glance.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface vi\u003c\/p\u003e \u003cp\u003eAbbreviations vii\u003c\/p\u003e \u003cp\u003eAbout the companion website viii\u003c\/p\u003e \u003cp\u003eIntroduction ix\u003c\/p\u003e \u003cp\u003e1 Nucleophilic substitution and elimination 1\u003c\/p\u003e \u003cp\u003e2 Alkene and alkyne chemistry 32\u003c\/p\u003e \u003cp\u003e3 Nucleophilic additions to carbonyl groups 64\u003c\/p\u003e \u003cp\u003e4 Enolate chemistry 96\u003c\/p\u003e \u003cp\u003e5 Aromatic chemistry 128\u003c\/p\u003e \u003cp\u003e6 Rearrangements 160\u003c\/p\u003e \u003cp\u003e7 Ligand coupling processes 192\u003c\/p\u003e \u003cp\u003eIndex 224\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48866370224471,"sku":"9781118401590","price":35.1,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118401590.jpg?v=1722278326"},{"product_id":"organic-chemistry-i-for-dummies-9781119293378","title":"Organic Chemistry I For Dummies","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOrganic Chemistry I For Dummies, 2nd Edition (9781119293378) was previously published as Organic Chemistry I For Dummies, 2nd Edition (9781118828076). While this version features a new Dummies cover and design, the content is the same as the prior release and should not be considered a new or updated product.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eIntroduction 1\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 1: Getting Started with Organic Chemistry 5\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 1: The Wonderful World of Organic Chemistry 7\u003c\/p\u003e \u003cp\u003eChapter 2: Dissecting Atoms: Atomic Structure and Bonding 15\u003c\/p\u003e \u003cp\u003eChapter 3: Speaking with Pictures: Drawing Structures 35\u003c\/p\u003e \u003cp\u003eChapter 4: Covering the Bases (And the Acids) 57\u003c\/p\u003e \u003cp\u003eChapter 5: Reactivity Centers: Functional Groups 67\u003c\/p\u003e \u003cp\u003eChapter 6: Seeing in 3-D: Stereochemistry 81\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 2: Hydrocarbons 97\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 7: What’s in a Name? Alkane Nomenclature 99\u003c\/p\u003e \u003cp\u003eChapter 8: Drawing Alkanes 107\u003c\/p\u003e \u003cp\u003eChapter 9: Seeing Double: The Alkenes 123\u003c\/p\u003e \u003cp\u003eChapter 10: Reactions of Alkenes 137\u003c\/p\u003e \u003cp\u003eChapter 11: It Takes Alkynes: The Carbon-Carbon Triple Bond 149\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 3: Functional Groups 157\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 12: Replacing and Removing: Substitution and Elimination Reactions 159\u003c\/p\u003e \u003cp\u003eChapter 13: Getting Drunk on Organic Molecules: The Alcohols 175\u003c\/p\u003e \u003cp\u003eChapter 14: Side-by-Side: Conjugated Alkenes and the Diels–Alder Reaction 183\u003c\/p\u003e \u003cp\u003eChapter 15: Lord of the Rings: Aromatic Compounds 193\u003c\/p\u003e \u003cp\u003eChapter 16: Bringing Out the Howitzers: Reactions of Aromatic Compounds 209\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 4: Spectroscopy and Structure Determination 223\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 17: A Smashing Time: Mass Spectrometry 225\u003c\/p\u003e \u003cp\u003eChapter 18: Seeing Good Vibrations: IR Spectroscopy 241\u003c\/p\u003e \u003cp\u003eChapter 19: NMR Spectroscopy: Hold onto Your Hats, You’re Going Nuclear! 253\u003c\/p\u003e \u003cp\u003eChapter 20: Following the Clues: Solving Problems in NMR 273\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 5: The Part of Tens 293\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 21: Ten (Or So) Great Organic Chemists 295\u003c\/p\u003e \u003cp\u003eChapter 22: Ten Cool Organic Discoveries 301\u003c\/p\u003e \u003cp\u003eChapter 23: Ten Cool Organic Molecules 307\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 6: Appendixes 313\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAppendix A: Working Multistep Synthesis Problems 315\u003c\/p\u003e \u003cp\u003eAppendix B: Working Reaction Mechanisms 323\u003c\/p\u003e \u003cp\u003eAppendix C: Glossary 329\u003c\/p\u003e \u003cp\u003eIndex 339\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48866391851351,"sku":"9781119293378","price":16.14,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119293378.jpg?v=1722278430"},{"product_id":"browns-introduction-to-organic-chemistry-global-edition-9781119382881","title":"Browns Introduction to Organic Chemistry Global","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eBrown''s Introduction to Organic Chemistry\u003c\/i\u003e provides an introduction to organic chemistry for students who require the fundamentals of organic chemistry as a requirement for their major. It is most suited for a one semester organic chemistry course. In an attempt to highlight the relevance of the material to students, the authors place a strong emphasis on showing the interrelationship between organic chemistry and other areas of science, particularly the biological and health sciences. The text illustrates the use of organic chemistry as a tool in these sciences; it also stresses the organic compounds, both natural and synthetic, that surround us in everyday life: in pharmaceuticals, plastics, fibers, agrochemicals, surface coatings, toiletry preparations and cosmetics, food additives, adhesives, and elastomers.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003e1 Covalent Bonding and Shapes of Molecules 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 How Do We Describe the Electronic Structure of Atoms? 