{"title":"Biochemistry Books","description":"","products":[{"product_id":"the-immortal-life-of-henrietta-lacks-9781035038619","title":"The Immortal Life of Henrietta Lacks","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eRebeca Skloot is the author of \u003ci\u003eThe Immortal Life of Henrietta Lacks\u003c\/i\u003e and an award-winning science writer whose articles have appeared in the \u003ci\u003eNew York Times Magazine \u003c\/i\u003eand \u003ci\u003eO, the Oprah Magazine\u003c\/i\u003e, among others. She has worked as a correspondent for NPR's \u003ci\u003eRadioLab\u003c\/i\u003e and PBS's \u003ci\u003eNova ScienceNOW\u003c\/i\u003e, and blogs about science, life, and writing at Culture Dish, hosted by \u003ci\u003eSeed\u003c\/i\u003e magazine. She also teaches creative nonfiction at the University of Memphis.","brand":"Pan Macmillan","offers":[{"title":"Default Title","offer_id":48087925031255,"sku":"9781035038619","price":10.44,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781035038619.jpg?v=1713543480"},{"product_id":"biochemistry-9780190847685","title":"Biochemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eBiochemistry: The Molecular Basis of Life is an intermediate, one-semester text written for students on degree pathways in Chemistry, Biology, and other Health and Life Sciences. Designed for students who need a solid introduction to biochemistry, but are not specializing in the subject, the text focuses on essential biochemical principles that underpin the modern life sciences, and offers the most balanced coverage of chemistry and biology of any text on the market. The text equips students with a complete view of the living state, emphasizes problem solving, and applies biochemical principles to the fields of Health, Agriculture, Engineering, and Forensics, to show students the relevance of their learning. McKee and McKee is respected for its balance of biology and chemistry, consistently placing biochemical principles into the context of the physiology of the cell and biomedical applications.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eMcKee's Biochemistry is by far the best available textbook on the market for a one semester undergraduate Biochemistry course. It is very reader-friendly and has a better flow than most Biochemistry textbooks. This textbook goes beyond being a good reference book for students. Several features like key concepts, medical correlations, chapter summaries, 'Biochemistry in Perspective,' and end-of-chapter problems help guide learning and provide valuable study materials. * Niina Ronkainen, Benedictine University     *\u003cbr\u003eMcKee's Biochemistry is an excellent, one-semester biochemistry text that covers the major topics to an appropriate depth for health professions students. It is concise yet provides enough details to lay a solid biochemistry foundation. * Joe Deweese, Lipscomb University   *\u003cbr\u003eThe amount of material covered and the depth of the coverage is very good for a one-semester biochemistry course. The clinical examples to start each chapter are very nice and a good way to interest students in the material. The writing is at a level that will be helpful to students. * Michael Gunther, West Virginia University     *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eChapter Opening Vignettes  Biochemistry in Perspective Essays  Biochemistry in the Lab Boxes  Preface  General and Organic Chemistry Review Primer   1. Biochemistry: An Introduction  2. Living Cells  3. Water: The Matrix of Life  4. Energy  5. Amino Acids, Peptides, and Proteins  6. Enzymes  7. Carbohydrates  8. Carbohydrate Metabolism  9. Aerobic Metabolism I: The Citric Acid Cycle  10. Aerobic Metabolism II: Electron Transport and Oxidative Phosphorylation  11. Lipids and Membranes  12. Lipid Metabolism  13. Photosynthesis  14. Nitrogen Metabolism I: Synthesis  15. Nitrogen Metabolism II: Degradation  16. Integration of Metabolism  17. Nucleic Acids  18. Genetic Information  19. Protein Synthesis   Appendix: Solutions  Credits","brand":"Oxford University Press Inc","offers":[{"title":"Default Title","offer_id":48732543975767,"sku":"9780190847685","price":136.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780190847685.jpg?v=1719997359"},{"product_id":"the-science-and-craft-of-artisanal-food-9780190936587","title":"The Science and Craft of Artisanal Food","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eYou are what you eat, and today's consumers care about the origins of their food. Artisanal food embodies those concerns, tailoring processes to raw materials to achieve the artisan's vision of the perfect product. The Science and Craft of Artisanal Food describes the science behind small and large-scale production of food, distinguishing artisanal production from normal commercial practice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Marketing Artisanal Products 2. Beer: Artfully Scientific on Every Level 3. Artist Winemaker 4. Artisanal Chocolate 5. Artisanal Coffee 6. Artisanal Cheese 7. The Chemistry and Flavor of Artisanal Honey 8. Industrial and Artisanal Olive Oil 9. Artisanal Fruits and Vegetables","brand":"Oxford University Press Inc","offers":[{"title":"Default Title","offer_id":48732550627671,"sku":"9780190936587","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"introduction-to-protein-science-architecture-function-and-genomics-9780198716846","title":"Introduction to Protein Science Architecture","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten by a leading author in the field, Introduction to Protein Science provides a wide-ranging perspective on the study of protein structure and function in the context of bioinformatics and genomics. Opportunities for active learning are provided both in the text and online, enabling students to develop their problem solving skills.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eThe third edition of Introduction to Protein Science continues to be a brilliant superior textbook for undergraduate and new postgraduate students in biology and chemistry. * Acta Crystallographica Section D, Volume D72, Part 12 (pp. 1227-1309, 1 December 2016) *\u003cbr\u003eIt would be difficult to express the qualities of this book better than Doolittle (2005) in his review of the first edition: How can a book with only seven chapters cover so many topics so thoroughly and so well? For one thing, Lesk is a gifted writer with a knack for making complex material eminently understandable. For another, he has managed an adroit balancing of the carefully crafted main text with dozens of well-situated \"boxes\" and \"case studies\", each of which provides intriguing connections to the subject at hand. * Acta Crystallographica Section D, Volume D72, Part 12 (pp. 1227-1309, 1 December 2016) *\u003cbr\u003eThis new edition is, above all, an excellent update of the previous one. * Acta Crystallographica Section D, Volume D72, Part 12 (pp. 1227-1309, 1 December 2016) *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Introduction ; 2. Protein structure ; 3. Protein structure determination ; 4. Bioinformatics of protein sequence and structure ; 5. Proteins as catalysts: enzyme structure, kinetics, and mechanism ; 6. Proteins with partners ; 7. Evolution of protein structure and function ; 8. Protein folding and design ; 9. Proteomics and systems biology","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732769059159,"sku":"9780198716846","price":55.09,"currency_code":"GBP","in_stock":true}]},{"product_id":"organic-chemistry-9780198759775","title":"Organic Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOrganic chemistry is the chemistry of compounds of carbon. The ability of carbon to link together to form long chain molecules and ring compounds as well as bonding with many other elements has led to a vast array of organic compounds. These compounds are central to life, forming the basis for organic molecules such as nucleic acids, proteins, carbohydrates, and lipids. In this Very Short Introduction Graham Patrick covers the whole range of organic compounds and their roles. Beginning with the structures and properties of the basic groups of organic compounds, he goes on to consider organic compounds in the areas of pharmaceuticals, polymers, food and drink, petrochemicals, and nanotechnology. He looks at how new materials, in particular the single layer form of carbon called graphene, are opening up exciting new possibilities for applications, and discusses the particular challenges of working with carbon compounds, many of which are colourless. Patrick also discusses techniques used in the field.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eREFERENCES; FURTHER READING; INDEX","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732779413847,"sku":"9780198759775","price":9.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198759775.jpg?v=1719998365"},{"product_id":"what-is-life-how-chemistry-becomes-biology-oxford-landmark-science-9780198784791","title":"What is Life How Chemistry Becomes Biology Oxford","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eSeventy years ago, Erwin Schrödinger posed a profound question: ''What is life, and how did it emerge from non-life?'' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of ''systems chemistry'' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications.Oxford Landmark Science books are ''must-read'' classics of modern science writing which have crystallized big ideas, and shaped the way we think.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eIn this inspiring book, Pross provides an engaging account of the view that systems chemistry can bridge the hitherto unassailable abiogenic\/biogenic divide. In a carefully constructed, almost forensic, analysis, he confronts crucial issues, such as the conceptual gulf between the biochemist's chicken and egg problem...and the fundamental role of dynamic kinetic stability in the process of life. * Ben Mepham, The Biologist *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePrologue 1: Living things are so very strange 2: Historic quest for a theory of life 3: Understanding 'understanding' 4: Stability and instability 5: The knotty origin of life problem 6: Biology's crisis of identity 7: Biology is chemistry 8: What is Life? References and Notes Index","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732782821719,"sku":"9780198784791","price":999.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198784791.jpg?v=1719998377"},{"product_id":"oxford-handbook-of-medical-sciences-9780198789895","title":"Oxford Handbook of Medical Sciences","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten by biomedical scientists and clinicians to disseminate the fundamental scientific principles that underpin clinical medicine, this new edition provides a clear, easily digestible account of basic cell physiology and biochemistry, and an investigation of the traditional piers of medicine.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition I have no doubt that OHMS is one of the best books I have ever bought. * Medical Student, University of Edinburgh *\u003cbr\u003eI would certainly recommend this book for clinical students who want to refresh some basic sciences later in their education. This is a reliable reference book which I think will serve me very well into my clinical years and I shall keep by my desk for those moments where I need to find a long-ago learnt and now-forgotten fact! * Cambridge Medicine Journal *\u003cbr\u003eThis book represents excellent value for money and is a superb offering which is now in a mature third edition. * Dr Harry Brown, Pavilion Health Today *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Cellular structure and function 2: Cellular metabolism 3: Molecular and medical genetics 4: Nerve and muscle 5: Musculoskeletal system 6: Respiratory and cardiovascular systems 7: Urinary system 8: Digestive system 9: Endocrine organs 10: Reproduction and development 11: Neuroanatomy and neurophysiology 12: Infection and immunity 13: Growth of tissues and organs 14: Medicine and society 15: Techniques of medical sciences","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732784722263,"sku":"9780198789895","price":32.29,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198789895.jpg?v=1719998386"},{"product_id":"chemistry-for-the-biosciences-9780198791041","title":"Chemistry for the Biosciences","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eChemistry enables our eyes to detect the world around us; it determines whether something tastes sweet or sour; it helps genetic information pass accurately from one generation to the next. Ultimately, chemistry powers life itself. We don''t need to dig very deep to answer the question: why do biologists need chemistry? Building on the success of the first three editions, Chemistry for the Biosciences introduces students to all the chemistry they need to understand the biological world. Renowned for its clear and straightforward explanations, the book uses everyday examples and analogies throughout to help students get to grips with chemical concepts, and presents them in context of biological systems wherever possible so they can see how chemistry relates to their wider studies. With topics drawn from organic, physical, and inorganic chemistry, students will encounter a broad range of essential concepts. Chemistry for the Biosciences includes many learning features - both in print and\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Introduction: why biologists need chemistry 2: Atoms: the foundations of life 3: Compounds and chemical bonding: bringing atoms together 4: Molecular interactions: holding it all together 5: Moles, concentrations, and dilutions: making sense of chemical numbers 6: Hydrocarbons: the framework of life 7: Functional groups: adding function to the framework of life 8: Molecular shape and structure: life in three dimensions 9: Isomerism: generating chemical variety 10: Biological macromolecules: the infrastructure of life 11: Metals in biology: life beyond carbon 12: Chemical reactions, oxidation, and reduction: bringing molecules to life 13: Reaction mechanisms: the chemical changes that drive the chemistry of life 14: Energy: what makes reactions go? 15: Equilibria: how far do reactions go? 16: Kinetics: what affects the speed of a reaction? 17: Acids, bases, and buffer solutions: life in an aqueous environment 18: Chemical analysis: characterizing chemical compounds","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732784886103,"sku":"9780198791041","price":48.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198791041.jpg?v=1719998387"},{"product_id":"physical-chemistry-for-the-life-sciences-9780198830108","title":"Physical Chemistry for the Life Sciences","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eA balanced presentation of the concepts of physical chemistry, and their applications to biology and biochemistry. Written to straddle the worlds of physical chemistry and the life sciences, it shows how the tools of physical chemistry can elucidate biological questions.