{"title":"Metabolism Books","description":"","products":[{"product_id":"enzymes-9780198824985","title":"Enzymes","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eEnzymes are the astonishing, tiny molecular machines that make life possible. Each one of these small proteins speeds up a single chemical reaction inside a living organism many millionfold. Working together, teams of enzymes carry out all the processes that collectively we recognise as life, from making DNA to digesting food. This Very Short Introduction explains the why and the how of speeding up these reactions - catalysis - before going on to reveal how we have evolved these catalysts of such extraordinary power and exquisite selectivity. Paul Engel shows how X-ray crystallography has revealed the complex molecular shapes that allow enzymes to function at an extraordinarily sophisticated level. He also examines medical aspects of enzymes, both in the way faulty enzymes cause disease and in the way enzymes can be used for diagnosis and therapy. Finally, he looks at the many varied ways in which individual enzymes, taken out of their biological context, are used nowadays as tools - in washing powders, food production, waste treatment, and chemical synthesis.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eA fairly comprehensive textbook that provides a decent technical grounding in enzymology and will no doubt teach many professional biologists a thing or two * Nadia Abbott AMRSB, The Biologist *\u003cbr\u003eThis book would be an excellent accompaniment to an undergraduate biology student or someone with a scientific background who wishes to know more about enzymology. * Lucy Elphick, The Biochemist  *\u003cbr\u003eIt would be perfect for students who want to have a (somewhat more than) basic understanding of the subject before delving deeper ... my overall understanding of the subject is more rounded. Thanks Professor Engel! * Mary Staunton, University College Dublin Today *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: No Enzymes, No Life 2: Making Things Happen - Catalysis 3: The Chemical Nature of Enzymes 4: Structure for Catalysis 5: Enzymes in Action 6: Metabolic Pathways and Enzyme Evolution 7: Enzymes and Disease 8: Enzymes as Tools 9: Enzymes and Genes - New Horizons References Further reading Index","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732798353751,"sku":"9780198824985","price":9.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198824985.jpg?v=1719998445"},{"product_id":"greenspans-basic-and-clinical-endocrinology-tenth-edition-9781259589287","title":"Greenspans Basic and Clinical Endocrinology Tenth","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003ch4\u003e\u003cstrong\u003eA full-color guide to the entire field of clinical endocrinology and its scientific underpinnings â updated with the latest breakthroughs and developments\u003c\/strong\u003e\u003c\/h4\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eA Doodyâs Core Title for 2022! \u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003eGreenspanâs Basic \u0026amp; Clinical Endocrinology\u003c\/em\u003e delivers a succinct, leading-edge overview of the underlying molecular biology of the endocrine system and the latest perspectives on the diagnosis and treatment of specific diseases and disorders. Featuring an enhanced design that includes hundreds of full-color illustrations and clinical photographs, \u003cem\u003eGreenspanâs\u003c\/em\u003e is a true must-have during traditional or integrated courses in endocrinology, endocrinology rotation, or exam prep in internal medicine and endocrinology and as reference for disease management.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eGreenspanâs\u003c\/em\u003e provides clinically relevant coverage of metabolic bone disease, pancreatic hormones and diabetes mellitus, hypoglycemia, obesity, geriatric endoc\u003c\/p\u003e","brand":"McGraw-Hill Education","offers":[{"title":"Default Title","offer_id":48738458534231,"sku":"9781259589287","price":999.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781259589287.jpg?v=1723812068"},{"product_id":"good-energy-9780008604257","title":"Good Energy","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eTHE NUMBER ONE NEW YORK TIMES BESTSELLER''The best deep dive into the diseases that plague us all today, and what to do to heal.'' Jessie Inchauspe, The Glucose Goddess''A powerful vision for a brighter future  for both people and the planet.'' Jay Shetty''A tour de force'' Dr Mark HymanFix your metabolism to feel better today and prevent disease tomorrow. A bold new vision for optimizing our health now and for the future.What if depression, anxiety, infertility, insomnia, heart disease, type 2 diabetes, Alzheimer's, dementia, cancer and many other health conditions actually have the same root cause?Our ability to prevent and reverse these conditions  and feel incredible today  is under our control and simpler than we think. The key is our metabolic function  the most important and least understood factor in our overall health. As Dr Casey Means explains in this groundbreaking book, nearly every health problem we face can be explained by how well the cells in our body create and use en","brand":"HarperCollins Publishers","offers":[{"title":"Default Title","offer_id":48861574168919,"sku":"9780008604257","price":17.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780008604257.jpg?v=1722247333"},{"product_id":"5-appetites-eat-like-the-animals-for-a-naturally-healthy-diet-9780008359256","title":"5 Appetites Eat Like the Animals for a Naturally","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eA New Scientist Best Book of 2020How is it that a baboon and a blob of slime mould instinctively know what to eat for optimal health, balancing their protein, fat and carb intake in perfect proportions?In new, groundbreaking research that is transforming our understanding of nutrition, animals from locusts to lions and yes, humans too, demonstrate the remarkable science behind appetite.Appetite communicates the body''s nutritional needs to the brain, and eating in accordance with your body''s demands, like the animals, should ensure optimal health, but the modern fast food world wreaks havoc on this evolutionarily honed system.In several landmark studies, Raubenheimer and Simpson prove that appetite can be hacked  we can eat for optimal health, for increased fertility or for a longer lifespan. Understanding the science of the appetite offers tremendous power in shaping our bodies and controlling our lives.** Previously published as Eat Like the Animals **\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePraise for The Five Appetites\u003cbr\u003e‘Raubenheimer and Simpson are known for their deep knowledge of biology and its application to areas of nutrition that are of exceptional interest these days: evolution, feeding behavior, proteins, and insects. These, they weave together into a compelling narrative that should fascinate readers concerned about the science of what we eat as well as the influence of our food environment on our biology.’ Marion Nestle, author of What to Eat\u003c\/p\u003e           \u003cp\u003ePraise for David Raubenheimer and Stephen J. Simpson\u003cbr\u003e‘This outstanding book provides the first comprehensive theoretical framework for analyzing the roles of nutrition across a huge swath of fields, from ecology and evolution to conservation and human health. The Nature of Nutrition is creative and scholarly yet approachable. I know of no other book like it.’ Bernard J. Crespi, Simon Fraser University\u003c\/p\u003e           \u003cp\u003e‘Strikingly well-written … The clear language and enlightening examples allow for the educated layman interested in biology to be astonished by the enormous implications of the nature of nutrition.’ American Journal of Human Biology\u003c\/p\u003e           \u003cp\u003e‘A really good read.’ Bulletin of the British Ecological Society\u003c\/p\u003e","brand":"HarperCollins Publishers","offers":[{"title":"Default Title","offer_id":48863958303063,"sku":"9780008359256","price":9.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780008359256.jpg?v=1722269772"},{"product_id":"precision-medicine-in-neurodegenerative-disorders-9780323855556","title":"Precision Medicine in Neurodegenerative Disorders","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart 3 Basic Science Development 1. Role of rodent models in advancing precision medicine for Parkinson disease 2. The allure and pitfalls of the prion-like aggregation in neurodegeneration 3. The shift to a proteinopenia paradigm in neurodegeneration 4. Disease mechanisms as subtypes: Lysosomal dysfunction in the endolysosomal Parkinson disease subtype 5. Disease mechanisms as subtypes: Mitochondrial and bioenergetic dysfunction  6. Disease mechanisms as subtypes: Immune dysfunction in Parkinson disease 7. Disease mechanisms as subtypes: Inflammation in Parkinson disease and related disorders 8. Disease mechanisms as subtypes: Microbiome  9. LRRK2: Genetic mechanisms vs genetic subtypes  10. Genetic mechanism vs genetic subtypes: The example of GBA  11. Subtyping monogenic disorders: Huntington disease    Part 4 Clinical Trials and Therapeutic Approaches 12. Disease-modifying vs symptomatic treatments: splitting over lumping 13. Restorative cell and gene therapies for Parkinson disease 14. The promise and challenges of extracellular vesicles in the diagnosis of neurodegenerative diseases 15. Therapeutic potential of extracellular vesicles in neurodegenerative disorders 16. Lessons from antiamyloid-ß immunotherapies in Alzheimer disease  17. Lessons from immunotherapies in multiple sclerosis  18. Adaptive clinical trials and master protocols 19. Role of novel endpoints and evaluations of response in Parkinson Disease 20. Leveraging the regulatory framework to facilitate drug development in Parkinson disease","brand":"Elsevier - Health Sciences Division","offers":[{"title":"Default Title","offer_id":48864431472983,"sku":"9780323855556","price":193.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780323855556.jpg?v=1722271912"},{"product_id":"metabolism-at-a-glance-9780470674710","title":"Metabolism at a Glance","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eMetabolism at a Glance presents a concise, illustrated summary of metabolism in health and disease. This essential text is progressively appropriate for introductory through to advanced medical and biochemistry courses.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eAcknowledgements x\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 1 Energy metabolism\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Introduction to metabolic pathways 2\u003c\/p\u003e \u003cp\u003e2 Biosynthesis of ATP I: ATP, the molecule that powers metabolism 4\u003c\/p\u003e \u003cp\u003e3 Biosynthesis of ATP II: mitochondrial respiratory chain 6\u003c\/p\u003e \u003cp\u003e4 Oxidation of cytosolic NADH: the malate\/aspartate shuttle and glycerol phosphate shuttle 8\u003c\/p\u003e \u003cp\u003e5 Metabolism of glucose to provide energy 10\u003c\/p\u003e \u003cp\u003e6 Metabolism of one molecule of glucose yields 31 (or should it be 38?) molecules of ATP 12\u003c\/p\u003e \u003cp\u003e7 Anaerobic metabolism of glucose and glycogen to yield energy as ATP 14\u003c\/p\u003e \u003cp\u003e8 2,3‐Bisphosphoglycerate (2,3‐BPG) and the red blood cell 16\u003c\/p\u003e \u003cp\u003e9 Metabolism of triacylglycerol to provide energy as ATP 18\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 2 Carbohydrate metabolism\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10 Metabolism of glucose to glycogen 20\u003c\/p\u003e \u003cp\u003e11 Glycogen metabolism I 22\u003c\/p\u003e \u003cp\u003e12 Glycogen metabolism II 24\u003c\/p\u003e \u003cp\u003e13 Glycogen metabolism III: regulation of glycogen breakdown (glycogenolysis) 26\u003c\/p\u003e \u003cp\u003e14 Glycogen metabolism IV: regulation of glycogen synthesis (glycogenesis) 28\u003c\/p\u003e \u003cp\u003e15 Pentose phosphate pathway: the production of NADPH and reduced glutathione 30\u003c\/p\u003e \u003cp\u003e16 Regulation of glycolysis: overview exemplified by glycolysis in cardiac muscle 32\u003c\/p\u003e \u003cp\u003e17 Glycolysis in skeletal muscle: biochemistry of sport and exercise 34\u003c\/p\u003e \u003cp\u003e18 Regulation of gluconeogenesis 36\u003c\/p\u003e \u003cp\u003e19 Regulation of Krebs cycle 38\u003c\/p\u003e \u003cp\u003e20 Mammals cannot synthesize glucose from fatty acids 40\u003c\/p\u003e \u003cp\u003e21 Supermouse: overexpression of cytosolic PEPCK in skeletal muscle causes super‐athletic performance 42\u003c\/p\u003e \u003cp\u003e22 Sorbitol, galactitol, glucuronate and xylitol 44\u003c\/p\u003e \u003cp\u003e23 Fructose metabolism 46\u003c\/p\u003e \u003cp\u003e24 Ethanol metabolism 48\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 3 Fat metabolism\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e25 Pyruvate\/malate cycle and the production of NADPH 50\u003c\/p\u003e \u003cp\u003e26 Metabolism of glucose to fat (triacylglycerol) 52\u003c\/p\u003e \u003cp\u003e27 Metabolism of glucose to fatty acids and triacylglycerol 54\u003c\/p\u003e \u003cp\u003e28 Glycolysis and the pentose phosphate pathway collaborate in liver to make fat 56\u003c\/p\u003e \u003cp\u003e29 Esterification of fatty acids to triacylglycerol in liver and white adipose tissue 58\u003c\/p\u003e \u003cp\u003e30 Mobilization of fatty acids from adipose tissue I: regulation of lipolysis 60\u003c\/p\u003e \u003cp\u003e31 Mobilization of fatty acids from adipose tissue II: triacylglycerol\/fatty acid cycle 62\u003c\/p\u003e \u003cp\u003e32 Glyceroneogenesis 64\u003c\/p\u003e \u003cp\u003e33 Metabolism of protein to fat after feeding 66\u003c\/p\u003e \u003cp\u003e34 Elongation and desaturation of fatty acids 68\u003c\/p\u003e \u003cp\u003e35 Fatty acid oxidation and the carnitine shuttle 70\u003c\/p\u003e \u003cp\u003e36 Ketone bodies 72\u003c\/p\u003e \u003cp\u003e37 Ketone body utilization 74\u003c\/p\u003e \u003cp\u003e38 β-Oxidation of unsaturated fatty acids 76\u003c\/p\u003e \u003cp\u003e39 Peroxisomal β‐oxidation 78\u003c\/p\u003e \u003cp\u003e40 α‐ and β‐oxidation 80\u003c\/p\u003e \u003cp\u003e41 ω-Oxidation 82\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 4 Steroid metabolism\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e42 Cholesterol 84\u003c\/p\u003e \u003cp\u003e43 Steroid hormones and bile salts 86\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 5 Amino acid metabolism\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e44 Biosynthesis of the non‐essential amino acids 88\u003c\/p\u003e \u003cp\u003e45 Catabolism of amino acids I 90\u003c\/p\u003e \u003cp\u003e46 Catabolism of Amino Acids II 92\u003c\/p\u003e \u003cp\u003e47 Metabolism of amino acids to glucose in starvation and during the period immediately after refeeding 94\u003c\/p\u003e \u003cp\u003e48 Disorders of amino acid metabolism 96\u003c\/p\u003e \u003cp\u003e49 Phenylalanine and tyrosine metabolism 98\u003c\/p\u003e \u003cp\u003e50 Tryptophan metabolism: the biosynthesis of NAD + , serotonin and melatonin 100\u003c\/p\u003e \u003cp\u003e51 Ornithine cycle for the production of urea: the ‘urea cycle’ 102\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 6 Metabolic channelling\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e52 Metabolic channelling I: enzymes are organized to enable channelling of metabolic intermediates 104\u003c\/p\u003e \u003cp\u003e53 Metabolic channelling II: fatty acid synthase 106\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 7 Purines, pyrimidines and porphyrins\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e54 Amino acid metabolism, folate metabolism and the ‘1‐carbon pool’ I: purine biosynthesis 108\u003c\/p\u003e \u003cp\u003e55 Amino acid metabolism, folate metabolism and the ‘1‐carbon pool’ II: pyrimidine biosynthesis 110\u003c\/p\u003e \u003cp\u003e56 Krebs uric acid cycle for the disposal of nitrogenous waste 112\u003c\/p\u003e \u003cp\u003e57 Porphyrin metabolism, haem and the bile pigments 114\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 8 Integration of metabolic pathways and diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e58 Metabolic pathways in fasting liver and their disorder in Reye’s syndrome 116\u003c\/p\u003e \u003cp\u003e59 Diabetes I: metabolic changes in diabetes 118\u003c\/p\u003e \u003cp\u003e60 Diabetes II: types I and II diabetes, MODY and pancreatic β‐cell metabolism 120\u003c\/p\u003e \u003cp\u003e61 Diabetes III: type 2 diabetes and dysfunctional liver metabolism 122\u003c\/p\u003e \u003cp\u003eIndex 125\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":48864636764503,"sku":"9780470674710","price":34.15,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470674710.jpg?v=1722272838"},{"product_id":"textbook-of-diabetes-9781119697428","title":"Textbook of Diabetes","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eTextbook of Diabetes Classic textbook providing diabetologists and endocrinologists with illustrated and clinically focused content on diabetes Now in its sixth edition, the Textbook of Diabetes has established itself as the modern, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the textbook hosts an unrivalled blend of clinical and scientific content. Written by highly experienced editors and international contributors all of whom have provided insight on new developments in diabetes care. These include the most recent guidelines from the European Association for the Study of Diabetes (EASD), the American Diabetes Association (ADA), Diabetes UK, and the National Institute for Health and Care Excellence (NICE) and information on the latest treatment modalities used around the world.  The textbook includes free access to the Wiley Digital Edition which provides easy-to-use searching across the book, the full reference list with web links, illustrations and photographs, and post-publication updates.  Sample topics covered in Textbook of Diabetes include:  Diabetes in its historical and social context, covering the history of diabetes, past classification and diagnosis of diabetes and the global burden of diabetes Normal physiology, covering glucose homeostasis, islet function and insulin secretion, and  glucagon in islet and metabolic regulation Pathogenesis of diabetes, covering genetics of diabetes and obesity, autoimmune type 1 diabetes  and other disorders with type 1 diabetes phenotype Other types of diabetes, covering endocrine disorders that cause diabetes, pancreatic diseases and diabetes and drug-induced diabetes Beautifully illustrated with a clinical focus, Textbook of Diabetes provides endocrinologists and diabetologists, both consultants\/specialists and those in training, with a fresh and comprehensive clinical resource to consult time and time again. The text is also of value to specialist diabetes nurses and researchers in the field.