2\u003c\/p\u003e \u003cp\u003e1.2 What Is the Lewis Model of Bonding? 5\u003c\/p\u003e \u003cp\u003e1.3 How Do We Predict Bond Angles and the Shapes of Molecules? 13\u003c\/p\u003e \u003cp\u003e1.4 How Do We Predict If a Molecule Is Polar or Nonpolar? 17\u003c\/p\u003e \u003cp\u003e1.5 What Is Resonance? 18\u003c\/p\u003e \u003cp\u003e1.6 What Is the Orbital Overlap Model of Covalent Bonding? 21\u003c\/p\u003e \u003cp\u003e1.7 What Are Functional Groups? 26\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 31\u003c\/p\u003e \u003cp\u003eQuick Quiz 32\u003c\/p\u003e \u003cp\u003eProblems 34\u003c\/p\u003e \u003cp\u003eReal World Problems 37\u003c\/p\u003e \u003cp\u003eLooking Ahead 38\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 39\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1A Buckyball: A New Form of Carbon 16\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Acids and Bases 40\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 What Are Arrhenius Acids and Bases? 41\u003c\/p\u003e \u003cp\u003e2.2 What Are Brønsted–Lowry Acids and Bases? 42\u003c\/p\u003e \u003cp\u003e2.3 How Do We Measure the Strength of an Acid or Base? 44\u003c\/p\u003e \u003cp\u003e2.4 How Do We Determine the Position of Equilibrium in an Acid–Base Reaction? 46\u003c\/p\u003e \u003cp\u003e2.5 What Are the Relationships between Acidity and Molecular Structure? 48\u003c\/p\u003e \u003cp\u003e2.6 What Are Lewis Acids and Bases? 52\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 55\u003c\/p\u003e \u003cp\u003eQuick Quiz 56\u003c\/p\u003e \u003cp\u003eKey Reactions 57\u003c\/p\u003e \u003cp\u003eProblems 57\u003c\/p\u003e \u003cp\u003eReal World Problems 59\u003c\/p\u003e \u003cp\u003eLooking Ahead 59\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 60\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Alkanes and Cycloalkanes 61\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 What Are Alkanes? 62\u003c\/p\u003e \u003cp\u003e3.2 What Is Constitutional Isomerism in Alkanes? 64\u003c\/p\u003e \u003cp\u003e3.3 How Do We Name Alkanes? 66\u003c\/p\u003e \u003cp\u003e3.4 What Are Cycloalkanes? 71\u003c\/p\u003e \u003cp\u003e3.5 How Is the IUPAC System of Nomenclature Applied to Molecules that Contain Functional Groups? 72\u003c\/p\u003e \u003cp\u003e3.6 What Are the Conformations of Alkanes and Cycloalkanes? 73\u003c\/p\u003e \u003cp\u003e3.7 What Is Cis–Trans Isomerism in Cycloalkanes? 80\u003c\/p\u003e \u003cp\u003e3.8 What Are the Physical Properties of Alkanes and Cycloalkanes? 84\u003c\/p\u003e \u003cp\u003e3.9 What Are the Characteristic Reactions of Alkanes? 87\u003c\/p\u003e \u003cp\u003e3.10 What Are the Sources of Alkanes? 88\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 91\u003c\/p\u003e \u003cp\u003eQuick Quiz 92\u003c\/p\u003e \u003cp\u003eKey Reactions 93\u003c\/p\u003e \u003cp\u003eProblems 93\u003c\/p\u003e \u003cp\u003eReal World Problems 97\u003c\/p\u003e \u003cp\u003eLooking Ahead 98\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 99\u003c\/p\u003e \u003cp\u003ePutting it Together 99\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3A The Poisonous Puffer Fish 81\u003c\/p\u003e \u003cp\u003e3B Octane Rating: What Those Numbers at the Pump Mean 90\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Alkenes and Alkynes 103\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 What Are the Structures and Shapes of Alkenes and Alkynes? 105\u003c\/p\u003e \u003cp\u003e4.2 How Do We Name Alkenes and Alkynes? 107\u003c\/p\u003e \u003cp\u003e4.3 What Are the Physical Properties of Alkenes and Alkynes? 115\u003c\/p\u003e \u003cp\u003e4.4 Why Are 1-Alkynes (Terminal Alkynes) Weak Acids? 116\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 117\u003c\/p\u003e \u003cp\u003eQuick Quiz 118\u003c\/p\u003e \u003cp\u003eProblems 118\u003c\/p\u003e \u003cp\u003eReal World Problems 121\u003c\/p\u003e \u003cp\u003eLooking Ahead 122\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 122\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4A Ethylene, a Plant Growth Regulator 104\u003c\/p\u003e \u003cp\u003e4B Cis–Trans Isomerism in Vision 106\u003c\/p\u003e \u003cp\u003e4C Why Plants Emit Isoprene 115\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Reactions of Alkenes and Alkynes 123\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 What Are the Characteristic Reactions of Alkenes? 123\u003c\/p\u003e \u003cp\u003e5.2 What Is a Reaction Mechanism? 124\u003c\/p\u003e \u003cp\u003e5.3 What Are the Mechanisms of Electrophilic Additions to Alkenes? 130\u003c\/p\u003e \u003cp\u003e5.4 What Are Carbocation Rearrangements? 140\u003c\/p\u003e \u003cp\u003e5.5 What Is Hydroboration–Oxidation of an Alkene? 143\u003c\/p\u003e \u003cp\u003e5.6 How Can an Alkene Be Reduced to an Alkane? 145\u003c\/p\u003e \u003cp\u003e5.7 How Can an Acetylide Anion Be Used to Create a New Carbon–Carbon Bond? 148\u003c\/p\u003e \u003cp\u003e5.8 How Can Alkynes Be Reduced to Alkenes and Alkanes? 150\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 151\u003c\/p\u003e \u003cp\u003eQuick Quiz 152\u003c\/p\u003e \u003cp\u003eKey Reactions 153\u003c\/p\u003e \u003cp\u003eProblems 154\u003c\/p\u003e \u003cp\u003eChemical Transformation 157\u003c\/p\u003e \u003cp\u003eReal World Problems 158\u003c\/p\u003e \u003cp\u003eLooking Ahead 158\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 159\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5A Catalytic Cracking and the Importance of Alkenes 127\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Chirality: The Handedness of Molecules 160\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 What Are Stereoisomers? 