{"title":"Molecular biology Books","description":"","products":[{"product_id":"what-do-you-think-you-are-the-science-of-what-makes-you-you-9781785786600","title":"What Do You Think You Are?: The Science of What","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003e'Gets right to the heart of what makes us what we are. Read it!' Angela Saini, author of \u003ci\u003eInferior and Superior: The Return of Race Science\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eThe popular science equivalent of \u003ci\u003eWho Do You Think You Are? \u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003ePopular science master Brian Clegg's new book is an entertaining tour through the science of what makes you you.\u003cbr\u003e\u003cbr\u003eFrom the atomic level, through life and energy to genetics and personality, it explores how the billions of particles which make up you - your DNA, your skin, your memories - have come to be.\u003cbr\u003e\u003cbr\u003eIt starts with the present-day reader and follows a number of trails to discover their origins: how the atoms in your body were created and how they got to you in space and time, the sources of things you consume, how the living cells of your body developed, where your massive brain and consciousness originated, how human beings evolved and, ultimately, what your personal genetic history reveals.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eWhat's great about the book overall is both Clegg's gift as a storyteller - it's just an excellent, pageturning read - and the way he threads together so many revelations about us as humans, the sort of thing that you want to share with someone else. * popularscience.co.uk *\u003cbr\u003eThe most interesting part is when the book explores what consciousness is (or, rather, highlights how little we know about it but still shows how much more there is to \"us\" than the conscious part) and pulls apart the old nature versus nurture debate with some remarkable material on genetics and how the influence of our environment is mathematically chaotic. * Peet Morris, Times Higher Education *","brand":"Icon Books","offers":[{"title":"Default Title","offer_id":47851264639319,"sku":"9781785786600","price":9.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781785786600.jpg?v=1710631710"},{"product_id":"the-chemistry-of-life-9780140272734","title":"The Chemistry of Life","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eFirst published in 1966, THE CHEMISTRY OF LIFE has held its own as a clear and authoritative introduction to the world of biochemistry. This fourth edition has been fully updated and revised to include the latest developments in DNA and protein synthesis, cell regulation, and their social and medical implications.","brand":"Penguin Books Ltd","offers":[{"title":"Default Title","offer_id":48732351791447,"sku":"9780140272734","price":11.69,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780140272734.jpg?v=1719996527"},{"product_id":"insulin-the-crooked-timber-9780192855381","title":"Insulin  The Crooked Timber","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eBefore the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. One hundred years after a milestone medical discovery, ''Insulin - The Crooked Timber'' tells the story of how insulin was transformed from what one clinician called ''thick brown muck'' into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune.Yet when Canadian doctor Frederick Banting was told in 1923 that he had won the Nobel Prize for this life-saving discovery, he was furious. For the prize had not been awarded to him alone - but jointly with a man whom he felt had no right to this honour. The human story behind this discovery is one of ongoing political and scientific controversy.Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, ''Insulin - The Crooked Timber'' reveals a story of monstrous egos, toxic career rivalries, and a few \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e[uses] a blend of profound research, lively writing and personal knowledge of diabetes * Andrew Robinson, Nature *\u003cbr\u003eThe lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account. * Arpan K. Banerjee, Hektoen International *\u003cbr\u003eThe story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare.[...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health. * Steven Poole, Daily Telegraph *\u003cbr\u003e... comprehensive account of the modern medical history of the hormone... * Jerome Groopman, New York Review of Books *\u003cbr\u003eA fascinating book by an author with excellent credentials, well written and meticulously researched. * Geoff Gill, University of Liverpool *\u003cbr\u003eA timely book, pulling together many interesting stories about the scientific side of insulin. * John Pickup, King's College London School of Medicine *\u003cbr\u003eReviews the events around the discovery of insulin in an original and well-documented manner. * Pierre Lefèbvre, University of Liège *\u003cbr\u003eWritten in a clear and engaging style, the book provides a fresh take on historic events and also delves into aspects that have not been adequately explored previously. * Jeffrey Friedman, Rockefeller University *\u003cbr\u003eIt is a good read and scholarly account. * Arpan Banerjee, Hektoen International Journal *\u003cbr\u003eInsulin-the Crooked Timber is essential reading for anyone concerned with the history of insulin. * Social History of Alcohol and Drugs. *\u003cbr\u003eHall's The Crooked Timber expertly combines careful attention to the science with thoughtful consideration of its historical and philosophical dimensions. * Neelanjana Ray, History and Philosophy of the Life Sciences *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface Looking a Gift Horse in the Mouth? Introduction Taming the Tiger 1: The Pissing Evil - a colourful description of diabetes by 17th century English physician Thomas Willis 2: Thick Brown Muck - Canadian scientist Fred Banting wins the Nobel Prize for the discovery of insulin... and is furious 3: The Vision of Ezekiel - clinicians are stunned at the power of insulin to save lives, but it proves to be a double-edged sword 4: A Greek Tragedy - German clinician Georg Zuelzer snatches defeat from the jaws of victory 5: The Wasp's Nest - insulin proves to be a poisoned chalice for its discoverers 6: Be Careful What You Wish For - the case of Romanian scientist Nicolai Paulesco underlines the truth of an old proverb 7: 'In Praise of Wool' - the humble wool fibre sets in motion a revolution in biochemistry 8: A Boastful Undertaking - a discovery made in a fume-filled stable offers the key to unlocking insulin 9: The Blobs That Won a Nobel Prize - or two, all thanks to some coloured spots on a piece of filter paper 10: The Prophet in the Labyrinth - biochemist Erwin Chargaff helps unlock the secrets of DNA, but fears where this may lead 11: The Clone Wars - a conflict in which insulin proves to be a decisive weapon 12: Wall Street Gold - in an act of modern day alchemy, insulin makes stock market history 13: 'Don't You Want Cheap Insulin?' - What is it exactly that we want from science? And does the story of insulin have any lessons for us today? Bibliography Figures List and Acknowledgements for Images Acknowledgements End notes","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732599419223,"sku":"9780192855381","price":29.92,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780192855381.jpg?v=1719997590"},{"product_id":"the-rise-of-yeast-9780198749707","title":"The Rise of Yeast","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eYeast is humankind's favourite microbe, our partner in brewing, baking, and winemaking. Nicholas P. Money tells the story of this 10,000-year-long marriage, looking at how yeast served as a major factor in the development of civilization, celebrating its importance, and considering its future roles in molecular biology and genetic engineering.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eA highly entertaining read ... a fascinating and lucid historical study, rich with biological intrigue. * Timothy James, Current Biology *\u003cbr\u003eThe Rise of Yeast: How the sugar fungus shaped civilisation is an amazing story, about an amazing people-non-person relationship (and by an amazing writer): Surely, Moneys The Rise of Yeast is destined to be a classic and a thoroughly deserving award-winner! * Nigel Chaffey, Botany One, News and Views on Plant Biology and Ecology *\u003cbr\u003eThe Rise of Yeast is a neat little book that elegantly covers a lot of ground. * Leon Vlieger, Inquisitive Biologist *\u003cbr\u003eNicholas Money's effervescent tour is packed with delights, such as illustrations by Charles Tulasne, the Audubon of fungi, or the revelation that yeasts and humans share a common ancestor (and hundreds of genes). * Barabra Kiser, Nature *\u003cbr\u003eAn enjoyable and readable account. * Brewer \u0026amp; Distiller International *\u003cbr\u003eYeast rises our bread, ferments our beer, wine, and spirits, perfumes our fruit, nourishes our bodies, makes us bold in love, foments chaos, powers our cars, and unlocks the soul. We humans tend to think that we rule the earth, but the evidence on our behalf is scant. This fascinating book unlocks the mysteries of our world's true masters, which were here before we walked, will be here when we're gone, and, in the meantime, help make our time on the planet a lot more fun and infinitely more delicious. * Garrett Oliver, Brewmaster of the Brooklyn Brewery, Editor-in-Chief, The Oxford Companion to Beer *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eNOTES; BIBLIOGRAPHY; INDEX","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732777218391,"sku":"9780198749707","price":20.24,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198749707.jpg?v=1719998354"},{"product_id":"redesigning-life-9780198766834","title":"Redesigning Life","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSince the birth of civilisation, human beings have manipulated other life-forms. We have selectively bred plants and animals for thousands of years to maximise agricultural production and cater to our taste in pets. The observation of the creation of artificial animal and plant variants was a key stimulant for Charles Darwin''s theory of evolution. The ability to directly engineer the genomes of organisms first became possible in the 1970s, when the gene for human insulin was introduced into bacteria to produce this protein for diabetics. At the same time, mice were modified to produce human growth hormone, and grew huge as a result. But these were only our first tottering steps into the possibilities of genetic engineering.In the past few years, the pace of progress has accelerated enormously. We can now cut and paste genes using molecular scissors with astonishing ease, and the new technology of genome editing can be applied to practically any species of plants or animals. ''Mutation chain reaction'' can be used to alter the genes of a population of pests, such as flies; as the modified creatures breed, the mutation is spread through the population, so that within a few generations the organism is almost completely altered. At the same time, scientists are also beginning to synthesize new organisms from scratch.These new technologies hold much promise for improving lives. Genome editing has already been used clinically to treat AIDS patients, by genetically modifying their white blood cells to be resistant to HIV. In agriculture, genome editing could be used to engineer species with increased food output, and the ability to thrive in challenging climates. New bacterial forms may be used to generate energy. But these powerful new techniques also raise important ethical dilemmas and potential dangers, pressing issues that are already upon us given the speed of scientific developments. To what extent should parents be able to manipulate the genetics of their offspring  and would designer babies be limited to the rich? Can we effectively weigh up the risks from introducing synthetic lifeforms into complex ecosystems? In this extensively revised paperback edition, John Parrington explains the nature and possibilities of these new scientific developments, which could usher in a brave, new world. We must rapidly come to understand its implications if we are to direct its huge potential to the good of humanity and the planet.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003ea thorough and comprehensive account of the methodologies for altering life that have been or are being developed, and the directions that they may take in future. * Nature *\u003cbr\u003epainstakingly researched...the examples themselves are clear, concise and often arresting . . . an engaging and comprehensive introduction * LSE Business Review *\u003cbr\u003ea comprehensive history of the research and discoveries underlying genome editing, as well as a broad coverage of research in the present day. * Bionews *\u003cbr\u003eThere is a revolution going on in the life sciences, one that has already transformed scientific discovery and will soon change medicine. It could even see us altering the ecosystem in a precise, targeted way. This revolution has a name--CRISPR--and the key part of John Parrington's Redesigning Life is a good summary of the gene-editing technique that lies behind the acronym. * New Scientist *\u003cbr\u003eJohn Parrington's engaging and thoughtful book explains the science behind recent rapid advances in genetic engineering that mean it is increasingly possible to enact precise changes at a molecular level . . . Parrington's clear descriptions and diagrams combined with interesting snippets from the narrative and biography of scientific discovery make the science behind these developments readily accessible. * Socialist Review *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eList of plates List of figures Introduction: The Gene Revolution 1: Natural Born Mutants 2: Supersize My Mouse 3: Light as a Life Tool 4: The Gene Scissors 5: Next Year's Models 6: The Molecular Farm 7: New Gene Therapy 8: Regenerating Life 9: Life as a Machine 10: A Redesigned Planet? Glossary Endnotes Index of names Index of subjects","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732779839831,"sku":"9780198766834","price":11.69,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198766834.jpg?v=1719998365"},{"product_id":"biological-science-9780198783695","title":"Biological Science","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eA fresh approach to biology centred on a clear narrative, active learning, and confidence with quantitative concepts and scientific enquiry. Designed for flexible learning, it will give you a deeper understanding of the key concepts, and an appreciation of biology as a dynamic experimental science.