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of Contributors, viii\u003c\/p\u003e \u003cp\u003ePreface, xv\u003c\/p\u003e \u003cp\u003eList of Abbreviations, xvi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 1 Diabetes in its Historical and Social Context\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 The History of Diabetes Mellitus, 3\u003cbr\u003e\u003ci\u003eRobert B. Tattersall and David R. Matthews\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Classification and Diagnosis of Diabetes, 22\u003cbr\u003e\u003ci\u003eAmbady Ramachandran, Chamukuttan Snehalatha, Arun Raghavan, and Arun Nanditha\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 The Global Burden of Diabetes, 28\u003cbr\u003e\u003ci\u003eJessica L. Harding, Mary Beth Weber, and Jonathan E. Shaw\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Epidemiology of Type 1 Diabetes, 41\u003cbr\u003e\u003ci\u003eLars C. Stene and Jaakko Tuomilehto\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Epidemiology of Type 2 Diabetes, 55\u003cbr\u003e\u003ci\u003eRonald C.W. Ma and Peter C.Y. Tong\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 2 Normal Physiology\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6 Overview of Glucose Metabolism, 77\u003cbr\u003e\u003ci\u003eRichard I.G. Holt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Islet Function and Insulin Secretion, 84\u003cbr\u003e\u003ci\u003ePeter M. Jones and Shanta J. Persaud\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Glucagon in Islet and Metabolic Regulation, 99\u003cbr\u003e\u003ci\u003eJonathan E. Campbell and David A. D'Alessio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Mechanism of Insulin Action, 111\u003cbr\u003e\u003ci\u003eMorris F. White\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Central Control of Glucose Homeostasis, 128\u003cbr\u003e\u003ci\u003eKimberly M. Alonge, Kendra L. Francis, Nicole E. Richardson, and Michael W. Schwartz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Control of Body Weight: How and Why Do We Gain Weight Easier Than We Lose It?, 142\u003cbr\u003e\u003ci\u003eJanine Makaronidis and Rachel L. Batterham\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 3 Pathogenesis of Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12 The Genetics of Diabetes, 157\u003cbr\u003e\u003ci\u003eRashmi B. Prasad\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Genetics of Obesity, 197\u003cbr\u003e\u003ci\u003eI. Sadaf Farooqi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Autoimmune Type 1 Diabetes, 203\u003cbr\u003e\u003ci\u003eOmar Akel and Ake Lernmark\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Other Disorders with Type 1 Diabetes and Atypical Phenotypes, 216\u003cbr\u003e\u003ci\u003eAlice P.S. Kong, Elaine Y.K. Chow, Andrea O.Y. Luk, and Juliana C.N. Chan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Abnormalities of Insulin Secretion and β-Cell Defects in Type 2 Diabetes, 225\u003cbr\u003e\u003ci\u003eStefano Del Prato, Cristina Bianchi, and Giuseppe Daniele\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Insulin Resistance in Type 2 Diabetes, 238\u003cbr\u003e\u003ci\u003eMichael Roden, Kitt Falk Petersen, and Gerald I. Shulman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Obesity and Diabetes, 250\u003cbr\u003e\u003ci\u003eNick Finer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 The Microbiome and Diabetes, 261\u003cbr\u003e\u003ci\u003eAmanda J. Cox, Nicholas P. West, and Allan W. Cripps\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 4 Other Types of Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20 Monogenic Causes of Diabetes, 275\u003cbr\u003e\u003ci\u003eBrittany L. Resnick, Maggie H. Shepherd, and Andrew T. Hattersley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Drug-Induced Diabetes, 295\u003cbr\u003e\u003ci\u003eCharles D. Ponte and Devra K. Dang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Diabetes in Hypersecreting Endocrine Disorders, 304\u003cbr\u003e\u003ci\u003eAllan A. Vaag, Neil A. Hanley, and Caroline M. Kistorp\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Pancreatic Disease and Diabetes, 319\u003cbr\u003e\u003ci\u003eRanjit Unnikrishnan and Viswanathan Mohan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Clinical Presentations of Diabetes, 330\u003cbr\u003e\u003ci\u003eEe Lin Lim and Roy Taylor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 5 Managing the Person with Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e25 The Aims of Diabetes Care, 343\u003cbr\u003e\u003ci\u003eKatharine D. Barnard-Kelly and Richard I.G. Holt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Education to Empower the Person with Diabetes, 354\u003cbr\u003e\u003ci\u003eIngrid Willaing and Michael Vallis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Dietary Management of Diabetes, 368\u003cbr\u003e\u003ci\u003eNicola Guess\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Physical Activities and Diabetes, 382\u003cbr\u003e\u003ci\u003eEmma J. Cockcroft and Robert C. Andrews\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Monitoring Diabetes, 404\u003cbr\u003e\u003ci\u003eEmma English\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Biomarkers and Precision Medicine in Diabetes, 414\u003cbr\u003e\u003ci\u003eSok Cin Tye, Michele Provenzano, and Hiddo J.L. Heerspink\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 6 Treatment of Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e31 Insulin and Insulin Treatment, 431\u003cbr\u003e\u003ci\u003eRoman Vangoitsenhoven, Parth Narendran, and Chantal Mathieu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 New Technologies for Glucose Monitoring, 444\u003cbr\u003e\u003ci\u003eThomas Danne and Olga Kordonouri\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 New Technologies for Insulin Administration, 459\u003cbr\u003e\u003ci\u003eHannah Forde and Pratik Choudhary\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Whole Pancreas and Islet Cell Transplantation, 473\u003cbr\u003e\u003ci\u003eBraulio A. Marfil-Garza, Peter A. Senior, and A.M. James Shapiro\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Oral Glucose-Lowering Agents, 492\u003cbr\u003e\u003ci\u003eClifford J. Bailey and Andrew J. Krentz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e36 Non-insulin Parenteral Therapies, 520\u003cbr\u003e\u003ci\u003eTina Vilsboll, Mikkel Christensen, Andreas Andersen, and Filip K. Knop\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e37 How to Use Type 2 Diabetes Treatments in Clinical Practice, 534\u003cbr\u003e\u003ci\u003eThomas Karagiannis, Aris Liakos, and Apostolos Tsapas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e38 Weight Management and Metabolic Surgery, 551\u003cbr\u003e\u003ci\u003eAlexis Sudlow, Dimitri J. Pournaras, and Carel W. le Roux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e39 In-Hospital Treatment and Surgery in People with Diabetes, 559\u003cbr\u003e\u003ci\u003eKetan Dhatariya, Philip Newland-Jones, and Mayank Patel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e40 Hypoglycaemia in Diabetes, 579\u003cbr\u003e\u003ci\u003eAhmed Iqbal, Elaine Y.K. Chow, Timothy W. Jones, and Simon R. Heller\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e41 Acute Metabolic Complications of Diabetes: Diabetic Ketoacidosis and the Hyperosmolar Hyperglycaemic State in Adults, 602\u003cbr\u003e\u003ci\u003ePhilip Newland-Jones, Mayank Patel, and Ketan Dhatariya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 7 Microvascular Complications in Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e42 Pathogenesis of Microvascular Complications, 615\u003cbr\u003e\u003ci\u003eAllan Flyvbjerg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e43 Diabetic Retinopathy, 629\u003cbr\u003e\u003ci\u003eToke Bek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e44 Diabetic Nephropathy, 640\u003cbr\u003e\u003ci\u003ePeter Rossing and Allan Flyvbjerg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e45 Diabetic Neuropathy, 655\u003cbr\u003e\u003ci\u003eShazli Azmi, Uazman Alam, and Rayaz A. Malik\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 8 Macrovascular Complications in Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e46 Pathogenesis of Macrovascular Complications in Diabetes, 681\u003cbr\u003e\u003ci\u003eJakob A. Ostergaard, Tomasz J. Block, Sophia Dahm, Waheed Khan, and Karin A.M. Jandeleit-Dahm\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e47 Hypertension and Diabetes, 700\u003cbr\u003e\u003ci\u003ePeter M. Nilsson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e48 Dyslipidaemia and Diabetes, 713\u003cbr\u003e\u003ci\u003eAdie Viljoen, Ahmed Handhle, and Anthony S. Wierzbicki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e49 Ischaemic Heart Disease in Diabetes, 724\u003cbr\u003e\u003ci\u003eMichael Lehrke and Nikolaus Marx\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e50 Heart Failure and Diabetes, 732\u003cbr\u003e\u003ci\u003eAmbarish Pandey, Kershaw V. Patel, and Subodh Verma\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e51 Cerebrovascular Disease and Diabetes, 745\u003cbr\u003e\u003ci\u003eColum F. Amory, Jesse Weinberger, and Travis S. Smith\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e52 Peripheral Vascular Disease, 755\u003cbr\u003e\u003ci\u003eHenrik H. Sillesen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 9 Other Complications of Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e53 Foot Problems in People with Diabetes, 771\u003cbr\u003e\u003ci\u003eFrank L. Bowling, Keeley J. Foley, and Andrew J.M. Boulton\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e54 Sexual Function in Men and Women with Diabetes, 780\u003cbr\u003e\u003ci\u003eKirsty Winkley, Camilla Kristensen, Jackie Fosbury, and David Price\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e55 Gastrointestinal Manifestations of Diabetes, 796\u003cbr\u003e\u003ci\u003eMichael Camilleri and Adil E. Bharucha\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e56 Diabetes and Oral Health, 810\u003cbr\u003e\u003ci\u003ePalle Holmstrup, Christian Damgaard, and Allan Flyvbjerg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e57 Diabetes and Non-alcoholic Fatty Liver Disease, 820\u003cbr\u003e\u003ci\u003eAlessandro Mantovani, Giovanni Targher, and Christopher D. Byrne\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e58 The Skin in Diabetes, 838\u003cbr\u003e\u003ci\u003ePaul Devakar Yesudian\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e59 Bone and Rheumatic Disorders in Diabetes, 853\u003cbr\u003e\u003ci\u003eAndrew Grey and Nicola Dalbeth\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e60 Diabetes and Cancer: Risk, Outcomes, and Clinical Implications, 867\u003cbr\u003e\u003ci\u003eEllena Badrick, Emily J. Gallagher, and Andrew G. Renehan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e61 Diabetes and Infections, 878\u003cbr\u003e\u003ci\u003eAndrea O.Y. Luk and Clive S. Cockram\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e62 Sleep and Diabetes, 897\u003cbr\u003e\u003ci\u003eSonya Deschênes, Amy McInerney, and Norbert Schmitz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 10 Psychosocial Aspects of Diabetes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e63 Psychosocial and Behavioural Aspects of Diabetes, 907\u003cbr\u003e\u003ci\u003eFrans Pouwer and Jane Speight\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e64 Role of Cognitive Function in Managing People with Diabetes, 922\u003cbr\u003e\u003ci\u003eTamsin Santos, Chelsea Baird, Sally Eastwood, Kerrie Shiell, and Joseph E. Ibrahim\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e65 Mental Disorders and Diabetes, 933\u003cbr\u003e\u003ci\u003eNajma Siddiqi, Marietta Stadler, and Richard I.G. Holt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e66 Social Aspects of Diabetes, 956\u003cbr\u003e\u003ci\u003eBrian M. Frier and Mark W.J. Strachan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e67 Social Determinants of Diabetes, 973\u003cbr\u003e\u003ci\u003eKeri F. Kirk, Gerald McKinley, Briana Mezuk, and Erica Spears\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 11 Diabetes in Special Groups\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e68 Ethnic, Cultural, and Religious Aspects to the Management of Diabetes, 987\u003cbr\u003e\u003ci\u003eWasim Hanif, Sarah N. Ali, and Vinod Patel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e69 Diabetes in Childhood, 999\u003cbr\u003e\u003ci\u003eJennifer M. Ikle, Ananta Addala, and David M. Maahs\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e70 Adolescence and Emerging Adulthood: Diabetesin Transition, 1019\u003cbr\u003e\u003ci\u003eCharlotte W. Chen and Lori M.B. Laffel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e71 Diabetes in Pregnancy, 1034\u003cbr\u003e\u003ci\u003eDavid R. McCance and Laura Cassidy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e72 Diabetes in Old Age, 1072\u003cbr\u003e\u003ci\u003eAhmed H. Abdelhafiz and Alan J. Sinclair\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e73 Diabetes at the End of Life, 1085\u003cbr\u003e\u003ci\u003eTrisha Dunning and June James\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 12 Delivery and Organization of Diabetes Care\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e74 The Role of the Multidisciplinary Team across Primary and Secondary Care, 1097\u003cbr\u003e\u003ci\u003eSamuel Seidu and Kamlesh Khunti\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e75 Models of Diabetes Care in Low-and Middle-Income Countries, 1107\u003cbr\u003e\u003ci\u003eDavid Beran, Sigiriya Aebischer Perone, and Maria Lazo-Porras\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart 13 Future Directions\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e76 Immunotherapies for Type 1 Diabetes, 1125\u003cbr\u003e\u003ci\u003eJesper Johannesen and Flemming Pociot\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e77 Stem Cell Therapy in Diabetes, 1137\u003cbr\u003e\u003ci\u003eAngelo Avogaro and Gian Paolo Fadini\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e78 Gene Therapy for Diabetes, 1144\u003cbr\u003e\u003ci\u003eVeronica Jimenez and Fatima Bosch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e79 Future Drug Treatments for Type 2 Diabetes, 1154\u003cbr\u003e\u003ci\u003eClifford J. Bailey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex, 1167\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":48866411807063,"sku":"9781119697428","price":193.46,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119697428.jpg?v=1722278515"},{"product_id":"neurochemistry-of-metabolic-diseases-lysosomal-storage-diseases-phenylketonuria-and-canavan-disease-9781536183399","title":"Neurochemistry of Metabolic Diseases: Lysosomal","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eMetabolic disorder caused by altered levels of metabolism resulting pathophysiological abnormalities often leads to childhood death. Several new developments on metabolic diseases research have been emerging. Gaucher disease is a lysosomal storage disorder caused by glucocerebrosidase gene mutations resulting glucocerebrosidase deficiency. Current studies show that the same gene mutations also contribute to the Parkinson''s disease. Tetrahydrobiopterin (BH4) has been widely used in treating patients with Phenylketonuria over a decade. Recent studies reveal that patients treated with BH4 over one-year period showed reduced levels of serum B12, folate and iron intake and therefore patients under chronic BH4 treatment needed to be advised to have additional micronutrients along with BH4. Macrocephaly was used as one of the important features to diagnose Canavan disease. However, a recent study showing a child with aspartoacylase gene mutation developed microcephaly. Hence, Canavan disease phenotype can be either macrocephaly or microcephaly. These are a few examples of recent developments on metabolic diseases research. Therefore, this book was aimed to compose current developments on metabolic diseases research for the use by broad spectrum of experts including Physicians, Neuroscientists, Neurologists, Biomedical researchers, Biochemists, Molecular biologists, Basic Science Researchers and Medical Students.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886180905303,"sku":"9781536183399","price":163.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781536183399.jpg?v=1722539111"},{"product_id":"progress-in-metabolic-syndrome-research-9781600211799","title":"Progress in Metabolic Syndrome Research","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSince cardiovascular (heart and blood vessel) disease is the leading cause of death for adults in developed countries, many medical studies focus on treating or preventing heart disease and stroke. The metabolic syndrome, a collection of unhealthy body measurements and abnormal laboratory test results, may identify persons at high risk for developing cardiovascular disease. Aggressive lifestyle modification and possible use of medications to treat the conditions that make up the metabolic syndrome may reduce a person''s chances of developing heart disease or stroke. The metabolic syndrome has also been called syndrome X or insulin resistance syndrome.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886587359575,"sku":"9781600211799","price":173.24,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781600211799.jpg?v=1722540752"},{"product_id":"enterovirus-infections-type-1-diabetes-mellitus-9781600213397","title":"Enterovirus Infections \u0026 Type 1 Diabetes Mellitus","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eEnteroviruses have been examined for their possible role in the etiology of type 1 diabetes for nearly 40 years. It is now evident from studies in several countries that enterovirus infection accompanies or precedes the onset of diabetes in many individuals. These evidences include the isolation of coxsackievirus B4 from the pancreas of a child at diagnosis of type 1 diabetes, several epidemiological and prospective studies showing that some cases of type 1 diabetes are strongly associated with enterovirus infections, seasonal incidence studies, case-control studies that show an increased prevalence and levels of IgM antibodies to enterovirus in newly diagnosed patients. Other evidences involves several case studies in which diabetes develops after an enterovirus infections, increased T cell response to enterovirus antigens in type 1 diabetic patients, suggestions that enterovirus infections during pregnancy might initiate the events leading to childhood diabetes, and a higher frequency of enterovirus RNA in the serum\/blood of type 1 diabetic patients at diagnosis. This book Provides a better understanding of enteroviral biology and the potential alternative pathogenic mechanisms through which enteroviruses may cause diabetes.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886592799063,"sku":"9781600213397","price":129.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781600213397.jpg?v=1722540771"},{"product_id":"insulin-resistance-symptoms-causes-treatment-9781608768295","title":"Insulin Resistance: Symptoms, Causes \u0026 Treatment","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eInsulin resistance (IR) and elevated blood pressure are two key features of the metabolic syndrome, which play an important role in the development of secondary cardiovascular complications. In this book, the effects of insulin resistance on the various vasoactive pathways are explored, which affect the equilibrium between vascular relaxation and constriction. Furthermore, the interaction between oestrogen, testosterone and insulin signalling-dependent changes in vascular reactivity and blood pressure are discussed. Also addressed in this book are the mechanisms underlying reciprocal relationships between insulin secretion, insulin resistance and inflammation in the pathological state and in its subsequent improvement. Moreover, the current concepts in understanding the underlying risk factors contributing to insulin resistance are examined, focusing on the role of magnesium deficiency that emerges as potential pathogenic key related with decreasing insulin sensitivity. In addition, it is widely accepted that metabolic syndrome is related to cardiovascular disease and that insulin resistance is one of the causes of metabolic syndrome. The authors discuss thiazolidinediones (TZDs), a class of antidiabetes agents, as a means to improve endothelial dysfunction, prevent atherosclerosis, and significantly reduce the risk of cardiovascular disease.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886770237783,"sku":"9781608768295","price":185.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781608768295.jpg?v=1722541484"},{"product_id":"neurochemistry-of-metabolic-diseases-lysosomal-storage-diseases-phenylketonuria-canavan-disease-9781612096711","title":"Neurochemistry of Metabolic Diseases: Lysosomal","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886822797655,"sku":"9781612096711","price":146.24,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781612096711.jpg?v=1722541732"},{"product_id":"computational-metabolomics-9781617616082","title":"Computational Metabolomics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886916874583,"sku":"9781617616082","price":67.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781617616082.jpg?v=1722542159"},{"product_id":"advances-in-diagnosis-management-of-glycogenosis-ii-9781621005155","title":"Advances in Diagnosis \u0026 Management of","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe literature concerning muscle Glycogenoses reflects a world-wide interest which has been greatly intensified, mainly over the last ten years. To a large extent, this renewed interest is due to recent advances in diagnosing and treating the Lysosomal disease named Glycogenosis II or Pompe disease (GSD II). The new therapeutic approaches must induce us to make a great effort in order to better diagnose, treat and follow correctly the patients with Pompe disease. This book is a comprehensive text which covers all of the aspects regarding this disease, from pathogenic to clinical and therapeutic features.