161\u003c\/p\u003e \u003cp\u003e6.2 What Are Enantiomers? 161\u003c\/p\u003e \u003cp\u003e6.3 How Do We Designate the Configuration of a Stereocenter? 166\u003c\/p\u003e \u003cp\u003e6.4 What Is the 2n Rule? 168\u003c\/p\u003e \u003cp\u003e6.5 How Do We Describe the Chirality of Cyclic Molecules with Two Stereocenters? 172\u003c\/p\u003e \u003cp\u003e6.6 How Do We Describe the Chirality of Molecules with Three or More Stereocenters? 174\u003c\/p\u003e \u003cp\u003e6.7 What Are the Properties of Stereoisomers? 174\u003c\/p\u003e \u003cp\u003e6.8 How Is Chirality Detected in the Laboratory? 175\u003c\/p\u003e \u003cp\u003e6.9 What Is the Significance of Chirality in the Biological World? 176\u003c\/p\u003e \u003cp\u003e6.10 How Can Enantiomers Be Resolved? 177\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 179\u003c\/p\u003e \u003cp\u003eQuick Quiz 180\u003c\/p\u003e \u003cp\u003eProblems 181\u003c\/p\u003e \u003cp\u003eChemical Transformations 184\u003c\/p\u003e \u003cp\u003eReal World Problems 185\u003c\/p\u003e \u003cp\u003eLooking Ahead 186\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 187\u003c\/p\u003e \u003cp\u003ePutting it Together 187\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6A Chiral Drugs 178\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Haloalkanes 190\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 How Are Haloalkanes Named? 191\u003c\/p\u003e \u003cp\u003e7.2 What Are the Characteristic Reactions of Haloalkanes? 193\u003c\/p\u003e \u003cp\u003e7.3 What Are the Products of Nucleophilic Aliphatic Substitution Reactions? 195\u003c\/p\u003e \u003cp\u003e7.4 What Are the S\u003csub\u003eN\u003c\/sub\u003e2 and S\u003csub\u003eN\u003c\/sub\u003e1 Mechanisms for Nucleophilic Substitution? 197\u003c\/p\u003e \u003cp\u003e7.5 What Determines Whether S\u003csub\u003eN\u003c\/sub\u003e1 or S\u003csub\u003eN\u003c\/sub\u003e2 Predominates? 201\u003c\/p\u003e \u003cp\u003e7.6 How Can S\u003csub\u003eN\u003c\/sub\u003e1 and S\u003csub\u003eN\u003c\/sub\u003e2 Be Predicted Based on Experimental Conditions? 206\u003c\/p\u003e \u003cp\u003e7.7 What Are the Products of \u003ci\u003eβ\u003c\/i\u003e‐Elimination? 208\u003c\/p\u003e \u003cp\u003e7.8 What Are the E1 and E2 Mechanisms for \u003ci\u003eβ\u003c\/i\u003e‐Elimination? 211\u003c\/p\u003e \u003cp\u003e7.9 When Do Nucleophilic Substitution and \u003ci\u003eβ\u003c\/i\u003e‐Elimination Compete? 214\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 217\u003c\/p\u003e \u003cp\u003eQuick Quiz 218\u003c\/p\u003e \u003cp\u003eKey Reactions 218\u003c\/p\u003e \u003cp\u003eProblems 219\u003c\/p\u003e \u003cp\u003eChemical Transformations 223\u003c\/p\u003e \u003cp\u003eLooking Ahead 224\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 225\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7A The Environmental Impact of Chlorofluorocarbons 193\u003c\/p\u003e \u003cp\u003e7B The Effect of Chlorofluorocarbon Legislation on Asthma Sufferers 216\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Alcohols, Ethers, and Thiols 226\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 What Are Alcohols? 227\u003c\/p\u003e \u003cp\u003e8.2 What Are the Characteristic Reactions of Alcohols? 232\u003c\/p\u003e \u003cp\u003e8.3 What Are Ethers? 245\u003c\/p\u003e \u003cp\u003e8.4 What Are Epoxides? 249\u003c\/p\u003e \u003cp\u003e8.5 What Are Thiols? 253\u003c\/p\u003e \u003cp\u003e8.6 What Are the Characteristic Reactions of Thiols? 256\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 257\u003c\/p\u003e \u003cp\u003eQuick Quiz 258\u003c\/p\u003e \u003cp\u003eKey Reactions 259\u003c\/p\u003e \u003cp\u003eProblems 260\u003c\/p\u003e \u003cp\u003eChemical Transformations 263\u003c\/p\u003e \u003cp\u003eReal World Problems 264\u003c\/p\u003e \u003cp\u003eLooking Ahead 264\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 265\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8A Nitroglycerin: An Explosive and a Drug 230\u003c\/p\u003e \u003cp\u003e8B Blood Alcohol Screening 245\u003c\/p\u003e \u003cp\u003e8C Ethylene Oxide: A Chemical Sterilant 253\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Benzene and Its Derivatives 266\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 What Is the Structure of Benzene? 267\u003c\/p\u003e \u003cp\u003e9.2 What Is Aromaticity? 270\u003c\/p\u003e \u003cp\u003e9.3 How Are Benzene Compounds Named, and What Are Their Physical Properties? 273\u003c\/p\u003e \u003cp\u003e9.4 What Is a Benzylic Position, and How Does It Contribute to Benzene Reactivity? 276\u003c\/p\u003e \u003cp\u003e9.5 What Is Electrophilic Aromatic Substitution? 278\u003c\/p\u003e \u003cp\u003e9.6 What Is the Mechanism of Electrophilic Aromatic Substitution? 279\u003c\/p\u003e \u003cp\u003e9.7 How Do Existing Substituents on Benzene Affect Electrophilic Aromatic Substitution? 288\u003c\/p\u003e \u003cp\u003e9.8 What Are Phenols? 296\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 303\u003c\/p\u003e \u003cp\u003eQuick Quiz 304\u003c\/p\u003e \u003cp\u003eKey Reactions 304\u003c\/p\u003e \u003cp\u003eProblems 305\u003c\/p\u003e \u003cp\u003eChemical Transformations 309\u003c\/p\u003e \u003cp\u003eReal World Problems 310\u003c\/p\u003e \u003cp\u003eLooking Ahead 311\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 312\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9A Carcinogenic Polynuclear Aromatics and Cancer 277\u003c\/p\u003e \u003cp\u003e9B Capsaicin, for Those Who Like It Hot 300\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Amines 313\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 What Are Amines? 