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eFocus 1: Biochemical Thermodynamics: The First Law Focus 2: Biochemical Thermodynamics: The Second Law Focus 3: Water and Aqueous solutions Focus 4: Chemical equilibrium Focus 5: Ion and Electron Transport Focus 6: The Rates of Reactions Focus 7: Biochemical kinetics Focus 8: Atoms Focus 9: Molecules Focus 10: Macromolecules and self-assembly Focus 11: Biochemical spectroscopy Focus 12: Scattering techniques Focus 13: Gravimetric methods","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732800942423,"sku":"9780198830108","price":137.74,"currency_code":"GBP","in_stock":true}]},{"product_id":"protein-science-9780198846451","title":"Protein Science","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten primarily for students embarking on an undergraduate bioscience degree, this primer introduces students to the essential topics in protein science clearly and concisely by describing the basic chemical structure of proteins, the factors that stabilize protein structures, protein function, and protein evolution. It begins by placing proteins in their general context in life. They are synthesized as amino-acid sequences encoded in genomes, and fold spontaneously to three-dimensional structures. This is the point where life makes the tremendous leap from the one-dimensional world of genome and amino-acid sequences, to the three-dimensional world of protein structures - indeed, the world which we inhabit.  Protein Science prepares readers for later more advanced study of the subject, but will also leave readers who do not go on to such advanced study with a satisfying grasp of the essentials of the subject.Protein Science is supported by online resources and is available for studen\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Introduction 2: Protein structure 3: Purification and structure determination of proteins 4: Survey of protein functions 5: Protein evolution","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732809986391,"sku":"9780198846451","price":23.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198846451.jpg?v=1719998493"},{"product_id":"biochemistry-9780198848394","title":"Biochemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten primarily for 16-19 year old students, this primer aims to extend students'' knowledge and inspire them to take their school-level learning further. It explores topics that are familiar from the curriculum and also introduces new ideas, giving students a first taste of the study of biology beyond school-level and demonstrating how concepts frequently encountered at school are relevant to and applied in current research. This is the ideal text to support students who are considering making the transition from studying biology at school to university.  This is a concise, stimulating introduction to the fundamental biomolecules in cells and organisms, and the exciting ways biochemistry could be used to solve global problems, both now and in the future.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Carbohydrates: Why life is sweet 2: Lipids and Proteins: the building blocks of a cell 3: Nucleotides and Nucleic Acids: Biology's information stores 4: Metabolism: Transforming energy and biomolecules 5: Maintaining a Metabolic Balance 6: Solving Tomorrow's Problems with Natural Products 7: Solving Tomorrow's Problems: Bioenergy and the environment","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732811329879,"sku":"9780198848394","price":29.6,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198848394.jpg?v=1719998501"},{"product_id":"a-primer-on-stable-isotopes-in-ecology-9780198854494","title":"A Primer on Stable Isotopes in Ecology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIn the past few decades, the field of ecology has made huge advancements thanks to stable isotopes. Ecologists need to understand the principles of stable isotopes to fully appreciate many studies in their discipline. Ecologists also need to be aware of isotopic approaches to enrich their toolbox for further advancing the discipline. A Primer on Stable Isotopes in Ecology is a concise and foundational resource for anyone interested in acquiring theoretical and practical knowledge for the application of stable isotopes in ecology.Readers will gain a more in-depth and complete knowledge of stable isotopes and explore isotopic methods used in ecological research, learning about stable isotope definitions, measurement, ecological processes, and applications in research. Chapters include in-depth descriptions of stable isotopes and their notation, isotope fractionation, isotope mixing, heavy isotope enrichment, and quantification methods by mass spectrometry and laser spectroscopy. The text\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1: Stable isotopes as a tool for ecologists 2: Stable isotopes, notations, and standards 3: Isotopic fractionation 4: Isotope mixing 5: Heavy isotope enrichments 6: Measuring stable isotopes","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732814934359,"sku":"9780198854494","price":39.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198854494.jpg?v=1719998514"},{"product_id":"mann-j-essentials-of-human-nutrition-6e-9780198866671","title":"Mann J Essentials of Human Nutrition 6e","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eEssentials of Human Nutrition provides a complete and student-friendly introduction to the field for those embarking on courses in nutrition, or related subjects, for the first time. Written by an international team of experts, every chapter is carefully edited to give consistently clear and coherent explanations of all of the essential principles of nutrition. Key Features BL Chapters cover a broad range of disciplines to help students develop a complete understanding of the subject.BL Inter-chapter links help students see connections between different topics and build up a coherent picture of the subject as a whole.BL The text explains the impact of nutritional principles applied in practice, for example, in the context of sports and health care.New to this EditionThis sixth edition has been updated to incorporate new research and emerging topics such as biomarkers, assessment of nutritional status, and binge-eating disorders. Digital Formats and ResourcesEssentials of Human Nutrition is available for students and institutions to purchase in a variety of formats, and is supported by online resources.BL The e-book offers a mobile experience and convenient access: www.oxfordtextbooks.co.uk\/ebooksBL Lecturer resources BL Image bank\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition A great introduction to basic nutrition, diet, factors influencing dietary choice, dietary needs through the life course, and a taster of how diet and poor nutrition can be both a cause and a consequence of disease.\u003cbr\u003eAn essential textbook for any introductory course in nutrition.\u003cbr\u003eA comprehensive, well written, and relevant textbook which provides an excellent overview of the current field of human nutrition.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart 1: Introducing Human Nutrition 1: A. Stewart Truswell, Jim Mann, and Leanne Hodson: Introduction Part 2: Energy and Macronutrients 2: Jim Mann and Andrew Reynolds: Carbohydrates 3: C. Murray Skeaff, Jim Mann, and Leanne Hodson: Lipids 4: Colleen S. Deane, Daniel J. Wilkinson, and Philip J. Atherton: Protein 5: Andrew M. Prentice: Energy 6: A. Stewart Truswell: Alcohol Part 3: Organic and Inorganic Essential Nutrients 7: Lewis J. James and Gethin H. Evans: Water, Electrolytes, and Acid-base Balance 8: Helen Lambert, Ohood Hakim, and Susan A. Lanham-New: Major Minerals: Calcium and Magnesium 9: Patrick MacPhail: Iron 10: Samir Samman, Sheila Skeaff, Christine D. Thomson, and A. Stewart Truswell: Trace Elements 11: David I. Thurnham: Vitamin A and Carotenoids 12: A. Stewart Truswell: The B Vitamins 13: A. Stewart Truswell and Jim Mann: Vitamins C and E 14: A. Stewart Truswell: Vitamins D and K 15: Bernhard Watzl: Other Biologically Active Substances in Plant Foods: Phytochemicals 16: Anne-Marie Minihane: Nutrition, Genetics, and Personalized Nutrition Part 4: Nutrition-Related Disorders 17: Mike Lean: Overweight and Obesity 18: A. Stewart Truswell: Protein-Energy Malnutrition 19: Jim Mann and Rachael McLean: Cardiovascular Diseases 20: Kathryn E. Bradbury and Timothy J. Key: Nutrition and Cancer 21: Jim Mann: Diabetes Mellitus and the Metabolic Syndrome 22: Hannah Turner and Robert Peveler: The Eating Disorders: Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, and OSFED Part 5: Foods 23: Andrew Reynolds, A. Stewart Truswell, Margaret Allman-Farinelli, Meika Foster, Anna Rangan, Leanne Hodson, and Kim Bell-Anderson: Food Groups 24: Martijn B. Katan: Functional Foods and Health Claims 25: Peter Williams and Paul Brent: Food Toxicity and Safety Part 6: Changing Food Habits 26: A. Stewart Truswell and Helen Leach: Food Habits 27: A. Stewart Truswell, Leanne Hodson, and Jim Mann: Nutritional Recommendations for the General Population 28: Susan A. Jebb: Public Health Approaches to Implement Dietary Recommendations 29: C. Murray Skeaff: Dietary Patterns 30: Wilma Waterlander and Boyd Swinburn: Food Systems: Challenges and Ways Forward 31: Tim Lang and Pamela Mason: Nutrition, the Environment, and Sustainable Diets Part 7: Life Stages 32: Annie S. Anderson: Pre-Pregnancy, Pregnancy, and Lactation 33: Anne-Louise Heath, Helen Crawley, and Rachael Taylor: Infant Feeding and Eating Well for Toddlers 34: Rachael Taylor and Anne-Louise Heath: Childhood and Adolescent Nutrition 35: Sian Robinson and Clare Corish: Nutrition and Ageing Part 8: Nutritional Assessment 36: Philippa Lyons-Wall: Food Analysis, Food Composition Tables, and Databases 37: Jim Mann and Silke Morrison: Dietary Assessment 38: A. Stewart Truswell: Assessment of Nutritional Status 39: Nita G. Forouhi and Albert Koulman: Biomarkers Part 9: Applications 40: Louise M. Burke: Sports Nutrition 41: Claire Smith and Winsome R. Parnell: Nutritional Consequences of Poverty and Food Insecurity in Developed Countries 42: Suzie Ferrie: Food in Hospitals 43: Ross C. Smith: Nutritional Support for Hospital Patients","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732821520727,"sku":"9780198866671","price":67.62,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780198866671.jpg?v=1719998544"},{"product_id":"a-dictionary-of-biomedicine-9780199549351","title":"A Dictionary of Biomedicine","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis dictionary includes 10,000 A-Z entries on all areas of biomedicine. It also covers terms from related areas, including anatomy, genetics, pathology, pharmacology, and clinical medicine. Fully cross-referenced and with web links, this is a clear and authoritative guide to an increasingly important area of medicine.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePREFACE; A NOTE ON CONVENTIONS; LISTING OF NAVIGATIONAL ENTRIES; A DICTIONARY OF BIOMEDICINE; APPENDIX 1: THE GREEK ALPHABET; APPENDIX 2: SI UNITS; APPENDIX 3: SINGLE-LETTER CODES FOR AMINO ACIDS","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732856975703,"sku":"9780199549351","price":15.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199549351.jpg?v=1719998694"},{"product_id":"protein-structure-and-function-9780199556847","title":"Protein Structure and Function","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eHow does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein?Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. 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Structure Determination","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732864184663,"sku":"9780199556847","price":66.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199556847.jpg?v=1719998722"},{"product_id":"introduction-to-glycobiology-9780199569113","title":"Introduction to Glycobiology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIntroduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eReview from previous edition This book is an absolute must for all lecturers and students alike of glycobiology ... 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Kamerling, Utrecht University *\u003cbr\u003eDr Taylor and Professor Drickamer should be congratulated on writing a textbook that presents the enormous subject of glycobiology with energy and enthusiasm and doing so in a manner that should be accessible to their target audience. * Biochemist e-volution, April 2006 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePART 1: STRUCTURES AND BIOSYNTHESIS OF GLYCANS; PART 2: GLYCANS IN BIOLOGY","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732866445655,"sku":"9780199569113","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"infection-immunity-9780199609505","title":"Infection  Immunity","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eGives a perfectly balanced overview of the field, describing the key infectious agents our bodies encounter and how our immune system responds to them. 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Changing perspectives ; Further reading ; Index","brand":"Oxford University Press","offers":[{"title":"Default Title","offer_id":48732880798039,"sku":"9780199672875","price":9.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780199672875.jpg?v=1719998795"},{"product_id":"beer-9780199996742","title":"Beer","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eDespite competition from an ever-growing range of alternative adult beverages, beer remains a vastly important beverage globally. There is a huge diversity of beer styles, drinks suited not only to refreshment and delight in themselves, but also to suit any drinking occasion, including alongside food of all types. There is nutritional value in beer and evidence that, consumed responsibly, it can be a valuable part of a well-balanced diet. This relates to the wholesomeness of the basic materials employed for the brewing of beer, notably malt and hops, but also the nature of the longstanding processes that are employed in converting cereals such as barley and wheat into malt and thence through the time-honored stages of brewing. This book explains these issues- history, nature and complexity of the modern brewing business, types of beer, quality attributes of beer, the underpinning processes, and much more. 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This fully updated fourth edition provides practical guidance about preparation, key uses and pitfalls of antibodies for immunohistology in a unique A-Z format. Seventeen full colour infographics present detail about specific biomarkers, including FOXL2, GATA3 and SOX10, pulling out information about expression in tissues and prognosis. Expanded with new biomarkers and the removal of biomarkers that are no longer in common use, each entry in this concise new edition follows a standard structure for quick and easy access by busy readers.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart I. Antibodies; Part II. Appendices.","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":48738311766359,"sku":"9781108491570","price":118.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781108491570.jpg?v=1723811916"},{"product_id":"cellular-signal-transduction-in-toxicology-and-pharmacology-9781119060260","title":"Cellular Signal Transduction in Toxicology and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eCovering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets.\u003cbr\u003e\u003cbr\u003e \u003cul\u003e \u003cli\u003eCombines fundamentals \/ basics with experimental applications that can help those involved in preclinical drug studies and translational research\u003c\/li\u003e \u003cli\u003eIncludes detailed presentations of study methodology and data collection, analysis, and interpretation\u003c\/li\u003e \u003cli\u003eDiscusses tools like experimental design, sample handling, analytical measurement techniques\u003c\/li\u003e \u003c\/ul\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of Contributors xv\u003c\/p\u003e \u003cp\u003eAbout the Editors xvii\u003c\/p\u003e \u003cp\u003ePreface xix\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction to Cellular Signal Transduction: The Connection Between a Biological System and Its Surroundings 1\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJonathan W. 