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886974939479,"sku":"9781621005155","price":106.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781621005155.jpg?v=1722542431"},{"product_id":"parathyroid-anatomy-functions-disorders-9781621007654","title":"Parathyroid: Anatomy, Functions \u0026 Disorders","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book follows an up to date authoritative style on the subject of parathyroid glands and their disorder. This book seeks to expand the horizon of parathyroid hormone use and provides in depth information on surgical techniques for managing its disorder. There are four sections on anatomy, function, disorder and treatment. The first three show how these areas are interconnected and the fourth on techniques for managing parathyroid disease. While short enough to be read as a treatise on parathyroid glands it is also authoritative enough to be used as a reference text.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886978216279,"sku":"9781621007654","price":149.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781621007654.jpg?v=1722542448"},{"product_id":"advances-in-diagnosis-management-of-glycogenosis-ii-9781626184640","title":"Advances in Diagnosis \u0026 Management of","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe literature concerning muscle Glycogenoses reflects a world-wide interest which has been greatly intensified, mainly over the last ten years. To a large extent, this renewed interest is due to recent advances in diagnosing and treating the Lysosomal disease named Glycogenosis II or Pompe disease (GSD II). The new therapeutic approaches must induce us to make a great effort in order to better diagnose, treat and follow correctly the patients with Pompe disease. This book is a comprehensive text which covers all of the aspects regarding this disease, from pathogenic to clinical and therapeutic features.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48887042343255,"sku":"9781626184640","price":67.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781626184640.jpg?v=1722542729"},{"product_id":"glucose-uptake-regulation-signaling-pathways-health-implications-9781626186705","title":"Glucose Uptake: Regulation, Signaling Pathways \u0026","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eInsulin stimulates the uptake of glucose in several target tissues, including skeletal muscle and adipose tissue, thereby contributing to the decline in the blood glucose level. In this book, the authors present current research in the study of the regulation, signalling pathways and health implications of glucose uptake. Topics include glucose uptake and transport regulation; the mechanisms that contribute to glucose homeostasis; expression and regulation of neuronal glucose transporters in health and disease; role for the microvasculature in glucose uptake in skeletal muscle; implications of diabetes on sperm glucose uptake and metabolism; the beneficial role of estrogen signalling in glucose homeostasis and energy expenditure; glucose uptake and androgen responsiveness of prostate cancer cells; regulation of intestinal glucose uptake by leptin; and the Ras superfamily of small GTP-binding proteins in glucose transporter type 4-mediated glucose uptake in insulin-responsive tissues.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48887045914967,"sku":"9781626186705","price":159.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781626186705.jpg?v=1722542745"},{"product_id":"understanding-metabolic-syndrome-paper-poster-9781932922271","title":"Understanding Metabolic Syndrome Paper Poster","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.","brand":"Scientific Publishing","offers":[{"title":"Default Title","offer_id":48888761745751,"sku":"9781932922271","price":14.59,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781932922271.jpg?v=1722551010"},{"product_id":"understanding-metabolic-syndrome-laminated-poster-9781932922264","title":"Understanding Metabolic Syndrome Laminated Poster","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Scientific Publishing","offers":[{"title":"Default Title","offer_id":48888761844055,"sku":"9781932922264","price":145.14,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781932922264.jpg?v=1722551011"},{"product_id":"dietary-fibre-mechanisms-of-action-in-human-physiology-metabolism-9782742000968","title":"Dietary Fibre: Mechanisms of Action in Human","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSince the birth of the dietary fibre hypothesis in the early 1970''s, research on this topic has been growing rapidly. However, though the remarkable number of experimental works, the role of fibre on human health is still uncompletely understood. The objective of this book is to synthesise the current knowledge on the physiological effects of dietary fibre in man by focusing on the mechanisms of action.","brand":"John Libbey Eurotext","offers":[{"title":"Default Title","offer_id":48888987320663,"sku":"9782742000968","price":17.09,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9782742000968.jpg?v=1722552134"},{"product_id":"lysosomal-storage-diseases-early-diagnosis-new-treatments-9782742007790","title":"Lysosomal Storage Diseases: Early Diagnosis \u0026 New","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"John Libbey Eurotext","offers":[{"title":"Default Title","offer_id":48888990531927,"sku":"9782742007790","price":53.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9782742007790.jpg?v=1722552148"},{"product_id":"atlas-of-clinical-endocrinology-and-metabolism-9780367608354","title":"Atlas of Clinical Endocrinology and Metabolism","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eThis updated text is a pictorial atlas of endocrine and metabolic disorders. Each chapter focuses on providing multiple illustrations as well as a thorough discussion of the diagnosis and management of a variety of endocrine diseases with their appropriate treatment plans. Using updated guidelines, it provides a comprehensive discussion of the latest therapies, including diabetes technology. Presenting a large number of clinical images, including imaging of thyroid ultrasounds, DXA images, bone scans, and new technologies in diabetes mellitus, this atlas aims to provide the reader with the information needed to make accurate diagnoses, making it an updated source of highly illustrated information for endocrinologists, clinicians, residents, fellows and trainees. With new chapters on transgender medicine and obesity, this textbook is a valuable resource for the contemporary endocrine practitioner.\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFeatures new chapters such as transgender medicine and inborn errors of meta\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Thyroid Disorders. 2. Diabetes Mellitus. 3.\tObesity. 4. Metabolic Bone Disorders. 5. Hypothalamic-pituitary Disorders. 6. Adrenal Disorders. 7. Female Reproductive Disorders. 8. Male Reproductive Disorders. 9. Lipid Disorders. 10. Errors of Inborn Metabolism. 11. Neuroendocrine Tumors. 12. Endocrinologic Care of Transgender Patients. 13. Genetic Endocrine Disorders.\u003c\/li\u003e\u003c\/ul\u003e","brand":"Taylor \u0026 Francis Ltd","offers":[{"title":"Default Title","offer_id":49371697021271,"sku":"9780367608354","price":137.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780367608354.jpg?v=1730154227"},{"product_id":"goodmans-basic-medical-endocrinology-9780128158449","title":"Goodmans Basic Medical Endocrinology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"This book is a good refresher for budding endocrinologists in training or even primary care physicians\/specialists. I enjoyed reading it. This edition, published 13 years after the previous edition, is more reader-friendly with lots of references and figures. The website lets readers access the book on the go, a need of the hour of medical professionals today.\" --© Doody’s Review Service, 2021, Deepika Arvind Panday, MD, reviewer, expert opinion   \"Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study.\" --Anticancer Research   Praise for previous editions: \"...provides a solid overview of endocrine function and control...an introductory text that provides a solid basis of background information for the aspiring clinician, or for students planning to progress in a direction that investigates a broader range of organisms.\" --GENERAL AND COMPARATIVE ENDOCRINOLOGY   \"...presents the subject of human endocrinology in a way that actually makes the reader want more...this is an outstanding text for medical students, graduate students, and researchers who need a good reference book in the field.\" --LIFE SCIENCE BOOK REVIEW\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Introduction  2. Pituitary gland  3. Thyroid gland  4. The adrenal glands  5. Principles of hormone integration  6. Hormones of the gastrointestinal tract  7. The pancreatic islets   8. Hormonal regulation of fuel metabolism  9. Regulation of salt and water balance  10. Hormonal regulation of calcium balance 11. Hormonal control of growth  12. Hormonal control of reproduction in the male  13. Hormonal control of reproduction in the female: the menstrual cycle 14. Hormonal control of pregnancy and lactation","brand":"Elsevier Science Publishing Co Inc","offers":[{"title":"Default Title","offer_id":49399836967255,"sku":"9780128158449","price":112.13,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780128158449.jpg?v=1730468867"},{"product_id":"brain-and-crime-9780128213759","title":"Brain and Crime","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSection I. Introduction  1. Introduction: On brain and crime   Section II. Structure and Function 2. Genetics and epigenetics of human aggression 3. Network localization of antisocial behavior in neurological patients: Evidence and implications  4. Prison and the brain 5. Forensically relevant challenging behaviours and the genetics domain 6. Social-affective functioning and learning in psychopathy 7. Amygdala connectivity and ggression 8. The \"(a)moral brain\": When things go wrong   Section III. Brain dysfunction 9. Illicit drug use and violence  10. Child maltreatment and victimization 11. Sexual offenses and the brain 12. The risk of criminal behavior in the elderly and patients with neurodegenerative disease 13. Fetal alcohol spectrum disorders and the risk of crime   Section IV. Assessment and Treatment 14. Cognition, criminal conduct, and virtual reality: Understanding and reducing offending using simulated environments 15. Added value of neurotechnology for forensic psychiatric and psychological assessment   Section V. Ethics and Law 16. Neurolaw: Challenges and limits 17. Why neuroscience changes some things but not everything for the law 18. Neurotechnology to reduce recidivism: Ethical and legal challenges","brand":"Elsevier Science Publishing Co Inc","offers":[{"title":"Default Title","offer_id":49399839359319,"sku":"9780128213759","price":193.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780128213759.jpg?v=1730468877"},{"product_id":"mitochondrial-diseases-9780128217511","title":"Mitochondrial Diseases","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSection I. Introduction to Mitochondrial Diseases  1. Mitochondrial disease in neurology – Past, present, and future   Section II. Most Common Neurological Manifestations of Mitochondrial Disease 2. Progressive external ophthalmoplegia 3. Mitochondrial optic neuropathies 4. Leigh syndrome 5. Stroke-like episodes in adult mitochondrial disease 6. Ataxia and spastic paraplegia in mitochondrial disease 7. Peripheral neuropathy in mitochondrial disease 8. Complex neurological and multisystem presentations in mitochondrial disease   Section III. Diagnosing Mitochondrial Disease 9. Investigation of oxidative phosphorylation activity and composition in mitochondrial disease 10. Genetics of mitochondrial diseases: Current approaches for the molecular diagnosis 11. Laboratory and metabolic investigations 12. Neuroimaging in mitochondrial disease   Section IV. Therapy and Future Challenges 13. Currently available therapies in mitochondrial disease 14. Reproductive options in mitochondrial disease 15. Clinical trials in mitochondrial disease 16. Blood biomarkers of mitochondrial disease – One for all or all for one? 17. Experimental therapy for mitochondrial diseases","brand":"Elsevier Science Publishing Co Inc","offers":[{"title":"Default Title","offer_id":49399839457623,"sku":"9780128217511","price":193.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780128217511.jpg?v=1730468877"},{"product_id":"estrogen-matters-9780316578905","title":"Estrogen Matters","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Little Brown and Company","offers":[{"title":"Default Title","offer_id":49401721389399,"sku":"9780316578905","price":21.1,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780316578905.jpg?v=1730478327"},{"product_id":"endocrine-emergencies-9780323760973","title":"Endocrine Emergencies","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eDoody's Core Titles® 2022    Doody's Core Titles® 2022 Essential Purchase   \"This is a high-quality book that will be an essential reference for practitioners in a variety of fields. Clarity of writing and completeness of detail, as well as the focus on emergency situations, make it a unique resource.\" ©Doody's Review Service, 2022, Carol Scott-Conner, MD, PhD, MBA (University of Iowa Hospitals and Clinics)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eI. Thyroid    1. Thyroid storm: acute thyrotoxicosis   Trevor E. Angell and Melissa G. Lechner   2. Amiodarone induced thyrotoxicosis   Anupam Kotwal and Marius Stan   3. Ocular emergencies in Graves' ophthalmopathy   Ann Tran and Michael Kazim   4. Myxedema coma    Dorina Ylli and Leonard Wartofsky   5. Acute Suppurative Thyroiditis   Sara Ahmadi and Erik K. Alexander   6. Thyrotoxic periodic paralysis: a review and suggestions for treatment   Svetlana L. Krasnova, Jan Calissendorff and Henrik Falhammar   II. Postoperative thyroid surgical emergencies    7. Recurrent laryngeal nerve paralysis - management of the recurrent laryngeal nerve injuries    Yasuhiro Ito, Akira Miyauchi and Hiroo Masuoka   8. Post thyroidectomy emergencies: management of tracheal and esophageal injuries   Gustavo Romero-Velez and Randall P. Owen   9. Radioactive Iodine (131I) Thyroid Ablation and the Salivary Glands   Louis Mandel   III. Parathyroid    10. Hypercalcemic crisis   Tariq Chukir, Azeez Farooki and John Bilezikian   11. Hypocalcemic crisis: acute postoperative and chronic management of hypocalcemia   Stuart Campbell, Tara Corrigan, John Bilezikian and Alexander Shifrin   IV. Adrenal Glands    12. Acute adrenal hypertensive emergencies: pheochromocytoma, Cushing's, hyperaldosteronism   Monika Akula, Raquel Kristin Sanchez Ong, Alexander Shifrin and William F. Young Jr.   13. Pheochromocytoma: perioperative and Intraoperative management   Maureen McCartney Anderson, Tara Corrigan and Alexander Shifrin   14. Acute Adrenal insufficiency   Ramya Punati, Raquel Kristin Sanchez Ong and Stefan Richard Bornstein   V. Endocrine Pancreas and Pancreatic Neuroendocrine Tumors    15. Diabetic emergencies: ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia   Heidi Guzman and David W. Lam   16. Pancreatic neuroendocrine emergencies (gastrinoma, insulinoma, glucoganoma, VIPoma, somatostatinoma, PPoma)   Jason D. Prescott   VI. Neuroendocrine tumors (NETs): gastrointestinal neuroendocrine tumors    17. Carcinoid Syndrome and Carcinoid Crisis   Sarah Wonn and Rodney Pommier   VII. Pituitary    18. Post-Surgical and Post-Traumatic Hyponatremia   Ansha Goel and Joseph G. Verbalis   19. Diabetes Insipidus and Acute Hypernatremia   Chelsi Flippo, Christina Tatsi and Constantine Stratakis   20. Hypopituitarism   Sara Elisabeth Lubitz   21. Pituitary Apoplexy   Alison P. Seitz and Makoto Ishii   VIII. Endocrine emergencies during pregnancy    22. Endocrine emergencies during pregnancy   Christopher Goodier and Aundrea Eason Loftley   23. Graves' hyperthyroidism in pregnancy   Caroline T. Nguyen and Jorge H. Mestman   IX. Immunotherapy - associated endocrinopathies    24. Endocrinopathies Associated with Immune Checkpoint Inhibitors   Monica Girotra   X. Endocrine emergencies in children    25. Endocrine Responses in Critically ill and Trauma Patients   Lane Frasier, Jane J. Keating and Adam Michael Shiroff   26. Use of Potassium Iodide Ingestion in a Nuclear Emergency   Daniel Toft and Arthur B. Schneider","brand":"Elsevier - Health Sciences Division","offers":[{"title":"Default Title","offer_id":49401763889495,"sku":"9780323760973","price":92.69,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780323760973.jpg?v=1730478448"},{"product_id":"diabetes-secrets-9780323792622","title":"Diabetes Secrets","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"This book highlights the most important, up-to-date information as a whole, providing an easy-to-access resource for physicians of all levels.\"    ©Doody's Review Service, 2022, Maria Aguilera, MD (Cook County Health) Doody's Score: 4 Stars!\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eTop 100 Secrets 1 Diabetes Mellitus: Classification, Etiology and Pathogenesis  2 Comprehensive Medical Evaluation of Persons with Diabetes 3 Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome  4 Diabetic Nephropathy 5 Diabetic Retinopathy 6 Diabetic Neuropathies   7 Prevention of Macrovascular Complications  8 Diabetes and Non-alcoholic Fatty Liver Disease  9 Diabetes Management: Lifestyle Measures - Nutrition 10 Exercise and Diabetes  11 Diabetes Management: Insulin Therapy  12 Diabetes Management: Non-Insulin Therapies  13 Carbohydrate Counting and Precise Insulin Dosing  14 Type 2 Diabetes Management: Selecting Glycemic Targets and Choosing the Right Therapy 15 Diabetes Prevention 16 Diabetes and Pregnancy 17 Diabetes Management in Cancer Patients  18 Diabetes in Older Adults 19 Diabetes Management During Exercise, Sports and Competition  20 Diabetes Management in Hospitalized Patients  21 Continuous Glucose Monitoring 22 Continuous Glucose Monitoring Interpretation: Practice Cases 23 Insulin Pumps and Integrated Systems 24 Looping 25 Hypoglycemia 26 Weight Management in Patients with Type 2 Diabetes Mellitus 27 Identifying and Overcoming Barriers to Achieving Glucose Control  28 Diabetes in Africa   FM  BM 29 Diabetes Diagnosis and Management in New Zealand","brand":"Elsevier - Health Sciences Division","offers":[{"title":"Default Title","offer_id":49401767297367,"sku":"9780323792622","price":39.6,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780323792622.jpg?v=1730478459"},{"product_id":"adrenal-disorders-9780323792851","title":"Adrenal Disorders","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"This book provides practical guidance and clinical insight for the assessment and management of a wide variety of adrenal disorders using cased-based learning. It is a helpful resource for practitioners and trainees alike, especially for reviewing rarely seen cases with expert advice.