313\u003c\/p\u003e \u003cp\u003e10.2 How Are Amines Named? 316\u003c\/p\u003e \u003cp\u003e10.3 What Are the Characteristic Physical Properties of Amines? 319\u003c\/p\u003e \u003cp\u003e10.4 What Are the Acid–Base Properties of Amines? 321\u003c\/p\u003e \u003cp\u003e10.5 What Are the Reactions of Amines with Acids? 325\u003c\/p\u003e \u003cp\u003e10.6 How Are Arylamines Synthesized? 327\u003c\/p\u003e \u003cp\u003e10.7 How Do Amines Act as Nucleophiles? 328\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 330\u003c\/p\u003e \u003cp\u003eQuick Quiz 331\u003c\/p\u003e \u003cp\u003eKey Reactions 331\u003c\/p\u003e \u003cp\u003eProblems 332\u003c\/p\u003e \u003cp\u003eChemical Transformations 334\u003c\/p\u003e \u003cp\u003eReal World Problems 335\u003c\/p\u003e \u003cp\u003eLooking Ahead 337\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 337\u003c\/p\u003e \u003cp\u003ePutting it Together 338\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10A Morphine as a Clue in the Design and Discovery of Drugs 314\u003c\/p\u003e \u003cp\u003e10B The Poison Dart Frogs of South America: Lethal Amines 319\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Spectroscopy 341\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 What Is Electromagnetic Radiation? 342\u003c\/p\u003e \u003cp\u003e11.2 What Is Molecular Spectroscopy? 344\u003c\/p\u003e \u003cp\u003e11.3 What Is Infrared Spectroscopy? 344\u003c\/p\u003e \u003cp\u003e11.4 How Do We Interpret Infrared Spectra? 347\u003c\/p\u003e \u003cp\u003e11.5 What Is Nuclear Magnetic Resonance? 358\u003c\/p\u003e \u003cp\u003e11.6 What Is Shielding? 360\u003c\/p\u003e \u003cp\u003e11.7 What Is a \u003csup\u003e1\u003c\/sup\u003eH-NMR Spectrum? 360\u003c\/p\u003e \u003cp\u003e11.8 How Many Resonance Signals Will a Compound Yield in Its \u003csup\u003e1\u003c\/sup\u003eH‐NMR Spectrum? 362\u003c\/p\u003e \u003cp\u003e11.9 What Is Signal Integration? 365\u003c\/p\u003e \u003cp\u003e11.10 What Is Chemical Shift? 366\u003c\/p\u003e \u003cp\u003e11.11 What Is Signal Splitting? 368\u003c\/p\u003e \u003cp\u003e11.12 What Is \u003csup\u003e13\u003c\/sup\u003eC‐NMR Spectroscopy, and How Does It Differ from \u003csup\u003e1\u003c\/sup\u003eH‐NMR Spectroscopy? 371\u003c\/p\u003e \u003cp\u003e11.13 How Do We Solve an NMR Problem? 374\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 378\u003c\/p\u003e \u003cp\u003eQuick Quiz 380\u003c\/p\u003e \u003cp\u003eProblems 381\u003c\/p\u003e \u003cp\u003eReal World Problems 393\u003c\/p\u003e \u003cp\u003eLooking Ahead 394\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 395\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11A Infrared Spectroscopy: A Window on Brain Activity 348\u003c\/p\u003e \u003cp\u003e11B Infrared Spectroscopy: A Window on Climate Change 354\u003c\/p\u003e \u003cp\u003e11C Magnetic Resonance Imaging (MRI) 371\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Aldehydes and Ketones 396\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 What Are Aldehydes and Ketones? 397\u003c\/p\u003e \u003cp\u003e12.2 How Are Aldehydes and Ketones Named? 397\u003c\/p\u003e \u003cp\u003e12.3 What Are the Physical Properties of Aldehydes and Ketones? 401\u003c\/p\u003e \u003cp\u003e12.4 What Is the Most Common Reaction Theme of Aldehydes and Ketones? 402\u003c\/p\u003e \u003cp\u003e12.5 What Are Grignard Reagents, and How Do They React with Aldehydes and Ketones? 402\u003c\/p\u003e \u003cp\u003e12.6 What Are Hemiacetals and Acetals? 407\u003c\/p\u003e \u003cp\u003e12.7 How Do Aldehydes and Ketones React with Ammonia and Amines? 413\u003c\/p\u003e \u003cp\u003e12.8 What Is Keto‐Enol Tautomerism? 417\u003c\/p\u003e \u003cp\u003e12.9 How Are Aldehydes and Ketones Oxidized? 420\u003c\/p\u003e \u003cp\u003e12.10 How Are Aldehydes and Ketones Reduced? 423\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 425\u003c\/p\u003e \u003cp\u003eQuick Quiz 426\u003c\/p\u003e \u003cp\u003eKey Reactions 427\u003c\/p\u003e \u003cp\u003eProblems 428\u003c\/p\u003e \u003cp\u003eChemical Transformations 431\u003c\/p\u003e \u003cp\u003eSpectroscopy 432\u003c\/p\u003e \u003cp\u003eReal World Problems 433\u003c\/p\u003e \u003cp\u003eLooking Ahead 435\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 436\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12A A Green Synthesis of Adipic Acid 422\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Carboxylic Acids 437\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 What Are Carboxylic Acids? 437\u003c\/p\u003e \u003cp\u003e13.2 How Are Carboxylic Acids Named? 438\u003c\/p\u003e \u003cp\u003e13.3 What Are the Physical Properties of Carboxylic Acids? 441\u003c\/p\u003e \u003cp\u003e13.4 What Are the Acid–Base Properties of Carboxylic Acids? 442\u003c\/p\u003e \u003cp\u003e13.5 How Are Carboxyl Groups Reduced? 446\u003c\/p\u003e \u003cp\u003e13.6 What Is Fischer Esterification? 449\u003c\/p\u003e \u003cp\u003e13.7 What Are Acid Chlorides? 453\u003c\/p\u003e \u003cp\u003e13.8 What Is Decarboxylation? 455\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 459\u003c\/p\u003e \u003cp\u003eQuick Quiz 459\u003c\/p\u003e \u003cp\u003eKey Reactions 460\u003c\/p\u003e \u003cp\u003eProblems 461\u003c\/p\u003e \u003cp\u003eChemical Transformations 464\u003c\/p\u003e \u003cp\u003eReal World Problems 464\u003c\/p\u003e \u003cp\u003eLooking Ahead 467\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 467\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13A From Willow Bark to Aspirin and Beyond 446\u003c\/p\u003e \u003cp\u003e13B Esters as Flavoring Agents 451\u003c\/p\u003e \u003cp\u003e13C Ketone Bodies and Diabetes 456\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Functional Derivatives of Carboxylic Acids 468\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 What Are Some Derivatives of Carboxylic Acids, and How Are They Named? 