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Neubig, Alice Han, \u003c\/i\u003eand\u003ci\u003e Maren Prediger\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Starting Big, but Ending Small 3\u003c\/p\u003e \u003cp\u003e1.1.1 Key Features of Signal Transduction 3\u003c\/p\u003e \u003cp\u003e1.2 Responding to Our Environment: Sensory Perception Begins and Ends with Signal Transduction 4\u003c\/p\u003e \u003cp\u003e1.2.1 Taste (Gustation) 4\u003c\/p\u003e \u003cp\u003e1.2.2 Smell (Olfaction) 5\u003c\/p\u003e \u003cp\u003e1.2.3 Sight (Vision) 6\u003c\/p\u003e \u003cp\u003e1.2.4 Sound (Audition) 6\u003c\/p\u003e \u003cp\u003e1.2.5 Touch (Somatosensation) 8\u003c\/p\u003e \u003cp\u003e1.3 Primary Transport Systems Involved in Signal Transduction 8\u003c\/p\u003e \u003cp\u003e1.3.1 Ion Channels, Transporters, and Ion Pumps 9\u003c\/p\u003e \u003cp\u003e1.3.2 Receptors 10\u003c\/p\u003e \u003cp\u003e1.3.3 Endocytosis 10\u003c\/p\u003e \u003cp\u003e1.3.4 Exosomes 11\u003c\/p\u003e \u003cp\u003e1.4 Key Organelles Involved in Signal Transduction 12\u003c\/p\u003e \u003cp\u003e1.4.1 Mitochondria 12\u003c\/p\u003e \u003cp\u003e1.4.2 Endoplasmic Reticulum 14\u003c\/p\u003e \u003cp\u003e1.4.3 Nucleus 15\u003c\/p\u003e \u003cp\u003eReferences 16\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Mechanisms of Cellular Signal Transduction 21\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRichard R. Neubig, Jonathan W. Boyd, Julia A. Mouch, \u003c\/i\u003eand\u003ci\u003e Nicole Prince\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Posttranslational Modifications and Their Roles in Signal Transduction 22\u003c\/p\u003e \u003cp\u003e2.1.1 Phosphorylation 22\u003c\/p\u003e \u003cp\u003e2.1.2 Acylation 24\u003c\/p\u003e \u003cp\u003e2.1.3 Alkylation 25\u003c\/p\u003e \u003cp\u003e2.1.4 Glycosylation 26\u003c\/p\u003e \u003cp\u003e2.1.5 Other PTMs 27\u003c\/p\u003e \u003cp\u003e2.2 Receptors 27\u003c\/p\u003e \u003cp\u003e2.3 Receptor Signaling Mechanisms 29\u003c\/p\u003e \u003cp\u003e2.3.1 Basic Principles of Signal Transduction Mechanisms 29\u003c\/p\u003e \u003cp\u003e2.3.1.1 Selectivity and Recognition 31\u003c\/p\u003e \u003cp\u003e2.3.1.2 Flexible Modularity 31\u003c\/p\u003e \u003cp\u003e2.3.1.3 Molecular Switches 34\u003c\/p\u003e \u003cp\u003e2.3.1.4 GPCRs and Second Messengers 36\u003c\/p\u003e \u003cp\u003e2.3.1.5 Amplification 39\u003c\/p\u003e \u003cp\u003e2.3.1.6 Turn‐Off Mechanisms 40\u003c\/p\u003e \u003cp\u003e2.3.1.7 Localization 40\u003c\/p\u003e \u003cp\u003e2.3.1.8 Biased Signaling\/Functional Selectivity 41\u003c\/p\u003e \u003cp\u003e2.4 Receptor Tyrosine Kinases 42\u003c\/p\u003e \u003cp\u003e2.5 Steroid Receptors 43\u003c\/p\u003e \u003cp\u003e2.6 Reactive Oxygen Species (ROS) 43\u003c\/p\u003e \u003cp\u003e2.7 Summary 44\u003c\/p\u003e \u003cp\u003eReferences 44\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 From Cellular Mechanisms to Physiological Responses: Functional Signal Integration Across Multiple Biological Levels 49\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRobert H. Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 49\u003c\/p\u003e \u003cp\u003e3.2 Cellular Information Flow: Mechanisms of Cellular Signal Integration and Regulation 50\u003c\/p\u003e \u003cp\u003e3.2.1 The InsR‐aPKC‐NF‐κB Signaling Axis 51\u003c\/p\u003e \u003cp\u003e3.2.2 Modes of Regulation in InsR‐PKC‐NF‐κB Signaling Axis 54\u003c\/p\u003e \u003cp\u003e3.2.3 Transcriptional Regulation 54\u003c\/p\u003e \u003cp\u003e3.2.4 Regulating the Regulators: Phosphatase‐Mediated Regulation of Signaling Molecules 59\u003c\/p\u003e \u003cp\u003e3.3 Crosstalk and Functional Signal Integration in Response to Insulin in Hepatocytes 60\u003c\/p\u003e \u003cp\u003e3.4 Systemic Signal Integration 65\u003c\/p\u003e \u003cp\u003e3.4.1 Pancreatic β‐Cells 65\u003c\/p\u003e \u003cp\u003e3.4.2 Skeletal Muscles 66\u003c\/p\u003e \u003cp\u003e3.4.3 Adipose Tissue 67\u003c\/p\u003e \u003cp\u003e3.5 Dysregulation of Insulin Signaling in the Etiology of Type 2\u003c\/p\u003e \u003cp\u003eDiabetes 67\u003c\/p\u003e \u003cp\u003eReferences 69\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Signal Transduction in Disease: Relating Cell Signaling to Morbidity and Mortality 73\u003cbr\u003e\u003c\/b\u003e\u003ci\u003ePatricia E. Ganey and Sean A. Misek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 73\u003c\/p\u003e \u003cp\u003e4.2 Fibrosis as an Example of Complex Signaling 75\u003c\/p\u003e \u003cp\u003e4.2.1 Development of Liver Fibrosis 75\u003c\/p\u003e \u003cp\u003e4.2.2 Animal Models of Hepatic Fibrosis 76\u003c\/p\u003e \u003cp\u003e4.2.3 Activation of Hepatic Stellate Cells 77\u003c\/p\u003e \u003cp\u003e4.2.4 Epithelial‐to‐Mesenchymal Transition (EMT) 78\u003c\/p\u003e \u003cp\u003e4.2.5 Other Cellular Interactions in Fibrosis 78\u003c\/p\u003e \u003cp\u003e4.2.6 Intracellular Signaling Pathways Critical to Liver Fibrosis 80\u003c\/p\u003e \u003cp\u003e4.2.6.1 TGF‐β1 80\u003c\/p\u003e \u003cp\u003e4.2.6.2 Kinase Pathways Involved in Fibrotic Responses 82\u003c\/p\u003e \u003cp\u003e4.2.6.3 HIF‐1α 83\u003c\/p\u003e \u003cp\u003e4.2.6.4 miRNA 84\u003c\/p\u003e \u003cp\u003e4.2.6.5 Toll‐Like Receptors (TLRs) 84\u003c\/p\u003e \u003cp\u003e4.3 Cancer Drug Resistance: Complex Cellular and Population Changes 85\u003c\/p\u003e \u003cp\u003e4.3.1 Genomic Resistance Mechanisms 85\u003c\/p\u003e \u003cp\u003e4.3.2 Non‐genomic Mechanisms 88\u003c\/p\u003e \u003cp\u003e4.3.3 Non‐cancer Drug Resistance Paradigms 88\u003c\/p\u003e \u003cp\u003e4.3.4 Tumor Heterogeneity as a Driver of Drug Resistance 89\u003c\/p\u003e \u003cp\u003e4.3.5 Mutational Drivers of Drug Resistance 90\u003c\/p\u003e \u003cp\u003e4.3.6 Drug‐Induced Rewiring of Signaling Networks as a Mechanism of Drug Resistance 91\u003c\/p\u003e \u003cp\u003e4.3.7 Parallel Pathways and Combination Treatments 93\u003c\/p\u003e \u003cp\u003e4.3.8 Epigenetic Mechanisms of Drug Resistance 95\u003c\/p\u003e \u003cp\u003e4.3.9 Summary of Cancer Drug Resistance 97\u003c\/p\u003e \u003cp\u003e4.4 Summary 98\u003c\/p\u003e \u003cp\u003eReferences 98\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Experimental Design in Signal Transduction 113\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eWeimin Gao, Meghan Cromie, Qian Wang, Zhongwei Liu, Song Tang, \u003c\/i\u003eand\u003ci\u003e Julie Vrana Miller\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Overview of Basic Experimental Design 113\u003c\/p\u003e \u003cp\u003e5.1.1 Independent Sample \u003ci\u003et\u003c\/i\u003e Test 114\u003c\/p\u003e \u003cp\u003e5.1.2 Completely Randomized Analysis of Variance (ANOVA) 114\u003c\/p\u003e \u003cp\u003e5.1.3 \u003ci\u003et\u003c\/i\u003e Test for Dependent Sample Design 115\u003c\/p\u003e \u003cp\u003e5.1.4 Randomized Block Design 115\u003c\/p\u003e \u003cp\u003e5.1.5 Completely Randomized Factorial Design 116\u003c\/p\u003e \u003cp\u003e5.1.6 Summary 116\u003c\/p\u003e \u003cp\u003e5.2 Aseptic Technique 116\u003c\/p\u003e \u003cp\u003e5.2.1 Sterile Work Environment and Laminar‐Flow Hood 117\u003c\/p\u003e \u003cp\u003e5.2.2 Good Personal Hygiene Practices 117\u003c\/p\u003e \u003cp\u003e5.2.3 Sterile Reagents and Materials 118\u003c\/p\u003e \u003cp\u003e5.2.4 Sterile Handling 118\u003c\/p\u003e \u003cp\u003e5.3 Biological Sample Collection, Processing, and Pretreatment Technology 119\u003c\/p\u003e \u003cp\u003e5.3.1 Sample Collection 119\u003c\/p\u003e \u003cp\u003e5.3.1.1 Sample Collection \u003ci\u003eIn Vivo\u003c\/i\u003e 119\u003c\/p\u003e \u003cp\u003e5.3.1.2 Cell Culture \u003ci\u003eIn Vitro\u003c\/i\u003e 120\u003c\/p\u003e \u003cp\u003e5.3.2 Sample Processing 121\u003c\/p\u003e \u003cp\u003e5.3.2.1 DNA Isolation 121\u003c\/p\u003e \u003cp\u003e5.3.2.2 RNA Extraction 121\u003c\/p\u003e \u003cp\u003e5.3.2.3 Protein Extraction 122\u003c\/p\u003e \u003cp\u003e5.4 Sample Storage 122\u003c\/p\u003e \u003cp\u003e5.5 Common \u003ci\u003eIn Vitro\u003c\/i\u003e Studies in Toxicology\/Pharmacology 123\u003c\/p\u003e \u003cp\u003e5.5.1 Cytotoxicity Studies 123\u003c\/p\u003e \u003cp\u003e5.5.2 Viability Assays 123\u003c\/p\u003e \u003cp\u003e5.5.2.1 Trypan Blue 123\u003c\/p\u003e \u003cp\u003e5.5.2.2 Erythrosin 124\u003c\/p\u003e \u003cp\u003e5.5.2.3 Crystal Violet Staining 124\u003c\/p\u003e \u003cp\u003e5.5.2.4 Neutral Red Staining 125\u003c\/p\u003e \u003cp\u003e5.5.3 Survival Assays 125\u003c\/p\u003e \u003cp\u003e5.5.3.1 Clonogenic or Colony Formation Assay 125\u003c\/p\u003e \u003cp\u003e5.5.3.2 Cell Cycle Analysis: Flow Cytometry 126\u003c\/p\u003e \u003cp\u003e5.5.4 DNA Damage Assays 126\u003c\/p\u003e \u003cp\u003e5.5.4.1 Comet Assay 127\u003c\/p\u003e \u003cp\u003e5.5.4.2 Sister Chromatid Exchange Assay 127\u003c\/p\u003e \u003cp\u003e5.5.5 Southern Blot and DNA Sequencing 127\u003c\/p\u003e \u003cp\u003e5.5.5.1 Southern Blot 127\u003c\/p\u003e \u003cp\u003e5.5.5.2 DNA Sequencing 128\u003c\/p\u003e \u003cp\u003e5.5.5.3 Transfection and Gene Silencing 128\u003c\/p\u003e \u003cp\u003e5.5.6 RNA Quantification and Identification 128\u003c\/p\u003e \u003cp\u003e5.5.6.1 Northern Blot 128\u003c\/p\u003e \u003cp\u003e5.5.6.2 Promoter Deletion Analysis 129\u003c\/p\u003e \u003cp\u003e5.5.6.3 RNase Protection Assay 129\u003c\/p\u003e \u003cp\u003e5.5.7 Gene Expression 129\u003c\/p\u003e \u003cp\u003e5.5.7.1 Quantitative Real‐Time Polymerase Chain Reaction (qRT‐PCR) 130\u003c\/p\u003e \u003cp\u003e5.5.7.2 Microarray 130\u003c\/p\u003e \u003cp\u003e5.5.8 Protein‐Related Assays 131\u003c\/p\u003e \u003cp\u003e5.5.8.1 Bradford Assay 131\u003c\/p\u003e \u003cp\u003e5.5.8.2 Enzyme-Linked Immunosorbent Assay (ELISA) 131\u003c\/p\u003e \u003cp\u003e5.5.8.3 Western Blot and 2D Gel Electrophoresis 131\u003c\/p\u003e \u003cp\u003e5.5.8.4 Immunolocalization 132\u003c\/p\u003e \u003cp\u003e5.5.8.5 Immunoprecipitation Assays 132\u003c\/p\u003e \u003cp\u003e5.5.8.6 Chromatin Immunoprecipitation (ChIP) 132\u003c\/p\u003e \u003cp\u003e5.5.9 Epigenetics 133\u003c\/p\u003e \u003cp\u003e5.5.9.1 Bisulfite Pyrosequencing 133\u003c\/p\u003e \u003cp\u003e5.5.9.2 ChIP‐on‐Chip 133\u003c\/p\u003e \u003cp\u003e5.5.9.3 Multiplex miRNA Profiling 134\u003c\/p\u003e \u003cp\u003e5.6 Common \u003ci\u003eIn Vivo\u003c\/i\u003e Studies in Toxicology 134\u003c\/p\u003e \u003cp\u003e5.6.1 Toxicological Endpoints 134\u003c\/p\u003e \u003cp\u003e5.6.1.1 Maximum Tolerated Dose (MTD) 134\u003c\/p\u003e \u003cp\u003e5.6.1.2 Acute, Subchronic, and Chronic Toxicity 135\u003c\/p\u003e \u003cp\u003e5.6.1.3 Reproductive and Developmental Toxicity 135\u003c\/p\u003e \u003cp\u003e5.6.1.4 Genotoxicity and Carcinogenicity Studies 136\u003c\/p\u003e \u003cp\u003e5.6.2 Routes of Exposure 136\u003c\/p\u003e \u003cp\u003e5.6.2.1 Oral, Dermal, and Inhalation 136\u003c\/p\u003e \u003cp\u003e5.6.2.2 Exposure via Injection 137\u003c\/p\u003e \u003cp\u003e5.6.3 Animal Models 137\u003c\/p\u003e \u003cp\u003e5.6.3.1 Rodent Studies 137\u003c\/p\u003e \u003cp\u003e5.6.3.2 Other Studies 138\u003c\/p\u003e \u003cp\u003e5.7 Basic Advantages and Disadvantages Associated with Sample Types 138\u003c\/p\u003e \u003cp\u003e5.8 Human Epidemiology Studies 138\u003c\/p\u003e \u003cp\u003e5.8.1 Nonexperimental Studies 139\u003c\/p\u003e \u003cp\u003e5.8.2 Experimental Studies 139\u003c\/p\u003e \u003cp\u003e5.8.3 Molecular Epidemiology 140\u003c\/p\u003e \u003cp\u003e5.9 Examples of Tox‐ and Pharm‐Based Experiments Relevant to Signal Transduction Endpoints 140\u003c\/p\u003e \u003cp\u003e5.9.1 Cytotoxicity 141\u003c\/p\u003e \u003cp\u003e5.9.1.1 Nicotine‐Derived Nitrosamine Ketone (NNK) 141\u003c\/p\u003e \u003cp\u003e5.9.1.2 Doxorubicin (DOX) 142\u003c\/p\u003e \u003cp\u003e5.9.1.3 Curcumin 142\u003c\/p\u003e \u003cp\u003e5.9.1.4 Combination Effects of Cisplatin and\/or Leptomycin B (LMB) 143\u003c\/p\u003e \u003cp\u003e5.9.2 DNA Damage 143\u003c\/p\u003e \u003cp\u003e5.9.3 Cell Cycle and Apoptosis 145\u003c\/p\u003e \u003cp\u003e5.9.4 ROS Induction in A549 Cells After LMB and Epigallocatechin Gallate (EGCG) Treatment 146\u003c\/p\u003e \u003cp\u003e5.9.5 Signaling Pathways 146\u003c\/p\u003e \u003cp\u003e5.9.5.1 Metabolizing Alterations After Chemical Exposure 146\u003c\/p\u003e \u003cp\u003e5.9.5.2 p53 Signaling Pathways 148\u003c\/p\u003e \u003cp\u003e5.9.6 Protein Kinase B (Akt\/PKB)\/Mechanistic Target of Rapamycin (mTOR) Pathway Analysis Using Multiblot 150\u003c\/p\u003e \u003cp\u003e5.9.7 Discovery of Unrecognized Pathways\/Molecules Using Proteomics 150\u003c\/p\u003e \u003cp\u003e5.10 Coupling Experimental Results Within the Larger Literature Framework to Generate Information 152\u003c\/p\u003e \u003cp\u003e5.10.1 Cell Proliferation–EGFR Pathway 152\u003c\/p\u003e \u003cp\u003e5.10.2 Cell Cycle 154\u003c\/p\u003e \u003cp\u003e5.10.3 Signal‐Mediated Cell Death 156\u003c\/p\u003e \u003cp\u003e5.10.4 Reactive Oxygen Species (ROS) 161\u003c\/p\u003e \u003cp\u003eReferences 162\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Techniques for Measuring Cellular Signal Transduction 171\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJulie Vrana Miller, Weimin Gao, Meghan Cromie, \u003c\/i\u003eand\u003ci\u003e Zhongwei Liu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 171\u003c\/p\u003e \u003cp\u003e6.2 High‐Throughput Versus High‐Content Data 172\u003c\/p\u003e \u003cp\u003e6.2.1 Ergodic and Nonergodic Systems 173\u003c\/p\u003e \u003cp\u003e6.3 Methods to Measure Signal Transduction Data 173\u003c\/p\u003e \u003cp\u003e6.3.1 Microscopy 173\u003c\/p\u003e \u003cp\u003e6.3.1.1 Widefield Epifluorescence Microscopy 173\u003c\/p\u003e \u003cp\u003e6.3.1.2 Confocal Microscopy 174\u003c\/p\u003e \u003cp\u003e6.3.1.3 Immunohistochemistry 175\u003c\/p\u003e \u003cp\u003e6.3.1.4 FRET 178\u003c\/p\u003e \u003cp\u003e6.3.2 Enzyme‐Linked Immunosorbent Assay (ELISA) 179\u003c\/p\u003e \u003cp\u003e6.3.2.1 Competitive ELISA 179\u003c\/p\u003e \u003cp\u003e6.3.2.2 Sandwich ELISA 180\u003c\/p\u003e \u003cp\u003e6.3.2.3 Direct Cellular ELISA 180\u003c\/p\u003e \u003cp\u003e6.3.2.4 Multiplex Suspension Array Assays 181\u003c\/p\u003e \u003cp\u003e6.3.2.5 Electrochemiluminescence (ECL) Array 182\u003c\/p\u003e \u003cp\u003e6.3.3 Gel Electrophoresis 183\u003c\/p\u003e \u003cp\u003e6.3.4 Western Blot 183\u003c\/p\u003e \u003cp\u003e6.3.5 Protein Nuclear Magnetic Resonance (NMR) 186\u003c\/p\u003e \u003cp\u003e6.4 Techniques to Generate Large Datasets for Signal Transduction Network Analysis 187\u003c\/p\u003e \u003cp\u003e6.4.1 ’‐omics Using Mass Spectrometry 187\u003c\/p\u003e \u003cp\u003e6.4.1.1 Separation Techniques 188\u003c\/p\u003e \u003cp\u003e6.4.1.2 Phosphoprotein Enrichment for Phosphoproteomics: IMAC, MOAC, and SMOAC 189\u003c\/p\u003e \u003cp\u003e6.4.1.3 Quantitation with Chemical Tags: iTRAQ and TMT 190\u003c\/p\u003e \u003cp\u003e6.4.2 RNA Sequencing (RNA‐Seq) 190\u003c\/p\u003e \u003cp\u003e6.5 Bioenergetics 191\u003c\/p\u003e \u003cp\u003e6.5.1 Oxygen Consumption 191\u003c\/p\u003e \u003cp\u003e6.5.2 Reactive Oxygen Species (ROS) Fluorescent Probes 192\u003c\/p\u003e \u003cp\u003e6.5.3 ATP Assays 193\u003c\/p\u003e \u003cp\u003e6.5.4 Nicotinamide Adenine Dinucleotide (NADH) Assay 193\u003c\/p\u003e \u003cp\u003e6.5.5 Mitochondrial Membrane Potential 194\u003c\/p\u003e \u003cp\u003e6.6 Relating Signaling to Cellular Outcome Using Relevant Assays 194\u003c\/p\u003e \u003cp\u003e6.6.1 MTT\/MTS\/WST Assays 194\u003c\/p\u003e \u003cp\u003e6.6.2 LDH Assay 195\u003c\/p\u003e \u003cp\u003e6.6.3 Resazurin Assay (Alamar Blue) 196\u003c\/p\u003e \u003cp\u003e6.6.4 Cell Death: Plasma Membrane Degradation Assay 196\u003c\/p\u003e \u003cp\u003e6.7 Summary 196\u003c\/p\u003e \u003cp\u003eReferences 197\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Computational Methods for Signal Transduction: A Network Approach 201\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGiovanni Scardoni, Gabriele Tosadori, John Morris, Sakshi Pratap, Carlo Laudanna, \u003c\/i\u003eand\u003ci\u003e Alice Han\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 201\u003c\/p\u003e \u003cp\u003e7.2 Network Construction 203\u003c\/p\u003e \u003cp\u003e7.2.1 Introduction to Network Construction 203\u003c\/p\u003e \u003cp\u003e7.2.2 Network Construction from a Probe 203\u003c\/p\u003e \u003cp\u003e7.2.3 Mapping Methodology 204\u003c\/p\u003e \u003cp\u003e7.2.4 Small Networks 208\u003c\/p\u003e \u003cp\u003e7.2.5 Large Networks 208\u003c\/p\u003e \u003cp\u003e7.3 Facing the Network Analysis 209\u003c\/p\u003e \u003cp\u003e7.3.1 Centralities Definition and Description 211\u003c\/p\u003e \u003cp\u003e7.3.2 Global Parameters 211\u003c\/p\u003e \u003cp\u003e7.3.2.1 Diameter (Δ\u003ci\u003eG\u003c\/i\u003e) 211\u003c\/p\u003e \u003cp\u003e7.3.2.2 Average Distance 212\u003c\/p\u003e \u003cp\u003e7.3.3 Local Parameters 213\u003c\/p\u003e \u003cp\u003e7.3.3.1 Degree 213\u003c\/p\u003e \u003cp\u003e7.3.3.2 Eccentricity 214\u003c\/p\u003e \u003cp\u003e7.3.3.3 Closeness 215\u003c\/p\u003e \u003cp\u003e7.3.3.4 Radiality 215\u003c\/p\u003e \u003cp\u003e7.3.3.5 Centroid Value 217\u003c\/p\u003e \u003cp\u003e7.3.3.6 Stress 219\u003c\/p\u003e \u003cp\u003e7.3.3.7 S.