\"    ©Doody's Review Service, 2022, Marcelo Ramirez, M.D. (Cook County Health)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSection A. Incidentally Discovered Adrenal Mass Case #1: 45-Year Old Woman with an Incidentally Discovered Large Adrenal Mass Case #2: Adrenal Mass in a Patient with History of Extra-adrenal Malignancy: the Role of Imaging  Case #3: Incidentally Discovered Adrenal Mass in a Patient with History of Extra-adrenal Malignancy: the Role of Adrenal Biopsy  Case #4: Nonfunctioning Lipid Rich Adrenocortical Adenoma-Role of Follow-up  Case #5: 54-Year Old Woman with an Incidentally Discovered Adrenal Mass and Abnormal Dexamethasone Suppression Test: Role of Adrenalectomy Case #6: Lipid Poor Adrenal Masses-The Case for Aggressive Management  Section B. Primary Aldosteronism Case #7: Primary Aldosteronism-When Adrenal Venous Sampling is not Needed Before Unilateral Adrenalectomy Case #8: Primary Aldosteronism with Unilateral Adrenal Nodule on Computed Tomography Case #9: Primary Aldosteronism with Bilateral Adrenal Nodules on Computed Tomography Case #10: Primary Aldosteronism Caused by Unilateral Adrenal Hyperplasia Case #11: Primary Aldosteronism in a Patient with Bilateral Macronodular Adrenal Hyperplasia and Associated Clinically Important Cortisol Co-secretion Case #12: Primary Aldosteronism in a Patient with an Adrenal Macroadenoma and Clinically Important Cortisol Co-secretion Case #13: Primary Aldosteronism in a Patient Treated with Spironolactone Case #14: Failed Catheterization of the Right Adrenal Vein-When Incomplete Adrenal Venous Sampling Data Can Be Used to Direct a Surgical Cure Case #15: Primary Aldosteronism: When Adrenal Venous Sampling Shows Suppressed Aldosterone Secretion From Both Adrenal Glands    Section C. ACTH-Independent Cushing Syndrome  Case #16: 28-Year-Old Woman with Remote History of Adrenal Mass Presenting with New Onset Hypertension and Weight Gain  Case #17: 26-Year-Old Woman with a Discrepant Work-up for Cushing Syndrome Subtype Case #18: 45-Year-Old Woman with Corticotropin-Independent Cushing Syndrome and Bilateral Adrenal Adenomas  Case #19: Corticotropin-Independent Cushing Syndrome in a Patient with \"Normal” Adrenal Imaging  Case #20: 66-Year-Old Woman with Corticotropin-Independent Hypercortisolism and Bilateral Macronodular Adrenal Hyperplasia Case #21: 35-Year-Old Woman with Low Bone Density and Fractures  Case #22: Carney Triad (Pentad) and Adrenal Adenoma with Clinically Important Cortisol Secretory Autonomy     Section D. Adrenal Cortical Carcinoma and Oncocytic Neoplasm  Case #23: Adrenal cortical carcinoma in a patient with history of adrenal incidentaloma Case #24: Unexpected Diagnosis of Adrenal Cortical Carcinoma: Role of Urinary Steroid Profiling Case #25: Oncocytic adrenocortical carcinoma  Case #26: Mitotane therapy in the ENSAT Stage II Adrenocortical Carcinoma Case #27: Cortisol-Secreting Metastatic Adrenocortical Carcinoma-Role for Surgical Debulking of the Primary Tumor Case #28: Adrenocortical Carcinoma and Severe Cushing Syndrome Case #29: Pure Aldosterone-Secreting Adrenocortical Carcinoma Case #30: Long-standing Primary Aldosteronism in a Patient Diagnosed with Metastatic Adrenocortical Carcinoma Case #31: Adrenocortical Carcinoma Associated with Lynch Syndrome Case #32: Adrenocortical Carcinoma Associated with Multiple Endocrine Neoplasia Type 1 Case #33: Adrenocortical Carcinoma Presenting with Inferior Vena Cava Thrombus Case #34: Management of Mitotane Therapy in Adrenocortical Carcinoma    Section E. Pheochromocytoma and Paraganglioma Case #35: Most Pheochromocytomas Grow Slowly Case #36: The \"Prebiochemical” Pheochromocytoma Case #37: Huge Catecholamine-Secreting Tumor Case#38: Metyrosine Use in a Patient with Metastatic Pheochromocytoma Case #39: Pheochromocytoma in a Patient with Neurofibromatosis Type 1 Case #40: New Diagnosis of Multiple Endocrine Neoplasia Type 2A in a Patient with Bilateral Pheochromocytomas  Case #41: Pheochromocytoma in a Patient with von Hippel Lindau Disease Case #42: Bilateral Pheochromocytoma in a Patient with MYC-associated Protein X (MAX) Genetic Predisposition Case #43: The Cystic Pheochromocytoma Case #44: Skull Base and Neck Paragangliomas-Considerations for the Endocrinologist Case #45: Cardiac Paraganglioma. Case #46: Pheochromocytoma in Multiple Endocrine Neoplasia Type 2B Case #47: Metastatic Paraganglioma-An Approach to Management and the Use Serial Imaging to Assess Rate of Tumor Progression Case #48: Metastatic Pheochromocytoma-Role for 68-Ga DOTATATE PET CT Case #49: Carney Triad (Pentad) and Catecholamine-Secreting Paragangliomas Case #50: Metastatic Paraganglioma-Role For Systemic Chemotherapy Case #51: Cryoablation Therapy for Metastatic Paraganglioma Case #52: Paraganglioma in a patient with cyanotic cardiac disease Case #53: Metastatic Paraganglioma-Role For External Beam Radiation Therapy     Section F. Corticotropin (ACTH)-Dependent Hypercortisolism Case #54:ACTH-Dependent Cushing Syndrome can be frequently misdiagnosed Case #55: ACTH-Dependent Cushing Syndrome-Role for Inferior Petrosal Sinus Sampling Case #56: ACTH-Dependent Cushing Syndrome-When Inferior Petrosal Sinus Sampling is Not Needed Case #57: Severe ACTH-Dependent Cushing Syndrome Due to a Pituitary Adenoma Ectopic Cushing Syndrome Associated with Multiple Endocrine Neoplasia Type 2B Case #59: Ectopic Cushing Syndrome Treated with Cryoablation   Case #60: Cyclical Ectopic Cushing Syndrome  Case #61: Mild Cushing Syndrome Associated with Ectopic Corticotropin Secretion  Case #62: Bilateral Adrenal Cryoablation in Corticotropin-dependent Cushing Syndrome Case #63: Cushing Syndrome Associated with Ectopic Corticotropin and Corticotropin Releasing Hormone Secreting Pheochromocytoma Case #64: Cushing Syndrome in the Setting of Multiple Endocrine Neoplasia Type 1    Section G. Other Adrenal Masses Case #65: Adrenal Myelolipoma-A Computed Tomography Diagnosis Case #66: Adrenal Schwannoma Case #67: Trauma-Related Unilateral Adrenal Hemorrhage Case #68: Bilateral Adrenal Hemorrhage Case #69: Primary Adrenal Teratoma Case #70: The Adrenal Stone Case #71: Simple Adrenal Cyst Case #72: Adrenal Cystic Lymphangioma Case #73: Adrenal Hemangioma Case #74: Adrenal Ganglioneuroma Case #75: 42-Year-Old Woman with a Large Adrenal Mass   Case #76: Primary Adrenal Leiomyosarcoma Case #77: Primary Adrenal Lymphoma Case #78. 39-Year-Old Man with a Large Adrenal Mass   Case # 79: 59-Year-Old Man with Enlarging Bilateral Adrenal Masses   Case # 80: 65-Year-Old Man with Primary Adrenal Insufficiency   Case #81: 47-Year-Old Man with Primary Adrenal Insufficiency Case #82: Bilateral Adrenal Myelolipoma-Think of Congenital Adrenal Hyperplasia Case #83: A Unilateral Lipid Poor Adrenal Mass-An Atypical Presentation of Adrenal Histoplasmosis Case #84: Bilateral Macronodular Adrenal Hyperplasia (BMAH) in the Setting of Multiple Endocrine Neoplasia Type 1 Case #85: Pseudo-Adrenal Masses    Section H. Adrenal and Ovarian Hyperandrogenism Case #86: A Huge Adrenal Myelolipoma in a Patient with a Suboptimally Controlled Congenital Adrenal Hyperplasia Case #87: Balancing Glucocorticoid and Androgen Excess in Congenital Adrenal Hyperplasia Case #88: Dehydroepiandrosterone-sulfate (DHEA-S): The \"Love it” or \"Hate it” Hormone Case #89: Sorting out the Source of Androgen Excess in a Postmenopausal Woman with an Adrenal and an Ovarian Mass Case #90: Primary Testosterone-Secreting Adrenocortical Carcinoma in a Premenopausal Woman. Case #91: Premenopausal Woman with Testosterone-secreting Ovarian Tumor Case #92: Sorting out the Source of Androgen Excess in a Postmenopausal Woman with an Adrenal Mass Case #93: Testosterone-Secreting Benign Adrenal Adenoma in a Postmenopausal Woman    Section I. Adrenal Disorders in Pregnancy Case #94: Malignant Pheochromocytoma in Pregnancy Case #95: Catecholamine-Secreting Paraganglioma in Pregnancy Case #96: The Peripartum Diagnosis of Pheochromocytoma and a Genetic Mystery Solved Case #97. History of Pregnancy in a 41-Year-Old Woman with Undiagnosed Cushing syndrome Case #98: Pregnancy in a Patient with Primary Adrenal Insufficiency  Case #99: Pregnancy in a Patient with 21-Hydroxylase Deficiency  Case #100: Primary Aldosteronism in Pregnancy","brand":"Elsevier - Health Sciences Division","offers":[{"title":"Default Title","offer_id":49401767362903,"sku":"9780323792851","price":92.69,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780323792851.jpg?v=1730478459"},{"product_id":"yen-jaffes-reproductive-endocrinology-9780323810074","title":"Yen  Jaffes Reproductive Endocrinology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"This book covers reproductive endocrinology with bulleted lists under the chapter headings, providing excellent summaries of the content for quick and easy review. This ninth edition is an update to the previous version, which was published in 2017.\" ©Doody's Review Service, 2023, Prathayini Subarajan, DO (Loyola University Stritch School of Medicine) Doody's Score: 5 Stars!\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePART 1: THE FUNDAMENTALS OF HUMAN REPRODUCTION  Chapter 1 Neuroendocrinology of Reproduction  Chapter 2 Gonadotropic Hormones and Their Receptors  Chapter 3 Prolactin  Chapter 4 Steroidogenesis and Lipid Mediators  Chapter 5 Steroid Hormone Action  Chapter 6 Growth Factors  Chapter 7 Neuroendocrine Control of the Menstrual Cycle  Chapter 8 The Ovarian Life Cycle  Chapter 9 Meiosis, Fertilization and Embryo Development- NEW  Chapter 10 Structure and Function of the Female Reproductive Tract  Chapter 11 Endocrinology of Pregnancy  Chapter 12 The Breast  Chapter 13 The Hypothalamic-Pituitary Unit, Testis and Male Accessory Organs  Chapter 14 Menopause and Aging  Chapter 15 Male Reproductive Aging  Chapter 16 Immunology of Reproduction  :PART 2: PATHOPHYSIOLOGY AND THERAPY  Chapter 17 Disorders of Sexual Development  Chapter 18 Puberty  Chapter 19 Nutrition and Reproduction  Chapter 20 Environmental Factors and Reproduction  Chapter 21 Pathophysiology of Neuroendocrine Disorders of Reproduction  Chapter 22 Polycystic Ovary Syndrome and Hyperandrogenic States  Chapter 23 Female Infertility  Chapter 24 Male Infertility  Chapter 25 Endocrine Diseases Affecting Reproduction  Chapter 26 Benign Uterine Diseases  Chapter 27 Endometriosis  Chapter 28 Recurrent Pregnancy Loss  Chapter 29 Endocrine Diseases in Pregnancy  Chapter 30 Hormone Responsive Cancers  PART 3: REPRODUCTIVE TECHNOLOGIES  Chapter 31 Medical Approaches to Ovarian Stimulation  Chapter 32 Assisted Reproduction  Chapter 33 Gamete and Embryo Manipulation  Chapter 34 Laboratory Assessment  Chapter 35 Imaging  Chapter 36 Emerging Technologies- NEW  Chapter 37 Contraception","brand":"Elsevier - Health Sciences Division","offers":[{"title":"Default Title","offer_id":49401769230679,"sku":"9780323810074","price":190.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780323810074.jpg?v=1730478466"},{"product_id":"polycystic-ovary-syndrome-9780323879323","title":"Polycystic Ovary Syndrome","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSECTION I Overview of Polycystic Syndrome 1 Introduction to Polycystic Ovary Syndrome 2 Polycystic Ovary Syndrome Phenotypes 3 Polycystic Ovary Syndrome Adolescents SECTION II Pathogenesis and Clinical Presentation 4 Pathophysiology of Polycystic Ovary Syndrome 5 Interplay of Adipocytokines With Polycystic Ovary Syndrome 6 Crosstalk between Oxidative Stress and Chronic Inflammation in Pathogenesis of Polycystic Ovary Syndrome 7 Polycystic Ovary Syndrome and Subfertility: Ovulation Dysregulation and Fertility Problems (Clinical Features and Pathophysiology) 8 Clinical Features and Presentation of Polycystic Ovary Syndrome 56 9 Diagnostic Criteria for Polycystic Ovary Syndrome 10 Polycystic Ovary Syndrome and Metabolic Syndrome: Risks in Later Life 11 Polycystic Ovary Syndrome and Mental Health 12 Polycystic Ovary Syndrome and Nonalcoholic Fatty Liver Disease 13 Male Polycystic Ovary Syndrome Equivalent SECTION III Management of Polycystic Ovary Syndrome and Associated Comorbidities 14 Pharmacologic Management of PCOS: Menstrual Irregularities 15 Pharmacologic Management for Polycystic Ovary Syndrome: Hirsutism and Acne 16 Pharmacologic Management for Polycystic Ovary Syndrome: Weight Loss 17 Role of Insulin Sensitizers in the Management of Polycystic Ovary Syndrome 18 Cardiovascular Risk Reduction in Polycystic Ovary Syndrome 19 Management of Subfertility in Polycystic Ovary Syndrome 20 Management of Associated Risks of Pregnancy in Polycystic Ovary Syndrome 21 Importance of Lifestyle Modifications 22 Role of Complementary and Alternative Medicine in Polycystic Ovary Syndrome 23 Evidence-Based Recommendations for Clinical Practice (Future Directions: Research and Practice) SECTION IV Global Approach to Polycystic Ovary Syndrome 24 Polycystic Ovary Syndrome in South Asians 25 Situation Analysis of Polycystic Ovary Syndrome in Central and East Asia 26 Situational Analysis of Polycystic Ovary Syndrome in Southeast Asia 27 Situation Analysis of Polycystic Ovary Syndrome in Western Asia 28 Situation Analysis, Cultural Beliefs, Lifestyle,and the Psychological Impact of Polycystic Ovary Syndrome in Europe 29 Global Approach to Polycystic Ovary Syndrome in Africa 30 Polycystic Ovary Syndrome in North America","brand":"Elsevier - Health Sciences Division","offers":[{"title":"Default Title","offer_id":49401779913047,"sku":"9780323879323","price":73.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780323879323.jpg?v=1730478499"},{"product_id":"aroused-9780393239607","title":"Aroused","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eA guided tour through the strange science of hormones and the age-old quest to control them.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"A rollicking history certain to get your intellectual and physiologic juices flowing. Adrenaline-tinged tales and hot flashes of history—just what the doctor ordered.\" -- Lisa Sanders, New York Times Magazine Diagnosis columnist\u003cbr\u003e\"A sweeping, glorious story of hormones, threaded through with sex, suffering, neurology, biology, medicine and self-discovery, Randi Hutter Epstein’s book manages to excite the imagination as well as calm it. The story is grippingly told, and Epstein manages to bring a whole system of science alive to her reading public.\" -- Siddhartha Mukherjee, author of The Gene: An Intimate History\u003cbr\u003e\"Hormones may be ringmasters of the bodily circus, controlling everything from sex to metabolic function, but in this invigorating history they become stars of the show.\" -- Nature\u003cbr\u003e\"Congratulations to my friend @randihepstein on the publication of her book! I loved reading it and highly recommend it to anyone interested in public health or your own health!\" -- Chelsea Clinton\u003cbr\u003e\"I’m hitting up the public library for two. The first is Randi Hutter Epstein’s \u003cem\u003eAroused: The history of hormones and how they control just about everything\u003c\/em\u003e (Norton), which I hope will answer the most banal of questions as I continue my reluctant march through midlife: What the hell is happening to me?\" -- Jennie Erin Smith, Summer Books 2018 - Times Literary Supplement\u003cbr\u003e\"The field of endocrinology, as this compelling history shows, has manifested extremes of ingenuity and hubristic error.\" -- The New Yorker\u003cbr\u003e\"A well-written and informative book on the history of hormone research.\" -- The New York Times Book Review","brand":"WW Norton \u0026 Co","offers":[{"title":"Default Title","offer_id":49401980911959,"sku":"9780393239607","price":19.94,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780393239607.jpg?v=1730479033"},{"product_id":"muscle-metabolism-4-frontiers-in-animal-diabetes-research-9780415272100","title":"Muscle Metabolism 4 Frontiers in Animal Diabetes","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eDiabetes research on models comprising intact animal tissues, cell cultures and isolated pancreatic islets is essential for understanding the pathogenesis of the disease as well as the mechanisms responsible for the chronic complications associated with it. Enormous advances in the understanding of the development of diabetes and its prevention have recently been derived from work with such animal models. This book presents the state-of-the-art knowledge in the field of diabetes research directed at understanding the mechanisms governing the development of skeletal muscle insulin resistance. Muscle Metabolism will be of significant interest for those researching diabetes at an experimental level in both academia and the pharmaceutical industry. In addition, it will also be of interest to researchers in the fields of obesity, metabolism, endocrinology and molecular biology.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eInsulin Signaling. Overview: Tyrosine Kinase Signaling in Insulin Action. Defects in Early Insulin Signaling in Skeletal Muscle. Defects in Intermediate Insulin Signaling in Skeletal Muscle: (PI) 3-kinase and Glucose Transport. Glucose Transport. Glucose Transport in Muscle. The GLUT4 Compartments of Skeletal Muscle. Substrate Utilization. Adverse Metabolic Consequences of Hyperglycemia (\"Glucose Toxicity\"): Implications for the Pathogenesis of Diabetes Mellitus. Cellular Mediators of Glucose-Induced Autoregulation of Hexose Transport. Physiological Adaptations in Glucose Utilization of Skeletal Muscle. Fatty Acids and Muscle Insulin Resistance. Role of AMP Kinase and Malonyl CoA in Exercise-stimulated Skeletal Muscle Metabolism and Insulin Action. Transgenic and Genetic Models. The Use of Mouse Transgenic and Homologous Recombination Technologies to Analyze the Physiologic Basis of Glucose Homeostasis. Transgenic Approaches to Insulin Signaling. Transgenic Models to Study Glucose Transport and Metabolism in Skeletal Muscle. Diabetic Animals. Insulin Resistance in Skeletal Muscle: a Role for Impaired Insulin Activation of Glycogen Synthase. Muscle GLUT4 Traffic and Insulin Resistant States. Glucose Transport in Heart: Special Emphasis on Insulin Resistance and NIDM. Cellular Redox State and Insulin Sensitivity: Potential Role of Lipoic Acid. Exercise and Aging. Exercise Training and Muscle Insulin Resistance: Cellular Adaptations. Effects of Physical Exercise on the Decreased Insulin Action Caused by Aging. Effects of Aging on Glucose Homeostasis: Cellular Approaches. Application to Humans. Insulin Resistance: Whole Body Mechanisms in Humans. Cellular Mechanisms.","brand":"Taylor \u0026 Francis Ltd","offers":[{"title":"Default Title","offer_id":49402083311959,"sku":"9780415272100","price":265.16,"currency_code":"GBP","in_stock":true}]},{"product_id":"metabolic-syndrome-9780470343425","title":"Metabolic Syndrome","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eMETABOLIC SYNDROME\u003c\/b\u003e \u003cp\u003e\u003cb\u003eA comprehensive look at the fight against the metabolic syndrome epidemic \u003c\/b\u003e  \u003c\/p\u003e\u003cp\u003eIncreasing risk of cardiovascular disease and diabetes, the metabolic syndrome is a world health problem that demands attention from all levels of the health care industry. \u003ci\u003eMetabolic Syndrome: Underlying Mechanisms and Drug therapies\u003c\/i\u003e extensively covers the metabolic syndrome with an emphasis on drug discovery efforts, providing a context of molecular mechanisms and drug pharmacology for pharmaceutical scientists.  \u003c\/p\u003e\u003cp\u003eThe book starts by examining the physiology of metabolic tissues under normal and disease states, followed by discussions of metabolic diseases and clinical complications. The development of drug therapies based on emerging science is then covered extensively. In addition, there is an in-depth look into the metabolic pathways and dysfunctions in metabolic disease, especially type 2 diabetes and lipid disorders. Finally, a chapter is devoted to past succ\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"This is an outstanding addition to the current body of work on the metabolic syndrome. I thought it particularly exhaustive in its review of the literature, making it an excellent resource for scouring the primary literature, and found the duality of current and future treatment approaches particularly insightful.\" (Doody's, 21 October 2011)  \u003c\/p\u003e\u003cp\u003e \"The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications.\" (Pharmiweb, 1 March 2011)\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eIntroduction ix\u003cbr\u003e \u003ci\u003eMinghan Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart One The Physiology of Metabolic Tissues Under Normal and Disease States\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Gut as an Endocrine Organ: the Role of Nutrient Sensing in Energy Metabolism 3\u003cbr\u003e \u003ci\u003eMinghan Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. Central Glucose Sensing and Control of Food Intake and Energy Homeostasis 29\u003cbr\u003e \u003ci\u003eLourdes Mounien and Bernard Thorens\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3. Abnormalities in Insulin Secretion in Type 2 Diabetes Mellitus 53\u003cbr\u003e \u003ci\u003eTaly Meas and Pierre-Jean Guillausseau\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4. Adipokine Production by Adipose Tissue: A Novel Target for Treating Metabolic Syndrome and its Sequelae 73\u003cbr\u003e \u003ci\u003eVanessa DeClercq, Danielle Stringer, Ryan Hunt, Carla G. Taylor, and Peter Zahradka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. Hepatic Metabolic Dysfunctions in Type 2 Diabetes: Insulin Resistance and Impaired Glucose Production and Lipid Synthesis 133\u003cbr\u003e \u003ci\u003eRuojing Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6. Energy Metabolism in Skeletal Muscle and its Link to Insulin Resistance 157\u003cbr\u003e \u003ci\u003eMinghan Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart Two Metabolic Diseases and Current Therapies\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7. Mechanisms and Complications of Metabolic Syndrome 179\u003cbr\u003e \u003ci\u003eMinghan Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. Emerging Therapeutic Approaches for Dyslipidemias Associated with High LDL and Low HDL 199\u003cbr\u003e \u003ci\u003eMargrit Schwarz and Jae B. Kim\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. Mechanism of Action of Niacin: Implications for Atherosclerosis and Drug Discovery 235\u003cbr\u003e \u003ci\u003eDevan Marar, Shobha H. Ganji, Vaijinath S. Kamanna, and Moti L. Kashyap\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Current Antidiabetic Therapies and Mechanisms 253\u003cbr\u003e \u003ci\u003eMinghan Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart Three Drug Targets for Antidiabetic Therapies\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11. GLP-1 Biology, Signaling Mechanisms, Physiology, and Clinical Studies 281\u003cbr\u003e \u003ci\u003eRemy Burcelin, Cendrine Cabou, Christophe Magnan, and Pierre Gourdy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12. Dipeptidyl Peptidase IV Inhibitors for Treatment of Diabetes 327\u003cbr\u003e \u003ci\u003eC.H.S. McIntosh, S.