469\u003c\/p\u003e \u003cp\u003e14.2 What Are the Characteristic Reactions of Carboxylic Acid Derivatives? 474\u003c\/p\u003e \u003cp\u003e14.3 What Is Hydrolysis? 475\u003c\/p\u003e \u003cp\u003e14.4 How Do Carboxylic Acid Derivatives React with Alcohols? 480\u003c\/p\u003e \u003cp\u003e14.5 How Do Carboxylic Acid Derivatives React with Ammonia and Amines? 483\u003c\/p\u003e \u003cp\u003e14.6 How Can Functional Derivatives of Carboxylic Acids Be Interconverted? 485\u003c\/p\u003e \u003cp\u003e14.7 How Do Esters React with Grignard Reagents? 486\u003c\/p\u003e \u003cp\u003e14.8 How Are Derivatives of Carboxylic Acids Reduced? 488\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 492\u003c\/p\u003e \u003cp\u003eQuick Quiz 493\u003c\/p\u003e \u003cp\u003eKey Reactions 493\u003c\/p\u003e \u003cp\u003eProblems 495\u003c\/p\u003e \u003cp\u003eChemical Transformations 498\u003c\/p\u003e \u003cp\u003eReal World Problems 498\u003c\/p\u003e \u003cp\u003eLooking Ahead 501\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 501\u003c\/p\u003e \u003cp\u003ePutting it Together 501\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14A Ultraviolet Sunscreens and Sunblocks 470\u003c\/p\u003e \u003cp\u003e14B From Moldy Clover to a Blood Thinner 471\u003c\/p\u003e \u003cp\u003e14C The Penicillins and Cephalosporins: \u003ci\u003eβ\u003c\/i\u003e‐Lactam Antibiotics 472\u003c\/p\u003e \u003cp\u003e14D The Pyrethrins: Natural Insecticides of Plant Origin 482\u003c\/p\u003e \u003cp\u003e14E Systematic Acquired Resistance in Plants 485\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Enolate Anions 504\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 What Are Enolate Anions, and How Are They Formed? 505\u003c\/p\u003e \u003cp\u003e15.2 What Is the Aldol Reaction? 508\u003c\/p\u003e \u003cp\u003e15.3 What Are the Claisen and Dieckmann Condensations? 515\u003c\/p\u003e \u003cp\u003e15.4 How Are Aldol Reactions and Claisen Condensations Involved in Biological Processes? 522\u003c\/p\u003e \u003cp\u003e15.5 What Is the Michael Reaction? 524\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 531\u003c\/p\u003e \u003cp\u003eQuick Quiz 531\u003c\/p\u003e \u003cp\u003eKey Reactions 532\u003c\/p\u003e \u003cp\u003eProblems 533\u003c\/p\u003e \u003cp\u003eChemical Transformations 536\u003c\/p\u003e \u003cp\u003eReal World Problems 537\u003c\/p\u003e \u003cp\u003eLooking Ahead 540\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 541\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15A Drugs That Lower Plasma Levels of Cholesterol 523\u003c\/p\u003e \u003cp\u003e15B Antitumor Compounds: The Michael Reaction in Nature 530\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Organic Polymer Chemistry 542\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 What Is the Architecture of Polymers? 543\u003c\/p\u003e \u003cp\u003e16.2 How Do We Name and Show the Structure of a Polymer? 543\u003c\/p\u003e \u003cp\u003e16.3 What Is Polymer Morphology? Crystalline versus Amorphous Materials 545\u003c\/p\u003e \u003cp\u003e16.4 What Is Step‐Growth Polymerization? 546\u003c\/p\u003e \u003cp\u003e16.5 What Are Chain‐Growth Polymers? 551\u003c\/p\u003e \u003cp\u003e16.6 What Plastics Are Currently Recycled in Large Quantities? 557\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 558\u003c\/p\u003e \u003cp\u003eQuick Quiz 559\u003c\/p\u003e \u003cp\u003eKey Reactions 560\u003c\/p\u003e \u003cp\u003eProblems 560\u003c\/p\u003e \u003cp\u003eReal World Problem 562\u003c\/p\u003e \u003cp\u003eLooking Ahead 562\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 562\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16A Stitches That Dissolve 551\u003c\/p\u003e \u003cp\u003e16B Paper or Plastic? 553\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Carbohydrates 563\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17.1 What Are Carbohydrates? 563\u003c\/p\u003e \u003cp\u003e17.2 What Are Monosaccharides? 564\u003c\/p\u003e \u003cp\u003e17.3 What Are the Cyclic Structures of Monosaccharides? 568\u003c\/p\u003e \u003cp\u003e17.4 What Are the Characteristic Reactions of Monosaccharides? 573\u003c\/p\u003e \u003cp\u003e17.5 What Are Disaccharides and Oligosaccharides? 577\u003c\/p\u003e \u003cp\u003e17.6 What Are Polysaccharides? 581\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 583\u003c\/p\u003e \u003cp\u003eQuick Quiz 584\u003c\/p\u003e \u003cp\u003eKey Reactions 585\u003c\/p\u003e \u003cp\u003eProblems 586\u003c\/p\u003e \u003cp\u003eReal World Problems 588\u003c\/p\u003e \u003cp\u003eLooking Ahead 590\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 591\u003c\/p\u003e \u003cp\u003ePutting it Together 591\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17A Relative Sweetness of Carbohydrate and Artificial Sweeteners 578\u003c\/p\u003e \u003cp\u003e17B A, B, AB, and O Blood‐Group Substances 579\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Amino Acids and Proteins 595\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18.1 What Are the Many Functions of Proteins? 595\u003c\/p\u003e \u003cp\u003e18.2 What Are Amino Acids? 596\u003c\/p\u003e \u003cp\u003e18.3 What Are the Acid–Base Properties of Amino Acids? 