‐P. Betweenness 219\u003c\/p\u003e \u003cp\u003e7.3.3.8 Eigenvector 220\u003c\/p\u003e \u003cp\u003e7.3.3.9 Bridging Centrality 221\u003c\/p\u003e \u003cp\u003e7.3.3.10 Edge Betweenness 221\u003c\/p\u003e \u003cp\u003e7.3.3.11 Normalization and Relative Centralities 222\u003c\/p\u003e \u003cp\u003e7.3.4 Clusters 222\u003c\/p\u003e \u003cp\u003e7.4 Employing Centrality Analysis to Evaluate Stressed Biological Systems 224\u003c\/p\u003e \u003cp\u003e7.5 Interference Notion: How to Perform Virtual Knockout Experiments on Biological Networks 226\u003c\/p\u003e \u003cp\u003e7.5.1 Integrating Experimental Dataset into a Topological Analysis 227\u003c\/p\u003e \u003cp\u003e7.5.2 Integrating Expression or Activation Levels as Nodes Attributes 228\u003c\/p\u003e \u003cp\u003e7.5.3 Edge Attributes as Distance in a Computation 228\u003c\/p\u003e \u003cp\u003e7.6 Network Analysis Software 229\u003c\/p\u003e \u003cp\u003e7.6.1 Cytoscape and Its Apps 229\u003c\/p\u003e \u003cp\u003e7.6.1.1 structureViz\/RINalyzer 231\u003c\/p\u003e \u003cp\u003e7.6.1.2 CentiScaPe 231\u003c\/p\u003e \u003cp\u003e7.6.1.3 PesCa 231\u003c\/p\u003e \u003cp\u003e7.6.1.4 Interference 231\u003c\/p\u003e \u003cp\u003e7.6.1.5 clusterMaker2 232\u003c\/p\u003e \u003cp\u003e7.6.1.6 chemViz 233\u003c\/p\u003e \u003cp\u003e7.6.2 Other Tools 233\u003c\/p\u003e \u003cp\u003e7.6.2.1 Gephi 233\u003c\/p\u003e \u003cp\u003e7.6.2.2 D3.js 234\u003c\/p\u003e \u003cp\u003e7.6.2.3 VisANT 234\u003c\/p\u003e \u003cp\u003e7.7 Conclusions 236\u003c\/p\u003e \u003cp\u003eReferences 236\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 A Toxicological Application of Signal Transduction: Early Cellular Changes Can Be Indicative of Toxicity 239\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJulie Vrana Miller, Nicole Prince, Julia A. Mouch, \u003c\/i\u003eand \u003ci\u003eJonathan W. Boyd\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 239\u003c\/p\u003e \u003cp\u003e8.2 Classification of Toxic Agent and Exposure Effects: A Toxicological Perspective 240\u003c\/p\u003e \u003cp\u003e8.2.1 Dose–Response for Chemical Exposure Toxicity Testing and Risk Assessment 240\u003c\/p\u003e \u003cp\u003e8.2.2 Chemical Mixtures 241\u003c\/p\u003e \u003cp\u003e8.2.3 Mode of Action Versus Mechanism of Action 242\u003c\/p\u003e \u003cp\u003e8.3 Early Cellular Changes Post‐exposure 244\u003c\/p\u003e \u003cp\u003e8.3.1 Intracellular Signaling Perturbations Associated with Exposure 245\u003c\/p\u003e \u003cp\u003e8.3.2 Bioenergetic Changes Post‐exposure 248\u003c\/p\u003e \u003cp\u003e8.3.3 Time Scale of Exposure Effects 249\u003c\/p\u003e \u003cp\u003e8.4 Experimentally Testing Early Cellular Changes that May Contribute to Exposure Sensing and Response 250\u003c\/p\u003e \u003cp\u003e8.4.1 Paradigm Shift Toward \u003ci\u003eIn Vitro\u003c\/i\u003e Cell Culture 250\u003c\/p\u003e \u003cp\u003e8.4.2 Real‐Time \u003ci\u003eIn Vitro\u003c\/i\u003e Assays to Measure Early Cellular Changes 251\u003c\/p\u003e \u003cp\u003e8.4.2.1 Using NADH and Oxygen Consumption to Predict ATP Generation 252\u003c\/p\u003e \u003cp\u003e8.4.3 Prediction of Posttranslational Phosphorylation Response for Mixtures 253\u003c\/p\u003e \u003cp\u003e8.4.3.1 Using Bliss Independence (Response Addition) to Predict Relative Phosphorylation During Critical Signaling Events 253\u003c\/p\u003e \u003cp\u003eReferences 256\u003c\/p\u003e \u003cp\u003eAppendix A 262\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Future Research in Signaling 267\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJonathan W. Boyd, Nicole Prince, \u003c\/i\u003eand\u003ci\u003e Marc Birringer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Translational Research and a Spatiotemporal Understanding of Signal Transduction 267\u003c\/p\u003e \u003cp\u003e9.2 Integrating Second Messengers into Signal Transduction 270\u003c\/p\u003e \u003cp\u003e9.3 Understanding Crosstalk in Signal Transduction 272\u003c\/p\u003e \u003cp\u003e9.4 Posttranslational Modifications (PTMs) and Target Identification in Signal Transduction 274\u003c\/p\u003e \u003cp\u003e9.5 Epigenetic Endpoints in Signal Transduction 276\u003c\/p\u003e \u003cp\u003e9.6 The Integration of Nutrition and Signal Transduction 278\u003c\/p\u003e \u003cp\u003e9.6.1 Cellular AMPK Signaling 281\u003c\/p\u003e \u003cp\u003e9.6.2 Cellular TOR Signaling 282\u003c\/p\u003e \u003cp\u003e9.6.3 Gut Microbiota 282\u003c\/p\u003e \u003cp\u003e9.6.4 The Integration of Endocrine Gut Signaling 283\u003c\/p\u003e \u003cp\u003eReferences 284\u003c\/p\u003e \u003cp\u003eIndex 291\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48738356101463,"sku":"9781119060260","price":112.46,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119060260.jpg?v=1723811967"},{"product_id":"cell-cell-junctions-second-edition-9781621821519","title":"Cell-Cell Junctions, Second Edition","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Cold Spring Harbor Laboratory Press,U.S.","offers":[{"title":"Default Title","offer_id":48740661133655,"sku":"9781621821519","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"biocatalysis-in-organic-synthesis-the-retrosynthesis-approach-9781782625308","title":"Biocatalysis in Organic Synthesis: The","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe application of biocatalysis in organic synthesis is rapidly gaining popularity amongst chemists. Compared to traditional synthetic methodologies biocatalysis offers a number of advantages in terms of enhanced selectivity (chemo-, regio-, stereo-), reduced environmental impact and lower cost of starting materials. Together these advantages can contribute to more sustainable manufacturing processes across a wide range of industries ranging from pharmaceuticals to biofuels. The biocatalytic toolbox has expanded significantly in the past five years and given the current rate of development of new engineered biocatalysts it is likely that the number of available biocatalysts will double in the next few years.  This textbook gives a comprehensive overview of the current biocatalytic toolbox and also establishes new guidelines or rules for “biocatalytic retrosynthesis”. Retrosynthesis is a well known and commonly used technique whereby organic chemists start with the structure of their target molecule and generate potential starting materials and intermediates through a series of retrosynthetic disconnections. These disconnections are then used to devise a forward synthesis, in this case using biocatalytic transformations in some of the key steps. Target molecules are disconnected with consideration for applying biocatalysts, as well as chemical reagents and chemocatalysts, in the forward synthesis direction. Using this textbook, students will be able to place biocatalysis within the context of other synthetic transformations that they have learned earlier in their studies. This additional awareness of biocatalysis will equip students for the modern world of organic synthesis where biocatalysts play an increasingly important role. In addition to guidelines for identifying where biocatalysts can be applied in organic synthesis, this textbook also provides examples of current applications of biocatalysis using worked examples and case studies. Tutorials enable the reader to practice disconnecting target molecules to find the ‘hidden’ biocatalytic reactions which can be applied in the synthetic direction. The book contains a complete description of the current biocatalyst classes that are available for use and also suggests areas where new enzymes are likely to be developed in the next few years. This textbook is an essential resource for lecturers and students studying synthetic organic chemistry. It also serves as a handy reference for practicing chemists who wish to embed biocatalysis into their synthetic toolbox.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction and Aims of the Book; Biocatalysis Basics and Principles; Hydrolysis; Reverse Hydrolysis: Reduction; Oxidation; C–X Bond Formation; C–C Bond Formation, Miscellaneous Biocatalysts; Biocatalytic Disconnections and Functional Group Interconversions; Comparison of Different Biocatalytic Routes to Target Molecules; Applications of Biocatalytic Retrosynthesis","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741113921879,"sku":"9781782625308","price":47.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781782625308.jpg?v=1720056617"},{"product_id":"basic-chemistry-for-life-science-students-and-professionals-introduction-to-organic-compounds-and-drug-molecules-9781839167874","title":"Basic Chemistry for Life Science Students and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eOrganic chemistry plays a vital role in the pharmaceutical industry. Knowledge of organic compounds is used to inform research and further the discovery and development of new medicines. Likewise, organic chemistry is fundamental to understanding biological reactions, mechanisms and all life sciences in general.    Basic Chemistry for Life Science Students and Professionals is an ideal introduction to organic chemistry in the context of the life sciences and pharmacy related disciplines; utilising drug molecules to illustrate the chemical basis of their efficacy and interaction with biological targets. This book builds upon the basic concepts of organic chemistry to develop the reader’s understanding of the importance of organic chemistry to the life sciences from natural product sources, their synthesis, and approaches to drug discovery.    Ideal for undergraduate students in the natural sciences, this book is also an excellent primer for postgraduates in a variety of disciplines including forensic science and allied-health programmes as well as professionals working in related fields seeking a comprehensive introduction to organic chemistry in the context of pharmaceuticals.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction to Organic Compounds and Covalent Bonding; Polarity of Bonds, Electronegativity, and Intermolecular Forces; Types of Organic Compounds, Nomenclature, and Basic Reactions: Alkanes and Cycloalkanes; Types of Organic Compounds, Nomenclature, and Basic Reactions: Alkenes, Cycloalkenes and Other Unsaturated Hydrocarbons; 5 Types of Organic Compounds, Nomenclature, and Basic Reactions: Functional Groups; Isomerism in Organic Compounds and Drug Molecules: Chemistry and Significance in Biology; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Amino Acids to  Proteins; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Monosaccharides to Complex Carbohydrates; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Fatty Acids to Complex Lipids and Fat; Organic Macromolecules in Cellular Structures, Metabolism, and as Drugs: From Nucleotides to Nucleic Acids; Physicochemical Properties of Organic Compounds and Drug Molecules; Drug-Target Interactions; Structural Diversity and Sources of Drugs: From Nature to Synthetic and Recombinant DNA Technology","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741985091927,"sku":"9781839167874","price":42.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781839167874.jpg?v=1720059564"},{"product_id":"bird-and-reptile-species-in-environmental-risk-assessment-strategies-9781839167102","title":"Bird and Reptile Species in Environmental Risk","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWith the expansion of human settlements and the environmental changes brought on by human activity and pollutants, toxicology and risk assessment of bird and reptile species is becoming increasingly of interest to toxicologists involved in environmental research. This book focuses specifically on environmental risk assessment in non-conventional bird and reptile species.   Bird and Reptile Species in Environmental Risk Assessment Strategies will be an ideal companion to toxicologists and ecologists interested in risk assessment in the environments of birds and reptiles, particularly those with an interest in the impact introduced by human activity. The book will also be of interest to those working in conservation biology, biological invasion, biocontrol and habitat management.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eGeneral Aspects – Current and Further Perspectives; Development of Aquatic Bird Indicators of Sublethal Mercury Exposure and Risk in Wild Populations of Water Birds in the Everglades;The Importance of Ecological Traits in Assessing Seabird Vulnerability to Environmental Risks;A Review on Levels and Distribution Pattern of Organochlorine Pesticides in Eggs of Wild Birds in India;Impacts of Agricultural Intensification on Farmland Birds and Risk Assessment of Pesticide Seed Treatments;Teratological Effects of Pesticides in Reptiles - A Review;Combined Impact of Pesticides and other Environmental Stressors on Reptile Diversity in Irrigation Poinds Compared to other Animal Taxa;Current Progress in Developing Standardized Methods for Reptilian Toxicity Testing to Inform Ecological Risk Assessment;Morphological and Molecular Evidence of Active Principle Glyphosphate Toxicity on the Liver of the Field Lizard Podarcis siculus;What is Caiman latirostris teaching us about Endocrine Disruptors;The Broad Snouted Caiman (Caiman latirostris): A Model Species for Environmental Pesticide Contamination Assessment through Molecular Markers; Epilogue and Final Remarks","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48741985157463,"sku":"9781839167102","price":999.99,"currency_code":"GBP","in_stock":false}]},{"product_id":"turn-on-and-tune-in-psychedelics-narcotics-and-euphoriants-9781847559098","title":"Turn On and Tune In: Psychedelics, Narcotics and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eTimothy Leary's advice to \"tune in, turn on and drop out\" was a 1960s exhortation to experiment with LSD, but humans had been consuming ergot alkaloids related to lysergic acid diethylamide for at least a thousand years. Opium has been around even longer with its medicinal uses being known to the Ancient Sumerians as long ago as 3400 BC. This is the first book to cover all of the major psychoactive drugs (both natural and synthetic) in one volume, and the only one to cover all aspects of these drugs from their anthropological and sociological influences through to their chemistry and pharmacology. It covers a range of substances including LSD, opium, heroin, cocaine, cannabis, peyote, belladonna, mandrake, and absinthe. The book is highly readable and concentrates on the characters (e.g. authors, painters, pop stars, hippies, politicians and drug barons), both famous and infamous, who have ensured that psychoactive drugs hold an enduring fascination and interest for everyone. The basic chemistry and pharmacological activity covered together with a brief account of useful drugs that have emerged from a study of the psychoactive ones.