-J. Kim, R.A. Pederson, U. Heiser, and H.-U. Demuth\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13. Sodium Glucose Cotransporter 2 Inhibitors 359\u003cbr\u003e \u003ci\u003eMargaret Ryan and Serge A. Jabbour\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14. Fibroblast Growth Factor 21 as a Novel Metabolic Regulator 377\u003cbr\u003e \u003ci\u003eRadmila Micanovic, James D. Dunbar, and Alexei Kharitonenkov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15. Sirtuins as Potential Drug Targets for Metabolic Diseases 391\u003cbr\u003e \u003ci\u003eQiang Tong\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16. 11β-Hydroxysteroid Dehydrogenase Type 1 as a Therapeutic Target for Type 2 Diabetes 423\u003cbr\u003e \u003ci\u003eClarence Hale and David J. St. Jean, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17. Monoclonal Antibodies for the Treatment of Type 2 Diabetes: A Case Study with Glucagon Receptor Blockade 459\u003cbr\u003e \u003ci\u003eHai Yan, Wei Gu, and Murielle Veniant-Ellison\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart Four Lessons Learned and Future Outlook\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18. Drug Development for Metabolic Diseases: Past, Present and Future 471\u003cbr\u003e \u003ci\u003eMinghan Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 489 \u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402316095831,"sku":"9780470343425","price":119.65,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470343425.jpg?v=1730480046"},{"product_id":"mastering-diabetes-9780593542040","title":"Mastering Diabetes","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e\u003cb\u003eThe instant \u003ci\u003eNew York Times\u003c\/i\u003e bestseller.\u003cbr\u003e\u003cbr\u003eA groundbreaking method to master all types of diabetes by reversing insulin resistance. \u003c\/b\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003eCurrent medical wisdom advises that anyone suffering from diabetes or prediabetes should eat a low-carbohydrate, high-fat diet. But in this revolutionary book, Cyrus Khambatta, PhD, and Robby Barbaro, MPH, rely on a century of research to show that advice is misguided. While it may improve short-term blood glucose control, such a diet also increases the long-term risk for chronic diseases like cancer, high blood pressure, high cholesterol, chronic kidney disease, and fatty liver disease.\u003cbr\u003e\u003cbr\u003eThe revolutionary solution is to eat a low-fat plant-based whole-food diet, the most powerful way to reverse insulin resistance in all types of diabetes: type 1, type 1.5, type 2, prediabetes, and gestational diabetes.\u003cbr\u003e\u003cbr\u003eAs the creators of the extraordinary and effective Mastering Diabetes Method, Khambatta and Barbaro lay out a","brand":"Penguin Young Readers","offers":[{"title":"Default Title","offer_id":49403266171223,"sku":"9780593542040","price":17.0,"currency_code":"GBP","in_stock":true}]},{"product_id":"metabolic-living-9780822360872","title":"Metabolic Living","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIn \u003ci\u003eMetabolic Living\u003c\/i\u003e Harris Solomon studies obesity and diabetes in Mumbai, India, presenting a new narrative of metabolic illness in which it is less about the overconsumption of food than it is about the body's relationship to its environment and the substances it absorbs. \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"\u003ci\u003eMetabolic Living\u003c\/i\u003e is an important contribution to contemporary medical anthropology, especially in regards to the study of disease chronicity and to contemporary South Asian studies. In addition, Solomon provides a welcome challenge to the existing universalizing public health discourse on 'globesity.' Even while describing the seeming inevitability of metabolic disease in Mumbai, he uncovers the complex elements of social life that contribute to and circulate around it, and the suffering that stems from it. The focus on metabolism and absorption opens up new ways of viewing intersections between bodies and their environments, as well as new ways of thinking about urban vitality in 21st century India.\" -- Andrea S. Wiley * Anthropological Quarterly *\u003cbr\u003e\"The book offers a novel way to talk about metabolic illnesses in urban space, often directly or indirectly talking back to medical and public health discourses on food, bodies, and urban and urbanizing spaces.... The poetic humanity of metabolic precariousness in India is visible in every page of this rich ethnographic narrative, making it a valuable contribution to literatures in medical anthropology, science studies, area studies, food studies, and public health policy.\" -- Nayantara Sheoran Appleton * Medical Anthropology Quarterly *\u003cbr\u003e“A wonderfully evocative ethnography, Solomon’s book makes one reflect on the very nature of metabolic syndrome.... Through this book, Solomon ... challeng[es] medical experts to consider a multi-layered approach to solving the issues of obesity and diabetes that plague contemporary India.\" -- Gauri Anilkumar Pitale * FoodAnthropology *\u003cbr\u003e\"Pointing out that food is never just food—that it incorporates joyous and toxic social lives and historical traces—the book effectively shifts the conversation about metabolism away from junk food or obese bodies and towards absorptive and thoroughly social processes.\u003ci\u003e Metabolic Living\u003c\/i\u003e provides health-care professionals valuable insight into how people are living with metabolic illness.\" -- Emily Yates-Doerr * The Lancet *\u003cbr\u003e\"In the sophistication of its crafting, \u003ci\u003eMetabolic Living\u003c\/i\u003e achieves its tricky aspiration to understand metabolism both as a tool for ethnographic observation and as a site of anthropological analysis. Indeed, it is this blurring of instrument and object, the ethnographer and the ethnographic, that gives \u003ci\u003eMetabolic Living\u003c\/i\u003e its persuasive force.\" -- Dwaipayan Banerjee * American Anthropologist *\u003cbr\u003e\"This study is an excellent observation of current anxieties over prosperity diseases in urban India, locating the connections between food, bodies, and environments. While Solomon’s ethnographical accounts revolve around different sets of frameworks and narrations of common people, patients, nutritionists and experts, he cautiously avoided stigmatic fears and pain and presented metabolic suffering throughout within a cultural context.\" -- Santhosh Abraham * South Asia Research *\u003cbr\u003e\"Solomon takes us through domestic kitchens and social service centers, slaughterhouses and food processing plants, streets and street-side food stalls, and waiting rooms and hospitals to provide nuanced and insightful descriptions of life in Mumbai.\" -- GauriI Pathak * Journal of Anthropological Research *\u003cbr\u003e\"\u003ci\u003eMetabolic Living\u003c\/i\u003e is the first ethnographic monograph on the diabetes epidemic in South Asia, and this alone marks it as an important contribution to the study of health and illness in the subcontinent. It also provides an evocative and complex picture of being a person with a metabolic illness in Mumbai.\"\u003cbr\u003e   -- Lesley Jo Weaver * Journal of Asian Studies *\u003cbr\u003e\"\u003ci\u003eMetabolic Living\u003c\/i\u003e is a rich, ambitious book whose theoretical and ethnographic model builds bridges across chapters with disparate topics and actors. . . . For readers curious about how to research and write the complexities of embodiment – and are open to experimenting with how to get there – \u003ci\u003eMetabolic Livi\u003c\/i\u003eng is a productive and exhilarating read.\" -- Stephanie Maroney * Senses and Society *\u003cbr\u003e\"Solomon’s book is compelling, palpable in fact, in its stories about the invisible and ineluctable ways that medicines or contaminants enter foods and bodies. The ethnography brings the reader into environments that are dangerous and mundane, pleasurable, and unalterable.\u003ci\u003e Metabolic Living\u003c\/i\u003e brings into focus the ways that people navigate these dynamic alchemies.\" -- Jessica Hardin * Journal of the Royal Anthropological Institute *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eAcknowledgments  ix\u003cbr\u003e\u003cbr\u003e Introduction  1\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Birthday Cakes  27\u003cbr\u003e\u003cbr\u003e 1. The Thin-Fat Indian  31\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Mango Madness  65\u003cbr\u003e\u003cbr\u003e 2. The Taste No Chef Can Give  69\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. The Ration Card  99\u003cbr\u003e\u003cbr\u003e 3. Readying the Home  105\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Stamps  141\u003cbr\u003e\u003cbr\u003e 4. Lines of Therapy  145\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Waiting Room Walls  187\u003cbr\u003e\u003cbr\u003e 5. Gut Attachments  193\u003cbr\u003e\u003cbr\u003e Conclusion. Metabolic Mumbai  225\u003cbr\u003e\u003cbr\u003e Notes  235\u003cbr\u003e\u003cbr\u003e Bibliography  253\u003cbr\u003e\u003cbr\u003e Index  271","brand":"Duke University Press","offers":[{"title":"Default Title","offer_id":49406094213463,"sku":"9780822360872","price":98.6,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780822360872.jpg?v=1730494505"},{"product_id":"metabolic-living-9780822361015","title":"Metabolic Living","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIn \u003ci\u003eMetabolic Living\u003c\/i\u003e Harris Solomon studies obesity and diabetes in Mumbai, India, presenting a new narrative of metabolic illness in which it is less about the overconsumption of food than it is about the body's relationship to its environment and the substances it absorbs. \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"\u003ci\u003eMetabolic Living\u003c\/i\u003e is an important contribution to contemporary medical anthropology, especially in regards to the study of disease chronicity and to contemporary South Asian studies. In addition, Solomon provides a welcome challenge to the existing universalizing public health discourse on 'globesity.' Even while describing the seeming inevitability of metabolic disease in Mumbai, he uncovers the complex elements of social life that contribute to and circulate around it, and the suffering that stems from it. The focus on metabolism and absorption opens up new ways of viewing intersections between bodies and their environments, as well as new ways of thinking about urban vitality in 21st century India.\" -- Andrea S. Wiley * Anthropological Quarterly *\u003cbr\u003e\"The book offers a novel way to talk about metabolic illnesses in urban space, often directly or indirectly talking back to medical and public health discourses on food, bodies, and urban and urbanizing spaces.... The poetic humanity of metabolic precariousness in India is visible in every page of this rich ethnographic narrative, making it a valuable contribution to literatures in medical anthropology, science studies, area studies, food studies, and public health policy.\" -- Nayantara Sheoran Appleton * Medical Anthropology Quarterly *\u003cbr\u003e“A wonderfully evocative ethnography, Solomon’s book makes one reflect on the very nature of metabolic syndrome.... Through this book, Solomon ... challeng[es] medical experts to consider a multi-layered approach to solving the issues of obesity and diabetes that plague contemporary India.\" -- Gauri Anilkumar Pitale * FoodAnthropology *\u003cbr\u003e\"Pointing out that food is never just food—that it incorporates joyous and toxic social lives and historical traces—the book effectively shifts the conversation about metabolism away from junk food or obese bodies and towards absorptive and thoroughly social processes.\u003ci\u003e Metabolic Living\u003c\/i\u003e provides health-care professionals valuable insight into how people are living with metabolic illness.\" -- Emily Yates-Doerr * The Lancet *\u003cbr\u003e\"In the sophistication of its crafting, \u003ci\u003eMetabolic Living\u003c\/i\u003e achieves its tricky aspiration to understand metabolism both as a tool for ethnographic observation and as a site of anthropological analysis. Indeed, it is this blurring of instrument and object, the ethnographer and the ethnographic, that gives \u003ci\u003eMetabolic Living\u003c\/i\u003e its persuasive force.\" -- Dwaipayan Banerjee * American Anthropologist *\u003cbr\u003e\"This study is an excellent observation of current anxieties over prosperity diseases in urban India, locating the connections between food, bodies, and environments. While Solomon’s ethnographical accounts revolve around different sets of frameworks and narrations of common people, patients, nutritionists and experts, he cautiously avoided stigmatic fears and pain and presented metabolic suffering throughout within a cultural context.\" -- Santhosh Abraham * South Asia Research *\u003cbr\u003e\"Solomon takes us through domestic kitchens and social service centers, slaughterhouses and food processing plants, streets and street-side food stalls, and waiting rooms and hospitals to provide nuanced and insightful descriptions of life in Mumbai.\" -- GauriI Pathak * Journal of Anthropological Research *\u003cbr\u003e\"\u003ci\u003eMetabolic Living\u003c\/i\u003e is the first ethnographic monograph on the diabetes epidemic in South Asia, and this alone marks it as an important contribution to the study of health and illness in the subcontinent. It also provides an evocative and complex picture of being a person with a metabolic illness in Mumbai.\"\u003cbr\u003e   -- Lesley Jo Weaver * Journal of Asian Studies *\u003cbr\u003e\"\u003ci\u003eMetabolic Living\u003c\/i\u003e is a rich, ambitious book whose theoretical and ethnographic model builds bridges across chapters with disparate topics and actors. . . . For readers curious about how to research and write the complexities of embodiment – and are open to experimenting with how to get there – \u003ci\u003eMetabolic Livi\u003c\/i\u003eng is a productive and exhilarating read.\" -- Stephanie Maroney * Senses and Society *\u003cbr\u003e\"Solomon’s book is compelling, palpable in fact, in its stories about the invisible and ineluctable ways that medicines or contaminants enter foods and bodies. The ethnography brings the reader into environments that are dangerous and mundane, pleasurable, and unalterable.\u003ci\u003e Metabolic Living\u003c\/i\u003e brings into focus the ways that people navigate these dynamic alchemies.\" -- Jessica Hardin * Journal of the Royal Anthropological Institute *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eAcknowledgments  ix\u003cbr\u003e\u003cbr\u003e Introduction  1\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Birthday Cakes  27\u003cbr\u003e\u003cbr\u003e 1. The Thin-Fat Indian  31\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Mango Madness  65\u003cbr\u003e\u003cbr\u003e 2. The Taste No Chef Can Give  69\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. The Ration Card  99\u003cbr\u003e\u003cbr\u003e 3. Readying the Home  105\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Stamps  141\u003cbr\u003e\u003cbr\u003e 4. Lines of Therapy  145\u003cbr\u003e\u003cbr\u003e\u003ci\u003eInterlude\u003c\/i\u003e. Waiting Room Walls  187\u003cbr\u003e\u003cbr\u003e 5. Gut Attachments  193\u003cbr\u003e\u003cbr\u003e Conclusion. Metabolic Mumbai  225\u003cbr\u003e\u003cbr\u003e Notes  235\u003cbr\u003e\u003cbr\u003e Bibliography  253\u003cbr\u003e\u003cbr\u003e Index  271","brand":"Duke University Press","offers":[{"title":"Default Title","offer_id":49406094672215,"sku":"9780822361015","price":25.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780822361015.jpg?v=1730494506"},{"product_id":"the-hunt-for-the-parathyroids-9781118299692","title":"The Hunt for the Parathyroids","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe Hunt for the Parathyroid Gland is a part fact, part fiction overview of the discovery of the parathyroid gland by a Swedish scientist in 1880.    The discovery of the parathyroid gland in humans in 1880 by an unknown Swedish medical student, Ivar Viktor Sandström, ended a 30 year search for its exact location within the human body, following its discovery in an Indian rhino 30 years before. It is one of the most engaging and remarkable stories in the history of medicine. This book offers a fascinating insight into its discovery.    Endocrinologists and ENT health professionals, both in clinical practice and researchers, as well as anyone with an interest in the history of medicine, will find this a fascinating insight into one of the 19th century's key medical discoveries.