599\u003c\/p\u003e \u003cp\u003e18.4 What Are Polypeptides and Proteins? 606\u003c\/p\u003e \u003cp\u003e18.5 What Is the Primary Structure of a Polypeptide or Protein? 607\u003c\/p\u003e \u003cp\u003e18.6 What Are the Three‐Dimensional Shapes of Polypeptides and Proteins? 611\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 618\u003c\/p\u003e \u003cp\u003eQuick Quiz 619\u003c\/p\u003e \u003cp\u003eKey Reactions 620\u003c\/p\u003e \u003cp\u003eProblems 620\u003c\/p\u003e \u003cp\u003eReal World Problems 622\u003c\/p\u003e \u003cp\u003eLooking Ahead 623\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 623\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18A Spider Silk: A Chemical and Engineering Wonder of Nature 616\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Lipids (Online Chapter) 624\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19.1 What Are Triglycerides? 624\u003c\/p\u003e \u003cp\u003e19.2 What Are Soaps and Detergents? 628\u003c\/p\u003e \u003cp\u003e19.3 What Are Phospholipids? 630\u003c\/p\u003e \u003cp\u003e19.4 What Are Steroids? 632\u003c\/p\u003e \u003cp\u003e19.5 What Are Prostaglandins? 637\u003c\/p\u003e \u003cp\u003e19.6 What Are Fat‐Soluble Vitamins? 640\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 643\u003c\/p\u003e \u003cp\u003eQuick Quiz 644\u003c\/p\u003e \u003cp\u003eProblems 644\u003c\/p\u003e \u003cp\u003eReal World Problems 646\u003c\/p\u003e \u003cp\u003eLooking Ahead 646\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 647\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19A Snake Venom Phospholipases 632\u003c\/p\u003e \u003cp\u003e19B Nonsteroidal Estrogen Antagonists 636\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Nucleic Acids (Online Chapter) 648\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20.1 What Are Nucleosides and Nucleotides? 648\u003c\/p\u003e \u003cp\u003e20.2 What Is the Structure of DNA? 652\u003c\/p\u003e \u003cp\u003e20.3 What Are Ribonucleic Acids (RNA)? 658\u003c\/p\u003e \u003cp\u003e20.4 What Is the Genetic Code? 660\u003c\/p\u003e \u003cp\u003e20.5 How Is DNA Sequenced? 662\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 667\u003c\/p\u003e \u003cp\u003eQuick Quiz 668\u003c\/p\u003e \u003cp\u003eProblems 669\u003c\/p\u003e \u003cp\u003eReal World Problems 671\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 671\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChemical Connections\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20A The Search for Antiviral Drugs 650\u003c\/p\u003e \u003cp\u003e20B DNA Fingerprinting 666\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 The Organic Chemistry of Metabolism (Online Chapter) 672\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e21.1 What Are the Key Participants in Glycolysis, the β‐Oxidation of Fatty Acids, and the Citric Acid Cycle? 673\u003c\/p\u003e \u003cp\u003e21.2 What Is Glycolysis? 678\u003c\/p\u003e \u003cp\u003e21.3 What Are the Ten Reactions of Glycolysis? 678\u003c\/p\u003e \u003cp\u003e21.4 What Are the Fates of Pyruvate? 683\u003c\/p\u003e \u003cp\u003e21.5 What Are the Reactions of the \u003ci\u003eβ\u003c\/i\u003e‐Oxidation of Fatty Acids? 685\u003c\/p\u003e \u003cp\u003e21.6 What Are the Reactions of the Citric Acid Cycle? 689\u003c\/p\u003e \u003cp\u003eSummary of Key Questions 692\u003c\/p\u003e \u003cp\u003eQuick Quiz 693\u003c\/p\u003e \u003cp\u003eKey Reactions 693\u003c\/p\u003e \u003cp\u003eProblems 694\u003c\/p\u003e \u003cp\u003eReal World Problems 695\u003c\/p\u003e \u003cp\u003eGroup Learning Activities 696\u003c\/p\u003e \u003cp\u003eAppendix 1 Acid Ionization Constants for the Major Classes of Organic Acids A.1\u003c\/p\u003e \u003cp\u003eCharacteristic \u003csup\u003e1\u003c\/sup\u003eH‐NMR Chemical Shifts A.1\u003c\/p\u003e \u003cp\u003eAppendix 2 Characteristic \u003csup\u003e13\u003c\/sup\u003eC‐NMR Chemical Shifts A.2\u003c\/p\u003e \u003cp\u003eCharacteristic Infrared Absorption Frequencies A.2\u003c\/p\u003e \u003cp\u003eGlossary G.1\u003c\/p\u003e \u003cp\u003eAnswers Section Ans.1\u003c\/p\u003e \u003cp\u003eIndex I.1\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48866394112343,"sku":"9781119382881","price":50.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119382881.jpg?v=1722278443"},{"product_id":"organic-chemistry-digital-update-international-edition-9781319467975","title":"Organic Chemistry Digital Update International","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Macmillan Learning","offers":[{"title":"Default Title","offer_id":48866558476631,"sku":"9781319467975","price":72.19,"currency_code":"GBP","in_stock":true}]},{"product_id":"laboratory-techniques-in-organic-chemistry-9781464134227","title":"Laboratory Techniques in Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eReceive a detailed and comprehensive breakdown of the lab techniques all organic chemistry students need to know with \u003cem\u003eLaboratory Techniques in Organic Chemistry.\u003c\/em\u003e","brand":"Macmillan Learning","offers":[{"title":"Default Title","offer_id":48867162980695,"sku":"9781464134227","price":80.