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eLife and its Exploration: Foundational Principles Topic 1: Exploring the science of life Topic 2: The emergence of life on Earth Topic 3: Defining Life Topic 4: Evolutionary processes Topic 5: The diversity, organisation, and classification of life Quantitative Toolkits Quantitative Toolkit 1: Understanding data Quantitative Toolkit 2: Size and scale Quantitative Toolkit 3: Describing data Quantitative Toolkit 4: Ratio and proportion Quantitative Toolkit 5: Understanding samples Quantitative Toolkit 6: Designing experiments Quantitative Toolkit 7: Assessing patterns Quantitative Toolkit 8: Formulae and equations Quantitative Toolkit 9: Rates of change Module 1 LIFE AT THE MOLECULAR LEVEL 1: Building blocks: molecules and macromolecules 2: Energy: powering biochemical processes 3: Information: genes and genomes 4: Mendelian genetics 5: Reading the genome: gene expression and protein synthesis 6: Proteins and proteomes 7: Metabolism: energy capture and release from food 8: Molecular tools and techniques Module 2 LIFE AT THE CELLULAR LEVEL 9: Characteristics of prokaryotic and eukaryotic cells 10: Cell division in prokaryotes and eukaryotes 11: Microbial diversity 12: The growth, measurement, and visualisation of cells 13: Microbes in life: harnessing their power 14: Microbes as agents of infectious disease 15: Viruses Module 3 THE HUMAN ORGANISM: TISSUES, ORGANS, AND SYSTEMS 16: Physiology overview 17: Communication and control 1: introducing the nervous and endocrine systems 18: Communication and control 2: sensory systems 19: Communication and control 3: controlling organ systems 20: Muscle and movement 21: Cardiovascular system 22: Respiratory system 23: Exercise physiology 24: Renal system 25: Digestive system 26: Reproductive system 27: Immune system","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732782100823,"sku":"9780198783695","price":48.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198783695.jpg?v=1719998376"},{"product_id":"what-is-life-how-chemistry-becomes-biology-oxford-landmark-science-9780198784791","title":"What is Life How Chemistry Becomes Biology Oxford","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSeventy years ago, Erwin Schrödinger posed a profound question: ''What is life, and how did it emerge from non-life?'' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of ''systems chemistry'' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications.Oxford Landmark Science books are ''must-read'' classics of modern science writing which have crystallized big ideas, and shaped the way we think.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eIn this inspiring book, Pross provides an engaging account of the view that systems chemistry can bridge the hitherto unassailable abiogenic\/biogenic divide. In a carefully constructed, almost forensic, analysis, he confronts crucial issues, such as the conceptual gulf between the biochemist's chicken and egg problem...and the fundamental role of dynamic kinetic stability in the process of life. * Ben Mepham, The Biologist *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePrologue 1: Living things are so very strange 2: Historic quest for a theory of life 3: Understanding 'understanding' 4: Stability and instability 5: The knotty origin of life problem 6: Biology's crisis of identity 7: Biology is chemistry 8: What is Life? References and Notes Index","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732782821719,"sku":"9780198784791","price":11.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198784791.jpg?v=1719998377"},{"product_id":"molecular-biology-9780198788652","title":"Molecular Biology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe biological world operates on a multitude of scales - from molecules to cells to tissues to organisms to ecosystems. Throughout all these levels runs a common thread: the communication and onward passage of information - from cell to cell, from organism to organism and, ultimately, from generation to generation. But how does this information - no more than a static repository of data - come alive to govern the processes that constitute life?The answer lies in the concerted action of molecular components which cooperate through a series of carefully-regulated processes to bring the information in our genome to life. These components and processes lie at the heart of one of the most fascinating subjects to engage the minds of scientists today: molecular biology.Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to the teaching of molecular biology. It is an approach that reflects the challenge of teaching a subject that is in many ways unrecognizable from the molecular biology of the 20th century - a discipline in which our understanding has advanced immeasurably, but about which many questions remain to be answered.It is written with several guiding themes in mind:- A focus on key principles provides a robust conceptual framework on which students can build a solid understanding of the discipline;- An emphasis on the commonalities that exist between the three kingdoms of life, and the discussion of differences between the three kingdoms where such differences offer instructive insights into molecular processes and components, gives students an accurate depiction of our current understanding of the conserved nature of molecular biology, and the differences that underpin biological diversity;- An integrated approach demonstrates how certain molecular phenomena have diverse impacts on genome function by presenting them as themes that recur throughout the book, rather than as artificially separated topicsAt heart, molecular biology is an experimental science, and a central element to the understanding of molecular biology is an appreciation of the approaches taken to yield the information from which concepts and principles are deduced. Yet there is also the challenge of introducing the experimental evidence in a way that students can readily comprehend.Molecular Biology responds to this challenge with Experimental Approach panels, which branch off from the text in a clearly-signposted way. These panels describe pieces of research that have been undertaken, and which have been particularly valuable in elucidating different aspects of molecular biology. Each panel is carefully cross-referenced to the discussion of key molecular biology tools and techniques, which are presented in a dedicated chapter at the end of the book.Beyond this, Molecular Biology further enriches the learning experience with full-colour, custom-drawn artwork; end-of-chapter questions and summaries; relevant suggested further readings grouped by topic; and an extensive glossary of key terms.Among the students being taught today are the molecular biologists of tomorrow; these individuals will be in a position to ask fascinating questions about fields whose complexity and sophistication become more apparent with each year that passes. Molecular Biology: Principles of Genome Function is the perfect introduction to this challenging, dynamic, but ultimately fascinating discipline.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eThis is a comprehensive molecular biology textbook that emphasizes biochemical principles and molecular interactions... I believe that overall, it's the best text available for my students. * Donna E Crone, Rensselaer Polytechnic Institute *\u003cbr\u003eConveys in-depth material in an easily digestible manner. Makes clear connections between different topics to improve understanding of key concepts. * Scott Bailey, Johns Hopkins University *\u003cbr\u003eThis book would be excellent for a 300- or 400- level course and provides a nice entrée into using primary literature and experimental results in the lecture. * Harold Olivey, Indiana University Northwest *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eGenomes and the flow of biological informationBiological moleculesThe chemical basis of lifeChromosome structure and functionThe cell cycleDNA replicationChromosome segregationTranscriptionRegulation of transcriptionRNA processingTranslationRegulation of translationRegulatory RNAsProtein modification and targetingCellular responses to DNA damageRepair of DNA double-strand breaks and homologous recombinationMobile DNAGenomics and genetic variationTools and techniques in molecular biology","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732784558423,"sku":"9780198788652","price":63.64,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198788652.jpg?v=1719998387"},{"product_id":"cell-signalling-9780198859581","title":"Cell Signalling","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten primarily for students embarking on an undergraduate bioscience degree, this primer provides a clear introduction to the main aspects of cell signalling in biological systems, demystifying the subject for those new to the field. The primer provides an overview of cell signalling and highlights its importance in all organisms, before going on to describe the main components of cell signalling and examples of signal transduction pathways. The discussion then progresses on to key physiological conditions in which cell signalling has an instrumental role: cancer, apoptosis and diabetes. After getting to grips with the fundamentals of the subject, Cell Signalling opens a discussion on the future of the discipline, including how manipulation of cell signalling pathways is seen as the biggest target for the pharmaceutical industry, and how crop diseases, plant survival during stress, and post-harvest storage are all influenced by cell signalling pathways.Cell Signalling is supported b\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Introduction to cell signalling 2: Signals and their perception 3: Modifications to proteins that control cell signalling 4: Intracellular signals 5: Cell signalling disorders; cancers and apoptosis 6: Stress responses and the changing cell environment 7: Future challenges and perspectives in cell signalling","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732816965975,"sku":"9780198859581","price":24.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198859581.jpg?v=1719998523"},{"product_id":"protein-structure-and-function-9780199556847","title":"Protein Structure and Function","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eHow does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein?Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure int\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eA really good book provides a wealth of information in a manner that the reader remembers what he\/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner. * Tom Bruice, University of California, Santa Barbara *\u003cbr\u003eThis treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences. * James Spudich, Stanford University School of Medicine *\u003cbr\u003eIt is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one. * Roman Laskowski, European Bioinformatics Institute *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. From Sequence to Structure ; 2. From Structure to Function ; 3. Control of Protein Function ; 4. From Sequence to Function: Case Studies in Structural and Functional Genomics ; 5. Structure Determination","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732864184663,"sku":"9780199556847","price":66.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199556847.jpg?v=1719998722"},{"product_id":"introduction-to-glycobiology-9780199569113","title":"Introduction to Glycobiology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIntroduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition This book is an absolute must for all lecturers and students alike of glycobiology ... Wholeheartedly recommended. * Microbiology Today, November 2006 *\u003cbr\u003eIt covers the breadth of glycobiology very well and provides sufficient depth to provide a platform for further research. * Dr Gavin M. Brown, Lancaster University *\u003cbr\u003eOthers are not written as clearly or concisely as Taylor and Drickamer. * Prof Y.C. Lee, John Hopkins University *\u003cbr\u003eI prefer this book highly above the other text books available. * Prof Dr J.P. Kamerling, Utrecht University *\u003cbr\u003eDr Taylor and Professor Drickamer should be congratulated on writing a textbook that presents the enormous subject of glycobiology with energy and enthusiasm and doing so in a manner that should be accessible to their target audience. * Biochemist e-volution, April 2006 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePART 1: STRUCTURES AND BIOSYNTHESIS OF GLYCANS; PART 2: GLYCANS IN BIOLOGY","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732866445655,"sku":"9780199569113","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"molecular-biology-of-rna-9780199671397","title":"Molecular Biology of RNA","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe versatile RNA molecule, along with its many forms and functions, is elegantly captured in this succinct undergraduate text. Molecular Biology of RNA describes how RNA is not only an intrinsic part of the 'central dogma' of molecular biology, but also plays a part in processes as diverse as the regulation of gene expression and catalysis.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition Highly detailed, and well illustrated, ^Molecular Biology of RNA represents the first text to address exclusively the role of RNA in biological systems. * Kevin Coward in Journal of Biological Education, 2012 *\u003cbr\u003eThis comprehensive textbook is pitched at just the right level and explains the concepts in sufficient detail to make them come to life. * Ilan Davis in Development, 2011 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Introduction to Molecular Biology of RNA ; 2. RNA can form versatile structures ; 3. Catalytic RNAs ; 4. The RNA-binding proteins ; 5. Pre-mRNA splicing by the spliceosome ; 6. Regulated alternative splicing ; 7. Pre-mRNA splicing defects in development and disease ; 8. Co-transcriptional pre-mRNA processing ; 9. Nucleocytoplasmic traffic of messenger RNA ; 10. Messenger RNA localization ; 11. Translation of messenger RNA ; 12. Stability and degradation of mRNA ; 13. RNA editing ; 14. The biogenesis and nucleocytoplasmic traffic of non-coding RNAs ; 15. The 'macro' RNAs: long non-coding RNAs and epigenetics ; 16. The short non-coding RNAs and gene silencing ; 17. RNA biology: future perspectives","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732880404823,"sku":"9780199671397","price":60.