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eForeword 4\u003cbr\u003e    \u003cbr\u003e Introduction 7\u003cbr\u003e       \u003cbr\u003e 1. Sandström's Discovery 11\u003c\/p\u003e \u003cp\u003e2. Unexpected Problems 26\u003c\/p\u003e \u003cp\u003e3. The Age of Glorious Discoveries 38\u003c\/p\u003e \u003cp\u003e4. A Gland in Search of a Function 44\u003c\/p\u003e \u003cp\u003e5. The Calcium Connection 51\u003c\/p\u003e \u003cp\u003e6. Hormones and Organotherapy 64\u003cbr\u003e  \u003cbr\u003e 7. The Priority Dispute 71\u003c\/p\u003e \u003cp\u003e8. Immortal Patients 85\u003c\/p\u003e \u003cp\u003e9. A Disease in Disguise 98\u003c\/p\u003e \u003cp\u003e10. The Elusive Hormone 109\u003c\/p\u003e \u003cp\u003e11. The Language of God 121\u003c\/p\u003e \u003cp\u003e12. The Pharmacological Paradox 130\u003c\/p\u003e \u003cp\u003eReferences and Notes 138\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":49406847942999,"sku":"9781118299692","price":23.7,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118299692.jpg?v=1730497327"},{"product_id":"hyaluronic-acid-9781118633793","title":"Hyaluronic Acid","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eHyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHyaluronic Acid: Production, Properties, Application in Biology and Medicine\u003c\/i\u003e consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003eIntroduction xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 The History of Hyaluronic Acid Discovery, Foundational Research and Initial Use 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Discovery 1\u003c\/p\u003e \u003cp\u003e1.2 Foundational Research 2\u003c\/p\u003e \u003cp\u003e1.3 Initial Medical Applications 3\u003c\/p\u003e \u003cp\u003e1.4 Sources of Hyaluronan 4\u003c\/p\u003e \u003cp\u003e1.5 Current Medical Study and Use 6\u003c\/p\u003e \u003cp\u003e1.6 Impact and Future Directions 7\u003c\/p\u003e \u003cp\u003eReferences 7\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 The Biological Role of Hyaluronic Acid 9\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Hyaluronic Acid Phylogenesis 9\u003c\/p\u003e \u003cp\u003e2.1.1 Polysaccharide Structure and the Problems of Phylogenesis 13\u003c\/p\u003e \u003cp\u003e2.1.2 Physico-Chemical and Functional Differences of Polysaccharides 18\u003c\/p\u003e \u003cp\u003e2.1.3 Biochemical Features of Hyaluronic Acid and Other Glycosaminoglycans 20\u003c\/p\u003e \u003cp\u003e2.2 Functions of Hyaluronan in Human Ontogenesis 22\u003c\/p\u003e \u003cp\u003e2.2.1 Role of Hyaluronic Acid in Fertilization 22\u003c\/p\u003e \u003cp\u003e2.2.2 Hyaluronan and Other Glucosaminoglycans in Cell Division, Migration and Differentiation 25\u003c\/p\u003e \u003cp\u003e2.2.3 Hyaluronic Acid and Sulfated Glycosaminoglycans in Maintaining a Differentiated Status of Cells 33\u003c\/p\u003e \u003cp\u003e2.2.4 Hyaluronan and Induction of Cellular Cycles for Differentiated Cells 35\u003c\/p\u003e \u003cp\u003e2.2.5 The Source of Hyaluronic Acid’s Functional Properties and the Dynamics of its Synthesis and Degradation 44\u003c\/p\u003e \u003cp\u003e2.2.6 The Rules of Biopolymer Functional Cleavage 52\u003c\/p\u003e \u003cp\u003e2.3 Hyaluronan Signalling Systems 53\u003c\/p\u003e \u003cp\u003e2.4 Hyaluronan Functions in the Extracellular Matrix 59\u003c\/p\u003e \u003cp\u003e2.4.1 Extracellular Space 60\u003c\/p\u003e \u003cp\u003e2.4.2 Composition and Functioning of the Extracellular Matrix 60\u003c\/p\u003e \u003cp\u003e2.4.3 The Role of Hyaluronan in Transportation of Substances through the Extracellular Matrix: Diffusion, Osmosis, Electro-Osmosis and Vesicular Transportation 63\u003c\/p\u003e \u003cp\u003e2.4.4 Hyaluronan in the Extracellular Matrix of Different Connective Tissues 65\u003c\/p\u003e \u003cp\u003eReferences 67\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Methods of Hyaluronic Acid Production 77\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Hyaluronan Sources and Extraction 77\u003c\/p\u003e \u003cp\u003e3.1.1 Hyaluronan Production from Animal Sources: General Methods 77\u003c\/p\u003e \u003cp\u003e3.1.2 Hyaluronan Purification 78\u003c\/p\u003e \u003cp\u003e3.1.3 The Chemical Production of Hyaluronan from Chicken Combs 81\u003c\/p\u003e \u003cp\u003e3.1.4 HA Production for Ophthalmology 82\u003c\/p\u003e \u003cp\u003e3.2 Bacterial Methods of Hyaluronic Acid Production 84\u003c\/p\u003e \u003cp\u003e3.3 Hyaluronan Destruction during Production, Storage and Sterilization 85\u003c\/p\u003e \u003cp\u003e3.4 Enzymatic Destruction of Hyaluronan 86\u003c\/p\u003e \u003cp\u003e3.4.1 Hyaluronidase Classification 86\u003c\/p\u003e \u003cp\u003e3.4.2 Properties and Functions of Hyaluronidases 87\u003c\/p\u003e \u003cp\u003e3.5 Non-Enzymatic Destruction of Hyaluronan 88\u003c\/p\u003e \u003cp\u003e3.5.1 Acid-Base Hydrolysis of Hyaluronan 88\u003c\/p\u003e \u003cp\u003e3.5.2 Oxidation-Reduction Depolymerization of Hyaluronan 88\u003c\/p\u003e \u003cp\u003e3.6 Quality of Hyaluronan Commercial Products of Animal and Bacterial Origin 89\u003c\/p\u003e \u003cp\u003eReferences 92\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Molecular and Supramolecular Structure of Hyaluronic Acid 97\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Primary Structure of Hyaluronic Acid 97\u003c\/p\u003e \u003cp\u003e4.2 Structure of Hyaluronan in Solution 101\u003c\/p\u003e \u003cp\u003e4.3 Rheological Properties of Hyaluronic Acid 104\u003c\/p\u003e \u003cp\u003eReferences 116\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Chemical Modifications, Solid Phase, Radio-Chemical and Enzymatic Transformations of Hyaluronic Acid 121\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Main Characteristics of Cross-Linked Hydrogels 122\u003c\/p\u003e \u003cp\u003e5.2 Methods of Hyaluronic Acid Cross-Linking 124\u003c\/p\u003e \u003cp\u003e5.2.1 Cross-Linking with Carbodiimides 124\u003c\/p\u003e \u003cp\u003e5.2.2 Cross-Linking with Aldehydes 126\u003c\/p\u003e \u003cp\u003e5.2.3 Cross-Linking with Divinylsulfone 126\u003c\/p\u003e \u003cp\u003e5.2.4 Cross-Linking by the Ions of Polyvalent Metals 127\u003c\/p\u003e \u003cp\u003e5.2.5 Cross-Linking with Epoxides 127\u003c\/p\u003e \u003cp\u003e5.2.6 Photo-Cross-Linking 128\u003c\/p\u003e \u003cp\u003e5.2.7 Solid-State Cross-Linking under High Pressure and Shear Deformation (Solid-State Reactive Blending: SSRB) 130\u003c\/p\u003e \u003cp\u003e5.3 Radiochemical Transformations (Radiolysis) of Hyaluronan Aqueous Solutions 134\u003c\/p\u003e \u003cp\u003eReferences 137\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Medical Applications of Hyaluronan 143\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Hyaluronan and Aesthetic Medicine 143\u003c\/p\u003e \u003cp\u003e6.1.1 Intradermal Hyaluronan-Based Microimplants 143\u003c\/p\u003e \u003cp\u003e6.1.2 Cross-Linking of Hyaluronan into a Three-Dimensional Network 144\u003c\/p\u003e \u003cp\u003e6.1.3 Hyaluronic Acid in Injection Cosmetology (Biorevitalization) 150\u003c\/p\u003e \u003cp\u003e6.1.4 Molecular Weight of Hyaluronan in Biorevitalization Products 151\u003c\/p\u003e \u003cp\u003e6.1.5 Antioxidant Efficiency of Hyaluronan and other Biologically Active Compounds as Potential Products for Aesthetic Medicine 154\u003c\/p\u003e \u003cp\u003e6.1.6 Bio-Repairants as a New Class of Injectable Products Based on Hyaluronic Acid Modified with Low Molecular Weight Bio-Regulators 161\u003c\/p\u003e \u003cp\u003e6.2 Hyaluronan in Arthrology 170\u003c\/p\u003e \u003cp\u003e6.3 Hyaluronan in Ophthalmology 176\u003c\/p\u003e \u003cp\u003e6.4 Hyaluronan in Oncology 176\u003c\/p\u003e \u003cp\u003e6.5 The Role of Hyaluronan in Healing Wounds 183\u003c\/p\u003e \u003cp\u003e6.6 Hyaluronan in Immunology 186\u003c\/p\u003e \u003cp\u003eReferences 186\u003c\/p\u003e \u003cp\u003eConclusion 193\u003c\/p\u003e \u003cp\u003eIndex 195\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49406897815895,"sku":"9781118633793","price":98.06,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118633793.jpg?v=1730497485"},{"product_id":"iron-metabolism-9781118925614","title":"Iron Metabolism","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eIron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health.\u003cbr\u003eThe 4\u003csup\u003eth\u003c\/sup\u003e edition of \u003ci\u003eIron Metabolism\u003c\/i\u003e is written in a lively style by o\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e'This textbook is clearly a milestone which should be to hand for every researcher and scholar working on or interested in the biochemistry and clinical aspects of iron. Those needing to go further in depth on some specific aspects will find not only an excellent starting point but also their pathway through the impressive list of references at the end of each chapter.' \u003cb\u003eActa Cryst (International Union of Crystallography), November 2017\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003ePreface xii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Solution Chemistry of Iron 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Iron Chemistry 1\u003c\/p\u003e \u003cp\u003e1.2 Interactions of Iron with Dioxygen and Chemistry of Oxygen Free Radicals 2\u003c\/p\u003e \u003cp\u003e1.3 Hydrolysis of Iron Salts 5\u003c\/p\u003e \u003cp\u003e1.4 Formation and Characterisation of Ferrihydrite 7\u003c\/p\u003e \u003cp\u003e1.5 Ageing of Amorphous Ferrihydrite to more Crystalline Products 10\u003c\/p\u003e \u003cp\u003e1.6 Biomineralisation 11\u003c\/p\u003e \u003cp\u003e1.7 Magnetite Biomineralisation by Magnetotactic Bacteria 13\u003c\/p\u003e \u003cp\u003e1.7.1 Biogenesis of the Magnetosome Membrane 15\u003c\/p\u003e \u003cp\u003e1.7.2 Protein Sorting 15\u003c\/p\u003e \u003cp\u003e1.7.3 Chain Formation 16\u003c\/p\u003e \u003cp\u003e1.7.4 Biomineralisation 16\u003c\/p\u003e \u003cp\u003e1.7.5 A Model for Magnetosome Formation 17\u003c\/p\u003e \u003cp\u003eReferences 18\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 The Essential Role of Iron in Biology 22\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction: Iron an Essential Element in Biology 22\u003c\/p\u003e \u003cp\u003e2.2 Physical Techniques for the Study of Iron in Biological Systems 25\u003c\/p\u003e \u003cp\u003e2.3 Classes of Iron Proteins 29\u003c\/p\u003e \u003cp\u003e2.4 Haemoproteins 29\u003c\/p\u003e \u003cp\u003e2.4.1 Oxygen Carriers 30\u003c\/p\u003e \u003cp\u003e2.4.2 Activators of Molecular Oxygen 34\u003c\/p\u003e \u003cp\u003e2.4.3 Electron Transport Proteins 38\u003c\/p\u003e \u003cp\u003e2.5 Iron–Sulphur Proteins 41\u003c\/p\u003e \u003cp\u003e2.6 Non]haem, Non]Fe–S Proteins 48\u003c\/p\u003e \u003cp\u003e2.6.1 Mononuclear Non]haem Iron Enzymes 48\u003c\/p\u003e \u003cp\u003e2.6.1.1 Extradiol]cleaving Catechol Dioxygenases 49\u003c\/p\u003e \u003cp\u003e2.6.1.2 Rieske Oxygenases 49\u003c\/p\u003e \u003cp\u003e2.6.1.3 α]Ketoglutarate]dependent Enzymes 52\u003c\/p\u003e \u003cp\u003e2.6.1.4 Pterin]dependent Hydroxylases 54\u003c\/p\u003e \u003cp\u003e2.6.1.5 Miscellaneous Enzymes 55\u003c\/p\u003e \u003cp\u003e2.6.2 Dinuclear Non]haem Iron Proteins 55\u003c\/p\u003e \u003cp\u003e2.6.3 Proteins of Iron Storage, Transport and Metabolism 61\u003c\/p\u003e \u003cp\u003e2.7 The Dark Side of Iron: Ros , Rns and Ntbi 62\u003c\/p\u003e \u003cp\u003e2.7.1 ROS and RNS 63\u003c\/p\u003e \u003cp\u003e2.7.2 NTBI and LPI 64\u003c\/p\u003e \u003cp\u003eReferences 64\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Microbial Iron Uptake 71\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 71\u003c\/p\u003e \u003cp\u003e3.2 Iron Uptake from Siderophores 74\u003c\/p\u003e \u003cp\u003e3.2.1 Siderophores 74\u003c\/p\u003e \u003cp\u003e3.2.2 Iron Transport across the Outer Membrane in Gram]negative Bacteria 78\u003c\/p\u003e \u003cp\u003e3.2.3 Transport across the Periplasm and Cytoplasmic Membrane in Gram]negative Bacteria 86\u003c\/p\u003e \u003cp\u003e3.2.4 Iron Uptake by Gram]positive Bacteria 92\u003c\/p\u003e \u003cp\u003e3.3 Fe2+ Transport Systems 93\u003c\/p\u003e \u003cp\u003e3.4 Iron Release from Siderophores in the Cytoplasm 97\u003c\/p\u003e \u003cp\u003e3.5 Intracellular Iron Metabolism 98\u003c\/p\u003e \u003cp\u003e3.6 Control of Gene Expression by Iron 101\u003c\/p\u003e \u003cp\u003eReferences 108\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Iron Acquisition by Pathogens 120\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 120\u003c\/p\u003e \u003cp\u003e4.2 Host Defence Mechanisms, Nutritional Immunity 121\u003c\/p\u003e \u003cp\u003e4.3 Pathogenicity and PAIs 123\u003c\/p\u003e \u003cp\u003e4.4 Pathogen]specific Iron Uptake Systems 125\u003c\/p\u003e \u003cp\u003e4.4.1 Siderophores Associated with Virulence 125\u003c\/p\u003e \u003cp\u003e4.4.2 Transferrin\/lactoferrin Iron Uptake 126\u003c\/p\u003e \u003cp\u003e4.4.3 Haem Iron Uptake 133\u003c\/p\u003e \u003cp\u003e4.4.4 Ferrous Iron Uptake 138\u003c\/p\u003e \u003cp\u003e4.4.5 Ferric Citrate Uptake by Bacillus cereus 141\u003c\/p\u003e \u003cp\u003e4.5 Role of Fur and Fur Homologues in Virulence 141\u003c\/p\u003e \u003cp\u003e4.6 Role of Pathogen Ecf Sigma Factors 141\u003c\/p\u003e \u003cp\u003e4.7 Fungal Pathogens 143\u003c\/p\u003e \u003cp\u003eReferences 146\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Iron Uptake by Plants and Fungi 155\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Iron Uptake by Plants 155\u003c\/p\u003e \u003cp\u003e5.1.1 Introduction 155\u003c\/p\u003e \u003cp\u003e5.1.2 Genome Sequencing 157\u003c\/p\u003e \u003cp\u003e5.1.2.1 Quantitative Trait Loci 158\u003c\/p\u003e \u003cp\u003e5.1.3 Iron Acquisition by the Roots of Plants 160\u003c\/p\u003e \u003cp\u003e5.1.3.1 Non]graminaceous Plants 161\u003c\/p\u003e \u003cp\u003e5.1.3.2 Graminaceous Plants 164\u003c\/p\u003e \u003cp\u003e5.1.4 Long]distance Iron Transport 166\u003c\/p\u003e \u003cp\u003e5.2 Iron Metabolism and Homeostasis in Plants 169\u003c\/p\u003e \u003cp\u003e5.2.1 New Tools in Plant Research 169\u003c\/p\u003e \u003cp\u003e5.2.2 Intracellular Iron Metabolism 170\u003c\/p\u003e \u003cp\u003e5.2.3 Plant Iron Homeostasis 171\u003c\/p\u003e \u003cp\u003e5.2.4 Diurnal Regulation of Iron Homeostasis 176\u003c\/p\u003e \u003cp\u003e5.3 Iron Uptake, Metabolism and Homeostasis in Fungi 178\u003c\/p\u003e \u003cp\u003e5.3.1 Introduction 178\u003c\/p\u003e \u003cp\u003e5.3.2 High] and Low]affinity Iron Uptake Pathways 179\u003c\/p\u003e \u003cp\u003e5.3.3 Siderophore]mediated Iron Uptake 184\u003c\/p\u003e \u003cp\u003e5.3.4 Intracellular Iron Metabolism 185\u003c\/p\u003e \u003cp\u003e5.3.5 Iron Homeostasis 186\u003c\/p\u003e \u003cp\u003eReferences 190\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Cellular Iron Uptake and Export in Mammals 205\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 The Transferrins 205\u003c\/p\u003e \u003cp\u003e6.1.1 Introduction 205\u003c\/p\u003e \u003cp\u003e6.1.2 The Transferrin Family 206\u003c\/p\u003e \u003cp\u003e6.1.3 Structure of Transferrins 211\u003c\/p\u003e \u003cp\u003e6.1.4 Transferrin iron Binding 215\u003c\/p\u003e \u003cp\u003e6.1.5 Binding of other Metals by Transferrin 218\u003c\/p\u003e \u003cp\u003e6.2 Cellular Iron Uptake 219\u003c\/p\u003e \u003cp\u003e6.2.1 The Transferrin Receptors 219\u003c\/p\u003e \u003cp\u003e6.2.2 The Transferrin to Cell Cycle and Iron Release 222\u003c\/p\u003e \u003cp\u003e6.2.3 Iron Uptake from other Sources 228\u003c\/p\u003e \u003cp\u003e6.3 Cellular Iron Export 230\u003c\/p\u003e \u003cp\u003eReferences 236\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Mammalian Iron Metabolism and Dietary Iron Absorption 247\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 An overview of Mammalian Iron Metabolism 247\u003c\/p\u003e \u003cp\u003e7.1.1 Introduction 247\u003c\/p\u003e \u003cp\u003e7.1.2 The Way Different Cells Handle Iron 249\u003c\/p\u003e \u003cp\u003e7.2 Mammalian Iron Absorption 251\u003c\/p\u003e \u003cp\u003e7.2.1 Introduction 251\u003c\/p\u003e \u003cp\u003e7.2.2 The Intestinal Mucosa 252\u003c\/p\u003e \u003cp\u003e7.2.3 Sources of Dietary Iron 253\u003c\/p\u003e \u003cp\u003e7.2.4 Iron Loss and Effects on Uptake 255\u003c\/p\u003e \u003cp\u003e7.3 Molecular Mechanisms of Mucosal Iron Absorption 256\u003c\/p\u003e \u003cp\u003e7.3.1 Iron Uptake at the Apical Pole 256\u003c\/p\u003e \u003cp\u003e7.3.2 Iron Transit through and Storage in Enterocytes 259\u003c\/p\u003e \u003cp\u003e7.3.3 Iron Efflux across the Basolateral Membrane 259\u003c\/p\u003e \u003cp\u003e7.3.4 Regulation of Iron Uptake by the Enterocyte 261\u003c\/p\u003e \u003cp\u003eReferences 261\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Intracellular Iron Utilisation 265\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Intracellular Iron Pools 265\u003c\/p\u003e \u003cp\u003e8.1.1 Introduction 265\u003c\/p\u003e \u003cp\u003e8.1.2 The Cytosolic Labile Iron Pool (LIP) 266\u003c\/p\u003e \u003cp\u003e8.1.3 Distribution of Iron in the Cytosol 268\u003c\/p\u003e \u003cp\u003e8.1.4 Other Intracellular Iron Pools 269\u003c\/p\u003e \u003cp\u003e8.2 Mitochondrial Iron Metabolism 271\u003c\/p\u003e \u003cp\u003e8.2.1 Mitochondrial Iron Uptake and Storage 271\u003c\/p\u003e \u003cp\u003e8.2.2 Mitochondrial Fe–S Protein Biogenesis 271\u003c\/p\u003e \u003cp\u003e8.2.3 Maturation of Cytosolic and Nuclear Fe–S Proteins 275\u003c\/p\u003e \u003cp\u003e8.2.4 Haem Biosynthesis 283\u003c\/p\u003e \u003cp\u003e8.3 Haem Oxygenase 287\u003c\/p\u003e \u003cp\u003e8.3.1 Structure and Catalytic Cycle 287\u003c\/p\u003e \u003cp\u003e8.3.2 Activation of Haem Oxygenase 1 (HO]1) 292\u003c\/p\u003e \u003cp\u003eReferences 292\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Iron Storage Proteins 300\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 300\u003c\/p\u003e \u003cp\u003e9.2 The Ferritin Superfamily and Haemosiderins 301\u003c\/p\u003e \u003cp\u003e9.2.1 The Ferritin Superfamily 301\u003c\/p\u003e \u003cp\u003e9.2.2 Structure of Vertebrate and Invertebrate Ferritins 304\u003c\/p\u003e \u003cp\u003e9.2.3 Plant and Bacterial Ferritins 308\u003c\/p\u003e \u003cp\u003e9.2.4 Dps Proteins and Rubrerythrins 313\u003c\/p\u003e \u003cp\u003e9.2.5 The Mineral Core 319\u003c\/p\u003e \u003cp\u003e9.2.6 Haemosiderins 319\u003c\/p\u003e \u003cp\u003e9.3 Iron Uptake and Release from Ferritin 320\u003c\/p\u003e \u003cp\u003e9.3.1 Iron Uptake in Ferritins 320\u003c\/p\u003e \u003cp\u003e9.3.1.1 Entry of Fe(II) into the Protein Shell 321\u003c\/p\u003e \u003cp\u003e9.3.1.2 Oxidation of Fe2+ by Ferroxidase Sites 323\u003c\/p\u003e \u003cp\u003e9.3.1.3 Mineralisation of the Iron Core 325\u003c\/p\u003e \u003cp\u003e9.3.2 Iron Uptake in Dps Proteins 333\u003c\/p\u003e \u003cp\u003e9.3.3 Iron Release from Ferritin 333\u003c\/p\u003e \u003cp\u003e9.4 Biotechnological Applications of Ferritins 335\u003c\/p\u003e \u003cp\u003eReferences 336\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Cellular and Systemic Iron Homeostasis 346\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Cellular Iron Homeostasis 346\u003c\/p\u003e \u003cp\u003e10.1.1 Translational Control of Protein Synthesis 346\u003c\/p\u003e \u003cp\u003e10.1.2 The IRE\/IRP System 347\u003c\/p\u003e \u003cp\u003e10.1.3 The IREs – distribution and Structure 348\u003c\/p\u003e \u003cp\u003e10.1.4 Structural Features of IRP1 and 2 351\u003c\/p\u003e \u003cp\u003e10.1.5 The IRE\/IRP System Revisited – Iron Controls Iron 353\u003c\/p\u003e \u003cp\u003e10.1.6 Metabolic Consequences of Mutations in Ires 357\u003c\/p\u003e \u003cp\u003e10.2 Systemic Iron Homeostasis 357\u003c\/p\u003e \u003cp\u003e10.2.1 Introduction 357\u003c\/p\u003e \u003cp\u003e10.2.2 Hepcidin, the Key Player 358\u003c\/p\u003e \u003cp\u003e10.2.3 Factors which Regulate Hepcidin Synthesis 360\u003c\/p\u003e \u003cp\u003e10.2.3.1 Iron Availability 361\u003c\/p\u003e \u003cp\u003e10.2.3.2 Inflammatory Stimuli 364\u003c\/p\u003e \u003cp\u003e10.2.3.3 Erythropoietic Demand 364\u003c\/p\u003e \u003cp\u003e10.2.3.4 Hypoxia 365\u003c\/p\u003e \u003cp\u003e10.2.3.5 Endocrine Signals 366\u003c\/p\u003e \u003cp\u003e10.3 Integration of Iron Homeostatic Systems 367\u003c\/p\u003e \u003cp\u003eReferences 367\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Iron Deficiency, Iron Overload and Therapy 376\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Iron]deficiency Anaemia (Ida) 376\u003c\/p\u003e \u003cp\u003e11.1.1 Introduction – The Size of the Problem 376\u003c\/p\u003e \u003cp\u003e11.1.2 Causes of Ida 378\u003c\/p\u003e \u003cp\u003e11.1.3 Clinical Stages and Diagnosis of Ida 380\u003c\/p\u003e \u003cp\u003e11.1.4 Therapeutic Approaches 383\u003c\/p\u003e \u003cp\u003e11.1.5 Anaemia of Chronic Disease (Acd ), Iron Refractory Ida (Irida ) and Anaemia of Chronic Kidney Disease (Ckd) 384\u003c\/p\u003e \u003cp\u003e11.2 Hereditary Iron Overload 386\u003c\/p\u003e \u003cp\u003e11.2.1 Introduction 386\u003c\/p\u003e \u003cp\u003e11.2.2 Hereditary Haemochromatosis (Hh) 386\u003c\/p\u003e \u003cp\u003e11.2.3 Causes of HH 387\u003c\/p\u003e \u003cp\u003e11.2.4 Types of Haemochromatosis 388\u003c\/p\u003e \u003cp\u003e11.2.4.1 Hfe]related (Type 1) Haemochromatosis 388\u003c\/p\u003e \u003cp\u003e11.2.4.2 Juvenile (Type 2) Haemochromatosis 390\u003c\/p\u003e \u003cp\u003e11.2.4.3 Tfr2]related (Type 3) Haemochromatosis 390\u003c\/p\u003e \u003cp\u003e11.2.4.4 Ferroportin Disease 390\u003c\/p\u003e \u003cp\u003e11.2.5 Therapy of Hereditary Haemochromatosis 391\u003c\/p\u003e \u003cp\u003e11.3 Acquired Iron Overload 395\u003c\/p\u003e \u003cp\u003e11.3.1 Introduction – Causes of Acquired Iron Overload 395\u003c\/p\u003e \u003cp\u003e11.3.2 Mechanisms of Iron Toxicity 397\u003c\/p\u003e \u003cp\u003e11.3.3 Evaluation of Iron Overload 398\u003c\/p\u003e \u003cp\u003e11.3.4 Chelation Therapy for Acquired Iron Overload 400\u003c\/p\u003e \u003cp\u003e11.3.5 Other Therapeutic Approaches 405\u003c\/p\u003e \u003cp\u003eReferences 406\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Iron and Immunity 418\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 418\u003c\/p\u003e \u003cp\u003e12.1.1 Innate Immunity 419\u003c\/p\u003e \u003cp\u003e12.2 The Key Role of Macrophages 422\u003c\/p\u003e \u003cp\u003e12.2.1 Overview 422\u003c\/p\u003e \u003cp\u003e12.2.2 Macrophage Phenotypes 425\u003c\/p\u003e \u003cp\u003e12.2.3 Microglia 426\u003c\/p\u003e \u003cp\u003e12.3 Effect of Iron Status on Phagocytic Cell Function 429\u003c\/p\u003e \u003cp\u003e12.3.1 Iron Deficiency 429\u003c\/p\u003e \u003cp\u003e12.3.2 Iron Overload 430\u003c\/p\u003e \u003cp\u003e12.4 Effect of Phagocytic Cell Function on Iron Metabolism 431\u003c\/p\u003e \u003cp\u003e12.4.1 The IRE–Iron Regulatory Protein (IRP) System 431\u003c\/p\u003e \u003cp\u003e12.5 Effector Molecules of the Innate Immune System 433\u003c\/p\u003e \u003cp\u003e12.5.1 Toll]like Receptors 433\u003c\/p\u003e \u003cp\u003e12.5.2 NF]κB 433\u003c\/p\u003e \u003cp\u003e12.5.3 Hypoxia]Inducible Factor 1 (Hif 1) 434\u003c\/p\u003e \u003cp\u003e12.5.4 Haem Oxygenase 435\u003c\/p\u003e \u003cp\u003e12.5.5 DMT1, Nramp1 437\u003c\/p\u003e \u003cp\u003e12.6 Adaptive Immunity 437\u003c\/p\u003e \u003cp\u003e12.6.1 Cd8+ Lymphocytes and Cytotoxicity 438\u003c\/p\u003e \u003cp\u003e12.6.2 CD4+ lymphocytes 438\u003c\/p\u003e \u003cp\u003e12.7 Immune Function and other Factors 438\u003c\/p\u003e \u003cp\u003e12.7.1 Iron Supplementation and Immune Function 438\u003c\/p\u003e \u003cp\u003e12.7.2 Immune Function in the Elderly Population 439\u003c\/p\u003e \u003cp\u003e12.7.3 Iron Overload and Immune Function 439\u003c\/p\u003e \u003cp\u003e12.7.4 Thalassaemia 440\u003c\/p\u003e \u003cp\u003e12.8 Concluding Remarks 440\u003c\/p\u003e \u003cp\u003eReferences 440\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Iron and Oxidative Stress 444\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Oxidative stress 444\u003c\/p\u003e \u003cp\u003e13.1.1 Introduction – Milestones in the History of Life 444\u003c\/p\u003e \u003cp\u003e13.1.2 Reactive Oxygen Species (Ros ) and Reactive Nitrogen Species (Rns) 447\u003c\/p\u003e \u003cp\u003e13.1.3 Cellular Defence Mechanisms Against Oxidative Stress 450\u003c\/p\u003e \u003cp\u003e13.1.4 Role of ROS and RNS in Cell Signalling 460\u003c\/p\u003e \u003cp\u003e13.1.5 ROS, RNS and Oxidative Damage 466\u003c\/p\u003e \u003cp\u003eReferences 476\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Interactions between Iron and other Metals 482\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction 482\u003c\/p\u003e \u003cp\u003e14.2 Iron Interactions with Essential Metals 483\u003c\/p\u003e \u003cp\u003e14.2.1 Copper 483\u003c\/p\u003e \u003cp\u003e14.2.1.1 Introduction 483\u003c\/p\u003e \u003cp\u003e14.2.1.2 Copper Acquisition and Metabolism 485\u003c\/p\u003e \u003cp\u003e14.2.1.3 Copper Chaperones 486\u003c\/p\u003e \u003cp\u003e14.2.1.4 Iron–copper Interactions 487\u003c\/p\u003e \u003cp\u003e14.2.2 Zinc 494\u003c\/p\u003e \u003cp\u003e14.2.2.1 Introduction 494\u003c\/p\u003e \u003cp\u003e14.2.2.2 Iron–zinc Interactions 496\u003c\/p\u003e \u003cp\u003e14.2.3 Cobalt 497\u003c\/p\u003e \u003cp\u003e14.2.3.1 Introduction 497\u003c\/p\u003e \u003cp\u003e14.2.3.2 Iron–cobalt Interactions 498\u003c\/p\u003e \u003cp\u003e14.2.4 Manganese 500\u003c\/p\u003e \u003cp\u003e14.2.4.1 Iron–manganese Interactions 500\u003c\/p\u003e \u003cp\u003e14.2.5 Calcium 501\u003c\/p\u003e \u003cp\u003e14.2.5.1 Iron–calcium Interactions 501\u003c\/p\u003e \u003cp\u003e14.3 Iron Interactions with Toxic Metals 502\u003c\/p\u003e \u003cp\u003e14.3.1 Lead 502\u003c\/p\u003e \u003cp\u003e14.3.2 Cadmium 503\u003c\/p\u003e \u003cp\u003e14.3.3 Aluminium 505\u003c\/p\u003e \u003cp\u003eReferences 507\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Iron Homeostasis and Neurodegeneration 516\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction 516\u003c\/p\u003e \u003cp\u003e15.2 Brain iron 517\u003c\/p\u003e \u003cp\u003e15.2.1 Brain Iron Homeostasis 517\u003c\/p\u003e \u003cp\u003e15.2.2 Aging and Brain Iron Content 518\u003c\/p\u003e \u003cp\u003e15.3 Iron and Neurodegeneration 522\u003c\/p\u003e \u003cp\u003e15.3.1 Introduction 522\u003c\/p\u003e \u003cp\u003e15.3.2 Adverse Effects of Iron in Neurodegeneration 522\u003c\/p\u003e \u003cp\u003e15.3.2.1 Toxicity of ROS and RNS 522\u003c\/p\u003e \u003cp\u003e15.3.2.2 Iron and Mitochondrial Function 523\u003c\/p\u003e \u003cp\u003e15.3.2.3 Protein Aggregation 523\u003c\/p\u003e \u003cp\u003e15.4 Neurodegeneration with Brain Iron Accumulation 524\u003c\/p\u003e \u003cp\u003e15.4.1 Aceruloplasminaemia 524\u003c\/p\u003e \u003cp\u003e15.4.2 Neuroferritinopathy 526\u003c\/p\u003e \u003cp\u003e15.4.3 Other NBIAs 528\u003c\/p\u003e \u003cp\u003e15.5 Other Monogenic Neurodegenerative Diseases 530\u003c\/p\u003e \u003cp\u003e15.5.1 Huntington’s Disease 530\u003c\/p\u003e \u003cp\u003e15.5.2 Friedreich’s Ataxia 532\u003c\/p\u003e \u003cp\u003e15.6 Neurodegeneration Involving Multiple Genes 533\u003c\/p\u003e \u003cp\u003e15.6.1 Parkinson’s Disease (PD) 533\u003c\/p\u003e \u003cp\u003e15.6.2 Alzheimer’s Disease (AD) 535\u003c\/p\u003e \u003cp\u003e15.6.3 Multiple Sclerosis (MS) 537\u003c\/p\u003e \u003cp\u003e15.7 Intracerebral Haemorrhage 538\u003c\/p\u003e \u003cp\u003eReferences 539\u003c\/p\u003e \u003cp\u003eConcluding Remarks 544\u003c\/p\u003e \u003cp\u003eIndex 547\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49406948245847,"sku":"9781118925614","price":133.16,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118925614.jpg?v=1730497657"},{"product_id":"endocrine-and-metabolic-medical-emergencies-9781119374732","title":"Endocrine and Metabolic Medical Emergencies","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eThe Essential Guide to Recognizing and Treating Acute Endocrine and Metabolic Illness\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eEndocrinology covers some of the most common conditions and serious public health challenges facing medicine today, and endocrine and metabolic emergencies constitute a large proportion of the clinical workload. \u003ci\u003eEndocrine and Metabolic Medical Emergencies: A Clinician's Guide\u003c\/i\u003e provides a singular reference to help endocrinologists, acute and general medicine clinicians, hospitalists and critical care physicians, and general practitioners recognize the symptoms of endocrine emergencies and provide the highest standards of care. Already the definitive and most comprehensive guide to endocrine emergency care, this new second edition: provides acute care guidance for a range of both common and unusual endocrine emergencies; details the effects of acute medical and critical illness on metabolic and endocrine systems, and their impacts on endocrine investigations; discusses special pa\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eNotes on Contributors x\u003c\/p\u003e \u003cp\u003eForeword xv\u003c\/p\u003e \u003cp\u003ePreface xvi\u003c\/p\u003e \u003cp\u003eList of Abbreviations xviii\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I General Aspects of AcuteMedical Emergencies 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: AcuteMedical Care: A Crisis with Solutions 3\u003cbr\u003e\u003ci\u003eGlennMatfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1 Early Management of AcuteMedical Emergencies 10\u003cbr\u003e\u003ci\u003ePaul J. Frost and Matt P.Wise\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II General Endocrine and Metabolic Aspects of Acute and Critical Illness 21\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Endocrine Testing and Responses in Acute and Critical Illness 23\u003cbr\u003e\u003ci\u003eDavid B. Sacks\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Endocrine Testing in Acute and Critical Illness 28\u003cbr\u003e\u003ci\u003eReza Morovat\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Endocrine Responses to Critical Illness: Novel Insights and Therapeutic Implications 60\u003cbr\u003e\u003ci\u003eJan Gunst, Eva Boonen, and Greet Van den Berghe\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Special Populations 83\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4 Endocrine and Metabolic Emergencies in Pregnancy 85\u003cbr\u003e\u003ci\u003eAnita Banerjee and CatherineWilliamson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Endocrine and Metabolic Emergencies in Inherited Metabolic Diseases: Acute Presentations in Adulthood 98\u003cbr\u003e\u003ci\u003eElaine Murphy and Robin H. Lachmann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Endocrine and Metabolic Emergencies in Transitional Care 110\u003cbr\u003e\u003ci\u003eMabel Yau andMark A. Sperling\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7Emergency Perioperative Diabetes and Endocrine Management 129\u003cbr\u003e\u003ci\u003eGlenn Matfin, Kate Evans, and Ketan Dhatariya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Endocrine and Metabolic Emergencies in HIV\/AIDS 151\u003cbr\u003e\u003ci\u003eKatherine Samaras\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Endocrine and Metabolic Emergencies in Late-Effects Patients: Consequences of Cancer Therapy 160\u003cbr\u003e\u003ci\u003eHelena Gleeson and Andrew Toogood\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Endocrine and Metabolic Emergencies in Transplantation 171\u003cbr\u003e\u003ci\u003eRobert A. Wermers and Pankaj Shah\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Endocrine and Metabolic Changes with Aging: Endocrin-Aging: Recognizing and Managing Care in Older Frail Persons 182\u003cbr\u003e\u003ci\u003eAngela M. Abbatecola and John E.Morley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Pituitary Disorders 195\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Pituitary Disorders 197\u003cbr\u003e\u003ci\u003eEdward R. Laws and Ursula B. Kaiser\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Hypopituitarism 203\u003cbr\u003e\u003ci\u003eNicholas A. Tritos and Anne Klibanski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Pituitary Apoplexy 218\u003cbr\u003e\u003ci\u003eClaire Briet and Philippe Chanson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Macroprolactinomas 231\u003cbr\u003e\u003ci\u003eMark E. Molitch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V Thyroid Disorders 243\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Thyroid Disorders 245\u003cbr\u003e\u003ci\u003eHossein Gharib\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Myxedema Coma 252\u003cbr\u003e\u003ci\u003eNatasha Kasid and James V. Hennessey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Life-Threatening Thyrotoxicosis: Thyroid Storm and Adverse Effects of Antithyroid Drugs 262\u003cbr\u003e\u003ci\u003eAlicia L.Warnock, David S. Cooper, and Henry B. Burch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Amiodarone-Induced Thyrotoxicosis 284\u003cbr\u003e\u003ci\u003eFausto Bogazzi, Luca Tomisti, Luigi Bartalena, and Enio Martino\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Thyrotoxic Periodic Paralysis 296\u003cbr\u003e\u003ci\u003eMark Vanderpump\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Sight-Threatening Graves’Orbitopathy 305\u003cbr\u003e\u003ci\u003eRebecca S. Bahn and James A. Garrity\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VI Adrenal Disorders 313\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Adrenal Disorders 315\u003cbr\u003e\u003ci\u003eAnand Vaidya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Acute Adrenal Insufficiency 321\u003cbr\u003e\u003ci\u003eGlenn Matfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Acute Medical Aspects Related to Florid Cushing’s Syndrome 345\u003cbr\u003e\u003ci\u003eKrystallenia I. Alexandraki and Ashley B. Grossman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Endocrine Hypertensive Emergencies 355\u003cbr\u003e\u003ci\u003eGraeme Eisenhofer, Andrzej Januszewicz, Christina Pamporaki, and Jacques W. M. Lenders\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VII Calcium, Phosphate, and Metabolic Bone Diseases 375\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Calcium, Phosphate, and Metabolic Bone Diseases 377\u003cbr\u003e\u003ci\u003eJohn P. Bilezikian\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Hypocalcemia 380\u003cbr\u003e\u003ci\u003eGlenn Matfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Hypercalcemia 400\u003cbr\u003e\u003ci\u003eGlenn Matfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 Acute Medical Aspects Related to Phosphate Disorders 422\u003cbr\u003e\u003ci\u003eAnda R. Gonciulea and Suzanne M. Jan de Beur\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Acute Medical Aspects Related to Osteoporosis and Its Therapy 433\u003cbr\u003e\u003ci\u003eDima L. Diab and Nelson B.Watts\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Acute Medical Aspects Related to Paget’s Disease of Bone 447\u003cbr\u003e\u003ci\u003eEthel S. Siris and Dorothy A. Fink\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Acute Medical Aspects Related to Kidney Stones 454\u003cbr\u003e\u003ci\u003eHasan Fattah and David S. Goldfarb\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VIII Neuroendocrine Tumors 465\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Neuroendocrine Tumors 467\u003cbr\u003e\u003ci\u003eKjell Oberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Acute Endocrine and Metabolic Emergencies Related to Neuroendocrine Tumors 472\u003cbr\u003e\u003ci\u003eGregory Kaltsas, Krystallenia I. Alexandraki, and Ashley B. Grossman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IX Glucose Disorders 485\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Glucose Disorders 487\u003cbr\u003e\u003ci\u003eGerry Rayman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Management of Diabetes and\/or Hyperglycemia in Non-Critical Care Hospital Settings 491\u003cbr\u003e\u003ci\u003eRodolfo J. Galindo and Guillermo E. Umpierrez\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Hypoglycemia 506\u003cbr\u003e\u003ci\u003eElizabeth M. Lamos, Lisa M. Younk, and Stephen N. Davis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 Severe Hyperglycemia, Diabetic Ketoacidosis, and Hyperglycemic Hyperosmolar State 531\u003cbr\u003e\u003ci\u003eKetan Dhatariya and GlennMatfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 Short-Term Intensive Insulin Therapy in Patients with Newly Presenting Type Diabetes 548\u003cbr\u003e\u003ci\u003eWen Xu, David Owens, and JianpingWeng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Management of Concentrated Insulins in Acute Care Settings 560\u003cbr\u003e\u003ci\u003eNuha El Sayed, Megan J. Ritter, and Alissa R. Segal\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Management of Insulin Pumps in Hospitalized Patients 571\u003cbr\u003e\u003ci\u003eBithika M. Thompson, Patricia A. Mackey, and Curtiss B. Cook\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e36 Management of Diabetes and\/or Hyperglycemia during Enteral and Parenteral Nutrition 584\u003cbr\u003e\u003ci\u003eAidar R. Gosmanov and Niyaz R. Gosmanov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e37 Management of Diabetes and\/or Hyperglycemia in Hospitalized Patients with Renal Insufficiency 598\u003cbr\u003e\u003ci\u003eGlenn Matfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e38 Management of Glucocorticoid-Induced Diabetes and\/or Hyperglycemia 616\u003cbr\u003e\u003ci\u003eHan Na Kim and NestorasMathioudakis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e39 Management of Diabetes and\/or Hyperglycemia in Acute Coronary Syndrome, Acute Stroke, and Acute Heart Failure 632\u003cbr\u003e\u003ci\u003eMiles Fisher\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e40 Acute Diabetic Foot 648\u003cbr\u003e\u003ci\u003eGlenn Matfin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart X Sodium Disorders 673\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management of Sodium Disorders 675\u003cbr\u003e\u003ci\u003eRichard H. Sterns\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e41 Emergency Management of Acute and Chronic Hyponatremia 679\u003cbr\u003e\u003ci\u003eJoseph G. Verbalis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e42 Emergency Management of Acute and Chronic Hypernatremia 700\u003cbr\u003e\u003ci\u003eAoife Garrahy and Christopher Thompson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart XI Obesity and Clinical Lipidology 717\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIntroduction: Emergency Management Related to Obesity and Clinical Lipidology 719\u003cbr\u003e\u003ci\u003eRobert H. Eckel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e43 Acute Emergencies Related to Bariatric Surgery 723\u003cbr\u003e\u003ci\u003eMichael A. Via and Jeffrey I. Mechanick\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e44 Chylomicronemia Syndrome: Very Severe Hypertriglyceridemia and Acute Pancreatitis 742\u003cbr\u003e\u003ci\u003eAnthony S. Wierzbicki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e45 Statin-Related Myopathy and Rhabdomyolysis 760\u003cbr\u003e\u003ci\u003eConnie B. Newman and Jonathan A. Tobert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 775\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":49407040913751,"sku":"9781119374732","price":144.85,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119374732.jpg?v=1730497972"},{"product_id":"nutrition-in-crisis-flawed-studies-misleading-advice-and-the-real-science-of-human-metabolism-9781603588195","title":"Nutrition in Crisis: Flawed Studies, Misleading","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eAlmost every day it seems a new study is published that shows you are at risk for diabetes, cardiovascular disease, or death due to something you’ve just eaten for lunch. Many of us no longer know what to eat or who to believe. In Nutrition in Crisis distinguished biochemist Richard Feinman, PhD, cuts through the noise, explaining the intricacies of nutrition and human metabolism in accessible terms. He lays out the tools you need to navigate the current confusion in medical literature and its increasingly bizarre reflection in the media.\u003c\/p\u003e  \u003cp\u003eAt the same time, Nutrition in Crisis offers an unsparing critique of the nutritional establishment, which continues to demonize fat and refute the benefits of low-carbohydrate and ketogenic diets—all despite decades of evidence to the contrary. Feinman tells the story of the first low-carbohydrate revolution fifteen years ago, how it began, what killed it, and why a second revolution is now reaching a fever pitch. He exposes the backhanded tactics of a regressive nutritional establishment that ignores good data and common sense, and highlights the innovative work of those researchers who have broken rank.\u003c\/p\u003e  \u003cp\u003eEntertaining, informative, and irreverent, Feinman paints a broad picture of the nutrition world: the beauty of the underlying biochemistry; the embarrassing failures of the medical establishment; the preeminence of low-carbohydrate diets for weight loss, diabetes, other metabolic diseases, and even cancer; and what’s wrong with the constant reports that the foods we’ve been eating for centuries represent a threat rather than a source of pleasure.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e“In his wonderful book \u003cem\u003eNutrition in Crisis\u003c\/em\u003e, Dr. Feinman is speaking as a proper doctor should. He is looking for the \u003cem\u003ewhy\u003c\/em\u003e and \u003cem\u003ehow\u003c\/em\u003e of disease. Doctors should provide the interface between the pure science and research and the clinical art of treating patients. Indeed the word ‘doctor’ comes from the Greek ‘to teach.’ In this book Feinman leads us down a simple, logical, irrefutable path to the cause of many diseases affecting Westerners. He details the dishonest and fraudulent misinterpretation of science promulgated by Big Pharma and designed to mislead us toward prescription drug dependence. This represents unsustainable medicine for big profit. And yes, this is killing people.\u003c\/p\u003e  \u003cp\u003eMaking the lifestyle and nutritional changes necessary for lasting health is difficult. This book supplies the intellectual imperative to take control of your own health without resorting to symptom-suppressing medication. Read it, learn \u003cem\u003ewhat\u003c\/em\u003e you need to do, and you will be mentally empowered and physically fortified for life!”\u003cstrong\u003e—Dr. Sarah Myhill, author of \u003cem\u003eSustainable Medicine \u003c\/em\u003eand \u003cem\u003eDiagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“Dr. Feinman has spent his professional life dedicated to exposing the many flaws found in most reporting in nutrition science. \u003cem\u003eNutrition in Crisis\u003c\/em\u003e walks the reader through the fog of dubious statistical analysis and into the light of day. In doing so Dr. Feinman examines the science behind the low-carb debate, using humor and metaphor to engage the reader in the process.”\u003cstrong\u003e—Miriam Kalamian, EdM, MS, CNS, author of \u003cem\u003eKeto for Cancer\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“I’ve had the honor and privilege of knowing and working with Dr. Feinman for many years. I’ve watched him employ his deep knowledge of biochemistry and metabolism to tackle the entrenched, misguided nutritional advice cemented by thirty-five years of the food pyramid. His book says it all.”\u003cstrong\u003e—Eugene Fine, professor, Department of Radiology, Albert Einstein College of Medicine\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“A distinctively insightful treatise on the sad state of affairs in nutrition written by one of the true thought leaders. In his unique Brooklyn style, teacher and intellectual Dr. Richard Feinman fights against ignorance by enlightening people on the real science and application of nutrition.”