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781464134227.jpg?v=1722281977"},{"product_id":"modern-physical-organic-chemistry-9781891389313","title":"Modern Physical Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"University Science Books,U.S.","offers":[{"title":"Default Title","offer_id":48868861903191,"sku":"9781891389313","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"fundamentals-of-chemistry-for-today-9780357453421","title":"Fundamentals of Chemistry for Today","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSeager\/Rye-McCurdy\/Yoder's FUNDAMENTALS OF CHEMISTRY FOR TODAY helps you hone your critical-thinking skills with ample problem-solving opportunities throughout the text. Fresh examples won't bog you down with incessant repetition, and new figures relevant to health professions add context and color to the core source material. FUNDAMENTALS OF CHEMISTRY FOR TODAY covers all the necessary components of the GOB curriculum in sufficient depth to prepare you for future studies.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Matter, Measurements, and Calculations. 2. Atomic Structure and the Periodic Table. 3. Chemical Bonds: Molecule Formation. 4. The Mole and Chemical Reactions. 5: Molecular Shapes and Intermolecular Forces. 6. Gasses. 7. Acids, Bases, and Buffers. 8. Introduction to Organic Chemistry: Hydrocarbons. 9. Alcohols, Ethers, and Amines. 10. Carbonyl Compounds. 11. Carbohydrates. 12. Amino Acids and Proteins. 13. Nucleic Acids and Protein Synthesis. 14. Lipids. 15. Nutrition and Metabolism.","brand":"Cengage Learning, Inc","offers":[{"title":"Default Title","offer_id":48884044661079,"sku":"9780357453421","price":74.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"metals-and-chemical-change-9780854046652","title":"Metals and Chemical Change","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book looks at how molecules react, and how the feasibility and outcome of chemical reactions can be predicted. Beginning with an introduction to the concept of an activity series of metals, Metals and Chemical Change then introduces chemical thermodynamics (enthalpy, entropy and free energy) and applies the concept to both inorganic and organic elements. A Case Study on batteries and fuel cells is also included. The accompanying CD-ROM includes video sequences of the reactions of metals with water, acid and aqueous ions, and gives the reader an opportunity to make experimental observations and predictions about chemical behaviour. A comprehensive Data Book of chemical and physical constants is included, along with a set of interactive self-assessment questions. The Molecular World series provides an integrated introduction to all branches of chemistry for both students wishing to specialise and those wishing to gain a broad understanding of chemistry and its relevance to the every\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"The book and CD-ROM provide an excellent learning resource of the material covered ... strongly recommended.\" * Physical Sciences Educational Reviews, No 6, June 2003 *\u003cbr\u003e\"One of the many highlights of the book is the use of everyday examples of metals and their reactivity, particularly industrial examples ... The CD contains some excellent video sequences ...\" * Australian Journal of Chemistry, 2002, 55, 487-489 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction; Reactions of Metals; Metals and their Ores; Metals and their Ease of Oxidation: A Hypothesis; Equilibrium: A Restatement of the Problem; Thomsen's Hypothesis: Towards a Solution?; The Second Law of Thermodynamics: The Solution; The First Law of Thermodynamics; Enthalpies of Reaction: A Database; Entropy Changes; The Gibbs Function; Metals and their Ease of Oxidation; Thermodynamic and Kinetic Stability; Reactivity; Thermodynamics and the Oxidation of Metals; Enthalpy and Entropy Terms; Metals and their Ores; The Born-Haber Cycle; Introduction to the Remaining Sections; The Lattice Energy; Electrochemical Cells and Redox Potentials; Ionization Energies of Atoms; The Chemistry of Group I: The Alkali Elements; Alkali Metal Compounds in Industry; Binary Alkali Metal Compounds with Non-metals; Metal Ions, Ligands and Complexes; Alkali Metal Complexes; The Group II or Alkaline Earth Elements; Case Study: Batteries and Fuel Cells.","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48884780237143,"sku":"9780854046652","price":24.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780854046652.jpg?v=1722533429"},{"product_id":"chemistry-of-fragrances-9780854048243","title":"Chemistry of Fragrances","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eModern perfumery is a blend of art, science and technology, with chemistry being the central science involved. The Chemistry of Fragrances aims to educate and entertain, and inform the audience of the very latest chemistry, techniques and tools applied to fragrance creativity. Beginning with the history of perfumes, which goes back over fifty thousand years, the book goes on to discuss the structure of the Perfume Industry today. The focus then turns to an imaginary brief to create a perfume, and the response to it, including that of the chemist and the creative perfumer. Consumer research, toxicological concerns, and the use of the electronic nose are some of the topics discussed on this journey of discovery. Written by respected experts in their fields, this unique book gives an insider view of mixing molecules from behind the portals of modern-day alchemy. It will be enjoyed by chemists and marketeers at all levels.