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199671397.jpg?v=1719998792"},{"product_id":"methods-in-molecular-biophysics-structure-dynamics-function-for-biology-and-medicine-9781107056374","title":"Methods in Molecular Biophysics Structure","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eCurrent techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview of first edition: '… a valuable contribution to the field. … There is nothing quite like it at the moment.' Sir Tom Blundell FRS, University of Cambridge\u003cbr\u003eReview of first edition: … one of the most comprehensive and highly relevant texts on biophysics that I have encountered in the last 10 years, clearly written and up-to-date … a must-have for biophysicists working in all lines of research …' Nikolaus Grigorieff, Brandeis University, Massachusetts\u003cbr\u003eReview of first edition: '… a wonderful up-to-date treatise on the many and diverse methods used … in the fields of molecular biophysics, physical biochemistry, molecular biology, biological physics and the new and emerging field of quantum nanobiology.' Karl J. Jalkanen, Quantum Protein Centre, Technological University of Denmark\u003cbr\u003eReview of first edition: '… a valuable resource for novice and seasoned biophysicists alike.' Dan Minor, California Institute for Quantitative Biomedical Research, University of California\u003cbr\u003eReview of first edition: '… the book I consult first when faced with an unfamiliar experimental technique. Both classic analytical techniques and the latest single-molecule methods appear in this single comprehensive reference.' Philip Nelson, University of Pennsylvania and author of Biological Physics\u003cbr\u003eReview of first edition: '… valuable both for students and research scientists.' Michael G. Rossmann, Hanley Professor of Biological Sciences, Purdue University\u003cbr\u003eReview of first edition: 'A great achievement … awaits the student who reads this book … an excellent reference for the seasoned practitioner of biophysical chemistry.' Milton H. Werner, The Rockefeller University\u003cbr\u003eReview of first edition: 'This well written, thorough, and elegantly illustrated book provides the connections between molecular biophysics and biology that every aspiring young biologist needs.' Stephen H. White, University of California at Irvine\u003cbr\u003eReview of first edition: '… I enthusiastically recommend Methods in Molecular Biophysics to anyone who wishes to know more about the techniques by which the properties of biological macromolecules are determined.' David Worcester, University of Missouri\u003cbr\u003eReview of first edition: 'A book that teaches the methods well, creates the intellectual framework of our understanding, and can guide the field. Earlier efforts by Cohn and Edsall, Tanford, Edsall and Wyman, and Cantor and Schimmel have served this important purpose in the past, but the advance of time and technology has diluted the force of these classic works in contemporary Biophysics, both in the teaching and the practices of the field. How welcome, then, a clearly written, thoughtful and modern text that will serve well, both in formal courses and as a reference. The authors have built each method from its fundamental premises and principles, have successfully covered an impressive span of topics, and will be rewarded by attention from an audience that hungers for the next defining text in Molecular Biophysics.' D. M. Engelman, Yale University, New Haven\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface to the first edition; Preface to the second edition; Introduction; Part I. Biological Macromolecules and Physical Tools: 1. Macromolecules in their environment; 2. Macromolecules as physical particles; 3. Understanding macromolecular structures; Part II. Mass Spectrometry: 4. Mass and charge; 5. Structure function studies; Part III. Thermodynamics: 6. Thermodynamic stability and interactions; 7. Differential scanning calorimetry; 8. Isothermal titration calorimetry; 9. Surface plasmon resonance and interferometry-based biosensors; Part IV. Hydrodynamics: 10. Biological macromolecules as hydrodynamic particles; 11. Analytical ultracentrifugation; 12. Fluorescence depolarization; 13. Dynamic light scattering and fluorescence correlation spectroscopy; Part V. Optical Spectroscopy: 14. Visible and IR absorption spectroscopy; 15. Two-dimensional IR spectroscopy; 16. Raman scattering spectroscopy; 17. Optical activity and circular dichroïsm; Part VI. Optical Microscopy: 18. Light microscopy; 19. Single molecule manipulation and atomic force microscopy; 20. Fluorescence microscopy; 21. Single-molecule detection; 22. Single-molecule manipulation; Part VII. X-Ray and Neutron Diffraction: 23. The macromolecule as a radiation scattering particle; 24. Small-angle scattering and reflectometry; 25. X-ray and neutron macromolecular crystallography; Part VIII. Electron Diffraction: 26. Electron microscopy; 27. Three-dimensional reconstruction from two-dimensional images; Part IX. Molecular Dynamics: 28. Energy and time calculations; 29. Neutron spectroscopy; Part X. Nuclear Magnetic Resonance: 30. Distances and angles from frequencies; 31. Experimental techniques; 32. Structure and dynamics studies; Part XI. Medical Imaging: 33. Radiology and positron emission tomography; 34. Ultrasound imaging; 35. Magnetic resonance imaging; References; Index of eminent scientists; Subject index.","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":48738246787415,"sku":"9781107056374","price":64.35,"currency_code":"GBP","in_stock":true}]},{"product_id":"understanding-development-9781108799232","title":"Understanding Development","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eDevelopmental biology is seemingly well understood, with development widely accepted as being a series of programmed changes through which an egg turns into an adult organism, or a seed matures into a plant. However, the picture is much more complex than that: is it all genetically controlled or does environment have an influence? Is the final adult stage the target of development and everything else just a build-up to that point? Are developmental strategies the same in plants as in animals? How do we consider development in single-celled organisms? In this concise, engaging volume, Alessandro Minelli, a leading developmental biologist, addresses these key questions. Using familiar examples and easy-to-follow arguments, he offers fresh alternatives to a number of preconceptions and stereotypes, awakening the reader to the disparity of developmental phenomena across all main branches of the tree of life.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e'Developmental biology has been described as the process by which a fertilized egg is transformed into a multicellular organism. But is it? In this thoughtful and erudite book, Alessandro Minelli forces us to step back and reconsider the subject. Using an astonishing range of examples, from pythons to lichens and from sponges to ciliates, Minelli challenges a series of generalizations and preconceptions. We see how development is not only the process of building adults, why development does not have end-points, how development need not start with a fertilized egg, why we must be careful with the concept of developmental genes, and much more. After reading this book, you might not think about developmental biology in the same way again.' Peter Holland, University of Oxford, UK\u003cbr\u003e'This is the finest book on the principles underpinning biological development that I have read in a long time. It is succinct, thoughtful and full of examples, offering wise reflection on the diversity of developmental phenomena across the whole tree of life. Understanding Development is especially notable for its organization into 48 sections comprising 8 chapters. Each section subtitle states a key lesson to be learned through brief historical and theoretical expositions, well-chosen examples, and stories of odd-ball and familiar life forms. Every lesson overturns some conventional wisdom or common knowledge that cannot stand up to the wondrous diversity of life on Earth. Minelli's broad, deep knowledge of the field is expressed with an engaging contrarian spirit that serves his larger goal: to prompt a reassessment of the state of contemporary understanding of development in a way accessible to novice and expert alike.' James Griesemer, University of California, Davis, USA\u003cbr\u003e'Developmental biology is a highly dynamic area of the life sciences, and it also lacks a unifying theoretical framework and must rely on general principles derived from a small number of well-studied model organisms. In Understanding Development, Minelli channels an encyclopaedic knowledge of biological diversity to convincingly show the need for a more expansive concept of development that can embrace the variability and complexity of life. Minelli surveys the interplay of generalizations and exceptions that arise in the study of development, tracing out important open conceptual challenges facing researchers today. Engagingly written and always insightful, this book is highly recommended to biologists, philosophers of biology, and historians interested in grappling with a fundamental and active problem area in the contemporary landscape of biological thought.' James DiFrisco, KU Leuven, Belgium\u003cbr\u003e'The text assumes a basic acquaintance with evolution, genetics, and embryology and is at once well written, entertaining, and loaded with fascinating examples of organisms that defy expectations … Highly recommended.' J. L. Hunt, Choice Magazine\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Defining development, If possible; 2. Cells and development; 3. Development as the history of the individual; 4. Revisiting the embryo; 5. Developmental sequences: sustainability vs adaptation; 6. Genes and development; 7. Emerging form; 8. The ecology of development; Concluding remarks.","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":48738333000023,"sku":"9781108799232","price":13.94,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781108799232.jpg?v=1723811938"},{"product_id":"blood-science-9781119864110","title":"Blood Science","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eAcknowledgements\u003c\/p\u003e \u003cp\u003eList of Abbreviations\u003c\/p\u003e \u003cp\u003eAbout the Companion Website\u003c\/p\u003e \u003cp\u003e1. Introduction to Blood Science\u003c\/p\u003e \u003cp\u003e2. Analytical Techniques in Blood Science\u003c\/p\u003e \u003cp\u003e3. The Physiology of the Red Blood Cell\u003c\/p\u003e \u003cp\u003e4. The Pathology of the Red Blood Cell\u003c\/p\u003e \u003cp\u003e5. White Blood Cells in Health and Disease\u003c\/p\u003e \u003cp\u003e6. White Blood Cell Malignancy\u003c\/p\u003e \u003cp\u003e7. The Physiology and Pathology of Haemostasis\u003c\/p\u003e \u003cp\u003e8. The Diagnosis and Management of Disorders of Haemostasis\u003c\/p\u003e \u003cp\u003e9. Immunopathology\u003c\/p\u003e \u003cp\u003e10. Immunogenetics and Histocompatibility\u003c\/p\u003e \u003cp\u003e11. Blood Transfusion\u003c\/p\u003e \u003cp\u003e12. Waste products, electrolytes, and renal disease\u003c\/p\u003e \u003cp\u003e13. Hydrogen ions, pH, and acid-base disorders\u003c\/p\u003e \u003cp\u003e14. Glucose, lipids, and atherosclerosis\u003c\/p\u003e \u003cp\u003e15. Calcium, phosphate, magnesium, and bone disease\u003c\/p\u003e \u003cp\u003e16. Nutrients and Gastrointestinal Disorders\u003c\/p\u003e \u003cp\u003e17. Liver function tests and plasma proteins\u003c\/p\u003e \u003cp\u003e18. Endocrinology\u003c\/p\u003e \u003cp\u003e19. Cancer and tumour markers\u003c\/p\u003e \u003cp\u003e20. Inherited Metabolic Disorders\u003c\/p\u003e \u003cp\u003e21. Drugs and Poisons\u003c\/p\u003e \u003cp\u003e22. Case Reports in Blood Science\u003c\/p\u003e \u003cp\u003eFurther Reading\u003c\/p\u003e \u003cp\u003eAppendix 1: Reference Ranges\u003c\/p\u003e \u003cp\u003eGlossary\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48738376712535,"sku":"9781119864110","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"beckers-world-of-the-cell-global-edition-9781292426525","title":"Beckers World of the Cell Global Edition","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eJEFFHARDIN received his Ph.D. in Biophysics from the University ofCaliforniaBerkeley. He is the Raymond E. Keller Professor and Chair of theDepartment of Integrative Biology at the University of WisconsinMadison, wherehe has been since 1991. For 18 years he was Faculty Director of the BiologyCore Curriculum, a four-semester honors biology sequence for undergraduates atWisconsin known for its teaching innovations. Jeff 's research focuses on howcells migrate and adhere to one another during early embryonic development.Jeff 's teaching is enhanced by his extensive use of digital microscopy and hisweb-based teaching materials, which are used on many campuses in the UnitedStates and in other countries. Jeff was a founding member of the UW TeachingAcademy, and has received several teaching awards, including a Lily TeachingFellowship, a National Science Foundation Young Investigator Award, and aChancellor's Distinguished Teaching Award.\u003c\/p\u003e \u003cp\u003eJAMES P.LODOLCE earned his Ph.D. in Immunolog\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e1. A Preview of Cell Biology\u003cbr\u003e2. The Chemistry of the Cell\u003cbr\u003e3. The Macromolecules of the Cell\u003cbr\u003e4. Cells and Organelles\u003cbr\u003e5. Bioenergetics: The Flow of Energy in the Cell\u003cbr\u003e6. Enzymes: The Catalysts of Life\u003cbr\u003e7. Membranes: Their Structure, Function, and Chemistry\u003cbr\u003e8. Transport Across Membranes: Overcoming the Permeability Barrier\u003cbr\u003e9. Chemotrophic Energy Metabolism: Glycolysis and Fermentation\u003cbr\u003e10. Chemotrophic Energy Metabolism: Aerobic Respiration\u003cbr\u003e11. Phototrophic Energy Metabolism: Photosynthesis\u003cbr\u003e12. The Endomembrane System and Protein Sorting \u003cbr\u003e13. Cytoskeletal Systems\u003cbr\u003e14. Cellular Movement: Motility and Contractility\u003cbr\u003e15. Beyond the Cell: Cell Adhesions, Cell Junctions, and Extracellular Structures\u003cbr\u003e16. The Structural Basis of Cellular Information: DNA, Chromosomes, and theNucleus\u003cbr\u003e17. DNA Replication, Repair, and Recombination\u003cbr\u003e18. Gene Expression: I. Transcription\u003cbr\u003e19. Gene Expression: II. The Genetic Code and Protein Synthesis\u003cbr\u003e20. The Regulation of Gene Expression\u003cbr\u003e21. Molecular Biology Techniques for Cell Biology\u003cbr\u003e22. Signal Transduction Mechanisms: I. Electrical and Synaptic Signaling inNeurons\u003cbr\u003e23. Signal Transduction Mechanisms: II. Messengers and Receptors\u003cbr\u003e24. The Cell Cycle and Mitosis\u003cbr\u003e25. Sexual Reproduction, Meiosis, and Genetic Recombination\u003cbr\u003e26. Cancer Cells\u003cbr\u003eAppendix: Visualizing Cells and Molecules  \u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e","brand":"Pearson Education Limited","offers":[{"title":"Default Title","offer_id":48738548646231,"sku":"9781292426525","price":61.