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"This fascinating book...introduces us to the history of the various groups of mind-altering chemicals, beginning with ergot and LSD.\"\"The book is beautifully produced and well illustrated.\"\"...would make excellent background reading for pharmacy students.\" * The Pharmaceutical Journal, April 2010 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eChapter 1: From Ergotism to LSD; Chapter 2: From Opium to Heroin; Chapter 3: Coca and Cocaine; Chapter 4: Cannabis: Hashish, Marijuana, Chaeas and Bhang; Chapter 5: Belladonna, Mandrake and Daturas; Chapter 6: Peyote and Amphetamines; Chapter 7: Fly Agaric; Chapter 8: Absinthe","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":48742217122135,"sku":"9781847559098","price":23.7,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781847559098.jpg?v=1720060504"},{"product_id":"fruit-oils-chemistry-and-functionality-9783030124755","title":"Fruit Oils: Chemistry and Functionality","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eFruit Oils: Chemistry and Functionality\u003c\/i\u003e presents a comprehensive overview of recent advances in the chemistry and functionality of lipid bioactive phytochemicals found in fruit oils. The chapters in this text examine the composition, physicochemical characteristics and organoleptic attributes of each of the major fruit oils. The nutritional quality, oxidative stability, and potential food and non-foodapplications of these oils are also extensively covered. The potential health benefits of the bioactive lipids found in these fruit oils are also a focus of this text. For each oil presented, the levels of \u003ci\u003eomega\u003c\/i\u003e-9, \u003ci\u003eomega\u003c\/i\u003e-6 and \u003ci\u003eomega\u003c\/i\u003e-3 fatty acids are specified, indicating the level of health-promoting traits exhibited in each. \u003c\/p\u003e\u003cp\u003eThe oils and fats extracted from fruits generally differ from one another both in terms of their major and minor bioactive constituents. The methods used to extract oils and fats as well as the processing techniques such as refining, bleaching and deodorization affect their major and minor constituents. In addition, different post-processing treatments of fruit oils and fats may alert or degrade important bioactive constituents. Treatments such as heating, frying, cooking and storage and major constituents such as sterols and tocols are extensively covered in this text. \u003c\/p\u003e\u003cp\u003eAlthough there have been reference works published on the composition and biological properties of lipids from oilseeds, there is currently no book focused on the composition and functionality of fruit oils. \u003ci\u003eFruit Oils: Chemistry and Functionality\u003c\/i\u003e aims to fill this gap for researchers, presenting a detailed overview of the chemical makeup and functionality of all the important fruit oils.         \u003cbr\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e            \u003c\/p\u003e  \u003cp\u003e            \u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eIntroduction to fruit oils: chemistry and 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oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eAlmond (\u003ci\u003ePrunus dulcis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePistachio (\u003ci\u003ePistacia vera\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eWalnut (\u003ci\u003eJuglans regia\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eChestnut (\u003ci\u003eCastanea sativa)\u003c\/i\u003e oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePassion (\u003ci\u003ePassiflora edulis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGac (\u003ci\u003eMomordica cochinchinensis\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePomegranate (\u003ci\u003ePunica granatum\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGrape (\u003cem\u003eVitis vinifera\u003c\/em\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eApple (\u003ci\u003eMalus pumila\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eWatermelon (\u003ci\u003eCitrullus lanatus\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eAmla (\u003ci\u003ePhyllanthus emblica\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eBuriti (\u003ci\u003eMauritia flexuosa\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eBael (\u003ci\u003eAegle marmelos\u003c\/i\u003e )oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eSandalwood (\u003ci\u003eSantalum album\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCoconut (\u003ci\u003eCocos nucifera\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eCitrus oils\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eKiwifruit (\u003ci\u003eActinidia deliciosa\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eGuava (\u003ci\u003ePsidium guajava\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eDate palm (\u003ci\u003ePhoenix dactylifera\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eApricot (\u003ci\u003ePrunus armeniac\u003c\/i\u003ea) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003eMangongo\/manketti  (\u003ci\u003eSchinziophyton rautanenii\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ePapaya (\u003ci\u003eCarica papaya\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003ci\u003eCelastrus paniculatus\u003c\/i\u003e\u003c\/b\u003e\u003ci\u003e \u003c\/i\u003e\u003cb\u003eoil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003ci\u003eSemecarpus anacardium\u003c\/i\u003e oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003ekachnar (\u003ci\u003eBauhinia purpurea\u003c\/i\u003e) oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cp\u003e\u003cb\u003eButtercup tree [\u003ci\u003eMadhuca\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e  \u003cb\u003e\u003ci\u003elongifolia\u003c\/i\u003e (Koenig)] oil\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743024099671,"sku":"9783030124755","price":75.99,"currency_code":"GBP","in_stock":true}]},{"product_id":"strigolactones-biology-and-applications-9783030121525","title":"Strigolactones - Biology and Applications","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book describes the exciting biology and chemistry of strigolactones. Outgrowth of shoot branches? Development of lateral roots? Interactions with beneficial microorganisms? Avoiding parasitic plants? Responding to drought conditions? These important “decisions” that plants make are all regulated by a group of hormones called strigolactones.\u003cbr\u003eThe latest research has yielded a number of new biological concepts, such as a redefinition of plant hormones and their crosstalk, new functional diversity of receptors, hormonal “smoke and mirrors,” core signaling pathways, and even phloem transport of receptor proteins. Another important aspect of strigolactones is the related synthetic chemistry, which could pave the way for a variety of potential applications in agriculture and medicine.\u003cbr\u003eThe book explains in detail the role that strigolactones play in plant development, and addresses the interaction of plants with soil biota and abiotic stress conditions, prospects of strigolactone biochemistry and evolution, and chemical synthesis of natural strigolactones and analogs, together with their potential applications. Including a glossary and end-of-chapter synopses to aid in comprehension, it offers a valuable asset for teachers, lecturers and (post-) graduate students in biology, agronomy and related areas..\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1. Strigolactone natural biosynthesis.- 2. Strigolactones as plant hormones.- 3. Strigolactones and parasitic plants.- 4. Strigolactones and the soil microbiota.- 5. Strigolactones likes and evolution.- 6. Strigolactones synthetic chemistry and applications.- 7. Synopses.","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743024197975,"sku":"9783030121525","price":40.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783030121525.jpg?v=1720063789"},{"product_id":"introduction-to-antibody-engineering-9783030546298","title":"Introduction to Antibody Engineering","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed.\u003c\/p\u003e\u003cp\u003eThe book’s content is based on lectures for the specializations “Protein Engineering” and “Medical Biotechnology” within the Master’s curriculum in “Biotechnology.” The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field.\u003c\/p\u003e\u003cp\u003e The book addresses Master- and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743040123223,"sku":"9783030546298","price":63.06,"currency_code":"GBP","in_stock":true}]},{"product_id":"a-practical-guide-to-protein-engineering-9783030568979","title":"A Practical Guide to Protein Engineering","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eThis textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a career as a protein engineer. 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Unlike a kit chemistry approach, this book provides a breadth of information necessary for junior or non-expert researchers to learn and apply these techniques in their work. An accessible, indispensable how-to guide for researchers in immunology, molecular biology, zoology, forensic science, genetics, botany, neuroscience, physiology, and others.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e1-Basic idea about nucleic acids for non-experts\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e2-General steps during isolation of DNA and RNA\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e3-Phenol-chloroform DNA isolation method\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e4-RNA isolation by the guanidinium-acid-phenol method\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e5-Spin column-based isolation of nucleic acid\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e6-Isolation of plasmid DNA by alkaline lysis\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e7-DNA Isolation by Hydrophilic Ionic Liquid Treatment\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  8-Lithium Chloride based isolation of DNA and RNA\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e9-Isolation of Bacteriophage DNA by PEG Method\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e10-DNA isolation by Chelex Method\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e11-DNA isolation by Lysozyme and Proteinase K\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e12-Salting-out method for blood samples\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e13-CTAB or SDS based isolation of plant’s DNA\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e14-DNA extraction by spooling method\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e15-Magnetic bead-based nucleic acid isolation\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e16-Density gradient-based nucleic acid isolation\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e17-DNA extraction from agarose gel though paper-strips\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e18-TRANSFORMATION OR GENETIC MODIFICATION OF CELLS\/ORGANISMS\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e19-GENE CLONING AND VECTORS\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e20-POLYMERASE CHAIN REACTION (PCR)\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e21-Southern and Northern Blotting\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e22-GENOME MAPPING\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e23-Applications of DNA Sequencing Technologies for Current Research\u003c\/p\u003e","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":48743060635991,"sku":"9783030942328","price":66.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783030942328.jpg?v=1720063936"},{"product_id":"protein-folding-an-introduction-9783319008813","title":"Protein Folding: An Introduction","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis snapshot volume is designed to provide a smooth entry into the field of protein folding. Presented in a concise manner, each section introduces key concepts while providing a brief overview of the relevant literature. Outlook subsections will pinpoint specific aspects related to emerging methodologies, concepts and trends.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eProtein Structure: How is structure maintained?.- Protein Folding: Why is structure acquired?.- Folding Kinetics and Mechanisms: How is structure acquired?.- Protein Misfolding: Why proteins misbehave?.- Methods for Protein Folding.\u003c\/p\u003e","brand":"Springer International Publishing AG","offers":[{"title":"Default Title","offer_id":48743091142999,"sku":"9783319008813","price":39.59,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783319008813.jpg?v=1720064070"},{"product_id":"modern-biophysical-chemistry-detection-and-analysis-of-biomolecules-9783527337736","title":"Modern Biophysical Chemistry: Detection and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis updated and up-to-date version of the first edition continues with the really interesting stuff to spice up a standard biophysics and biophysical chemistry course. All relevant methods used in current cutting edge research including such recent developments as super-resolution microscopy and next-generation DNA sequencing techniques, as well as industrial applications, are explained. The text has been developed from a graduate course taught by the author for several years, and by presenting a mix of basic theory and real-life examples, he closes the gap between theory and experiment.\u003cbr\u003e The first part, on basic biophysical chemistry, surveys fundamental and spectroscopic techniques as well as biomolecular properties that represent the modern standard and are also the basis for the more sophisticated technologies discussed later in the book. The second part covers the latest bioanalytical techniques such as the mentioned super-resolution and next generation sequencing methods, confocal fluorescence microscopy, light sheet microscopy, two-photon microscopy and ultrafast spectroscopy, single molecule optical, electrical and force measurements, fluorescence correlation spectroscopy, optical tweezers, quantum dots and DNA origami techniques. Both the text and illustrations have been prepared in a clear and accessible style, with extended and updated exercises (and their solutions) accompanying each chapter.\u003cbr\u003e Readers with a basic understanding of biochemistry and\/or biophysics will quickly gain an overview of cutting edge technology for the biophysical analysis of proteins, nucleic acids and other biomolecules and their interactions. Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented. Questions of differing complexity testing the reader's understanding can be found at the end of each chapter with clearly described solutions available on the Wiley-VCH textbook homepage under: www.wiley-vch.de\/textbooks\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction: What is Biophysical Chemistry? -\u003cbr\u003e An Example from Drug Screening\u003cbr\u003e \u003cbr\u003e PART I: Basic Methods in Biophysical Chemistry\u003cbr\u003e \u003cbr\u003e BASIC OPTICAL PRINCIPLES\u003cbr\u003e Introduction\u003cbr\u003e What Does the Electronic Structure of Molecules Look Like? Orbitals, Wave Functions and Bonding Interactions\u003cbr\u003e How Does Light Interact with Molecules? Transition Densities and the Transition Dipole Moment\u003cbr\u003e Absorption Spectra of Molecules in Liquid Environments. Vibrational Excitation and the Franck-Condon Principle\u003cbr\u003e What Happens After Molecules have Absorbed Light? Fluorescence, Nonradiative Transitions and the Triplet State\u003cbr\u003e Quantitative Description of all Processes: Quantum Efficiencies, Kinetics of Excited State Populations and the Jablonski Diagram Problems\u003cbr\u003e \u003cbr\u003e OPTICAL PROPERTIES OF BIOMOLECULES\u003cbr\u003e Introduction\u003cbr\u003e Experimental Determination of Absorption and Fluorescence Spectra\u003cbr\u003e Optical Properties of Proteins and DNA\u003cbr\u003e Optical Properties of Important Cofactors\u003cbr\u003e \u003cbr\u003e BASIC FLUORESCENCE TECHNQUES\u003cbr\u003e Introduction\u003cbr\u003e Fluorescent Labelling and Linking Techniques\u003cbr\u003e Fluorescence Detection Techniques\u003cbr\u003e Fluorscence Polarization Anisotropy\u003cbr\u003e Forster Resonance Energy Transfer\u003cbr\u003e Fluorescence Kinetics\u003cbr\u003e Fluorescence Recovery after Photobleaching\u003cbr\u003e Biochemiluminescence\u003cbr\u003e \u003cbr\u003e CHIROPTICAL AND SCATTERING METHODS\u003cbr\u003e Chiroptical Methods\u003cbr\u003e Light Scattering\u003cbr\u003e Vibrational Spectra of Biomolecules\u003cbr\u003e \u003cbr\u003e MAGNETIC RESONANCE TECHNIQUES\u003cbr\u003e Nuclear Magnetic Resonance of Biomolecules\u003cbr\u003e Electron Paramagnetic Resonance\u003cbr\u003e \u003cbr\u003e MASS SPECTROMETRY\u003cbr\u003e Introduction\u003cbr\u003e MALDI-TOF\u003cbr\u003e ESI-MS\u003cbr\u003e Structural and Sequence Analysis Using Mass Spectrometry\u003cbr\u003e \u003cbr\u003e PART II: Advanced Methods in Biophysical Chemistry\u003cbr\u003e \u003cbr\u003e FLUORESCENCE MICROSCOPY\u003cbr\u003e Introduction\u003cbr\u003e Conventional Fluorescence Microscopy\u003cbr\u003e Total Internal Reflection Fluorescence Microscopy\u003cbr\u003e Light-Sheet Microscopy\u003cbr\u003e \u003cbr\u003e SUPER-RESOLUTION FLUORESCENCE MICROSCOPY\u003cbr\u003e Stimulated Emission Depletion (STED) Microscopy\u003cbr\u003e Photoactivated Localization Microscopy (PALM) and Stochastic Optical Reconstruction Microscopy (STORM)\u003cbr\u003e 3D Super-Resolution Fluorescence Microscopy\u003cbr\u003e Imaging of Live Cells\u003cbr\u003e Multicolour Super-Resolution Fluorescence Microscopy\u003cbr\u003e Structured Illumination Microscopy\u003cbr\u003e SOFI\u003cbr\u003e Final Comparison\u003cbr\u003e \u003cbr\u003e SINGLE-BIOMOLECULE TECHNIQUES\u003cbr\u003e Introduction\u003cbr\u003e Optical Single-Molecule Detection\u003cbr\u003e Fluorescence Correlation Spectroscopy\u003cbr\u003e Optical Tweezers\u003cbr\u003e Atomic Force Microscopy of Biomolecules\u003cbr\u003e Patch Clamping\u003cbr\u003e \u003cbr\u003e ULTRAFAST- AND NONLINEAR SPECTROSCOPY\u003cbr\u003e Introduction\u003cbr\u003e Nonlinear Microscopy and Spectroscopy\u003cbr\u003e Ultrafast Spectroscopy\u003cbr\u003e \u003cbr\u003e DNA SEQUENCING AND NEXT-GENERATION SEQUENCING METHODS\u003cbr\u003e Sanger Method\u003cbr\u003e Next-Generation Sequencing Methods\u003cbr\u003e \u003cbr\u003e SPECIAL TECHNIQUES\u003cbr\u003e Introduction\u003cbr\u003e Fluorescing Nanoparticles\u003cbr\u003e Surface Plasmon Resonance Detection\u003cbr\u003e DNA Origami\u003cbr\u003e DNA Microarrays\u003cbr\u003e Flow Cytometry\u003cbr\u003e Fluorescence In Situ Hybridization\u003cbr\u003e Microspheres and Nanospheres\u003cbr\u003e \u003cbr\u003e ASSAY DEVELOPMENT, READERS AND HIGH-THROUGHPUT SCREENING\u003cbr\u003e Introduction\u003cbr\u003e Assay Development and Assay Quality\u003cbr\u003e Microtitre Plates and Fluorescence Readers\u003cbr\u003e Application Example: Drug Discovery and High-Throughput Screening\u003cbr\u003e \u003cbr\u003e Index\u003cbr\u003e \u003cbr\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":48743118569815,"sku":"9783527337736","price":51.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783527337736.jpg?v=1720064192"},{"product_id":"bioanalytics-analytical-methods-and-concepts-in-biochemistry-and-molecular-biology-9783527339198","title":"Bioanalytics: Analytical Methods and Concepts in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eAnalytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids.\u003cbr\u003e \u003cbr\u003e The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. \u003cbr\u003e \u003cbr\u003e The following techniques are covered in detail:\u003cbr\u003e \u003cbr\u003e - Purification and determination of proteins\u003cbr\u003e - Measuring enzymatic activity\u003cbr\u003e - Microcalorimetry\u003cbr\u003e - Immunoassays, affinity chromatography and other immunological methods\u003cbr\u003e - Cross-linking, cleavage, and chemical modification of proteins\u003cbr\u003e - Light microscopy, electron microscopy and atomic force microscopy\u003cbr\u003e - Chromatographic and electrophoretic techniques\u003cbr\u003e - Protein sequence and composition analysis\u003cbr\u003e - Mass spectrometry methods\u003cbr\u003e - Measuring protein-protein interactions\u003cbr\u003e - Biosensors\u003cbr\u003e - NMR and EPR of biomolecules\u003cbr\u003e - Electron microscopy and X-ray structure analysis\u003cbr\u003e - Carbohydrate and lipid analysis\u003cbr\u003e - Analysis of posttranslational modifications\u003cbr\u003e - Isolation and determination of nucleic acids\u003cbr\u003e - DNA hybridization techniques\u003cbr\u003e - Polymerase chain reaction techniques\u003cbr\u003e - Protein sequence and composition analysis\u003cbr\u003e - DNA sequence and epigenetic modification analysis\u003cbr\u003e - Analysis of protein-nucleic acid interactions\u003cbr\u003e - Analysis of sequence data\u003cbr\u003e - Proteomics, metabolomics, peptidomics and toponomics\u003cbr\u003e - Chemical biology\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface XV\u003c\/p\u003e \u003cp\u003eIntroduction XIX\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Protein Analytics 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Protein Purification 3\u003c\/p\u003e \u003cp\u003e2 Protein determination 23\u003c\/p\u003e \u003cp\u003e3 Enzyme Activity Testing 35\u003c\/p\u003e \u003cp\u003e4 Microcalorimetry 47\u003c\/p\u003e \u003cp\u003e5 Immunological Techniques 63\u003c\/p\u003e \u003cp\u003e6 Chemical Modification of Proteins and Protein Complexes 107\u003c\/p\u003e \u003cp\u003e7 Spectroscopy 131\u003c\/p\u003e \u003cp\u003e8 Light Microscopy Techniques – Imaging 181\u003c\/p\u003e \u003cp\u003e9 Cleavage of Proteins 207\u003c\/p\u003e \u003cp\u003e10 Chromatographic Separation Methods 219\u003c\/p\u003e \u003cp\u003e11 Electrophoretic Techniques 243\u003c\/p\u003e \u003cp\u003e12 Capillary Electrophoresis 275\u003c\/p\u003e \u003cp\u003e13 Amino Acid Analysis 301\u003c\/p\u003e \u003cp\u003e14 Protein Sequence Analysis 313\u003c\/p\u003e \u003cp\u003e15 Mass Spectrometry 329\u003c\/p\u003e \u003cp\u003e16 Protein–Protein Interactions 381\u003c\/p\u003e \u003cp\u003e17 Biosensors 419\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II 3D Structure Determination 431\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18 Magnetic Resonance Spectroscopy of Biomolecules 433\u003c\/p\u003e \u003cp\u003e19 Electron Microscopy 485\u003c\/p\u003e \u003cp\u003e20 Atomic Force Microscopy 519\u003c\/p\u003e \u003cp\u003e21 X-Ray Structure Analysis 529\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Peptides, Carbohydrates, and Lipids 553\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22 Analytics of Synthetic Peptides 555\u003c\/p\u003e \u003cp\u003e23 Carbohydrate Analysis 571\u003c\/p\u003e \u003cp\u003e24 Lipid Analysis 613\u003c\/p\u003e \u003cp\u003e25 Analysis of Post-translational Modifications: Phosphorylation and Acetylation of Proteins 645\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Nucleic Acid Analytics 663\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e26 Isolation and Purification of Nucleic Acids 665\u003c\/p\u003e \u003cp\u003e27 Analysis of Nucleic Acids 681\u003c\/p\u003e \u003cp\u003e28 Techniques for the Hybridization and Detection of Nucleic Acids 719\u003c\/p\u003e \u003cp\u003e29 Polymerase Chain Reaction 755\u003c\/p\u003e \u003cp\u003e30 DNA Sequencing 785\u003c\/p\u003e \u003cp\u003e31 Analysis of Epigenetic Modifications 817\u003c\/p\u003e \u003cp\u003e32 Protein–Nucleic Acid Interactions 831\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V Functional and Systems Analytics 873\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e33 Sequence Data Analysis 875\u003c\/p\u003e \u003cp\u003e34 Analysis of Promoter Strength and Nascent RNA Synthesis 895\u003c\/p\u003e \u003cp\u003e35 Fluorescent In Situ Hybridization in Molecular Cytogenetics 917\u003c\/p\u003e \u003cp\u003e36 Physical and Genetic Mapping of Genomes 925\u003c\/p\u003e \u003cp\u003e37 DNA-Microarray Technology 945\u003c\/p\u003e \u003cp\u003e38 The Use of Oligonucleotides as Tools in Cell Biology 959\u003c\/p\u003e \u003cp\u003e39 Proteome Analysis 977\u003c\/p\u003e \u003cp\u003e40 Metabolomics and Peptidomics 1023\u003c\/p\u003e \u003cp\u003e41 Interactomics – Systematic Protein–Protein Interactions 1033\u003c\/p\u003e \u003cp\u003e42 Chemical Biology 1041\u003c\/p\u003e \u003cp\u003e43 Toponome Analysis 1057\u003c\/p\u003e \u003cp\u003eAppendix 1: Amino Acids and Posttranslational Modifications 1073\u003c\/p\u003e \u003cp\u003eAppendix 2: Symbols and Abbreviations 1075\u003c\/p\u003e \u003cp\u003eAppendix 3: Standard Amino Acids (three and one letter code) 1081\u003c\/p\u003e \u003cp\u003eAppendix 4: Nucleic Acid Bases 1083\u003c\/p\u003e \u003cp\u003eIndex 1085\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48743119126871,"sku":"9783527339198","price":67.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783527339198.jpg?v=1720064193"},{"product_id":"the-hot-blooded-insects-strategies-and-mechanisms-of-thermoregulation-9783662103425","title":"The Hot-Blooded Insects: Strategies and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\"From one man's persistent and elegant probing of the temperature biology of bees, we have been led to a deeper understanding of the whole biology of many insect taxa, and of their interactions with ecological and environmental stresses: all who work at the interfaces of physiology, ecology and behaviour have cause to be grateful, and all should certainly read this book.\" (Trends in Ecology \u0026amp; Evolution) \"An outstanding source of information, and can be read with profit and satisfaction by the professional biologist and interested amateur alike.\" (Nature)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"From one man's persistent and elegant probing of the temperature biology of bees, we have been led to a deeper understanding of the whole biology of many insect taxa, and of their interactions with ecological and environmental stresses: all who work at the interfaces of physiology, ecology and behaviour have cause to be grateful, and all should certainly read this book.\" (Trends in Ecology \u0026amp; Evolution) \"An outstanding source of information, and can be read with profit and satisfaction by the professional biologist and interested amateur alike.\" (Nature)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePrologue.- 1 Night-Flying Moths.- 2 Butterflies and Wings.- 3 Dragonflies Now and Then.- 4 Grasshoppers and Other Orthoptera.- 5 Beetles Large and Small.- 6 Bumblebees Out in the Cold.- 7 Tropical Bees.- 8 Hot-Headed Honeybees.- 9 The Tolerance of Ants.- 10 Wasps and the Heat of Battle.- 11 Flies of All Kinds.- 12 Sweating Cicadas.- 13 Warm Caterpillars and Hot Maggots.- 14 Fever.- 15 Cold Jumpers.- 16 Social Thermoregulation.- Summary.- References.- Acknowledgments.- Index of Authors Cited.- General Index.","brand":"Springer-Verlag Berlin and Heidelberg GmbH \u0026 Co. 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It has very unusual properties which makes it the most interesting for research and study.","brand":"World Scientific Publishing Co Pte Ltd","offers":[{"title":"Default Title","offer_id":48743278215511,"sku":"9789811226281","price":33.25,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9789811226281.jpg?v=1720064891"},{"product_id":"nanobiotherapeutic-based-blood-substitutes-9789811228681","title":"Nanobiotherapeutic Based Blood Substitutes","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis definitive volume will provide the reader with up to date information and the most recent science of the fast-evolving area of nanobiotherapeutic-based blood substitutes. Long studied, there are recent updates that make their use in patients more promising, and with one product approved for human use, many more in the pipeline. These include 2nd generations and even third generation ones, the later with enhancement of red blood cell functions. In addition, there are carefully written and referenced updates on the recent history and products in the field, complete with pathophysiologic and pharmacologic studies to validate and verify the efficacy and safety of many of these new products.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eUnlimited Potential of Nanobiotechnology Based Blood Substitutes, Artificial Cells and Nanobiotherapeutics (TMS Chang); General:\tDevelopment and Future of Chinese Transfusion Medicine and Blood Substitutes (J Liu and C Yang); The Clinical Impact of Red Blood Cell Storage: What Have the RCTs Told Us? (CP Stowell); Rational, Evidence-Based Transfusion: A Physiologist's Perspective (GP Biro); Hemoglobin-based Oxygen Carriers, Volume Expansion, Fluid Management and Anemia (TN Estep); Hemoglobin-Based Oxygen Carriers:\tBiotechnology-based Oxygen Carriers (TMS Chang); Hemoglobin-Glutamer 250 (bovine) [HBOC-201, Hemopure (R)] Clinical Use in South Africa and Comprehensive Review of Cardiac Outcomes and Risk\/Benefit in Peer-Reviewed, Indexed Studies in Humans and Animal Models (JS Jahr, K Tseng, AP Brown and GP Dube); Immune Safety Evaluation of Polymerized Porcine Hemoglobin (pPolyHb) - Potential Red Blood Cell Substitutes (H Zhu, K Yan, X Dang, H Huang, E Chen, B Chen, Chan Luo, TMS Chang, P Dai and C Chen); Hemoglobin-Based Oxygen Carriers and Inhaled Nitric Oxide (B Yu and WM Zapol); Hemoglobin-Based Oxygen Carriers and Myocardial Infarction: Assessment of Potential Mechanisms (TN Estep); Insights Into the Possible Mechanisms of Hemoglobin-based Oxygen Carrier-Mediated Bradycardia and Adverse Cardiac Effects Observed in Clinical Trials (HW Kim); Modulation of Oxygen Affinity in Hemoglobin-based Oxygen Carriers (EAM Alomari, L Ronda, S Bettati, A Mozzarelli and S Bruno ); Cysteine Mutations in Recombinant Fetal Hemoglobin Influence Oxidative Side-Reactions (K Kettisen and L Bulow); Analysis of Dimeric A  Subunit Exchange between Bis-PEGylated and Native Hemoglobins (T Matsuhira, K Yamamoto and H Sakai); Ring-Opening Polymerization of Hemoglobin Based on Supramolecular Chemistry (T Matsuhira, K Yamamoto and H Sakai); Hemoglobin-Based Oxygen Carriers with Antioxidant Activities:\tUnraveling of Hemoglobin Oxidative Toxicity: Thirty Years of Investigation (AI Alayash ); A Nanobiotechnologic Therapeutic that Transport Oxygen and Removes Oxygen Radicals (TMS Chang); Effects of Crosslinked Polyhemoglobin-Superoxide Dismutase-Catalase on Blood-Brain Barrier and Brain Edema in a Hemorrhagic Shock Transient Global Ischemia Rat Model (DD Powanda and TMS Chang); Strategies to Decrease the Oxidative Toxicity of Hemoglobin-Based Oxygen Carriers (L Zhoa); Enhancing the Stability of Lumbricus terrestris Erythrocruorin (LtEc) for Use as a Blood Substitute (B Timm and J Elmer); Dual Antioxidant and Pro-Oxidation Effects of Ascorbic Acid on Bovine Hemoglobin (G Chan and TMS Chang); Hemoglobin-Based Oxygen Carriers with Enhancement in Both Antioxidant Functions and Carbon Dioxide Transport:\tSoluble Nanobiotherapeutics with Enhancements