\u003cstrong\u003e—Jeff S. Volek, professor, Department of Human Sciences, Ohio State University\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“Low-carb? Low-fat? Count your calories? If you have whiplash from trying to follow contradictory health headlines, you’re not alone. We’ve gotten ourselves into quite a nutritional mess thanks to poorly done research that was even more poorly reported to the public. With his trademark wry humor, Dr. Feinman exposes just how shoddy much of the research has been and outlines how to take control of your own health.”\u003cstrong\u003e—Amy Berger, MS, CNS, NTP, author of \u003cem\u003eThe Alzheimer’s Antidote\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“I was first drawn to Professor Feinman through his prolific peer reviewed publications in nutrition and metabolism. He has been a leading pioneer in educating the academic community and lay public on the health benefits of low-carbohydrate and ketogenic diets. His work was a guiding light that inspired our lab to shift focus from drug-based research to metabolic-based therapies for neurological disorders and cancer. In addition to being a fantastic comprehensive review of practical nutritional biochemistry, this book tells an informative and entertaining story about what went wrong in the nutrition establishment and advocates for a rational solution to the problem.”\u003cstrong\u003e—Dominic D’Agostino, PhD, leading scientist on ketogenic metabolic therapies\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“I have devoted my medical career to normalizing blood sugars in people with diabetes. This is only possible with very low carbohydrate diets. Dr. Feinman explains why low-carb is wise even for people without diabetes. This can’t-put-it-down title is the closest thing to a complete, popular analysis of the biochemistry of human nutrition that you will find and a superb lesson in how scientific studies have been manipulated to prove fiction.”\u003cstrong\u003e—Richard K. Bernstein, MD, FACN, FACE, CWS, author of \u003cem\u003eDr. Bernstein’s Diabetes Solution \u003c\/em\u003eand \u003cem\u003eThe Diabetes Diet\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“As a physician who has worked with thousands of patients unraveling the mysteries and mythology around diet and nutrition, it is refreshing and timely to come across a sane voice among the misinformation perpetuated by a misaligned food industry. We have moved far beyond the simple ‘calorie in, calorie out’ mentality and can now embrace biochemical individuality and updated research while avoiding the dogma of certain dietary camps.”\u003cstrong\u003e—Nasha Winters, ND, FABNO, author of \u003cem\u003eThe Metabolic Approach to Cancer\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“Every scientific discipline needs a Dr. Richard David Feinman. He is just as skeptical about what he believes as what he disbelieves. His writing bears eloquent testimony to why he is such a scientific treasure.”\u003cstrong\u003e—Timothy Noakes, MD, PhD, emeritus professor, University of Cape Town; founder, The Noakes Foundation\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“We have arrived at the most important nutritional crossroads in all of human history: We must choose to either keep the dietary status quo despite every bit of evidence that it has failed, or demand a change in order to salvage what is left of our collective health. In \u003cem\u003eNutrition in Crisis\u003c\/em\u003e, Dr. Richard Feinman has dropped the opening salvo in what is sure to be a battle for the ages—one that determines the future of how we eat and the prevalence of disease in the years to come. Join the revolution!”\u003cstrong\u003e—Jimmy Moore, health podcaster; bestselling author of \u003cem\u003eKeto Clarity\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“With his usual cutting wit and verve, Dr. Feinman hacks through the tangled thicket of nutritional science to show us how we got to the sorry state we find ourselves in today. Obesity is at an all-time high, and diabetes has soared to epidemic proportions, yet the nutritional establishment, blind to its failures, continues to exhort us to trudge down the same path that got us to this pitiful mess in the first place. Dr. Feinman teaches us how to escape. He deploys his vast experience in biochemistry, nutrition, and the turgid mindset of academia to demystify mainstream nutritional research and explain how it has currently gone off the rails. With a sprinkling of humor and literary allusions, along with a deep dive into some of the nutritional literature, he tells readers what they need to know to shed excess body fat, lower blood sugar, and restore their health. A must read for anyone with a serious interest in health and nutrition.”\u003cstrong\u003e—Michael R. Eades, MD, author of \u003cem\u003eProtein Power\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e“Fascinating book, full of original, interesting material by one of the original low-carb researchers whose grounding in the field goes back decades. Feinman combines a unique perspective with the experienced eye of a scientist. He’s had a front row seat to developments in the field of carbohydrates and metabolism over the past decades, which has given him key insights into the latest research.”\u003cstrong\u003e—Nina Teicholz, author of \u003cem\u003eThe Big Fat Surprise\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Chelsea Green Publishing Co","offers":[{"title":"Default Title","offer_id":49410538537303,"sku":"9781603588195","price":18.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781603588195.jpg?v=1730510477"},{"product_id":"lymphedema-management-the-comprehensive-guide-for-practitioners-9781626234338","title":"Lymphedema Management: The Comprehensive Guide","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFIVE STARS from Doody's Star Ratings™\u003c\/strong\u003e\u003c\/p\u003e \u003cp\u003eThis essential guide encompasses the core principles of Manual Lymph Drainage and Complete Decongestive Therapy for a wide range of pathologies across the age continuum. Key elements from the prior edition are incorporated, such as color-coded sections for anatomy, physiology, and pathophysiology. Advances in the field are reflected in expanded chapters and efficacy meta-analyses, updates on genetics, refinements in manual compression, and new insights on fat disorders and edema.\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eKey highlights in fourth edition\u003c\/strong\u003e\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003eMore than 140 new color images, over 30 new tables, and updated ICD-10 codes\u003c\/li\u003e\n\u003cli\u003eExpanded discussion of lipedema and related conditions such as Dercum's and Madelung's diseases\u003c\/li\u003e\n\u003cli\u003eSurgical approaches such as vascularized lymph node transfer, anastomosis and bypass techniques, suction assisted protein lipectomy, and combined and staged lymphedema operations\u003c\/li\u003e\n\u003cli\u003eWound care options for edema and advanced venous disease\u003c\/li\u003e\n\u003cli\u003eIntegration of conventional therapies and techniques in collaboration with surgeons who perform specialized lymphatic procedures\u003c\/li\u003e\n\u003cli\u003eTips and guidance for growing numbers of home care focused practitioners who encounter lymphedema and related edemas in patients\u003c\/li\u003e\n\u003cli\u003eManagement of garments including fit, functionality, and patient independence\u003c\/li\u003e\n\u003cli\u003eRare pediatric syndromes and adaption of CDT for children\u003c\/li\u003e\n\u003cli\u003eExpanded discussion of sequential intermittent pneumatic compression including contraindications and usages in lymphedema management\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThis is a must-have resource on the diagnosis, treatment, and management of lymphedema and lymphatic insufficiency. Its unique practicality will enable educators to teach techniques and clinicians to adeptly incorporate a wide range of treatment strategies into practice.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e1 Anatomy\u003cbr\u003e 2 Physiology\u003cbr\u003e 3 Pathology\u003cbr\u003e 4 Complete Decongestive Therapy\u003cbr\u003e 5 Treatment\u003cbr\u003e 6 Administration\u003c\/p\u003e","brand":"Thieme Medical Publishers Inc","offers":[{"title":"Default Title","offer_id":49410743042391,"sku":"9781626234338","price":68.88,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781626234338.jpg?v=1730511207"},{"product_id":"the-power-of-hormones-9781668057889","title":"The Power of Hormones","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"S\u0026s\/Simon Element","offers":[{"title":"Default Title","offer_id":49411279094103,"sku":"9781668057889","price":18.24,"currency_code":"GBP","in_stock":true}]},{"product_id":"metabolomics-and-systems-biology-in-human-health-and-medicine-9781780642000","title":"Metabolomics and Systems Biology in Human Health","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe metabolomics and systems biology approach to research can be applied to many disciplines. This book provides a solid introduction to medical metabolomics and systems biology, and demonstrates how they have been applied to studies in medicine and human health, including nutrition and pathogenic microorganisms. Following core themes of diagnosis, pathology and aetiology of disease, this book provides a reference for health care professionals interested in how to use metabolomics for medical research.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ea: Foreword 1: An Introduction to Metabolomics and Systems Biology 2: Metabolomics in Neuroscience and Neurology 3: Cardiovascular Disease and Health 4: Chronic Obstructive Pulmonary Disease (COPD) and Metabolomics 5: In Search of New Biomarkers for Liver Diseases 6: Influences Shaping Digestive Health Explored Using Metabolomics 7: Applications of Metabolomics in the Study of Pathogenic Microorganisms and Their Effects on Human Health 8: Type 2 Diabetes Mellitus and The Metabolic Syndrome 9: Biomarkers of Skeletal Muscle Regulation, Metabolism and Dysfunction 10: Applications of Metabolomics in Cancer Research","brand":"CABI Publishing","offers":[{"title":"Default Title","offer_id":49411776119127,"sku":"9781780642000","price":88.92,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781780642000.jpg?v=1730514648"},{"product_id":"metabolomics-and-systems-biology-in-human-health-and-medicine-9781786395429","title":"Metabolomics and Systems Biology in Human Health","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe metabolomics and systems biology approach to research can be applied to many disciplines. This book provides a solid introduction to medical metabolomics and systems biology, and demonstrates how they have been applied to studies in medicine and human health, including nutrition and pathogenic microorganisms. Following core themes of diagnosis, pathology and aetiology of disease, this book provides a reference for health care professionals interested in how to use metabolomics for medical research.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ea: Foreword 1: An Introduction to Metabolomics and Systems Biology 2: Metabolomics in Neuroscience and Neurology 3: Cardiovascular Disease and Health 4: Chronic Obstructive Pulmonary Disease (COPD) and Metabolomics 5: In Search of New Biomarkers for Liver Diseases 6: Influences Shaping Digestive Health Explored Using Metabolomics 7: Applications of Metabolomics in the Study of Pathogenic Microorganisms and Their Effects on Human Health 8: Type 2 Diabetes Mellitus and The Metabolic Syndrome 9: Biomarkers of Skeletal Muscle Regulation, Metabolism and Dysfunction 10: Applications of Metabolomics in Cancer Research","brand":"CABI Publishing","offers":[{"title":"Default Title","offer_id":49412327801175,"sku":"9781786395429","price":46.98,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781786395429.jpg?v=1730516399"},{"product_id":"peptides-in-energy-balance-and-obesity-9781845934071","title":"Peptides in Energy Balance and Obesity","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eObesity is one of the most relevant public health concerns today and it is now evident that body weight control is achieved through highly integrated physiological interactions like nutrient selection as well as being influenced by genetic and environmental factors. Moreover, energy balance regulation is a complex process aimed at maintaining constant energy stores. Presenting a detailed and comprehensive account of the roles of specific peptides in energy balance, food intake control and co-morbidities, this review provides a better understanding of the patho-physiology of energy balance and obesity.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSection 1: Central pathways involved in the control of food intake and energy expenditure 1: Orexigenic neuropeptides: Hypothalamic regulation of appetite 2: Anorexigenic peptides 3: Newcomers and supporting actors Section 2: Peripheral signals participating in energy homeostasis and obesity: associated alterations 4: The gut as a second brain 5: The adipo-hepato-insular axis in glucose homeostasis 6: Elements of the adipostat 7: Adipocytokines participating in the immune-stress response 8: Peptides involved in vascular homeostasis 9: Natriuretic peptides and other lipolytic peptides involved in the control of lipid mobilization Section 3: Integrative Perspectives 10: Hierarchy of neural pathways controlling energy homeostasis 11: Relevance of reward signals in the homeostatic control of energy balance 12: Overview of the Integrative physiology of adipose tissue in energy homeostasis 13: Is the energy homeostasis system inherently biased toward weight gain? A teleological molecular physiological and clinical view 14: Embracing complexity: The emergence of functional neuroimaging and other methodologies to study the role of the human brain in the pathophysiology of obesity. 15: Application of \"\"OMICS\"\" strategies to obesity research 16: Implications for the future of obesity management\"","brand":"CABI Publishing","offers":[{"title":"Default Title","offer_id":49413564596567,"sku":"9781845934071","price":103.82,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781845934071.jpg?v=1730520623"},{"product_id":"amino-acids-in-human-nutrition-and-health-9781845937980","title":"Amino Acids in Human Nutrition and Health","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eHuman health issues relating to amino acids are extremely broad and include metabolic disorders of amino acid metabolism as well as their presence in food and use as supplements. This book covers the biochemistry of amino acid metabolism in the context of health and disease. It discusses their use as food supplements, in clinical therapy and nutritional support and focuses on major recent developments, highlighting new areas of research that will be needed to sustain further interest in the field.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePART I: ENZYMES AND METABOLISM 1: Glutamate Dehydrogenase 2: Aminotransferases 3: Arginase 4: Bypassing the Endothelial L-Arginine-Nitric-Oxide Pathway: Effects of Dietary Nitrite and Nitrate on Cardiovascular Function 5: Histidine Decarboxylase 6: Glutamate Decarboxylase 7: Glutaminase 8: D-Serine and Serine Racemase in Retina 9: Tryptophan Hydroxylase 10: Methionine Metabolism PART II: DYNAMICS 11: Amino Acid Transport Across Each Side of the Blood-Brain Barrier 12: Inter-Organ Fluxes of Amino Acids 13: Cellular Adaptation to Amino Acid Availability: Mechanisms Involved in the Regulation of Gene Expression PART III: NUTRITION 14: Endogenous Amino Acids at the Terminal Ileum of the Adult Human 15: Metabolic Availability of Amino Acids in Food Proteins: New Methodology 16: Amino Acid Requirements: Quantitative Estimates 17: Amino Acid Supplements and Muscular Performance 18: Amino Acids in Clinical and Nutritional Support: Glutamine in Duchenne Muscular Dystrophy 19: Adverse Effects 20: The Umami Taste of Glutamate PART IV: HEALTH 21: Homocysteine Status: Factors Affecting and Health Risks 22: Modified Amino Acid-Based Molecules: Accumulation and Health Implications 23: Phenylketonuria: Newborn Identification Through to Adulthood 24: Principles of Rapid Tryptophan Depletion and its use in Research on Neuropsychiatric Disorders 25: Excitatory Amino Acids in Neurological and Neurodegenerative Disorders 26: Efficacy of L-DOPA Therapy in Parkinson's Disease 27: Amino Acid Profiles for Diagnostic Applications PART V: CONCLUSIONS 28: Emergence of a New Momentum","brand":"CABI Publishing","offers":[{"title":"Default Title","offer_id":49413569937751,"sku":"9781845937980","price":141.48,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781845937980.jpg?v=1730520640"},{"product_id":"diabetes-stoffwechsel-und-hormonelle-storungen-9783110681925","title":"Diabetes, Stoffwechsel und hormonelle Störungen","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"De Gruyter","offers":[{"title":"Default Title","offer_id":49416188035415,"sku":"9783110681925","price":65.25,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783110681925.jpg?v=1730529208"},{"product_id":"pflegewissen-diabetes-praxistipps-fur-die-betreuung-alterer-diabetes-patienten-9783642384080","title":"Pflegewissen Diabetes: Praxistipps für die","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eIn ambulanten und stationären Pflegeieinrichtungen ist mehr als jeder 4. Bewohner Diabetiker. Viele von ihnen sind insulinbehandelt. Die Tendenz ist steigend. Das Pflegepersonal übernimmt hier einen wichtigen Part in der Betreuung und Therapiebegleitung geriatrischer Patienten mit Diabetes. Die Schulung der Pflegekräfte während der Ausbildung ist unzureichend und viele Aspekte der modernen Diabetologie sind den Pflegenden nicht bekannt.\u003c\/p\u003e\u003cp\u003eDieses Handbuch für die Praxis und die Fortbildung enthält alle wichtigen Zusatzinformationen, die Pflegende benötigen: Symptome und Krankheitsbild Diabetes mellitus Typ 2 bei geriatrischen Patienten, Begleit- und Folgeerkrankungen wie z.B. Diabetes bei Demenz, Therapiemöglichkeiten,  Pflegemaßnahmen, Patientenempowerment, Qualitätsmanagement und Schulung der Mitarbeiter.  \u003c\/p\u003e\u003cp\u003eEin Handbuch für die Pflegepraxis, Fortbildung und alle Mitarbeiter, die ältere Menschen mit Diabetes mellitus betreuen und unterstützen. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e“... Diabetes-Pflegekräfte und alle Pflegenden, die sich mit dem komplexen Thema vertraut machen möchten, finden hier fundiertes, aktuelles Hinhtergrundwissen und Anregungen für den praktischen Pflegealltag. Das Lehrbuch eignet sich als Begleitmaterial zu allen Fort- und Weiterbildungen mit dem Thema Diabetes in der Pflege, zum Nachschlagen und zum Auffrischen bereits vorhandener Kenntnisse.” (in: Häusliche Pflege, Heft 7, Juli 2016)\u003c\/p\u003e\u003cbr\u003e   “...   Jedes Kapitel schließt mit einer LIteraturangabe. Dass es sich um ein   Praxisbuch handelt, wird durch viele Patientenbeispiele mit ausführlichen   Erklärungen und Lösungsmöglichkeiten deutlich. ... Ein Buch für alle an der   Pflege von Diabetikern Beteiligten und diejenigen, die zum Thema viel wissen   wollen.” (Sissi Kuhn-Prinz, in: Insuliner, Jg. 33, 15. Juni 2015)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eDiabetes mellitus im hohen Alter: Definition, Symptome, Assessment.- Begleit- und Folgeerscheinungen: Hypertonie, Herzinsuffizienz, Diabetisches Fußsyndrom, Diabetisches Handsyndrom, Diabetisches Retinopathie, Diabetische Nephropathie, Hautkrankheiten.- Therapie: Bewegung, Ernährung, OAD, Insulintherapie, Inkretine, Herausforderungen bei der Therapie.- Pflege des älteren Patienten.- Förderung des pflegebedürftigen Diabetes-Patienten, Pflegeassessment, Pflegeberatung, Anleitung zum DSM.- Diabetes-Behandlungspflege: Injektionen, Stoffwechselkontrolle, Wundmanagement, Akutkomplikationen.- Besondere Pflegeaspekte: Mundhygiene, Fußpflege, Kleidung, Schuhe, Mobilisierung, Ernährung.- Spezielle Situationen: Kognitive Störungen, Depressionen, Infektionen, Schluckstörungen, Intensivmedizinische Eingriffe, Palliative Pflege, Patienten mit Migrationshintergrund.- Diabetes-Pflege-Qualitätsmanagement.- Schulung von Personal in der Diabetes-Pflege.- Aufbau Diabetes-Versorgungsnetzwerkes.- Anhang.\u003c\/p\u003e","brand":"Springer-Verlag Berlin and Heidelberg GmbH \u0026 Co. KG","offers":[{"title":"Default Title","offer_id":49420036768087,"sku":"9783642384080","price":37.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783642384080.jpg?v=1730540557"}],"url":"https:\/\/bookcurl.com\/collections\/metabolism.oembed?page=5","provider":"Book Curl","version":"1.0","type":"link"}