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781292426525.jpg?v=1723812132"},{"product_id":"genomics-in-the-cloud-9781491975190","title":"Genomics in the Cloud","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eData in the genomics field is booming. With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra.","brand":"O'Reilly Media","offers":[{"title":"Default Title","offer_id":48739718365527,"sku":"9781491975190","price":53.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781491975190.jpg?v=1720052984"},{"product_id":"prostate-cancer-9781621821649","title":"Prostate Cancer","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Cold Spring Harbor Laboratory Press,U.S.","offers":[{"title":"Default Title","offer_id":48740662214999,"sku":"9781621821649","price":71.4,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781621821649.jpg?v=1723812317"},{"product_id":"scale-the-universal-laws-of-life-and-death-in-organisms-cities-and-companies-9781780225593","title":"Scale: The Universal Laws of Life and Death in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eGeoffrey West's research centres on a quest to find unifying principles and patterns connecting everything, from cells and ecosystems to cities, social networks and businesses.\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ci\u003eWhy do organisms and ecosystems scale with size in a remarkably universal and systematic fashion?\u003c\/i\u003e\u003cbr\u003e\u003cbr\u003e\u003ci\u003eIs there a maximum size of cities? Of animals and plants? What about companies?\u003c\/i\u003e\u003cbr\u003e\u003cbr\u003e\u003ci\u003eCan scale show us how to create a more sustainable future?\u003c\/i\u003e\u003cbr\u003e\u003cbr\u003eBy applying the rigour of physics to questions of biology, visionary physicist Geoffrey West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. This speaks to everything from how long we can expect to live to how many hours of sleep we need. He then made the even bolder move of exploring his work's applicability to cities and to the business world. These investigations have led to powerful insights about the elemental natural laws that bind us together in profound ways, and how all complex systems are dancing to the same simple tune, however diverse and unrelated they may seem.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e'\u003cb\u003eThe sort of big-ideas book that comes along only every few years\u003c\/b\u003e . . . This is a book full of \u003cb\u003ethrilling\u003c\/b\u003e ideas' * Sunday Times *\u003cbr\u003e'\u003cb\u003eMagisterial\u003c\/b\u003e . . . you reach the end of this \u003cb\u003eprofound\u003c\/b\u003e, revealing book rewarded. West shows how scientific method \u003cb\u003ehelps to peel back the hidden reality of our world\u003c\/b\u003e. The concepts of physics dominated the last century. It is the concepts of biology - of networks, evolution and feedback dynamics - that are going to dominate the next' -- Matthew Syed * The Times *\u003cbr\u003e'\u003cb\u003eQuite dazzling\u003c\/b\u003e . . . The book proceeds by introducing one mathematical concept in each chapter (power laws, fractals and so on), and explaining it vividly through numerous examples drawn from biology, history, urban planning, and many other fields . . . \u003cb\u003ewritten with great joy and a disarming humility\u003c\/b\u003e' -- Steven Poole * The Spectator *\u003cbr\u003e'An \u003cb\u003eabsolutely riveting\u003c\/b\u003e read. Like the best detective story, West lays out the amazing challenge of understanding why animals, cities and companies all scale so uniformly and then skilfully lets us into the secrets that his detective work has uncovered. This book captures the spirit of science in the twenty-first century, revealing the deep connections not just across physics and biology but society and life. The book is \u003cb\u003ea perfect balance\u003c\/b\u003e between the big scientific story and West's own personal narrative. We accompany the author on his quest to face up to his own mortality while at the same time being exposed to the theoretical discoveries that West has pioneered in his \u003cb\u003egroundbreaking\u003c\/b\u003e work' -- Marcus du Sautoy, Simonyi Professor for the Public Understanding of Science at Oxford University and author of \u003ci\u003eThe Great Unknown \u003c\/i\u003e\u003cbr\u003e'This is an\u003cb\u003e important and original\u003c\/b\u003e book, of immense scope. Geoffrey West is a polymath, whose insights range over physics, biology and the social sciences. He shows that the sizes, shapes and lifetimes of living things - despite their amazing diversity - display surprising correlations and patterns, and that these follow from basic physical principles. He then discovers, more surprisingly, the emergence of similar 'scaling laws' in human societies - in our cities, companies and social networks. \u003cb\u003eThis fascinating book deserves a very wide readership\u003c\/b\u003e' -- Lord Martin Rees, Astronomer Royal\u003cbr\u003e'Scaling is the most important yet most hidden and rarely discussed attribute -- without understanding it one cannot possibly understand the world. \u003cb\u003eThis book will expand your thinking from three dimensions to four\u003c\/b\u003e. Get two copies, just in case you lose one' -- Nassim Nicholas Taleb\u003cbr\u003e'\u003cb\u003eI can think of no more exciting thinker in the world today than Geoffrey West\u003c\/b\u003e. By bringing a physicist's razor-sharp mind to wonderfully surprising questions - \"Why Aren't There Mammals the Size of Tiny Ants?\" or \"Are Cities and Companies Just Very Large Organisms?\" - West forces us to see everything anew, from our own bodies to the mega-cities our species increasingly chooses to inhabit. \u003cb\u003e\u003ci\u003eScale\u003c\/i\u003e is a firework display of popular science\u003c\/b\u003e' -- Niall Ferguson\u003cbr\u003e'Trees, brains, hallucinogenics and even imaginary monsters are considered in this \u003cb\u003ejoyous, mind-boggling\u003c\/b\u003e study of scientific methods' * Telegraph, Top 50 Best Books of 2017 *\u003cbr\u003e'An \u003cb\u003eenchanting intellectual odyssey\u003c\/b\u003e . . . also a satisfying personal and professional memoir of a distinguished scientist whose life's work came to be preoccupied with finding ways to break down traditional boundaries between disciplines to solve the long-term global challenges of sustainability . . . Mr West manages to deliver a lot of theory and history accessibly and entertainingly . . . \u003cb\u003eProvocative and fascinating\u003c\/b\u003e' * New York Times *\u003cbr\u003e'It's rare in the history of science that someone has \u003cb\u003ea big, bold, beautiful, stunningly simple new\u003c\/b\u003e idea that also turns out to be right. Geoffrey West had one. And \u003ci\u003eScale\u003c\/i\u003e is its story' -- Steven Strogatz, Professor of Mathematics, Cornell University and author of \u003ci\u003eThe Joy of X \u003c\/i\u003e\u003cbr\u003e'\u003cb\u003eGeoffrey West's \u003ci\u003eScale \u003c\/i\u003eis a revelation\u003c\/b\u003e. Based on his path-breaking theory and research on super-linear scaling, it provides powerful new insights into the basic scientific laws that power our modern society and economy, its start-up companies, large corporations and cities. \u003cb\u003eThe book is a must-read\u003c\/b\u003e for CEOs, technologists, mayors, urban leaders and anyone who wants to understand the simple laws that shape the complex, self-organizing world in which we live' -- Richard Florida, author of THE RISE OF THE CREATIVE CLASS and a senior editor at THE ATLANTIC\u003cbr\u003e'\u003ci\u003eScale\u003c\/i\u003e is \u003cb\u003efilled with brilliant insights\u003c\/b\u003e. West \u003cb\u003eilluminates the laws of nature\u003c\/b\u003e underlying everything from tiny organisms and humans to cities and companies, and provides a quantitative framework for decoding the deep complexity of our interconnected world. If you want to know why companies fail, how cities persist and what is needed to sustain our civilization in this era of rapid innovation, \u003cb\u003eread this amazing book\u003c\/b\u003e' -- Marc Benioff, founder and CEO of Salesforce\u003cbr\u003e'If there were a Nobel Prize for transdisciplinary science Geoffrey West would have won it for the work covered in \u003ci\u003eScale\u003c\/i\u003e. T\u003cb\u003ehis is a book of great originality and deep importance\u003c\/b\u003e, containing startling insights about topics as seemingly unrelated as aging and death, sleep, metabolism, cities, energy use, creativity, corporations, and even the sustainability of our existence.  \u003cb\u003eIf you are curious about how the world really works, you must read this book\u003c\/b\u003e' -- Bill Miller, LMM Investments\u003cbr\u003e'This \u003cb\u003espectacular\u003c\/b\u003e book on how logarithmic scaling governs everything is packed with news - from the self-similar dynamics of cells and ecosystems to exactly why companies always die and cities don't. \u003cb\u003eI dog-eared and marked up damn near every page\u003c\/b\u003e' -- Stewart Brand, creator of the WHOLE EARTH CATOLOG\u003cbr\u003e'When Geoffrey West, a brilliant theoretical physicist, turned his lens to the study of life spans, biological systems or cities he stumbled onto a game-changing universal insight about growth and sustainability.  \u003cb\u003e\u003ci\u003eScale\u003c\/i\u003e is dazzling and provocative\u003c\/b\u003e and West proves himself to be a compelling and entertaining writer - \u003cb\u003ethis is a book we will be talking about for a long time\u003c\/b\u003e' -- Abraham Verghese, author of CUTTING FOR STONE\u003cbr\u003e\u003cp\u003eThis book is breathtaking in its scope and vision! It represents the culmination of exciting theoretical work addressing critical questions in life. Written by a clever physicist and one of the most influential thinkers of the time, Geoffrey West, this volume elaborates on the author's intriguing discovery that the growth, organisation and dynamics of humans, animals and plants scale with their size.  .....It is really an enjoyable read\u003cbr\u003ethat takes readers on a journey of fresh insights and illuminating perspectives.\u003c\/p\u003e -- Walid El-Sharoud * SCIENCE PROGRESS *\u003cbr\u003eIn this \"grand unified theory of sustainability\", physicist Geoffrey West explores underlying laws that link society and nature, called scaling theory. Insights (into city size and walking speed, for instance) abound -- Mary Craig * NATURE *","brand":"Orion Publishing Co","offers":[{"title":"Default Title","offer_id":48740986388823,"sku":"9781780225593","price":10.44,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781780225593.jpg?v=1720056221"},{"product_id":"synthetic-biology-a-primer-revised-edition-9781783268795","title":"Synthetic Biology - A Primer (Revised Edition)","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSynthetic Biology — A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made.The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch exploring the fundamental basis of living systems.Examples of cutting-edge applications designed using synthetic biology principles are presented, including: The book also describes the Internationally Genetically Engineered Machine (iGEM) competition, which brings together students and young researchers from around the world to carry out summer projects in synthetic biology. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences into synthetic biology research.Final year undergraduates, postgraduates and established researchers interested in learning about the interdisciplinary field of synthetic biology will benefit from this up-to-date primer on synthetic biology.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eList of Contributors; Preface; Introduction to Biology; Basic Concepts in Engineering Biology; Foundational Technologies; Minimal Cells and Synthetic Life; Parts, Devices and Systems; Modelling Synthetic Biology Systems; Applications of Designed Biological Systems; iGEM; The Societal Impact of Synthetic Biology; Appendices:\tProforma of Common Laboratory Techniques; Glossary; Index;","brand":"Imperial College Press","offers":[{"title":"Default Title","offer_id":48741166481751,"sku":"9781783268795","price":28.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781783268795.jpg?v=1720056780"},{"product_id":"natural-product-biosynthesis-chemical-logic-and-enzymatic-machinery-9781839165641","title":"Natural Product Biosynthesis: Chemical Logic and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eAuthored by leading experts in the enzymology of natural product biosynthesis, this completely revised and updated edition provides a description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Although some 500 000 – 600 000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism.    This second edition integrates many new findings into the sets of principles of the first edition that parsed categories of natural product chemistries into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. New chapters include evaluation of a core set of thermodynamically activated but kinetically stable metabolites that power both primary and secondary metabolic pathways. Also, after decades of uncertainty about the existence of various pericyclase classes, a series of genome mining, heterologous expression, and enzymatic activity characterization have validated a plethora of pericyclases over the past decade. The several types of pericyclases are involved in biosynthetic complexity generation of almost every major category of natural products.    This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, pharmacognocists and chemical ecologists, and bioengineers and synthetic biologists.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eMajor Classes of Natural Product Scaffolds and Enzymatic Biosynthetic Machinery; The Chemical Logic for Major Reaction Types; Polyketide Natural Products; Peptide Natural Products I: RiPPs; Peptide Natural Products II: Nonribosomal Peptides; Isoprenoids\/Terpenes; Alkaloids I; Purine- and Pyrimidine-derived Natural Products; Phenylpropanoid Natural Product Biosynthesis; Alkaloids II: Indole Terpenes; Natural Product Oligosaccharides and Glycosides; Oxygenases, Thwarted Oxygenases, and Oxygen-dependent Halogenases; S-Adenosylmethionine; Pericyclases in Natural Product Biosynthesis; Natural Products Isolation and Characterization: Gene-independent Approaches; Natural Products in the Post Genomic Era","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741984698711,"sku":"9781839165641","price":94.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781839165641.jpg?v=1720059562"},{"product_id":"heart-of-the-matter-key-concepts-in-cardiovascular-science-9783030242183","title":"Heart of the Matter: Key concepts in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eThis textbook introduces readers to the scientific basics of cardiovascular medicine and biology. 