of All Three Major Red Blood Cell Functions (TMS Chang); A Novel Nanobiotherapeutical Poly-[Hemoglobin-Superoxide Dismutase-Catalase-Carbonic Anhydrase] with No Cardiac Toxicity for the Resuscitation of a 90-minute Sustained Severe Hemorrhagic Shock Rat Model with Two-third Blood Volume Loss (Y Bian and TMS Chang); Long Term Safety and Immunological Effects of a Nanobiotherapeutic, Bovine Poly-[Hemoglobin-Catalase-Superoxide Dismutase-Carbonic Anhydrase], After Four Weekly 5% Blood Volume Toploading Followed by a Challenge of 30% Exchange Transfusion (G Chen and TMS Chang); Extraction of Superoxide Dismutase, Catalase and Carbonic Anhydrase from Stroma-free Red Blood Cell Hemolysate for the Preparation of the Nanobiotechnological Complex of PolyHemoglobin-superoxide Dismutase-Catalase-Carbonic anhydrase (C Guo, M Gynn and TMS Chang); Temperature Stability of Poly-[hemoglobin-superoxide Dismutase-Catalase-Carbonic anhydrase] in the Form of a Solution or In the Lyophilized Form During Storage at -80 DegreesC, 4 DegreesC, 25 DegreesC and 37 DegreesC or Pasteurization at 70 DegreesC (Y Bian, C Guo and TMS Chang); Biodegradable and Lipid Membrane Nanoencapsulated Nano-Artificial Cells:\tNanotechnology-based Complete Artificial Red Blood Cells (TMS Chang ); Analysis of Polyethylene-Glycol-Polylactide Nano-Dimension Artificial Red Blood Cells in Maintaining Systemic Hemoglobin Levels and Prevention of Methemoglobin Formation (TMS Chang, DD Powanda D and WP Yu); Effects of PEG-PLA-Nano Artificial Cells Containing Hemoglobin on Kidney Function and Renal Histology in Rats (ZC Liu and TMS Chang); Long Term Effects on the Histology and Function of Livers And Spleens in Rats after 33% Toploading of PEG-PLA Nano-Artificial Red Blood Cells (ZC Liu and TMS Chang); Polylactide-Polyethylene Membrane Nanoencapsulated Polyhemoglobin-superoxide Dismutase-Catalase-Carbonic anhydrase. Nano-Artificial Red Blood Cells that Act as O2 and CO2 Carriers with Enhanced Antioxidant Activity (W Gao, Y Bian and TMS Chang); Possibility of Pre-Hospital Resuscitation using Hemoglobin Vesicles for Trauma Hemorrhagic Shock with Coagulopathy - Our Resuscitation Strategy (M Kinoshita and K Hagisawa); Translational Research of Hemoglobin Vesicles (Artificial Red Cells) for a Transfusion Alternative and O2\/CO Therapeutics (H Sakai, H Azuma, H Horinouchi and K Kobayashi); Hemoglobin Vesicles as a Transfusion Alternative for Perioperative Hemorrhage in Thoracic Surgery (M Kohno, R Hashimoto, H Onozawa, K Oiwa, H Horinouchi, H Sakai, K Kobayashi and M Iwazaki); Prevention of Methemoglobin Formation in Artificial Red Cells (Hemoglobin-Vesicles) (H Sakai and M Yamada); Carbon Monoxide-Bound Hemoglobin-Vesicles: Current Facts and Potential Medical Applications (K Taguchi, K Matsumoto, H Sakai, T Maruyama and M Otagiri); Influence of Hemoglobin Vesicles on Immune Function (H Azuma, M Fujihara and H Sakai); Cells, Tissues and Organs Preservation:\tDevelopment of a New HBOC for Liver Allograft Preservation in Combination with Machine Perfusion - Clearing the Wait List (KD Vandegriff, A Malavalli and WR Light); OxyVita (R) Hb: A Step Forward in Delivering Oxygen Carrying Capacity for Therapeutic Applications (H Wollocko, J Harrington, JS Jahr, K Steier and J Wollocko); Functionality of Albumin-Derived Perfluorocarbon-Based Artificial Oxygen Carriers in the Langendorff Heart (KB Ferenz and M Kirsch); Nanobiotherapeutics as Preservation Fluids for Organs and Cells (TMS Chang, W Jiang, F D'Agnillo and S Razack ); Platelet:\tPolyhemoglobin-Fibrinogen: A Novel Oxygen Carrier with Platelet-like Properties in a Hemodilution Setting (NSW Wong and TMS Chang); Megakaryocytes and Platelets from Novel Human Adipose Tissue-Derived Mesenchymal Stem Cells: Development of Cell-based Regenerative Medicine (Y Ono-Uruga, K Tozawa, Y Ikeda and Y Matsubara);","brand":"World Scientific Publishing Co Pte Ltd","offers":[{"title":"Default Title","offer_id":48743278412119,"sku":"9789811228681","price":207.0,"currency_code":"GBP","in_stock":true}]},{"product_id":"how-medicines-work-illustrated-9789811248191","title":"How Medicines Work: Illustrated","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis highly illustrated volume will describe, through clear diagrams and concise text, how the most prescribed, as well as new medicines, work in the body for a broad range of diseases. 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The Reception and Transmission of Extracellular Information.","brand":"Cengage Learning, Inc","offers":[{"title":"Default Title","offer_id":48864476692823,"sku":"9780357728451","price":76.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780357728451.jpg?v=1722272124"},{"product_id":"the-longevity-diet-9780525534075","title":"The Longevity Diet","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e","brand":"Penguin Putnam Inc","offers":[{"title":"Default Title","offer_id":48864989282647,"sku":"9780525534075","price":21.38,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780525534075.jpg?v=1722273401"},{"product_id":"environmental-microbiology-9781118439630","title":"Environmental Microbiology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eNew and expanded for its second edition, \u003ci\u003eEnvironmental Microbiology: From Genomes to Biogeochemistry\u003c\/i\u003e\u003ci\u003e Second Edition\u003c\/i\u003e, is a timely update to a classic text filled with ideas, connections, and concepts that advance an in-depth understanding of this growing segment of microbiology. Core principles are highlighted with an emphasis on the logic of the science and new methods-driven discoveries. Numerous up-to-date examples and applications boxes provide tangible reinforcement of material covered. Study questions at the end of each chapter require students to utilize analytical and quantitative approaches, to define and defend arguments, and to apply microbiological paradigms to their personal interests. Essay assignments and related readings stimulate student inquiry and serve as focal points for teachers to launch classroom discussions. A companion website with downloadable artwork and answers to study questions is also available. \u003c\/p\u003e \u003ci\u003eEnvironmental Microbiology: From Ge\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/i\u003e\u003cp\u003ePreface viii\u003c\/p\u003e \u003cp\u003eAbout the Companion Website x\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Significance, History, and Challenges of Environmental Microbiology 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Core concepts can unify environmental microbiology 1\u003c\/p\u003e \u003cp\u003e1.2 Synopsis of the significance of environmental microbiology 2\u003c\/p\u003e \u003cp\u003e1.3 A brief history of environmental microbiology 6\u003c\/p\u003e \u003cp\u003e1.4 Complexity of our world 10\u003c\/p\u003e \u003cp\u003e1.5 Many disciplines and their integration 13\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Formation of the Biosphere: Key Biogeochemical and Evolutionary Events 25\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Issues and methods in Earth’s history and evolution 26\u003c\/p\u003e \u003cp\u003e2.2 Formation of early planet Earth 26\u003c\/p\u003e \u003cp\u003e2.3 Did life reach Earth from Mars? 30\u003c\/p\u003e \u003cp\u003e2.4 Plausible stages in the development of early life 31\u003c\/p\u003e \u003cp\u003e2.5 Mineral surfaces in marine hydrothermal vents: the early iron\/sulphur world could have driven biosynthesis 35\u003c\/p\u003e \u003cp\u003e2.6 Encapsulation (a key to cellular life) and an alternative (nonmarine) hypothesis for the habitat of precellular life 36\u003c\/p\u003e \u003cp\u003e2.7 A plausible definition of the tree of life’s “Last universal common ancestor” (LUCA) 37\u003c\/p\u003e \u003cp\u003e2.8 The rise of oxygen 39\u003c\/p\u003e \u003cp\u003e2.9 Evidence for oxygen and cellular life in the sedimentary record 39\u003c\/p\u003e \u003cp\u003e2.10 The evolution of oxygenic photosynthesis 42\u003c\/p\u003e \u003cp\u003e2.11 Consequences of oxygenic photosynthesis: molecular oxygen in the atmosphere and large pools of organic carbon 45\u003c\/p\u003e \u003cp\u003e2.12 Eukaryotic evolution: endosymbiotic theory and the blending of traits from \u003ci\u003eArchaea \u003c\/i\u003eand \u003ci\u003eBacteria \u003c\/i\u003e48\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Physiological Ecology: Resource Exploitation by Microorganisms 56\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 The cause of physiological diversity: diverse habitats provide selective pressures over evolutionary time 57\u003c\/p\u003e \u003cp\u003e3.2 Biological and evolutionary insights from genomics 57\u003c\/p\u003e \u003cp\u003e3.3 Fundamentals of nutrition: carbon- and energy-source utilization provide a foundation for physiological ecology 69\u003c\/p\u003e \u003cp\u003e3.4 Selective pressures: ecosystem nutrient fluxes regulate the physiological status and composition of microbial communities 71\u003c\/p\u003e \u003cp\u003e3.5 Cellular responses to starvation: resting stages, environmental sensing circuits, gene regulation, dormancy, and slow growth 76\u003c\/p\u003e \u003cp\u003e3.6 A planet of complex mixtures in chemical disequilibrium 86\u003c\/p\u003e \u003cp\u003e3.7 A thermodynamic hierarchy describing biosphere selective pressures, energy sources, and biogeochemical reactions 91\u003c\/p\u003e \u003cp\u003e3.8 Using the thermodynamic hierarchy of half reactions to predict biogeochemical reactions in time and space 93\u003c\/p\u003e \u003cp\u003e3.9 Overview of metabolism and the “logic of electron transport” 104\u003c\/p\u003e \u003cp\u003e3.10 The flow of carbon and electrons in anaerobic food chains: syntrophy is the rule 105\u003c\/p\u003e \u003cp\u003e3.11 The diversity of lithotrophic reactions 109\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 A Survey of the Earth’s Microbial Habitats 117\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Terrestrial biomes 118\u003c\/p\u003e \u003cp\u003e4.2 Soils: geographic features relevant to both vegetation and microorganisms 120\u003c\/p\u003e \u003cp\u003e4.3 Aquatic habitats 124\u003c\/p\u003e \u003cp\u003e4.4 Subsurface habitats: oceanic and terrestrial 131\u003c\/p\u003e \u003cp\u003e4.5 Defining the prokaryotic biosphere: where do prokaryotes occur on Earth? 141\u003c\/p\u003e \u003cp\u003e4.6 Life at the micron scale: an excursion into the microhabitat of soil microorganisms 145\u003c\/p\u003e \u003cp\u003e4.7 Extreme habitats for life and microbiological adaptations 151\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Microbial Diversity: Who is Here and How do we Know? 162\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Defining cultured and uncultured microorganisms 163\u003c\/p\u003e \u003cp\u003e5.2 Approaching a census: an introduction to the environmental microbiological “toolbox” 167\u003c\/p\u003e \u003cp\u003e5.3 Criteria for census taking: recognition of distinctive microorganisms (species) 170\u003c\/p\u003e \u003cp\u003e5.4 Proceeding toward census taking and measures of microbial diversity 175\u003c\/p\u003e \u003cp\u003e5.5 The tree of life: our view of evolution’s blueprint for biological diversity 181\u003c\/p\u003e \u003cp\u003e5.6 A Sampling of key traits of cultured microorganisms from the domains \u003ci\u003eEukarya, Bacteria, \u003c\/i\u003eand \u003ci\u003eArchaea \u003c\/i\u003e185\u003c\/p\u003e \u003cp\u003e5.7 Placing the “uncultured majority” on the tree of life: what have nonculture-based investigations revealed? 205\u003c\/p\u003e \u003cp\u003e5.8 Viruses: an overview of biology, ecology, and diversity 213\u003c\/p\u003e \u003cp\u003e5.9 Microbial diversity illustrated by genomics, horizontal gene transfer, and cell size 220\u003c\/p\u003e \u003cp\u003e5.10 Biogeography of microorganisms 224\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Generating and Interpreting Information in Environmental Microbiology: Methods and Their\u003c\/b\u003e \u003cb\u003eLimitations 238\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 How do we know? 239\u003c\/p\u003e \u003cp\u003e6.2 Perspectives from a century of scholars and enrichment-cultivation procedures 239\u003c\/p\u003e \u003cp\u003e6.3 Constraints on knowledge imposed by ecosystem complexity 243\u003c\/p\u003e \u003cp\u003e6.4 Environmental microbiology’s “Heisenberg uncertainty principle”: model systems and their risks 245\u003c\/p\u003e \u003cp\u003e6.5 Fieldwork: being sure sampling procedures are compatible with analyses and goals 247\u003c\/p\u003e \u003cp\u003e6.6 Blending and balancing disciplines from field geochemistry to pure cultures 253\u003c\/p\u003e \u003cp\u003e6.7 Overview of methods for determining the position and composition of microbial communities 257\u003c\/p\u003e \u003cp\u003e6.8 Methods for determining in situ biogeochemical activities and when they occur 276\u003c\/p\u003e \u003cp\u003e6.9 Cloning-based Metagenomics and related methods: procedures and insights 280\u003c\/p\u003e \u003cp\u003e6.10 cloning-free, next-generation sequencing and omics methods: procedures and insights 290\u003c\/p\u003e \u003cp\u003e6.11 Discovering the organisms responsible for particular ecological processes: linking identity with activity 325\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Microbial Biogeochemistry: A Grand Synthesis 356\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Mineral connections: the roles of inorganic elements in life processes 357\u003c\/p\u003e \u003cp\u003e7.2 Greenhouse gases and lessons from biogeochemical modeling 361\u003c\/p\u003e \u003cp\u003e7.3 The “stuff of life”: identifying the pools of biosphere materials whose microbiological transformations drive the biogeochemical cycles 372\u003c\/p\u003e \u003cp\u003e7.4 Elemental biogeochemical cycles: concepts and physiological processes 393\u003c\/p\u003e \u003cp\u003e7.5 Cellular mechanisms of microbial biogeochemical pathways 409\u003c\/p\u003e \u003cp\u003e7.6 Mass balance approaches to elemental cycles 418\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Special and Applied Topics in Environmental Microbiology 432\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Other organisms as microbial habitats: ecological relationships 432\u003c\/p\u003e \u003cp\u003e8.2 Microbial residents of plants and humans 449\u003c\/p\u003e \u003cp\u003e8.3 Biodegradation and bioremediation 461\u003c\/p\u003e \u003cp\u003e8.4 Biofilms 489\u003c\/p\u003e \u003cp\u003e8.5 Evolution of catabolic pathways for organic contaminants 493\u003c\/p\u003e \u003cp\u003e8.6 Environmental biotechnology: overview and nine case studies 499\u003c\/p\u003e \u003cp\u003e8.7 Antibiotic resistance 514\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Future Frontiers in Environmental Microbiology 538\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 The influence of systems biology on environmental microbiology 538\u003c\/p\u003e \u003cp\u003e9.2 Ecological niches and their genetic basis 546\u003c\/p\u003e \u003cp\u003e9.3 Concepts help define future progress in environmental microbiology 551\u003c\/p\u003e \u003cp\u003eGlossary 557\u003c\/p\u003e \u003cp\u003eIndex 564\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":48866370814295,"sku":"9781118439630","price":98.96,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118439630.jpg?v=1722278328"},{"product_id":"essential-developmental-biology-9781119512851","title":"Essential Developmental Biology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eESSENTIAL DEVELOPMENTAL BIOLOGY Discover the foundations of developmental biology with this up to date and focused resource from two leading experts The newly revised Fourth Edition of Essential Developmental Biology delivers the fundamentals of the developmental biology of animals. Designed as a core text for undergraduate students in their first to fourth years, as well as graduate students in their first year, the book is suited to both biologically based and medically oriented courses. The distinguished authors presume no prior knowledge of development, animal structure, or histology. The new edition incorporates modern single cell transcriptome sequencing and CRISPR\/Cas9, as well as other methods for targeted genetic manipulation. The existing material has also been reorganized to provide for easier reading and learning for students. The book avoids discussions of history and experimental priority and emphasizes instead the modern advances in developmental biology. The authors have kept the text short and focused on the areas truly central to developmental biology. Readers will benefit from the inclusion of such topics as: A thorough discussion of the groundwork of developmental biology, including developmental genetics, cell signaling and commitment, and cell and molecular biology techniques An exploration of major model organisms, including Xenopus, the zebrafish, the chick, the mouse, the human, Drosophila, and Caenorhabditis elegans A treatment of organogenesis, including postnatal development, and the development of the nervous system, mesodermal organs, endodermal organs, and imaginal discs in drosophila A final section on growth, stem cell biology, evolution, and regeneration Perfect for undergraduate students, especially those preparing to enter teaching or graduate studies in developmental biology, Essential Developmental Biology will also earn a place in the libraries of those in the pharmaceutical industry expected to be able to evaluate assays based on developmental systems.