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eA concise approach to cover the multi-facets of the science of fragrance...as a useful introduction to the chemistry of fragrance. -- Chemistry and Industry, 9 July 2007 (Thomas McGee) Chemistry and Industry The authors are able to demonstrate that the chemistry of such tiny fragrant molecules can be very fascinating...the book is a must for anyone with an interest in fragrances. It is simply fascinating!! -- Flavour and Fragrance Journal, 2008, 23:66 (Gerhard Buchbauer) Flavour and Fragrance Journal\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eA Home Full of Fragrance; The History of Aroma Chemistry and Perfume; Perfumery Materials of Natural Origin; Ingredients for the Modern Perfumery Industry; The Structure of an International Fragrance Company; The Fragrance Brief; Perfume Creation - The Role of the Perfumer; Measurement of Fragrance Perception; Application of Fragrances; The Safety and Toxicology of Fragrances; Volatility and Substantivity; Natural Product Analysis in the Fragrance Industry; Chemoreception; Electronic Odour Sensing; The Quest for Novel Aroma Chemicals; Brief Submission; Epilogue; Glossary of Terms; Bibliography; Index; Useful Addresses; Djinn's Lamp.","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48884780335447,"sku":"9780854048243","price":28.45,"currency_code":"GBP","in_stock":true}]},{"product_id":"techniques-and-experiments-for-organic-chemistry-9780935702767","title":"Techniques and Experiments For Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Scion Publishing","offers":[{"title":"Default Title","offer_id":48885047263575,"sku":"9780935702767","price":114.72,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780935702767.jpg?v=1722534660"},{"product_id":"organic-chemistry-ise-9781266223938","title":"Organic Chemistry ISE","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eOrganic Chemistry\u003c\/i\u003e, Seventh Edition, continues the successful student-oriented approach used in prior editions. This text uses less prose and more diagrams and bulleted summaries for today's students, who rely more heavily on visual imagery to learn than ever before. Each topic is broken down into small chunks of information that are more manageable and easily learned.\u003cbr\u003e\u003cbr\u003eOrganic chemistry is a dynamic subject that is continually refined as new facts are determined. Each year, novel compounds are discovered, and new drugs are marketed, and these compounds replace older examples to illustrate particular concepts. In this edition, for example, every effort has been made to include content on COVID-19.\u003cbr\u003e\u003cbr\u003eThe text is strengthened by its offering in ALEKS, now featuring Custom Question Authoring, Video Assignments, Virtual Labs, and more!\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eChapter 1: Structure and Bonding\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 2: Acids and Bases\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 3: Introduction to Organic Molecules and Functional Groups\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 4: Alkanes\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 5: Stereochemistry\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 6: Understanding Organic Reactions\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 7: Alkyl Halides and Nucleophilic Substitution\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 8: Alkyl Halides and Elimination Reactions\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 9: Alcohols, Ethers, and Related Compounds\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 10: Alkenes and Addition Reactions\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 11: Alkynes and Synthesis\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 12: Oxidation and Reduction\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSpectroscopy A Mass Spectrometry\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSpectroscopy B Infrared Spectroscopy\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSpectroscopy C Nuclear Magnetic Resonance Spectroscopy\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 13: Radical Reactions\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 14: Conjugation, Resonance, and Dienes\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 15: Benzene and Aromatic Compounds\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 16: Reactions of Aromatic Compounds\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 17: Introduction to Carbonyl Chemistry: Organometallic Reagents; Oxidation and Reduction\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 18: Aldehydes and Ketones—Nucleophilic Addition\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 19: Carboxylic Acids and Nitriles\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 20: Carboxylic Acids and Their Derivatives- Nucleophilic Acyl Substitution\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 21: Substitution Reactions of Carbonyl Compounds at the α-Carbon\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 22: Carbonyl Condensation Reactions\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 23: Amines\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 24: Carbon-Carbon Bond-Forming Reactions in Organic Synthesis\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 25: Pericyclic Reactions\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 26: Carbohydrates\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 27: Amino Acids and Proteins\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 28: Nucleic Acids and Protein Synthesis\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 29: Lipids (Available Online)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 30: Metabolism (Available Online)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eChapter 31: Synthetic Polymers (Available Online)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"McGraw-Hill Education","offers":[{"title":"Default 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