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Focused on the genes and signaling pathways involved in the most common tumors, \u003ci\u003ePrinciples of Cancer Genetics\u003c\/i\u003e is a highly readable account that will be of interest to anyone who would like to attain a basic understanding of cancer biology. Students who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff will find this book to be a useful starting point toward mastery of this complex but fascinating topic. This updated edition delves into the critical interactions between growing tumors and the immune system, and introduces the concepts of T cell activation, immunoediting and immune evasion. Novel strategies for cancer diagnosis and prognosis, including new roles for next-generation sequencing and liquid biopsies, as well as established and emerging therapeutic modalities are now described in detail.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eFor laypersons, students and researchers in other fields with a general interest in cancer, this book provides an accessible overview, enriched with many easy-to-understand illustrations. For advanced students considering future study in the field of oncology and cancer research, this concise book is a useful guide to the basic principles that underlie our understanding of cancer.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003esee attachment\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743064437079,"sku":"9783030993894","price":56.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783030993894.jpg?v=1720063953"},{"product_id":"bioanalytics-analytical-methods-and-concepts-in-biochemistry-and-molecular-biology-9783527339198","title":"Bioanalytics: Analytical Methods and Concepts in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eAnalytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids.\u003cbr\u003e \u003cbr\u003e The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. \u003cbr\u003e \u003cbr\u003e The following techniques are covered in detail:\u003cbr\u003e \u003cbr\u003e - Purification and determination of proteins\u003cbr\u003e - Measuring enzymatic activity\u003cbr\u003e - Microcalorimetry\u003cbr\u003e - Immunoassays, affinity chromatography and other immunological methods\u003cbr\u003e - Cross-linking, cleavage, and chemical modification of proteins\u003cbr\u003e - Light microscopy, electron microscopy and atomic force microscopy\u003cbr\u003e - Chromatographic and electrophoretic techniques\u003cbr\u003e - Protein sequence and composition analysis\u003cbr\u003e - Mass spectrometry methods\u003cbr\u003e - Measuring protein-protein interactions\u003cbr\u003e - Biosensors\u003cbr\u003e - NMR and EPR of biomolecules\u003cbr\u003e - Electron microscopy and X-ray structure analysis\u003cbr\u003e - Carbohydrate and lipid analysis\u003cbr\u003e - Analysis of posttranslational modifications\u003cbr\u003e - Isolation and determination of nucleic acids\u003cbr\u003e - DNA hybridization techniques\u003cbr\u003e - Polymerase chain reaction techniques\u003cbr\u003e - Protein sequence and composition analysis\u003cbr\u003e - DNA sequence and epigenetic modification analysis\u003cbr\u003e - Analysis of protein-nucleic acid interactions\u003cbr\u003e - Analysis of sequence data\u003cbr\u003e - Proteomics, metabolomics, peptidomics and toponomics\u003cbr\u003e - Chemical biology\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface XV\u003c\/p\u003e \u003cp\u003eIntroduction XIX\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Protein Analytics 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Protein Purification 3\u003c\/p\u003e \u003cp\u003e2 Protein determination 23\u003c\/p\u003e \u003cp\u003e3 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Magnetic Resonance Spectroscopy of Biomolecules 433\u003c\/p\u003e \u003cp\u003e19 Electron Microscopy 485\u003c\/p\u003e \u003cp\u003e20 Atomic Force Microscopy 519\u003c\/p\u003e \u003cp\u003e21 X-Ray Structure Analysis 529\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Peptides, Carbohydrates, and Lipids 553\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22 Analytics of Synthetic Peptides 555\u003c\/p\u003e \u003cp\u003e23 Carbohydrate Analysis 571\u003c\/p\u003e \u003cp\u003e24 Lipid Analysis 613\u003c\/p\u003e \u003cp\u003e25 Analysis of Post-translational Modifications: Phosphorylation and Acetylation of Proteins 645\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Nucleic Acid Analytics 663\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e26 Isolation and Purification of Nucleic Acids 665\u003c\/p\u003e \u003cp\u003e27 Analysis of Nucleic Acids 681\u003c\/p\u003e \u003cp\u003e28 Techniques for the Hybridization and Detection of Nucleic Acids 719\u003c\/p\u003e \u003cp\u003e29 Polymerase Chain Reaction 755\u003c\/p\u003e \u003cp\u003e30 DNA Sequencing 785\u003c\/p\u003e \u003cp\u003e31 Analysis of Epigenetic Modifications 817\u003c\/p\u003e \u003cp\u003e32 Protein–Nucleic Acid Interactions 831\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V Functional and Systems Analytics 873\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e33 Sequence Data Analysis 875\u003c\/p\u003e \u003cp\u003e34 Analysis of Promoter Strength and Nascent RNA Synthesis 895\u003c\/p\u003e \u003cp\u003e35 Fluorescent In Situ Hybridization in Molecular Cytogenetics 917\u003c\/p\u003e \u003cp\u003e36 Physical and Genetic Mapping of Genomes 925\u003c\/p\u003e \u003cp\u003e37 DNA-Microarray Technology 945\u003c\/p\u003e \u003cp\u003e38 The Use of Oligonucleotides as Tools in Cell Biology 959\u003c\/p\u003e \u003cp\u003e39 Proteome Analysis 977\u003c\/p\u003e \u003cp\u003e40 Metabolomics and Peptidomics 1023\u003c\/p\u003e \u003cp\u003e41 Interactomics – Systematic Protein–Protein Interactions 1033\u003c\/p\u003e \u003cp\u003e42 Chemical Biology 1041\u003c\/p\u003e \u003cp\u003e43 Toponome Analysis 1057\u003c\/p\u003e \u003cp\u003eAppendix 1: Amino Acids and Posttranslational Modifications 1073\u003c\/p\u003e \u003cp\u003eAppendix 2: Symbols and Abbreviations 1075\u003c\/p\u003e \u003cp\u003eAppendix 3: Standard Amino Acids (three and one letter code) 1081\u003c\/p\u003e \u003cp\u003eAppendix 4: Nucleic Acid Bases 1083\u003c\/p\u003e \u003cp\u003eIndex 1085\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48743119126871,"sku":"9783527339198","price":67.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783527339198.jpg?v=1720064193"},{"product_id":"cell-and-molecular-biology-for-non-biologists-a-short-introduction-into-key-biological-concepts-9783662653555","title":"Cell and Molecular Biology for Non-Biologists: A","description":"\u003cb\u003eBook 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It lays the foundation for a systematic understanding of biology, which is essential in order to handle big data in biomedical research. Comprehension of what is measured, how it is measured and how to interpret results is a precondition for the development of novel therapies against diseases.Interdisciplinary research benefits from versatile approaches to generate and test hypotheses, which may lead to new discoveries. Therefore, it requires a new generation of biologists from diverse backgrounds - and they need this introduction.This book helps students and experts from e.g. computer science, informatics, mathematics, physics, and related fields or even if you are in sales and marketing and want to have a better understanding of the biology behind certain products.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1 Cell architecture.- 2 DNA \u0026amp; RNA \u0026amp; associated proteins.- 3 Transcription and translation.- 4 Regulation of gene expression.- 5 Membranes and intracellular transport.- 6 Signalling.- 7 Cell cycle.- 8 Immunology.- 9 Cancer.","brand":"Springer-Verlag Berlin and Heidelberg GmbH \u0026 Co. KG","offers":[{"title":"Default Title","offer_id":48743143309655,"sku":"9783662653555","price":59.99,"currency_code":"GBP","in_stock":true}]},{"product_id":"textbook-of-structural-biology-9789813142473","title":"Textbook Of Structural Biology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book provides a comprehensive coverage of the basic principles of structural biology, as well as an up-to-date summary of some main directions of research in the field. The relationship between structure and function is described in detail for soluble proteins, membrane proteins, membranes, and nucleic acids.There are several books covering protein structure and function, but none that give a complete picture, including nucleic acids, lipids, membranes and carbohydrates, all being of central importance in structural biology.The book covers state-of-the-art research in various areas. It is unique for its breadth of coverage by experts in the fields. The book is richly illustrated with more than 400 color figures to highlight the wide range of structures.","brand":"World Scientific Publishing Co Pte Ltd","offers":[{"title":"Default Title","offer_id":48743294763351,"sku":"9789813142473","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"membranes-to-molecular-machines-9780226625157","title":"Membranes to Molecular Machines","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eToday's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic channelsopen and close in our brain cell membranes; when we run, tiny motorsspin in our muscle cell membranes; and when we see, light operates molecular switchesin our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing proton pump inhibitors or medicines similar to Prozac.    Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as active matterin new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciencesfrom practitioner to historian to philosopher.    The research described in the book and its central actor, Dieter Oesterhelt, were honored with the 2021 Albert Lasker Basic Medical Research Awardfor his contribution to the development of optogenetics.","brand":"The University of Chicago Press","offers":[{"title":"Default Title","offer_id":48864237027671,"sku":"9780226625157","price":37.05,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780226625157.jpg?v=1722271018"},{"product_id":"once-we-all-had-gills-growing-up-evolutionist-in-an-evolving-world-9780253002358","title":"Once We All Had Gills Growing Up Evolutionist in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eRaff tells how and why he became an evolutionary biologist and describes some of the vibrant and living science of evolution\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eAt once a cri de coeur from an eminent scientist on behalf of his profession, Raff's work is also an engaging and informative jaunt through the richly diverse history of evolution as a phenomenon and a course of study.\u003c\/p\u003e * Publishers Weekly *\u003cbr\u003e\u003cp\u003eScience teachers and students, as well as working scientists and laypersons with some knowledge of biology, will find this an interesting and inspiring book, not only about the life and work of a scientist, but the importance of science to society as well.\u003c\/p\u003e * Foreword Reviews *\u003cbr\u003e\u003cp\u003eRaff's book is . . . a fascinating story of how a young boy interested in natural history became a scientist . . . and also a polemic arguing about the importance of science and its defense against the powers of ignorance.\u003c\/p\u003e * www.skepticblog.org *\u003cbr\u003e\u003cp\u003eThis is an excellent introduction to evolutionary thinking and an inspiration to those who may be just starting on their career (or those in need of a bit of encouragement to keep plugging along). . . . Highly recommended.\u003c\/p\u003e * Choice *\u003cbr\u003e\u003cp\u003eOnce We All Had Gills strikes just the right balance of drama, humor, good stories, and science that makes not only for entertaining reading, but also delivers important insights into evolutionary biology research.\u003c\/p\u003e * Quarterly Review of Biology *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface \u003cbr\u003eAcknowledgments\u003cbr\u003ePart I: Becoming a Naturalist\u003cbr\u003e1. Space-Time\u003cbr\u003e2. Layers of the Past\u003cbr\u003e3. An Age of Dinosaurs\u003cbr\u003e4. A School a Minute\u003cbr\u003e5. In the Natural World\u003cbr\u003e6. Transformations\u003cbr\u003e7. Going South\u003cbr\u003e8. Learning to Love the Bomb\u003cbr\u003e9. On the Road to Chiapas\u003cbr\u003e10. The Masked Messenger\u003cbr\u003ePart II: Finding Evolution, Founding Evo-Devo\u003cbr\u003e11. Evolution as Science\u003cbr\u003e12. Dining with Darwin\u003cbr\u003e13. Life with Sea Urchins\u003cbr\u003e14. Embryos Evolving\u003cbr\u003e15. Evolution in the Tasman Sea\u003cbr\u003e16. An Alternate Present\u003cbr\u003e17. Biology Meets Fossils \u003cbr\u003ePart III: Strange New World\u003cbr\u003e18. Darwin's Day in Court\u003cbr\u003e19. Creationist Makeovers\u003cbr\u003e20. Evolution Matters\u003cbr\u003eSelected Bibliography\u003cbr\u003eIndex\u003c\/p\u003e","brand":"Indiana University Press","offers":[{"title":"Default Title","offer_id":48864292864343,"sku":"9780253002358","price":23.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780253002358.jpg?v=1722271263"},{"product_id":"case-studies-in-infectious-disease-9780367696399","title":"Case Studies in Infectious Disease","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cem\u003eCase Studies in Infectious Disease\u003c\/em\u003e presents 40 case studies featuring the most important human infectious diseases worldwide. Fully revised and updated in this second edition, the book describes the natural history of infection from point of entry of the pathogen through to clinical management of the resulting disease or condition. A further 8 case studies have been provided online as supplementary material, and these can be downloaded by students. \u003c\/p\u003e\u003cp\u003eFive core sets of questions are posed in each case, with the answers covering the nature of the infectious agent, route(s) of spread and of infection, pathogenesis of disease, host response to infection, clinical manifestations, diagnosis, treatment and prevention. This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms and diseases, fully integrating microbiology and immunology throughout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eKEY FEATURES\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eHigh-resolution photos accompany each case, from the causative agents of disease to the clinical manifestations of the infection.\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eExquisite artwork helps to illustrate important concepts throughout the book. \u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eEight new cases added to this new edition, extending coverage of important infectious diseases of worldwide significance. \u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eA standardized set of core questions allows students to compare directly differences between microbes such as their structure, clinical manifestations, host response, pathogenesis and availability of vaccines.