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface, ix\u003c\/p\u003e \u003cp\u003eAbout the companion website, xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 1: Groundwork, 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 The excitement of developmental biology, 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWhere the subject came from, 3\u003c\/p\u003e \u003cp\u003eImpact of developmental biology, 4\u003c\/p\u003e \u003cp\u003eFuture impact, 5\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 How development works, 7\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eUltrashort summary, 7\u003c\/p\u003e \u003cp\u003eGametogenesis, 10\u003c\/p\u003e \u003cp\u003eEarly development, 13\u003c\/p\u003e \u003cp\u003eGrowth and death, 19\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Approaches to development: developmental genetics, 25\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDevelopmental mutants, 25\u003c\/p\u003e \u003cp\u003eSex chromosomes, 27\u003c\/p\u003e \u003cp\u003eMaternal and zygotic, 27\u003c\/p\u003e \u003cp\u003eGenetic pathways, 28\u003c\/p\u003e \u003cp\u003eGenetic mosaics, 30\u003c\/p\u003e \u003cp\u003eScreening for mutants, 31\u003c\/p\u003e \u003cp\u003eCloning of genes, 32\u003c\/p\u003e \u003cp\u003eGain-and loss-of-function experiments, 32\u003c\/p\u003e \u003cp\u003eTransgenesis, 32\u003c\/p\u003e \u003cp\u003eOther gain-of- function techniques, 34\u003c\/p\u003e \u003cp\u003eTargeted mutagenesis, 34\u003c\/p\u003e \u003cp\u003eOther loss-of- function systems, 35\u003c\/p\u003e \u003cp\u003eGene duplication, 36\u003c\/p\u003e \u003cp\u003eLimitations of developmental genetics, 37\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Approaches to development: experimental embryology and its molecular basis, 39\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNormal development, 39\u003c\/p\u003e \u003cp\u003eDevelopmental commitment, 42\u003c\/p\u003e \u003cp\u003eCriteria for proof, 48\u003c\/p\u003e \u003cp\u003eTranscription factors, 48\u003c\/p\u003e \u003cp\u003eTranscription factor families, 50\u003c\/p\u003e \u003cp\u003eOther controls of gene activity, 51\u003c\/p\u003e \u003cp\u003eSignaling systems, 51\u003c\/p\u003e \u003cp\u003eGenetic regulatory networks, 57\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Approaches to development: cell and molecular biology techniques, 61\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMicroscopy, 61\u003c\/p\u003e \u003cp\u003eOptical techniques, 61\u003c\/p\u003e \u003cp\u003eConfocal, multi-photon, and light sheet microscopes, 63\u003c\/p\u003e \u003cp\u003eImage capture, 63\u003c\/p\u003e \u003cp\u003eAnatomical and histological methods, 64\u003c\/p\u003e \u003cp\u003eMicroinjection, 66\u003c\/p\u003e \u003cp\u003eStudy of gene expression by molecular biology methods, 67\u003c\/p\u003e \u003cp\u003eStudy of gene expression by in situ methods, 72\u003c\/p\u003e \u003cp\u003eReporter genes, 75\u003c\/p\u003e \u003cp\u003eCell-labeling methods, 76\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Cells into tissues, 81\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eCells in embryos, 81\u003c\/p\u003e \u003cp\u003eCytoskeleton, 82\u003c\/p\u003e \u003cp\u003eSmall GTP-binding proteins, 84\u003c\/p\u003e \u003cp\u003eExtracellular matrix, 84\u003c\/p\u003e \u003cp\u003eCell movement, 85\u003c\/p\u003e \u003cp\u003eEpithelial organization, 86\u003c\/p\u003e \u003cp\u003eMorphogenetic processes, 88\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 2: Major model organisms, 97\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Major model organisms, 99\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe big six, 99\u003c\/p\u003e \u003cp\u003eAccess and micromanipulation, 101\u003c\/p\u003e \u003cp\u003eGenetics and genomes, 101\u003c\/p\u003e \u003cp\u003eRelevance and tempo, 102\u003c\/p\u003e \u003cp\u003eOther organisms, 102\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Xenopus, 107\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eOogenesis, maturation, and fertilization, 108\u003c\/p\u003e \u003cp\u003eNormal development, 109\u003c\/p\u003e \u003cp\u003eFate maps, 114\u003c\/p\u003e \u003cp\u003eExperimental methods, 115\u003c\/p\u003e \u003cp\u003eProcesses of regional specification, 119\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 The zebrafish, 135\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNormal development, 135\u003c\/p\u003e \u003cp\u003eFate map, 140\u003c\/p\u003e \u003cp\u003eGenetics, 141\u003c\/p\u003e \u003cp\u003eReverse genetic methods, 144\u003c\/p\u003e \u003cp\u003eEmbryological techniques, 145\u003c\/p\u003e \u003cp\u003eRegional specification, 145\u003c\/p\u003e \u003cp\u003eOther roles of the zebrafish, 150\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 The chick, 153\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNormal development, 154\u003c\/p\u003e \u003cp\u003eFate map, 158\u003c\/p\u003e \u003cp\u003eRegional specification of the early embryo, 159\u003c\/p\u003e \u003cp\u003eDescription of organogenesis in the chick, 164\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 The mouse, 173\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMammalian fertilization, 173\u003c\/p\u003e \u003cp\u003eNormal development of the mouse, 177\u003c\/p\u003e \u003cp\u003eFate map, 184\u003c\/p\u003e \u003cp\u003eRegional specification in the mouse embryo, 185\u003c\/p\u003e \u003cp\u003eTransgenic mice, 190\u003c\/p\u003e \u003cp\u003eEmbryonic stem cells, 192\u003c\/p\u003e \u003cp\u003eKnockouts and knock-ins, 192\u003c\/p\u003e \u003cp\u003eNuclear transplantation and imprinting, 196\u003c\/p\u003e \u003cp\u003eX-inactivation, 196\u003c\/p\u003e \u003cp\u003eTeratocarcinoma, 198\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Human early development, 203\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHuman reproduction, 203\u003c\/p\u003e \u003cp\u003ePreimplantation development, 205\u003c\/p\u003e \u003cp\u003eHuman embryonic stem cells, 207\u003c\/p\u003e \u003cp\u003eHuman postimplantation development, 208\u003c\/p\u003e \u003cp\u003ePostimplantation diagnosis: chorionic villus sampling and amniocentesis, 211\u003c\/p\u003e \u003cp\u003eEthics of human development, 211\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Drosophila, 217\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eInsects, 217\u003c\/p\u003e \u003cp\u003eNormal development, 219\u003c\/p\u003e \u003cp\u003eFate map, 222\u003c\/p\u003e \u003cp\u003ePole plasm, 224\u003c\/p\u003e \u003cp\u003eDrosophila developmental genetics, 224\u003c\/p\u003e \u003cp\u003eThe developmental program, 227\u003c\/p\u003e \u003cp\u003eThe dorsoventral pattern, 228\u003c\/p\u003e \u003cp\u003eThe anteroposterior system, 232\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Caenorhabditis elegans, 247\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAdult anatomy, 248\u003c\/p\u003e \u003cp\u003eEmbryonic development, 249\u003c\/p\u003e \u003cp\u003eRegional specification in the embryo, 251\u003c\/p\u003e \u003cp\u003eAnalysis of postembryonic development, 259\u003c\/p\u003e \u003cp\u003eThe germ line, 262\u003c\/p\u003e \u003cp\u003eProgrammed cell death, 264\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 3: Organogenesis, 269\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Techniques for studying organogenesis and postnatal development, 271\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eGenetics, 271\u003c\/p\u003e \u003cp\u003eClonal analysis, 275\u003c\/p\u003e \u003cp\u003eTissue and organ culture, 278\u003c\/p\u003e \u003cp\u003eCell analysis and separation, 279\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Development of the nervous system, 283\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eOverall structure and cell types, 283\u003c\/p\u003e \u003cp\u003eRegional specification, 286\u003c\/p\u003e \u003cp\u003eNeurogenesis and gliogenesis, 292\u003c\/p\u003e \u003cp\u003eThe neural crest, 299\u003c\/p\u003e \u003cp\u003eDevelopment of neuronal connectivity, 303\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Development of mesodermal organs, 315\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSomitogenesis, 315\u003c\/p\u003e \u003cp\u003eMyogenesis, 322\u003c\/p\u003e \u003cp\u003eThe kidney, 323\u003c\/p\u003e \u003cp\u003eGerm cell and gonadal development, 326\u003c\/p\u003e \u003cp\u003eSex determination, 330\u003c\/p\u003e \u003cp\u003eLimb development, 330\u003c\/p\u003e \u003cp\u003eBlood and blood vessels, 340\u003c\/p\u003e \u003cp\u003eThe heart, 343\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Development of endodermal organs, 355\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNormal development, 355\u003c\/p\u003e \u003cp\u003eOrganization of the gut tube, 356\u003c\/p\u003e \u003cp\u003eFate map of the endoderm, 359\u003c\/p\u003e \u003cp\u003eExperimental analysis of endoderm development, 359\u003c\/p\u003e \u003cp\u003eThe pancreas, 366\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Drosophila imaginal discs, 373\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMetamorphosis, 373\u003c\/p\u003e \u003cp\u003eGenetic study of larval development, 374\u003c\/p\u003e \u003cp\u003eDisc development, 378\u003c\/p\u003e \u003cp\u003eCompartments and selector genes, 378\u003c\/p\u003e \u003cp\u003eRegional patterning of the wing disc, 381\u003c\/p\u003e \u003cp\u003eRegeneration and transdetermination, 384\u003c\/p\u003e \u003cp\u003eMorphogen gradients and polarity, 387\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 4: Growth, evolution, regeneration, 391\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Tissue organization and stem cells, 393\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eTypes of tissue, 393\u003c\/p\u003e \u003cp\u003eTissue renewal, 397\u003c\/p\u003e \u003cp\u003eStem cells, 401\u003c\/p\u003e \u003cp\u003eIntestinal epithelium, 403\u003c\/p\u003e \u003cp\u003eEpidermis, 408\u003c\/p\u003e \u003cp\u003eHair follicles, 410\u003c\/p\u003e \u003cp\u003eHematopoietic system, 415\u003c\/p\u003e \u003cp\u003eMesenchymal stem cells and “transdifferentiation”, 419\u003c\/p\u003e \u003cp\u003eSpermatogonia, 419\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Growth, aging, and cancer, 425\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eGrowth: control of size and proportion, 425\u003c\/p\u003e \u003cp\u003eBiochemical pathways of growth control, 426\u003c\/p\u003e \u003cp\u003eGrowth control in insects, 429\u003c\/p\u003e \u003cp\u003eGrowth control in mammals, 431\u003c\/p\u003e \u003cp\u003eLiver regeneration, 433\u003c\/p\u003e \u003cp\u003eGrowth in stature, 434\u003c\/p\u003e \u003cp\u003eAging, 436\u003c\/p\u003e \u003cp\u003eCell autonomous processes, 437\u003c\/p\u003e \u003cp\u003eThe insulin pathway and aging, 438\u003c\/p\u003e \u003cp\u003eCaloric restriction, 438\u003c\/p\u003e \u003cp\u003eCancer, 440\u003c\/p\u003e \u003cp\u003eClassification of tumors and precursor lesions, 440\u003c\/p\u003e \u003cp\u003eMolecular biology of cancer, 442\u003c\/p\u003e \u003cp\u003eCancer stem cells, 443\u003c\/p\u003e \u003cp\u003eCancer progression, 444\u003c\/p\u003e \u003cp\u003eCancer therapy, 445\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Pluripotent stem cells and their applications, 449\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHuman embryonic stem cells, 449\u003c\/p\u003e \u003cp\u003eInduced pluripotent stem cells, 451\u003c\/p\u003e \u003cp\u003eSomatic cell nuclear transfer, 453\u003c\/p\u003e \u003cp\u003eDirect reprogramming, 454\u003c\/p\u003e \u003cp\u003eApplications of human pluripotent stem cells, 455\u003c\/p\u003e \u003cp\u003eCell transplantation therapy, 457\u003c\/p\u003e \u003cp\u003eCell transplantation therapies using pluripotent stem cells, 459\u003c\/p\u003e \u003cp\u003eTransplantation therapy for diabetes, 460\u003c\/p\u003e \u003cp\u003eRetinal pigment epithelium, 462\u003c\/p\u003e \u003cp\u003eSpinal repair, 463\u003c\/p\u003e \u003cp\u003eCardiomyocytes, 463\u003c\/p\u003e \u003cp\u003eParkinson’s disease, 463\u003c\/p\u003e \u003cp\u003eIntroduction of new therapies, 465\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 Evolution and development, 469\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMacroevolution, 470\u003c\/p\u003e \u003cp\u003eMolecular taxonomy, 471\u003c\/p\u003e \u003cp\u003ePhylogeny of animals, 472\u003c\/p\u003e \u003cp\u003eThe fossil record, 473\u003c\/p\u003e \u003cp\u003eThe primordial animal, 474\u003c\/p\u003e \u003cp\u003eBasal animals, 479\u003c\/p\u003e \u003cp\u003eWhat really happened in evolution?, 481\u003c\/p\u003e \u003cp\u003eSegmented body plans and Hox genes, 482\u003c\/p\u003e \u003cp\u003eInsect wings and legs, 483\u003c\/p\u003e \u003cp\u003eAtavisms, 483\u003c\/p\u003e \u003cp\u003eVertebrate limbs, 485\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 Regeneration of missing parts, 491\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eTypes of regeneration, 491\u003c\/p\u003e \u003cp\u003eDistribution of regenerative capacity, 491\u003c\/p\u003e \u003cp\u003ePlanarian regeneration, 492\u003c\/p\u003e \u003cp\u003eInsect limb regeneration, 497\u003c\/p\u003e \u003cp\u003eVertebrate limb regeneration, 499\u003c\/p\u003e \u003cp\u003eThe process of limb regeneration, 499\u003c\/p\u003e \u003cp\u003eThe source of cells for regeneration, 501\u003c\/p\u003e \u003cp\u003eRegeneration of regional pattern, 502\u003c\/p\u003e \u003cp\u003eRegeneration: ancestral or adaptive property?, 508\u003c\/p\u003e \u003cp\u003eGeneral properties of regeneration, 509\u003c\/p\u003e \u003cp\u003eGlossary, 513\u003c\/p\u003e \u003cp\u003eIndex, 527\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":48866400043351,"sku":"9781119512851","price":94.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119512851.jpg?v=1722278462"}],"url":"https:\/\/bookcurl.com\/collections\/biochemistry.oembed?page=52","provider":"Book Curl","version":"1.0","type":"link"}