\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eQuestions and answers available online, test the readerâs understanding of each case study.\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eThe book provides essential case-based learning for undergraduate and graduate microbiology students, while medical students and trainee physicians will also find the up-to-date information on 48 globally important infectious diseases outlined in a clear, digestible form, invaluable during undergraduate studies and in future clinical practice. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\"a handsome, excellent book on most common pathogens, with a clear orientation to immunology, physiopathology, and microbiology … It reads well and is an excellent textbook for medical students and a good source of illustrations, tables, and question ideas for teachers.\" Gary P. Wormser and Guillaume Béraud for \u003cem\u003eClinical Infectious Diseases.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\"a valuable compilation of information on the most common diseases that cause illness and death worldwide. The presentation format with distinct sections makes it readable and well suited for either students just learning about the pathogens causing infectious disease or clinicians who need an update. The level of detail is well thought out and gives the reader a useful summary of each pathogen and disease state. The condensed presentations make it a good reference source for those with insufficient time to read through more detailed textbooks.\" Philip S. Brachman for \u003ci\u003eEmerging Infectious Disease.\u003c\/i\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eAspergillus fumigatus\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eBorrelia burgdorferi\u003c\/i\u003e and related species \u003c\/p\u003e\u003cp\u003e\u003ci\u003eCampylobacter jejuni\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eCandida albicans\u003c\/i\u003e\u003c\/p\u003e\u003cp\u003e\u003ci\u003eChlamydia trachomatis\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eClostridiodies\u003c\/i\u003e \u003ci\u003edifficile\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003eCytomegalovirus \u003c\/p\u003e\u003cp\u003e\u003ci\u003eEchinococcus\u003c\/i\u003e spp. \u003c\/p\u003e\u003cp\u003eEnteroviruses\u003c\/p\u003e\u003cp\u003eEpstein-Barr virus \u003c\/p\u003e\u003cp\u003e\u003ci\u003eEscherichia coli\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eGiardia lamblia\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eHelicobacter pylori\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003eHepatitis B virus \u003c\/p\u003e\u003cp\u003eHepatitis C virus\u003c\/p\u003e\u003cp\u003eHerpes simplex virus \u003c\/p\u003e\u003cp\u003e\u003ci\u003eHistoplasma capsulatum\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003eHuman immunodeficiency virus \u003c\/p\u003e\u003cp\u003eInfluenza virus \u003c\/p\u003e\u003cp\u003e\u003ci\u003eLeishmania\u003c\/i\u003e spp. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eLeptospira\u003c\/i\u003e spp. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eListeria monocytogenes\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eMycobacterium leprae\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eMycobacterium tuberculosis\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNeisseria gonorrhoeae\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNeisseria meningitidis\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003eNorovirus \u003c\/p\u003e\u003cp\u003e\u003ci\u003ePlasmodium\u003c\/i\u003e spp. \u003c\/p\u003e\u003cp\u003eRespiratory syncytial virus \u003c\/p\u003e\u003cp\u003e\u003ci\u003eRickettsia\u003c\/i\u003e spp. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eSalmonella typhi\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eSchistosoma\u003c\/i\u003e spp. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eStaphylococcus aureu\u003c\/i\u003es \u003c\/p\u003e\u003cp\u003e\u003ci\u003eStreptococcus pneumoniae\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eStreptococcus pyogenes\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eToxoplasma gondii\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eTrypanosoma\u003c\/i\u003e spp.\u003c\/p\u003e\u003cp\u003e\u003ci\u003eTrichophyton spp.\u003c\/i\u003e and dermatophytes\u003cbr\u003e\u003cbr\u003eVaricella-zoster virus \u003c\/p\u003e\u003cp\u003e\u003ci\u003eWuchereria bancrofti\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003ePlus online cases:\u003c\/p\u003e\u003cp\u003e\u003ci\u003eBartonella bacilliformis\u003c\/i\u003e \u003cbr\u003e\u003cbr\u003e\u003cem\u003eBrucella\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003ci\u003eCoxiella burnetti\u003c\/i\u003e \u003c\/p\u003e\u003cp\u003eDengue virus\u003cbr\u003e\u003cbr\u003e\u003cem\u003eEnterococcus faecalis and E. faecium\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003ci\u003eMycobacterium abscessus\u003c\/i\u003e\u003c\/p\u003e\u003cp\u003eSARS-CoV-2 \u003c\/p\u003e\u003cp\u003e\u003ci\u003eStreptococcus mitis\u003c\/i\u003e \u003c\/p\u003e","brand":"Taylor \u0026 Francis Ltd","offers":[{"title":"Default Title","offer_id":48864516538711,"sku":"9780367696399","price":49.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"strange-glow-9780691178349","title":"Strange Glow","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eWinner of the 2017 PROSE Award in History of Science, Medicine \u0026amp; Technology, Association of American Publishers One of Physics World's Top Ten Books of the Year, 2016 One of Choice's Outstanding Academic Titles for 2016 #6 on The Telegraph's Top 50 Books of the Year 2016 One of Smithsonian Magazine's Best Science Books of 2016 Shortlisted for Physics World's Book of the Year 2016 \"Jorgensen walks readers through the history of humanity's interaction with radiation... [Strange Glow] is a solid, accessible work, but perhaps its most beneficial aspect is that Jorgensen equips readers with enough knowledge to make their own risk assessments, whether it is of a potential medical diagnostic test or a particular consumer decision.\"--Publishers Weekly \"Unbiased, comprehensible information on radiation risk is hard to come by...Strange Glowfills this gap.\"--Science \"Narrative science at its best ... a propulsive story, each piece building on the next in a series of progressive revelations... A seismic piece of scientific inquiry, top shelf in narrative style and illumination.\"--Kirkus, starred review \"The only antidote to irrational fear is knowledge, andStrange Glowimparts this in spades.\"--Independent \"Strange Glow isn't about lessening what is largely a sensible fear, but about removing some of the mystery and misunderstanding... This is a long overdue and successful attempt to rationalise an emotional subject by telling its story in very human terms.\"--Engineering \u0026amp; Technology News \"Strange Glow ... integrates detailed science and carefully illuminated medical statistics with the personal lives of scientists... The book's goal--'to present the facts about radiation as objectively and even-handedly as possible, leaving you to decide which aspects to fear'--is achieved with authority and style.\"--Andrew Robinson, Lancet \"This book can be enjoyed as a sort of scientific QI--a string of interesting facts you can't wait to share with anyone who can be persuaded to listen... Jorgensen proves that there's no excuse for convoluted writing, however difficult the subject. His conversational style makes even the most complex equations seem attractive.\"--William Cook, The Spectator \"[Strange Glow] is ... the story of human interaction with radiation--beginning with the one type that we can see (light) and continuing through radio waves, atomic blasts, cellphones, radon, microwave ovens, luggage scanners, the Fukushima accident, and on and on... Jorgensen avoids graphs and numbers, instead relying largely on entertaining--if alarming--anecdotes.\"--Nancy Szokan, Washington Post \"What I certainly did not expect was to get caught up in the stories of the scientists [in Strange Glow]... Jorgensen has written a compelling book about the history of radiation... [His] gift is that he make us care about the scientists.\"--Jacqueline Cutler, Newark Star-Ledger \"Strange Glow is a cracking good read, filled with fascinating stories about the people behind the science.\"--Literary Review \"Timothy Jorgensen is a scientist with a knack for narrative storytelling.\"--Ryan Stellabotte, Fordham News \"Strange Glow is clear, engaging and refreshingly willing to treat the reader as a thinking adult.\"--Japan Times \"Strange Glow is a fantastic, well-written book about the benefits and risks of radiation. Jorgenson uses common prose so that a wide range of readers can follow the discussions...The book includes extensive, useful, and lucid discussions on medical x-rays and radon gas. Readers also learn the facts regarding the Three Mile Island, Chernobyl, and Fukushima nuclear reactor meltdowns and the problems they cause. [A] well-researched book.\"--Choice \"Informative, fast paced and entertaining... I guarantee you will be engaged and surprised.\"--Chemistry World \"Jorgensen's lucid writing and strong story-telling skills are demonstrated thoroughly in this book, making it a pleasure to read... In its simplicity and conciseness, it greatly contributes to removing some of the mystery and misunderstanding that surrounds radiation... I feel it will become a very useful resource to the general public as well as to radiation experts.\"--Jun Deng, Physics World \"A narrative history, which integrates detailed science and statistics with the personal lives of the pioneers. [Jorgensen's] goal--'to present the facts about radiation as objectively and even-handedly as possible, leaving you to decide which aspects to fear'--is achieved with authority and style.\"--Andrew Robinson, The Telegraph \"Jorgenson lays out the progression of mankind's understanding of radiation science over the past century, including the figures, breakthroughs and disasters that moved the field forward (for better or worse). An informative read that chronicles the history and science of humankind's 'ambivalent' relationship with this strange force.\"--Rachel Gross, Smithsonian \"[Jorgensen] ... has chosen another original but interesting and straightforward way of storytelling, devoid of scientific jargon, to achieve the aim of reaching the widest possible audience of readers, regardless to their technical background... Strange Glow: The Story of Radiation ... Will certainly be useful due to the striking and exciting style of its presentation.\"--R.M. Alexakhin, Radiation Protection Dosimetry\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePREFACE ix  1. Nuclear Jaguars 1  PART ONE: RADIATION 101: THE BASICS  2. Now You See It: Radiation Revealed 7  3. Seek and You Shall Find: Radioactivity Everywhere 38  4. Splitting Hairs: Atomic Particles and Nuclear Fission 51  PART TWO: THE HEALTH EFFECTS OF RADIATION  5. Painted into a Corner: Radiation and Occupational Illness 81  6. The Hippocratic Paradox: Radiation Cures Cancer 116  7. Location, Location, Location: Radiation Sickness 141  8. Snow Warning: Radioactive Fallout 164  9. After the Dust Settles: Measuring the Cancer Risk of Radiation 187  10. Breeding Season: Genetic Effects 206  11. Crystal Clear: The Target for Radiation Damage 234  PART THREE: WEIGHING THE RISKS AND BENEFITS OF RADIATION  12. Silent Spring: Radon in Homes 275  13. A Tale of Two Cities: Diagnostic Radiography 293  14. Sorry, Wrong Number: Cell Phones 310  15. Hot Tuna: Radioactivity in Food 326  16. Blue Moon: Nuclear Power Plant Accidents 346  17. The Things They Carried: Geopolitical Radiation Threats 374  Epilogue: N-Rays 397  ACKNOWLEDGMENTS 407  NOTES AND CITATIONS 411  BIBLIOGRAPHY 453  INDEX 465","brand":"Princeton University Press","offers":[{"title":"Default Title","offer_id":48865538769239,"sku":"9780691178349","price":16.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780691178349.jpg?v=1722274455"},{"product_id":"remnants-of-ancient-life-9780691221144","title":"Remnants of Ancient Life","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"Winner of the PROSE Award in Earth Science, Association of American Publishers\"\u003cbr\u003e\"[A] vivid, gripping book. . . . Dale Greenwalt . . . has written a riveting account of a field achieving revolutionary insights.\"\u003cb\u003e---Simon Ings, \u003ci\u003eNew Scientist\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\"[An] eye-opening guide to this new world of understanding, one that encompasses chemistry along with biology.\"\u003cb\u003e---David P. Barash, \u003ci\u003eWall Street Journal\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\"An accessible book on ancient life that focuses as much on chemistry as on biology.\"\u003cb\u003e---Wade Lee-Smith, \u003ci\u003eLibrary Journal\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\"[Fascinating] . . . an unabashedly excited report from the front lines\"\u003cb\u003e---Steve Donoghue, \u003ci\u003eOpen Letters Review\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\"The book provides a fascinating journey through the very latest in research into the origins of life on Earth. . . . No one should be intimidated by this highly readable work.\"\u003cb\u003e---David Gascoigne, \u003ci\u003eTravels with Birds\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\"If you think you cannot stomach yet another popular book on palaeontology, think again. \u003ci\u003eRemnants of Ancient Life\u003c\/i\u003e is as fascinating as the inviting cover and subtitle suggest, managing to put a completely fresh gloss on the topic of palaeontology.\"\u003cb\u003e---Leon Vlieger, \u003ci\u003eThe Inquisitive Biologist\u003c\/i\u003e\u003c\/b\u003e","brand":"Princeton University Press","offers":[{"title":"Default Title","offer_id":48865550467415,"sku":"9780691221144","price":19.8,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780691221144.jpg?v=1722274516"},{"product_id":"molecular-cell-biology-for-dummies-9781119620402","title":"Molecular  Cell Biology For Dummies","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eIntroduction 1\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 1: The World of the Cell 5\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 1: Exploring the World of the Cell 7\u003c\/p\u003e \u003cp\u003eChapter 2: Take a Tour inside the Cell 13\u003c\/p\u003e \u003cp\u003eChapter 3: Dead or Alive: Viruses 35\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 2: Molecules: The Stuff of Life 51\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 4: Better Living through Chemistry 53\u003c\/p\u003e \u003cp\u003eChapter 5: Carbohydrates: How Sweet They Are 77\u003c\/p\u003e \u003cp\u003eChapter 6: Proteins: Workers in the Cellular Factory 87\u003c\/p\u003e \u003cp\u003eChapter 7: DNA and RNA: Instructions for Life 103\u003c\/p\u003e \u003cp\u003eChapter 8: Lipids: Waterproof and Energy Rich 113\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 3: The Working Cell 121\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 9: Hello, Neighbor: How Cells Communicate 123\u003c\/p\u003e \u003cp\u003eChapter 10: Metabolism: Transferring Energy and Matter 139\u003c\/p\u003e \u003cp\u003eChapter 11: Cellular Respiration: Every Breath You Take 159\u003c\/p\u003e \u003cp\u003eChapter 12: Photosynthesis: Makin’ Food in the Kitchen of Life 187\u003c\/p\u003e \u003cp\u003eChapter 13: Splitsville: The Cell Cycle, Cell Division, and Cancer 203\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 4: Genetics: From One Generation to the Next 219\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 14: Meiosis: Getting Ready for Baby 221\u003c\/p\u003e \u003cp\u003eChapter 15: Genetics: Talkin’ ’Bout the Generations 233\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 5: Molecular Genetics: How Cells Read the Book of Life 261\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 16: DNA Replication: Doubling Your Genetic Stuff 263\u003c\/p\u003e \u003cp\u003eChapter 17: Transcription and Translation: What’s in a Gene?  273\u003c\/p\u003e \u003cp\u003eChapter 18: Control of Gene Expression: It’s How You Play Your Cards That Counts 291\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 6: Molecular Biology: Harnessing the Power of DNA 311\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 19: The Book of You: Reading Your Genes 313\u003c\/p\u003e \u003cp\u003eChapter 20: Rewriting the Code of Life: Recombinant DNA Technology and Genome Editing 331\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 7: The Part of Tens 349\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChapter 21: Ten Important Rules for Cells to Live By 351\u003c\/p\u003e \u003cp\u003eChapter 22: Ten Ways to Improve Your Grade 361\u003c\/p\u003e \u003cp\u003eIndex 369\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48866406465879,"sku":"9781119620402","price":16.14,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119620402.jpg?v=1722278495"},{"product_id":"molecular-plant-breeding-9781845939823","title":"Molecular Plant Breeding","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eNow available in paperback, Molecular Plant Breeding provides an integrative overview of issues from basic theories to their applications to crop improvement. Chapters include discussions of breeding methodology, quantitative genetics, genomics and bioinformatics and present statistical issues related to gene mapping, marker-assisted selection and genotype by environment interactions in clear and concise language. Providing an integrated profile of molecular breeding in plants, this book will be an essential resource for researchers and students involved in plant biology and breeding, genetics and applied genomics.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Introduction 2: Molecular Breeding Tools: Markers and Maps 3: Molecular Breeding Tools: Omics and Arrays 4: Populations in Genetics and Breeding 5: Plant Genetic Resources: Management, Evaluation and Enhancement 6: Molecular Dissection of Complex Traits: Theory 7: Molecular Dissection of Complex Traits: Practice 8: Marker-assisted Selection: Theory 9: Marker-assisted Selection: Practice 10: Genotype-by-environment Interaction 11: Isolation and Functional Analysis of Genes 12: Gene Transfer and Genetically Modified Plants 13: Intellectual Property Rights and Plant Variety Protection 14: Breeding Informatics 15: Decision Support Tools","brand":"CABI Publishing","offers":[{"title":"Default Title","offer_id":48868701307223,"sku":"9781845939823","price":68.78,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781845939823.jpg?v=1722289294"},{"product_id":"essentials-of-nucleic-acid-analysis-9780854043675","title":"Essentials of Nucleic Acid Analysis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOver the last decade there has been a rapid development of molecular techniques, with an increasing range of instrumentation now available. The development of accompanying reference literature has not kept pace with technological advances and this poses significant challenges to the analyst. Essentials of Nucleic Acid Analysis sets out to guide the analyst through the steps needed to obtain good quality results in DNA analysis. The underlying principles for achieving this goal were formulated by LGC (formerly the Laboratory of the Government Chemist) as the six principles for ensuring valid analytical measurement, which are detailed in the introduction. The reader is also provided with guidelines for method validation and quality control of established and emerging DNA measurement techniques. The authors of each chapter are practitioners of the art of DNA analysis in areas where the quality of the result is critical. 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Sometimes they constitute the most usual cause of death in children aged less than five years, with pneumonia like the leading origin. In Chapter One, the epidemiology (community-acquired and hospital-acquired pneumonia), causes, risk factors and clinical basic aspects of bacterial pneumonia are presented. The genus Enterococcus coexists with several Gram-positive bacteria. Chapter Two discusses how new tools must be developed to track glycopeptide resistance dissemination by using ISs as markers in epidemiological investigations across the world. 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The potential uses of tumour markers are screening in the general population, differential diagnoses of symptomatic patients, clinical staging of cancer, estimating tumour volume, indicating prognosis, monitoring treatment and detecting recurrences. In order to obtain maximum clinical benefit, a tumour marker should have some characteristics. A tumour marker should be tissue-specific. The plasma level of the tumour marker should be in proportion to the size and activity of the tumour. A tumour marker should be present in plasma at a detectable level, even though tumour size is very small. A tumour marker should reflect the altered tumour characteristic as a response to therapy. Unfortunately, currently used tumour markers do not meet all of these criteria. A majority of them are present in normal, benign and tumour tissues, and unfortunately, they are not specific enough to be used for cancer screening in the general population. In addition, conventional tumour markers are poor in reflecting altered tumour behavior in response to anticancer therapy. They are of most value during follow-up appointments. Recent developments in molecular biology have led to the identification of numerous new tumour biomarkers. Firstly, the detection of DNA and RNA freely circulating in blood has provided a new perspective for the early diagnosis of cancer, patient follow-up, and assessment of therapy efficacy. Circulating free nucleic acids can originate from both malignant and non-malignant tissues. Discrimination of tumour cells is based on the presence of tumour-specific genetic and epigenetic alterations. This circulating nucleic acid-based approach is termed a liquid biopsy. Due to its non-invasive and repeatable features, liquid biopsy is a promising tool for cancer patients. It is particularly helpful in cancers where solid tissue biopsies are not feasible, and in the metastatic patients when multiple distinct tumour masses are simultaneously present. As another advantage, liquid biopsy shows the current tumour dynamics during anticancer therapy and drug sensitivities that conventional examinations fail to reflect. Secondly, self-renewable stem cells have the potential to cause cancer. If stem cells are genetically or epienetically changed, their differentiation potential becomes impaired and their proliferative capacity becomes uncontrolled. Current anticancer therapies mostly fail to eradicate cancer stem cells and instead favor expansion of the cancer stem cell pool and\/or select for resistant stem cells. Thirdly, microRNAs, non-coding RNAs and transfer RNA fragments found in the bloodstream are candidate markers for the diagnosis and prognosis of different types of cancer. This book provides an overview of these new molecular tumour markers.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886102786391,"sku":"9781536143676","price":163.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781536143676.jpg?v=1722538826"},{"product_id":"foldases-catalyzing-the-formation-isomerization-of-disulfide-bonds-in-proteins-9781606924662","title":"Foldases Catalyzing the Formation \u0026 Isomerization","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOne of the rate-limiting steps in the folding pathways of many secretory proteins is the formation of correct disulfide bonds between cysteine residues. In eukaryotes, both disulfide bond formation and isomerisation which shuffles incorrectly formed disulfides are catalysed by protein disulfide isomerase (PDI), whereas in bacteria these two reactions are catalysed by separate enzymes. Both in eukaryotic and prokaryotic cells the oxidation and isomerisation steps proceed exclusively in extracytoplasmic environments (the lumen of the eukaryotic endoplasmic reticulum and the Gram-negative bacterial periplasmic space). The family of foldases under discussion is characterised by a conserved \"thioredoxin fold\" and a common active site motif: Cys-X-X-Cys. The process of disulfide bond formation relies on thiol-disulfide exchange between oxidised and reduced cysteine pairs in the catalyst and substrate protein. Two separate pathways involved in disulfide bond formation and isomerisation have been characterised both in eukaryotes and in bacteria. In the oxidative pathway, oxidizing equivalents flow from oxygen to a membrane protein (Ero1p in eukaryotes or DsbB in bacteria), and then to a folding protein containing reduced cysteines via PDI (in eukaryotes) or via DsbA (in bacteria). 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Chapter Five reviews the historical aspect of how major biological roles of G-quadruplexes have been uncovered by the use of specifically designed small molecule probes; and discusses the future applications of G-quadruplex interacting small molecules, including the development as potential drug candidates. Chapter Six focuses on the latest advances in the development of the telomerase assays and the authors further discuss the application potentiality of the assays for clinical samples.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48887245144407,"sku":"9781634855129","price":163.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781634855129.jpg?v=1722543665"},{"product_id":"drug-discovery-for-leishmaniasis-9781782628897","title":"Drug Discovery for Leishmaniasis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eFor human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides.   Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania.   Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eThis is a timely and highly relevant book that provides a comprehensive and in-depth overview of the current state and future directions of drug discovery for leishmaniasis. It has a broad scientific scope and wonderful insights from leading experts in the field which ensures that there is something for everyone, and that this book is truly a must-have for anyone working in the area of leishmaniasis. -- Dr. Steven L. Cobb, Durham University (UK) * ChemMedChem, DOI: 10.1002\/cmdc.201800266 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eLeishmaniasis, Impact and Therapeutic Needs; Anti-leishmanial Drug Discovery: Past, Present and Future Perspectives; From Bench to Bedside: Development and Optimization of Clinical Therapies for Visceral Leishmaniasis; Drug Assay Methodology in Leishmaniasis: From the Microplate to Image Analysis; The Pursuit of Novel Anti-leishmanial Agents by High-throughput Screening (HTS) of Chemical Libraries; Omics and Their Impact on the Development of Chemotherapy Against Leishmania; In silico Tools for Target Identification and Drug Molecular Docking in Leishmania; Medicinal Chemistry Strategies to Discover New Leishmanicidal Drugs; Natural Products as a Source of New Drugs Against Leishmania; Organometallic Compounds in Chemotherapy Against Leishmania; New Avenues for Drug Delivery in Leishmania: Using Treatment of Visceral Leishmaniasis with Amphotericin B as an Exemplar; Addressing the Molecular Biology of Leishmania for Drug Development; The Physical Matrix of the Plasma Membrane as a Target: The Charm of Drugs with Low Specificity; Nutrient Transport and Sensing as Pharmacological Targets for Leishmaniasis; Carbon Metabolism as a Drug Target in Leishmania; The Redox Metabolism and Oxidative Stress in Leishmania as a Crossroads for the Lethal Effect of Drugs; DNA Topoisomerases as Promising Targets for Leishmania Chemotherapy; Molecular Basis of Drug Resistance in Leishmania; The Macrophage–Parasite Interface as a Chemotherapeutic Target in Leishmaniasis","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48887693410647,"sku":"9781782628897","price":141.55,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781782628897.jpg?v=1722545773"},{"product_id":"rna-polymerases-as-molecular-motors-on-the-road-9781788013659","title":"RNA Polymerases as Molecular Motors: On the Road","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eTo thrive, every living cell must continuously gauge and respond to changes in its environment. 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Maintaining the much-praised clarity of previous editions, this edition incorporates both new techniques and pivotal discoveries in a succinct, easy-to-digest way, using updated figures and diagrams to help explain complex processes.Updated content on the manipulation of DNA and genes reflects the rapid introduction of new methods in contemporary research, and incorporates up-to-date discussions of recent developments such as gene editing. Chapter summaries are logically laid out, forming bulleted lists which provide students with a consolidation of difficult concepts and progressively guide them through the specifics whilst keeping the big picture in mind. Additional ''find out more'' sections provide helpful problem-solving support and the further reading is divided into types to cater for broader learning needs.With an integrated approach covering bo\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eEasy to read with good use of simple figures and plenty of internal cross-references to other chapters or relevant pages. I was impressed with the inclusion of some very up to date findings. * Dr Peter Morris, School of Life Sciences, Heriot-Watt University *\u003cbr\u003eI don't know of any other biology\/biochemistry book that explains DNA replication as well as this one. * Lynn Rogers, School of Molecular and Biomedical Science, Adelaide University *\u003cbr\u003eThe style is very clear, logical and systematic. The diagrams complement the text well. * Dr Momna Hejmadi, Department of Biology and Biochemistry, University of Bath *\u003cbr\u003eGood entry level biochemistry textbook that gives students an overview of the diversity of biochemistry and that introduces abstract concepts in a well-explained and accessible way. * Dirk Wildeboer, Natural Sciences, Middlesex University *\u003cbr\u003eThis textbook presents classical biochemistry material with a balanced emphasis on details and conceptual understanding. Explanations are given in a conversational manner so that students are not distracted by an over-whelming amount of new terminology. * Amanda Storm, Biology, James Madison University *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart 1: Basic concepts of life 1: The basic molecular themes of life 2: Cells and viruses 3: Energy considerations in biochemistryPart 2: Structure and function of proteins and membranes 4: The structure of proteins 5: Methods in protein investigation 6: Enzymes 7: The cell membrane and membrane proteins 8: Muscle contraction, the cytoskeleton, and molecular motorsPart 3: Metabolism and nutrition 9: General principles of nutrition 10: Food digestion, absorption and distribution to the tissues 11: The storage fuels: Mechanisms of transport, storage, and mobilization of carbohydrate and fat 12: Principles of energy release from food 13: Glycolysis, the TCA cycle, and the electron transport system 14: Energy release from fat 15: An alternative pathway of glucose oxidation: The pentose phosphate pathway 16: Synthesis of glucose (gluconeogenesis) 17: Synthesis of fat and related compounds 18: Nitrogen metabolism: amino acid metabolism 19: Nitrogen metabolism: nucleotide metabolism 20: Mechanisms of metabolic control and their applications to metabolic integration 21: Raising electrons of water back up the energy scale: photosynthesisPart 4: Information storage and utilization 22: The genome 23: DNA synthesis, repair and recombination 24: Gene transcription 25: Protein synthesis and controlled protein breakdown 26: Control of gene expression 27: Protein sorting and delivery 28: Manipulating DNA and genesPart 5: Cells and tissues 29: Cell signalling 30: The cell cycle, cell division, cell death and cancerPart 6: Protective mechanisms against disease 31: Blood clotting, xenobiotic metabolism, and reactive oxygen species 32: The immune system","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":49083398881623,"sku":"9780198768111","price":55.09,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198768111.jpg?v=1725548812"},{"product_id":"hidden-beauty-exploring-the-aesthetics-of-medical-science-9780764344121","title":"Hidden Beauty Exploring the Aesthetics of Medical","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Schiffer Publishing Ltd","offers":[{"title":"Default Title","offer_id":49083618525527,"sku":"9780764344121","price":39.09,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780764344121.jpg?v=1725549509"},{"product_id":"understanding-evodevo-9781108819466","title":"Understanding EvoDevo","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWhy do the best-known examples of evolutionary change involve the alteration of one kind of animal into another very similar one, like the evolution of a bigger beak in a bird? Wouldn''t it be much more interesting to understand how beaks originated? Most people would agree, but until recently we didn''t know much about such origins. That is now changing, with the growth of the interdisciplinary field evo-devo, which deals with the relationship between how embryos develop in the short term and how they (and the adults they grow into) evolve in the long term. One of the key questions is: can the origins of structures such as beaks, eyes, and shells be explained within a Darwinian framework? The answer seems to be yes, but only by expanding that framework. This book discusses the required expansion, and the current state of play regarding our understanding of evolutionary and developmental origins.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e'Wallace Arthur treats his readers to an eminently readable but still deeply rooted introduction into one of the most significant achievements of evolutionary biology: how evolutionary developmental biology put the organism back into the centre of evolutionary thinking.' Günter P. Wagner, Yale University, USA\u003cbr\u003e'Evo-devo deals with the multiple connections that exist between the biological processes of evolution and development. However, as an interface subject, there is a plurality of views on its content and its boundaries. In spite of that, Wallace Arthur has succeeded in writing an extremely clear and highly accessible guide to this fascinating, multifaceted discipline. Using the concept of 'developmental repatterning' as a common thread, the book provides a balanced view of evo-devo, covering its main achievements and future challenges. This is an ideal entry point for the non-specialist, but also a stimulating read for the practitioner who wants to consider her\/his research in a wider perspective.' Giuseppe Fusco, University of Padova, Italy\u003cbr\u003e'Occasionally I feel that the field of Evolution and Development has lost its way, becoming submerged in myriad examples and details that don't expand our understanding of life. Wallace's book expounds the intellectual underpinnings of Evolution and Development, leads us through the key questions, and finally shows how the details and examples inform our future understanding. This book provides not just a guide to Evolution and Development, but also a spur to refocus and redouble our efforts to use development to help understand the evolution of life on Earth.' Peter Dearden, University of Otago, New Zealand\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface; Acknowledgements; 1. What is evo-devo and why is it important?; 2. Antecedents of evo-devo; 3. Evolutionary and developmental essentials; 4. Evo-devo essentials; 5. The evolution of variations on a theme; 6. The evolutionary origins of themes and novelties; 7. The evolutionary origins of body plans; 8. Body plan features and toolkit genes; 9. Bringing it all together; Concluding remarks; Summary of common misunderstandings; References; Index.","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":49083834990935,"sku":"9781108819466","price":13.94,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781108819466.jpg?v=1725550169"},{"product_id":"wilson-and-walkers-principles-and-techniques-of-biochemistry-and-molecular-biology-9781316614761","title":"Wilson and Walkers Principles and Techniques of","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eBringing this best-selling textbook right up to date, the new edition uniquely integrates the theories and methods that drive the fields of biology, biotechnology and medicine, comprehensively covering both the techniques students will encounter in lab classes and those that underpin current key advances and discoveries. The contents have been updated to include both traditional and cutting-edge techniques most commonly used in current life science research. Emphasis is placed on understanding the theory behind the techniques, as well as analysis of the resulting data. New chapters cover proteomics, genomics, metabolomics, and bioinformatics, as well as data analysis and visualisation. Using accessible language to describe concepts and methods, and with a wealth of new in-text worked examples to challenge students'' understanding, this textbook provides an essential guide to the key techniques used in current bioscience research.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e'After seven editions between 1975 and 2010 this essential textbook has undergone a major update. The new editors, Drs Hofmann and Clokie, recruited many experts to revise individual chapters and added a significant amount of new material, thus making the book even more valuable. This eighth edition is basically a new book that covers the techniques of biochemistry and molecular biology in a very comprehensive manner - it does not go into great detail, but gives the reader a good introduction to all of them. Each chapter contains suggestions for further reading for those in need of a follow-up. Excellent diagrams and illustrations provide help in comprehension of the presented material. Since this text is largely aimed at undergraduate students, it fulfils its role extremely well.' Alexander Wlodawer, National Cancer Institute at Frederick\u003cbr\u003eReview from previous edition: 'This book deserves a place in any modern pathology department and brings together a body of information which is traditionally scattered across several texts … it also represents excellent value for money.' Annals of Clinical Biochemistry\u003cbr\u003eReview from previous edition: 'It is necessary to have a practical up to date guide to experimental techniques at hand in a laboratory. This book belongs to such kind of texts. It covers all branches of basic as well as advanced techniques. The book represents a fundamental guidebook for work in a laboratory.' Photosynthetica\u003cbr\u003eReview from previous edition: 'The book is well illustrated, indexed, free of errors and most chapters have problem sets with worked answers. The book is written for 'all bioscience undergraduate students and pre-medical students for whom practical biochemistry, molecular biology and immunology form part of the syllabus' … it is a very good supplement for undergraduate courses in general biochemistry or a text for courses in biochemical techniques. [This book] is also recommended for graduate students and other researchers in applied sciences such as food biochemistry.' Journal of Food Biochemistry\u003cbr\u003eReview from previous edition: '… well-written and comprehensive … what truly distinguishes this text from others of its kind are the outstanding chapters on proteins, mass spectrometry and spectroscopic techniques. … a valuable resource for undergraduate or graduate students taking introductory or advanced techniques\/laboratory courses in cell\/molecular biology, biochemistry or biotechnology.' Microbiology Today\u003cbr\u003eReview from previous edition: 'I found this volume remarkably satisfying in that it answered all those 'why do you do it like this?' type questions. … This book has already received extensive reference value on my bookshelf.' Journal of Biological Education\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eForeword Keith Wilson and John Walker; Preface Samuel Clokie and Andreas Hofmann; Tables and resources Andreas Hofmann; 1. Life science studies Samuel Clokie and Andreas Hofmann; 2. Basic principles Parisa Amani and Andreas Hofmann; 3. Cell culture techniques Anwar Baydoun; 4. Recombinant DNA techniques and molecular cloning Ralph Rapley; 5. Preparative biochemistry Samuel Clokie; 6. Electrophoresis Ralph Rapley; 7. Immunochemical techniques Katja Fischer; 8. Flow cytometry John Grainger and Joanne Konkel; 9. Radioisotope techniques Robert Slater; 10. Clinical biochemistry Gillian Rumsby; 11. Microscopy Stephen Paddock; 12. Centrifugation Kay Ohlendieck and Stephen Harding; 13. Spectroscopic techniques Anne Simon and Andreas Hofmann; 14. Basic techniques probing molecular structure and interactions Anne Simon and Joanne Macdonald; 15. Mass spectrometric techniques Sonja Hess and James MacRae; 16. Fundamentals of bioinformatics Cinzia Cantacessi and Anna Protasio; 17. Fundamentals of cheminformatics Paul Taylor; 18. The Python programming language Timothy Stevens; 19. Processing and visualisation of experimental data Jean-Baptiste Cazier; 20. Fundamental genome sequencing and annotation Pasi Korhonen and Robin Gasser; 21. Fundamentals of proteomics Sonja Hess and Michael Weiss; 22. Fundamentals of metabolomics James MacRae; 23. Enzymes and receptors Megan Cross and Andreas Hofmann; 24. Drug discovery and development David Camp.","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":49083862516055,"sku":"9781316614761","price":41.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781316614761.jpg?v=1725550252"},{"product_id":"essential-bioinformatics-9781680945225","title":"Essential Bioinformatics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eA flood of data means that many of the challenges in biology are now challenges in computing. Bioinformatics, the application of computational techniques to analyse the information associated with biomolecules on a large-scale, has now firmly established itself as a discipline in molecular biology, and encompasses a wide range of subject areas from structural biology, genomics to gene expression studies. In this text we provide an introduction and overview of the current state of the field. We discuss the main principles that underpin bioinformatics analyses, look at the types of biological information and databases that are commonly used, and finally examine some of the studies that are being conducted, particularly with reference to transcription regulatory systems. The aims of bioinformatics are threefold. First, at its simplest bioinformatics organises data in a way that allows researchers to access existing information and to submit new entries as they are produced, e.g. the Protein Data Bank for 3D macromolecular structures . While data-curation is an essential task, the information stored in these databases is essentially useless until analysed. Thus the purpose of bioinformatics extends much further. The second aim is to develop tools and resources that aid in the analysis of data. For example, having sequenced a particular protein, it is of interest to compare it with previously characterised sequences. This needs more than just a simple text-based search and programs such as FASTA and PSI-BLAST must consider what comprises a biologically significant match. Development of such resources dictates expertise in computational theory as well as a thorough understanding of biology. The third aim is to use these tools to analyse the data and interpret the results in a biologically meaningful manner. Traditionally, biological studies examined individual systems in detail, and frequently compared them with a few that are related. In bioinformatics, we can now conduct global analyses of all the available data with the aim of uncovering common principles that apply across many systems and highlight novel feature.","brand":"Arcler Education Inc","offers":[{"title":"Default Title","offer_id":49084269723991,"sku":"9781680945225","price":136.8,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781680945225.jpg?v=1725551607"}],"url":"https:\/\/bookcurl.com\/collections\/molecular-biology.oembed?page=11","provider":"Book Curl","version":"1.0","type":"link"}